Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
In the last 90 days, Opko Health, Inc. insiders filed 0 open-market purchases and 1 sale; 223 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
Key figures
- Market capClose on Nov 10, 2026
- $1.27B
- Insider buysOpen market, last 90 days
- 0
- Insider sellsLast 90 days, $24.6K in total
- 1
- 13F holdersQ2 2026, −7 vs. previous quarter
- 223
- 13F valueReported value at the end of Q2 2026
- $303.4M
- Superinvestors holdingAt the end of Q2 2026
- 0
Price chart
Financials
See financial statementsFrom SEC filings, in USD.
- Revenue, FY2025
- $606.9M
- −14.9% year over year
- Net income, FY2025
- -$225.7M
- No comparable prior period
- Free cash flow, FY2025
- -$190.8M
- No comparable prior period
- Revenue, Q3 FY2026
- $65.4M
- −56.9% year over year
Short interest
See short dataFrom FINRA, settlement date Oct 30, 2026.
- Short interest
- 32.8M
- Shares sold short
- Change
- −1.16M
- −3.4% vs. previous
- Days to cover
- 9.23
- At average daily volume
Superinvestors holding OPK, Q2 2026
Go to the superinvestors tabNo superinvestor reported holding OPK at the end of Q2 2026.
Latest insider trades
See all insider tradesOpen-market purchases and sales by Opko Health, Inc. insiders from Form 4, newest first.
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| Nov 5, 2026 (view filing)4:07 PM ET | Nov 5 | Same day | Paganelli John ADirector | SSale | −4.43K | $1.78 | −$7.88K | −1.1%389.9K after | |
| Nov 5, 2026 (view filing)4:07 PM ET | Nov 5 | Same day | Paganelli John ADirector | SSale | −9.18K | $1.82 | −$16.7K | −100.0%0 after | |
| Mar 20, 2026 (view filing) | Mar 20 | Same day | Paganelli John ADirector | PPurchase | +10.0K | $1.14 | +$11.4K | +2.6%394.3K after | |
| Nov 21, 2025 (view filing)5:07 PM ET | Nov 21 | Same day | Frost Phillip MD Et Al and 1 otherCEO & Chairman | PPurchase | +580.0K | $1.33 | +$768.8K | +0.3%216.7M after | 5 lots |
| Nov 20, 2025 (view filing)6:10 PM ET | Nov 20 | Same day | Frost Phillip MD Et Al and 1 otherCEO & Chairman | PPurchase | +580.0K | $1.33 | +$771.3K | +0.3%216.1M after | 7 lots |
| Nov 19, 2025 (view filing)5:02 PM ET | Nov 19 | Same day | Frost Phillip MD Et Al and 1 otherCEO & Chairman | PPurchase | +580.0K | $1.31 | +$759.1K | +0.3%215.5M after | 9 lots |
| Nov 18, 2025 (view filing)5:18 PM ET | Nov 18 | Same day | Frost Phillip MD Et Al and 1 otherCEO & Chairman | PPurchase | +533.3K | $1.27 | +$678.9K | +0.2%215.0M after | 11 lots |
| Oct 31, 2025 (view filing)5:15 PM ET | Oct 31 | Same day | Frost Phillip MD Et Al and 1 otherCEO & Chairman | PPurchase | +150.0K | $1.42 | +$213.4K | +0.1%214.4M after | |
| Aug 8, 2025 (view filing)4:56 PM ET | Aug 8 | Same day | Frost Phillip MD Et Al and 1 otherCEO & Chairman | PPurchase | +675.0K | $1.32 | +$891.0K | +0.3%214.7M after | |
| Apr 10, 2025 (view filing)5:07 PM ET | Apr 10 | Same day | Frost Phillip MD Et Al and 1 otherCEO & Chairman | PPurchase | +125.0K | $1.36 | +$169.7K | +0.1%214.0M after |
Top 10 13F holders, Q2 2026
See all 223 holdersThe largest institutional positions in Opko Health, Inc. at the end of Q2 2026; share changes are against Q1 2026.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Rubric Capital Management LP | 47,791,243 | $71.7M | 0.66% | 00.0% | Unchanged |
| BlackRock, Inc. | 36,978,893 | $55.5M | 0.00% | +746,670+2.1% | Added |
| Vanguard Capital Management LLC | 14,968,930 | $22.5M | 0.00% | +469,766+3.2% | Added |
| Vanguard Portfolio Management LLC | 14,934,924 | $22.4M | 0.00% | +165,205+1.1% | Added |
| Geode Capital Management, LLC | 11,581,027 | $17.4M | 0.00% | +279,526+2.5% | Added |
| State Street Corp | 10,309,070 | $15.5M | 0.00% | +807,693+8.5% | Added |
| Goldman Sachs Group Inc | 7,035,492 | $10.6M | 0.00% | −639,534−8.3% | Reduced |
| UBS Group AG | 5,006,284 | $7.51M | 0.00% | −1,065,148−17.5% | Reduced |
| Whitefort Capital Management, LP | 4,511,412 | $6.77M | 1.67% | +258,072+6.1% | Added |
| Northern Trust Corp | 3,756,163 | $5.63M | 0.00% | +136,817+3.8% | Added |
Holders of 5% or more of OPK
See all 2 holders and filingsHolders whose latest Schedule 13D or 13G filing reports 5% or more of Opko Health, Inc..
| Holder | Latest form | Stake | Change | First filed | Latest filing | Filing |
|---|---|---|---|---|---|---|
| Frost Phillip MD Et Al | 13D/A | 34.10%255.4M shares | +1.30 ppfrom 32.80% | Aug 19, 20229 filings | Jul 1, 2026 | SEC |
| Rubric Capital Management LP | 13G/A | 6.03%47.8M shares | – | Nov 13, 20242 filings | Jul 9, 2025 | SEC |