Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Opko Health, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 255
- +21 vs. Q4 2024
- Shares held
- 242.1M
- +46.0M (+23.4%) vs. Q4 2024
- Total value
- $401.4M
- +$113.2M (+39.3%) vs. Q4 2024
- New holders
- 44
- 76 more added
- Sold out
- 23
- 57 more reduced
1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Rubric Capital Management LP | 48,706,640 | $80.9M | 1.45% | 00.0% | Unchanged |
| Vanguard Group Inc | 29,500,071 | $49.0M | 0.00% | +293,740+1.0% | Added |
| BlackRock, Inc. | 27,604,974 | $45.8M | 0.00% | −563,638−2.0% | Reduced |
| Sculptor Capital LP | 12,717,400 | $21.1M | 0.47% | +12,717,400 | New |
| Weiss Asset Management LP | 11,192,800 | $18.6M | 0.50% | +11,192,800 | New |
| Geode Capital Management, LLC | 8,428,840 | $14.0M | 0.00% | +43,622+0.5% | Added |
| State Street Corp | 8,139,496 | $13.5M | 0.00% | −935,402−10.3% | Reduced |
| Deerfield Management Company, L.P. (Series C) | 6,906,362 | $11.5M | 0.23% | +6,906,362 | New |
| Millennium Management LLC | 6,386,911 | $10.6M | 0.01% | +1,798,385+39.2% | Added |
| Marshall Wace, LLP | 4,896,428 | $8.13M | 0.01% | +3,974,941+431.4% | Added |
| D. E. Shaw & Co., Inc. | 4,731,688 | $7.85M | 0.01% | +4,731,688 | New |
| Bank of America Corp | 4,158,882 | $6.90M | 0.00% | +3,577,300+615.1% | Added |
| Morgan Stanley | 4,108,488 | $6.82M | 0.00% | +940,546+29.7% | Added |
| Goldman Sachs Group Inc | 4,001,214 | $6.64M | 0.00% | +161,394+4.2% | Added |
| Lazard Asset Management LLC | 3,609,314 | $5.99M | 0.01% | +1,060,647+41.6% | Added |
| Northern Trust Corp | 3,529,392 | $5.86M | 0.00% | −168,382−4.6% | Reduced |
| Charles Schwab Investment Management Inc | 2,741,986 | $4.55M | 0.00% | −755,420−21.6% | Reduced |
| JPMorgan Chase & Co | 2,501,332 | $4.15M | 0.00% | +926,361+58.8% | Added |
| UBS Group AG | 2,417,053 | $4.01M | 0.00% | −2,405,794−49.9% | Reduced |
| Dimensional Fund Advisors LP | 2,222,512 | $3.69M | 0.00% | −46,154−2.0% | Reduced |
| Citadel Advisors LLC | 1,856,526 | $3.08M | 0.00% | −1,353,764−42.2% | Reduced |
| AWM Investment Company, Inc. | 1,850,000 | $3.07M | 0.42% | +550,000+42.3% | Added |
| Graham Capital Management, L.P. | 1,810,392 | $3.01M | 0.10% | +1,810,392 | New |
| Y.D. More Investments Ltd | 1,772,947 | $2.97M | 0.26% | +377,179+27.0% | Added |
| Two Sigma Investments, LP | 1,645,775 | $2.73M | 0.01% | −1,792−0.1% | Reduced |
| Invesco Ltd. | 1,623,600 | $2.70M | 0.00% | +69,111+4.4% | Added |
| AQR Capital Management LLC | 1,608,906 | $2.67M | 0.00% | +1,324,988+466.7% | Added |
| Altshuler Shaham Ltd | 1,454,221 | $2.44M | 0.06% | +43,202+3.1% | Added |
| Nuveen, LLC | 1,376,881 | $2.29M | 0.00% | +1,376,881 | New |
| Gsa Capital Partners LLP | 1,343,701 | $2.23M | 0.20% | +261,495+24.2% | Added |
| PFG Investments, LLC | 1,217,360 | $2.02M | 0.13% | +56,475+4.9% | Added |
| Bank of New York Mellon Corp | 1,020,521 | $1.69M | 0.00% | −4,386−0.4% | Reduced |
| Assenagon Asset Management S.A. | 935,100 | $1.56M | 0.00% | +78,362+9.1% | Added |
| BNP Paribas Arbitrage, SA | 891,145 | $1.48M | 0.00% | +839,296+1,618.7% | Added |
| Clearstead Advisors, LLC | 883,042 | $1.47M | 0.02% | 00.0% | Unchanged |
| HRT Financial LP | 880,240 | $1.46M | 0.01% | +210,604+31.5% | Added |
| Tejara Capital Ltd | 860,344 | $1.43M | 0.70% | −365,306−29.8% | Reduced |
| Voya Investment Management LLC | 809,876 | $1.34M | 0.00% | −445,158−35.5% | Reduced |
| UBS Asset Management Americas Inc | 781,634 | $1.30M | 0.00% | +28,254+3.8% | Added |
| Susquehanna International Group, LLP | 756,146 | $1.26M | 0.00% | +611,010+421.0% | Added |
| Swiss National Bank | 661,155 | $1.10M | 0.00% | −24,300−3.5% | Reduced |
| Advisor Group Holdings, Inc. | 651,809 | $1.08M | 0.00% | +119,983+22.6% | Added |
| Two Sigma Advisers, LP | 551,697 | $915.8K | 0.00% | +170,500+44.7% | Added |
| Jane Street Group, LLC | 549,338 | $911.9K | 0.00% | −2,257,583−80.4% | Reduced |
| Alliancebernstein L.P. | 504,390 | $837.3K | 0.00% | +129,070+34.4% | Added |
| Price T Rowe Associates Inc | 501,668 | $833.0K | 0.00% | +46,147+10.1% | Added |
| Norges Bank | 494,257 | $820.5K | 0.00% | −633,211−56.2% | Reduced |
| Rhumbline Advisers | 490,279 | $813.9K | 0.00% | −28,544−5.5% | Reduced |
| Commonwealth Equity Services, LLC | 479,830 | $797.0K | 0.00% | +45,795+10.6% | Added |
| X-Square Capital, LLC | 460,425 | $764.0K | 0.33% | +298,699+184.7% | Added |
| Barclays PLC | 391,991 | $650.7K | 0.00% | −524,377−57.2% | Reduced |
| SG Americas Securities, LLC | 352,276 | $585.0K | 0.00% | +352,276 | New |
| Legal & General Group Plc | 350,098 | $581.2K | 0.00% | −20,340−5.5% | Reduced |
| Exchange Traded Concepts, LLC | 338,948 | $562.7K | 0.01% | −12,948−3.7% | Reduced |
| California State Teachers Retirement System | 324,117 | $538.0K | 0.00% | 00.0% | Unchanged |
| Verition Fund Management LLC | 317,946 | $527.8K | 0.00% | +317,946 | New |
| XTX Topco Ltd | 309,290 | $513.4K | 0.03% | +114,486+58.8% | Added |
| Squarepoint Ops LLC | 301,861 | $501.1K | 0.00% | +166,523+123.0% | Added |
| Deutsche Bank AG | 281,647 | $467.5K | 0.00% | −28,220−9.1% | Reduced |
| Citigroup Inc | 263,901 | $438.1K | 0.00% | −6,213−2.3% | Reduced |
| Tudor Investment Corp Et Al | 244,821 | $406.4K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 236,609 | $393.0K | 0.00% | −5,319−2.2% | Reduced |
| Wells Fargo & Company | 230,015 | $381.8K | 0.00% | +753+0.3% | Added |
| Engineers Gate Manager LP | 216,357 | $359.2K | 0.01% | −198,096−47.8% | Reduced |
| Janus Henderson Group PLC | 206,314 | $351.8K | 0.00% | 00.0% | Unchanged |
| Quantbot Technologies LP | 210,079 | $348.7K | 0.01% | +210,079 | New |
| ExodusPoint Capital Management, LP | 209,300 | $347.0K | 0.00% | +35,600+20.5% | Added |
| Zazove Associates LLC | 207,600 | $344.6K | 0.03% | +202,700+4,136.7% | Added |
| Intech Investment Management LLC | 204,317 | $339.2K | 0.00% | +2,839+1.4% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 201,345 | $334.2K | 0.00% | +179,045+802.9% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 189,194 | $314.1K | 0.00% | +2,411+1.3% | Added |
| Ieq Capital, LLC | 183,363 | $304.4K | 0.00% | +147,944+417.7% | Added |
| Capula Management Ltd | 182,512 | $303.0K | 0.00% | +182,512 | New |
| State Board of Administration of Florida Retirement System | 176,260 | $292.6K | 0.00% | 00.0% | Unchanged |
| Gamco Investors, Inc. Et Al | 175,000 | $290.5K | 0.00% | 00.0% | Unchanged |
| Gabelli Funds LLC | 170,000 | $282.2K | 0.00% | 00.0% | Unchanged |
| MetLife Investment Management | 164,230 | $272.6K | 0.00% | −37,935−18.8% | Reduced |
| Corebridge Financial, Inc. | 156,247 | $259.4K | 0.00% | −5,687−3.5% | Reduced |
| Teton Advisors, Inc. | 144,500 | $239.9K | 0.15% | −5,500−3.7% | Reduced |
| Numerai GP LLC | 133,187 | $221.1K | 0.04% | −6,568−4.7% | Reduced |
| Manufacturers Life Insurance Company, The | 124,731 | $207.1K | 0.00% | −6,050−4.6% | Reduced |
| Cubist Systematic Strategies, LLC | 119,223 | $197.9K | 0.00% | +114,396+2,369.9% | Added |
| Highline Wealth Partners LLC | 116,680 | $193.7K | 0.07% | 00.0% | Unchanged |
| Van Eck Associates Corp | 113,506 | $188.0K | 0.00% | +6,722+6.3% | Added |
| Comerica Bank | 112,000 | $185.9K | 0.00% | +5,631+5.3% | Added |
| Phoenix Holdings Ltd. | 100,000 | $171.3K | 0.00% | 00.0% | Unchanged |
| Cambridge Investment Research Advisors, Inc. | 103,110 | $171.0K | 0.00% | 00.0% | Unchanged |
| Csenge Advisory Group | 117,000 | $166.1K | 0.01% | 00.0% | Unchanged |
| Intrepid Capital Management Inc | 100,000 | $166.0K | 0.08% | 00.0% | Unchanged |
| Arizona State Retirement System | 97,883 | $162.5K | 0.00% | −3,005−3.0% | Reduced |
| Ameriprise Financial Inc | 94,091 | $156.2K | 0.00% | −300−0.3% | Reduced |
| American Century Companies Inc | 92,785 | $154.0K | 0.00% | +92,785 | New |
| Hollencrest Capital Management | 90,000 | $149.4K | 0.01% | 00.0% | Unchanged |
| Raymond James Financial Inc | 85,370 | $141.7K | 0.00% | −65,300−43.3% | Reduced |
| Balyasny Asset Management LLC | 84,196 | $139.8K | 0.00% | +73,432+682.2% | Added |
| Teacher Retirement System of Texas | 83,766 | $139.1K | 0.00% | +83,766 | New |
| 360 Financial, Inc. | 79,300 | $131.6K | 0.05% | −1,500−1.9% | Reduced |
| Caxton Associates LLP | 78,128 | $129.7K | 0.00% | +78,128 | New |
| Quadrature Capital Ltd | 77,658 | $128.9K | 0.00% | +77,658 | New |
| Police & Firemen's Retirement System of New Jersey | 77,449 | $128.6K | 0.00% | 00.0% | Unchanged |