Opko Health, Inc.

OPK

Exchange: Nasdaq
Industry: Pharmaceutical Preparations
SEC CIK: 0000944809

SEC filings (opens in a new tab)

No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.

Q1 2025 vs. Q4 2024

How the institutions holding Opko Health, Inc. changed between Q4 2024 and Q1 2025.

All holders in Q1 2025 All holders in Q4 2024

13F holders of OPK: Q4 2024 compared with Q1 2025
Measure	Q4 2024	Of which not filed for Q1 2025	Q1 2025	Change
Holders	235	1	255	+21
Shares	197.6M	1.43M	242.1M	+46.0M (+23.4%)
Value	$290.3M	$2.11M	$401.4M	+$113.2M (+39.3%)

1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (44)

Institutions that held Opko Health, Inc. at the end of Q1 2025 but not at the end of Q4 2024.

Institutions new to OPK in Q1 2025
Institution	Shares	Value	% of portfolio
Sculptor Capital LP	12,717,400	$21.1M	0.47%
Weiss Asset Management LP	11,192,800	$18.6M	0.50%
Deerfield Management Company, L.P. (Series C)	6,906,362	$11.5M	0.23%
D. E. Shaw & Co., Inc.	4,731,688	$7.85M	0.01%
Graham Capital Management, L.P.	1,810,392	$3.01M	0.10%
Nuveen, LLC	1,376,881	$2.29M	0.00%
SG Americas Securities, LLC	352,276	$585.0K	0.00%
Verition Fund Management LLC	317,946	$527.8K	0.00%
Quantbot Technologies LP	210,079	$348.7K	0.01%
Capula Management Ltd	182,512	$303.0K	0.00%
American Century Companies Inc	92,785	$154.0K	0.00%
Teacher Retirement System of Texas	83,766	$139.1K	0.00%
Caxton Associates LLP	78,128	$129.7K	0.00%
Quadrature Capital Ltd	77,658	$128.9K	0.00%
Headlands Technologies LLC	52,149	$86.6K	0.01%
Jump Financial, LLC	49,070	$81.5K	0.00%
Inspire Advisors, LLC	47,130	$78.2K	0.01%
Aquatic Capital Management LLC	45,966	$76.3K	0.00%
Voleon Capital Management LP	27,225	$45.2K	0.00%
Pallas Capital Advisors LLC	25,851	$42.9K	0.00%
Jain Global LLC	24,200	$40.2K	0.00%
Toroso Investments, LLC	23,618	$39.2K	0.00%
Cerity Partners LLC	21,528	$35.7K	0.00%
GM Advisory Group, Inc.	20,000	$33.2K	0.00%
Mariner, LLC	17,463	$29.0K	0.00%
CAPROCK Group, Inc.	16,770	$27.8K	0.00%
Oak Thistle LLC	15,636	$26.0K	0.01%
Sanctuary Advisors, LLC	14,191	$23.6K	0.00%
Blueshift Asset Management, LLC	13,870	$23.0K	0.01%
Schonfeld Strategic Advisors LLC	13,100	$21.7K	0.00%
Canada Pension Plan Investment Board	12,900	$21.4K	0.00%
R Squared Ltd	12,290	$20.4K	0.02%
Farringdon Capital, Ltd.	11,834	$19.6K	0.01%
Colony Group, LLC	11,524	$19.1K	0.00%
Gotham Asset Management, LLC	11,056	$18.4K	0.00%
Boothbay Fund Management, LLC	10,930	$18.1K	0.00%
Merit Financial Group, LLC	10,249	$17.0K	0.00%
Grove Bank & Trust	250	$415	0.00%
Medallion Wealth Advisors, LLC	200	$332	0.00%
Harbor Investment Advisory, LLC	180	$299	0.00%
Truvestments Capital LLC	100	$166	0.00%
LRI Investments, LLC	1	$2	0.00%
Bessemer Group Inc	273	$0	0.00%
Washington Growth Strategies LLC	2	–	–

Sold out (23)

Institutions that held Opko Health, Inc. at the end of Q4 2024 and filed for Q1 2025 without it.

Institutions that sold out of OPK in Q1 2025
Institution	Shares, Q4 2024	Value, Q4 2024
Intrinsic Edge Capital Management LLC	1,100,000	$1.62M
Skaana Management L.P.	478,614	$703.6K
Essential Planning, LLC.	331,175	$506.1K
Renaissance Technologies LLC	145,977	$214.6K
Whitefort Capital Management, LP	134,490	$197.7K
Wolverine Trading, LLC	97,722	$143.7K
Y-Intercept (Hong Kong) Ltd	69,591	$102.3K
Brevan Howard Capital Management LP	66,282	$97.4K
Catalyst Funds Management Pty Ltd	61,600	$90.6K
Zacks Investment Management	33,300	$49.0K
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management	20,000	$29.4K
Granite Investment Partners, LLC	14,356	$21.1K
GTS Securities LLC	12,944	$19.0K
Mill Creek Capital Advisors, LLC	12,383	$18.2K
Public Employees Retirement System of Ohio	11,055	$16.3K
Pathstone Holdings, LLC	10,541	$16.2K
McAdam, LLC	10,054	$14.8K
GeoWealth Management, LLC	1,215	$1.79K
Signaturefd, LLC	1,000	$1.47K
Fifth Third Bancorp	550	$809
Sugar Maple Asset Management, LLC	350	$515
Newbridge Financial Services Group, Inc.	100	$147
Cornerstone Planning Group LLC	1	$1

Not filed for Q1 2025 yet (1)

Institutions that held Opko Health, Inc. at the end of Q4 2024 and haven't filed a 13F for Q1 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding OPK in Q4 2024 that haven't filed for Q1 2025
Institution	Shares, Q4 2024	Value, Q4 2024
Nuveen Asset Management, LLC	1,432,404	$2.11M