Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Opko Health, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 235
- +6 vs. Q3 2024
- Shares held
- 197.6M
- +11.0M (+5.9%) vs. Q3 2024
- Total value
- $290.3M
- +$12.4M (+4.4%) vs. Q3 2024
- New holders
- 35
- 66 more added
- Sold out
- 29
- 59 more reduced
5 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Rubric Capital Management LP | 48,706,640 | $71.6M | 1.30% | 00.0% | Unchanged |
| Vanguard Group Inc | 29,206,331 | $42.9M | 0.00% | −11,8190.0% | Reduced |
| BlackRock, Inc. | 28,168,612 | $41.4M | 0.00% | −430,686−1.5% | Reduced |
| State Street Corp | 9,074,898 | $13.3M | 0.00% | +359,388+4.1% | Added |
| Geode Capital Management, LLC | 8,385,218 | $12.3M | 0.00% | +10,473+0.1% | Added |
| UBS Group AG | 4,822,847 | $7.09M | 0.00% | +3,976,423+469.8% | Added |
| Millennium Management LLC | 4,588,526 | $6.75M | 0.01% | +2,112,382+85.3% | Added |
| Goldman Sachs Group Inc | 3,839,820 | $5.64M | 0.00% | +1,097,515+40.0% | Added |
| Northern Trust Corp | 3,697,774 | $5.44M | 0.00% | +164,847+4.7% | Added |
| Charles Schwab Investment Management Inc | 3,497,406 | $5.14M | 0.00% | −714,949−17.0% | Reduced |
| Citadel Advisors LLC | 3,210,290 | $4.72M | 0.00% | +708,616+28.3% | Added |
| Morgan Stanley | 3,167,942 | $4.66M | 0.00% | +1,838,554+138.3% | Added |
| Jane Street Group, LLC | 2,806,921 | $4.13M | 0.01% | +2,276,381+429.1% | Added |
| Lazard Asset Management LLC | 2,548,667 | $3.75M | 0.01% | +1,502,342+143.6% | Added |
| Dimensional Fund Advisors LP | 2,268,666 | $3.33M | 0.00% | −59,914−2.6% | Reduced |
| Two Sigma Investments, LP | 1,647,567 | $2.42M | 0.01% | +949,671+136.1% | Added |
| JPMorgan Chase & Co | 1,574,971 | $2.32M | 0.00% | −261,897−14.3% | Reduced |
| Invesco Ltd. | 1,554,489 | $2.29M | 0.00% | −4,475,485−74.2% | Reduced |
| Nuveen Asset Management, LLC | 1,432,404 | $2.11M | 0.00% | +425,484+42.3% | Added |
| Altshuler Shaham Ltd | 1,411,019 | $2.08M | 0.07% | +1,411,019 | New |
| Y.D. More Investments Ltd | 1,395,768 | $2.06M | 0.19% | −318,077−18.6% | Reduced |
| AWM Investment Company, Inc. | 1,300,000 | $1.91M | 0.23% | 00.0% | Unchanged |
| Voya Investment Management LLC | 1,255,034 | $1.84M | 0.00% | −815,679−39.4% | Reduced |
| Tejara Capital Ltd | 1,225,650 | $1.80M | 1.18% | +124,524+11.3% | Added |
| PFG Investments, LLC | 1,160,885 | $1.71M | 0.11% | +99,795+9.4% | Added |
| Norges Bank | 1,127,468 | $1.66M | 0.00% | 00.0% | Unchanged |
| Intrinsic Edge Capital Management LLC | 1,100,000 | $1.62M | 0.22% | 00.0% | Unchanged |
| Gsa Capital Partners LLP | 1,082,206 | $1.59M | 0.12% | +1,082,206 | New |
| Bank of New York Mellon Corp | 1,024,907 | $1.51M | 0.00% | −39,372−3.7% | Reduced |
| Marshall Wace, LLP | 921,487 | $1.35M | 0.00% | +825,143+856.5% | Added |
| Barclays PLC | 916,368 | $1.35M | 0.00% | +373,032+68.7% | Added |
| Clearstead Advisors, LLC | 883,042 | $1.30M | 0.02% | +500+0.1% | Added |
| Assenagon Asset Management S.A. | 856,738 | $1.27M | 0.00% | −634,254−42.5% | Reduced |
| UBS Asset Management Americas Inc | 753,380 | $1.11M | 0.00% | +148,322+24.5% | Added |
| Swiss National Bank | 685,455 | $1.01M | 0.00% | 00.0% | Unchanged |
| HRT Financial LP | 669,636 | $984.0K | 0.01% | +131,573+24.5% | Added |
| Group One Trading, L.P. | 647,085 | $951.2K | 0.03% | +426,106+192.8% | Added |
| Bank of America Corp | 581,582 | $854.9K | 0.00% | +282,844+94.7% | Added |
| Advisor Group Holdings, Inc. | 531,826 | $781.8K | 0.00% | +488,650+1,131.8% | Added |
| Rhumbline Advisers | 518,823 | $762.7K | 0.00% | −27,794−5.1% | Reduced |
| Skaana Management L.P. | 478,614 | $703.6K | 0.22% | −366,038−43.3% | Reduced |
| Price T Rowe Associates Inc | 455,521 | $670.0K | 0.00% | +18,571+4.3% | Added |
| Commonwealth Equity Services, LLC | 434,035 | $638.0K | 0.00% | −241−0.1% | Reduced |
| Engineers Gate Manager LP | 414,453 | $609.2K | 0.01% | −11,589−2.7% | Reduced |
| Two Sigma Advisers, LP | 381,197 | $560.4K | 0.00% | +8,396+2.3% | Added |
| Alliancebernstein L.P. | 375,320 | $551.7K | 0.00% | −111,399−22.9% | Reduced |
| Legal & General Group Plc | 370,438 | $544.5K | 0.00% | −19,866−5.1% | Reduced |
| Exchange Traded Concepts, LLC | 351,896 | $517.3K | 0.01% | −35,212−9.1% | Reduced |
| Essential Planning, LLC. | 331,175 | $506.1K | 0.00% | +331,175 | New |
| California State Teachers Retirement System | 324,117 | $476.5K | 0.00% | −3,700−1.1% | Reduced |
| Deutsche Bank AG | 309,867 | $455.5K | 0.00% | +100,868+48.3% | Added |
| AQR Capital Management LLC | 283,918 | $417.4K | 0.00% | +206,768+268.0% | Added |
| Citigroup Inc | 270,114 | $397.1K | 0.00% | +31,288+13.1% | Added |
| Tudor Investment Corp Et Al | 244,821 | $359.9K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 241,928 | $356.0K | 0.00% | +19,873+8.9% | Added |
| Wells Fargo & Company | 229,262 | $337.0K | 0.00% | +29,738+14.9% | Added |
| Janus Henderson Group PLC | 206,314 | $304.3K | 0.00% | 00.0% | Unchanged |
| MetLife Investment Management | 202,165 | $297.2K | 0.00% | +58,589+40.8% | Added |
| Intech Investment Management LLC | 201,478 | $296.2K | 0.00% | +74,002+58.1% | Added |
| XTX Topco Ltd | 194,804 | $286.4K | 0.02% | +86,152+79.3% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 186,783 | $274.6K | 0.00% | +8,064+4.5% | Added |
| State Board of Administration of Florida Retirement System | 176,260 | $259.1K | 0.00% | −102,440−36.8% | Reduced |
| Gamco Investors, Inc. Et Al | 175,000 | $257.3K | 0.00% | 00.0% | Unchanged |
| ExodusPoint Capital Management, LP | 173,700 | $255.0K | 0.00% | +173,700 | New |
| Gabelli Funds LLC | 170,000 | $249.9K | 0.00% | 00.0% | Unchanged |
| Corebridge Financial, Inc. | 161,934 | $238.0K | 0.00% | −12,223−7.0% | Reduced |
| X-Square Capital, LLC | 161,726 | $238.0K | 0.10% | −7,825−4.6% | Reduced |
| Raymond James Financial Inc | 150,670 | $221.5K | 0.00% | +150,670 | New |
| Teton Advisors, Inc. | 150,000 | $220.5K | 0.11% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 145,977 | $214.6K | 0.00% | −312,950−68.2% | Reduced |
| Susquehanna International Group, LLP | 145,136 | $213.3K | 0.00% | +17,139+13.4% | Added |
| Numerai GP LLC | 139,755 | $205.4K | 0.06% | +139,755 | New |
| Squarepoint Ops LLC | 135,338 | $198.9K | 0.00% | −180,692−57.2% | Reduced |
| Whitefort Capital Management, LP | 134,490 | $197.7K | 0.09% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 130,781 | $192.2K | 0.00% | −4,191−3.1% | Reduced |
| Csenge Advisory Group | 117,000 | $172.0K | 0.01% | 00.0% | Unchanged |
| Highline Wealth Partners LLC | 116,680 | $171.5K | 0.06% | 00.0% | Unchanged |
| Van Eck Associates Corp | 106,784 | $157.0K | 0.00% | −597−0.6% | Reduced |
| Comerica Bank | 106,369 | $156.4K | 0.00% | +16,369+18.2% | Added |
| Cambridge Investment Research Advisors, Inc. | 103,110 | $152.0K | 0.00% | −451−0.4% | Reduced |
| Arizona State Retirement System | 100,888 | $148.3K | 0.00% | +540+0.5% | Added |
| Phoenix Holdings Ltd. | 100,000 | $147.5K | 0.00% | 00.0% | Unchanged |
| Intrepid Capital Management Inc | 100,000 | $147.0K | 0.07% | 00.0% | Unchanged |
| Wolverine Trading, LLC | 97,722 | $143.7K | 0.00% | +27,570+39.3% | Added |
| Ameriprise Financial Inc | 94,391 | $138.8K | 0.00% | −5,500−5.5% | Reduced |
| ProShare Advisors LLC | 91,730 | $134.8K | 0.00% | +30,182+49.0% | Added |
| Hollencrest Capital Management | 90,000 | $132.3K | 0.01% | 00.0% | Unchanged |
| 360 Financial, Inc. | 80,800 | $118.8K | 0.04% | −100−0.1% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 77,449 | $113.8K | 0.00% | +77,449 | New |
| Two Sigma Securities, LLC | 75,782 | $111.4K | 0.02% | −38,430−33.6% | Reduced |
| KLP Kapitalforvaltning AS | 74,000 | $108.8K | 0.00% | +74,000 | New |
| Y-Intercept (Hong Kong) Ltd | 69,591 | $102.3K | 0.01% | +69,591 | New |
| Cascade Financial Partners, LLC | 66,490 | $97.7K | 0.01% | 00.0% | Unchanged |
| Brevan Howard Capital Management LP | 66,282 | $97.4K | 0.00% | −35,972−35.2% | Reduced |
| Pictet Asset Management Holding SA | 65,495 | $96.3K | 0.00% | 00.0% | Unchanged |
| Catalyst Funds Management Pty Ltd | 61,600 | $90.6K | 0.02% | +61,600 | New |
| Public Employees Retirement Association of Colorado | 61,502 | $90.0K | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 60,801 | $89.4K | 0.00% | 00.0% | Unchanged |
| Cetera Investment Advisers | 60,556 | $89.0K | 0.00% | −1,089−1.8% | Reduced |
| Kestra Private Wealth Services, LLC | 59,700 | $87.8K | 0.00% | +3,200+5.7% | Added |