Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q4 2022
Institutional positions in Opko Health, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 221
- 0 vs. Q3 2022
- Shares held
- 179.9M
- −5.08M (−2.7%) vs. Q3 2022
- Total value
- $224.8M
- −$124.8M (−35.7%) vs. Q3 2022
- New holders
- 33
- 64 more added
- Sold out
- 33
- 60 more reduced
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Vanguard Group Inc | 41,120,494 | $51.4M | 0.00% | +835,721+2.1% | Added |
| BlackRock Inc. | 35,476,921 | $44.3M | 0.00% | +968,918+2.8% | Added |
| State Street Corp | 10,445,318 | $13.1M | 0.00% | +71,045+0.7% | Added |
| Dimensional Fund Advisors LP | 8,956,810 | $11.2M | 0.00% | −1,866,831−17.2% | Reduced |
| Geode Capital Management, LLC | 7,987,366 | $9.98M | 0.00% | +158,178+2.0% | Added |
| D. E. Shaw & Co., Inc. | 5,786,177 | $7.23M | 0.01% | −182,129−3.1% | Reduced |
| Charles Schwab Investment Management Inc | 4,374,623 | $5.47M | 0.00% | +561,093+14.7% | Added |
| Northern Trust Corp | 3,853,292 | $4.82M | 0.00% | −52,062−1.3% | Reduced |
| Goldman Sachs Group Inc | 3,785,796 | $4.73M | 0.00% | +979,242+34.9% | Added |
| Millennium Management LLC | 3,720,447 | $4.65M | 0.01% | +1,578,263+73.7% | Added |
| Norges Bank | 3,233,385 | $4.04M | 0.00% | 00.0% | Unchanged |
| Oracle Investment Management Inc | 3,230,288 | $4.04M | 3.51% | −1,872,468−36.7% | Reduced |
| Nuveen Asset Management, LLC | 2,441,064 | $3.05M | 0.00% | +239,428+10.9% | Added |
| Deutsche Bank AG | 2,320,513 | $2.90M | 0.00% | +40,332+1.8% | Added |
| Renaissance Technologies LLC | 2,286,543 | $2.86M | 0.00% | −549,800−19.4% | Reduced |
| Two Sigma Investments, LP | 2,269,016 | $2.84M | 0.01% | −618,353−21.4% | Reduced |
| Two Sigma Advisers, LP | 2,262,997 | $2.83M | 0.01% | +140,600+6.6% | Added |
| Citigroup Inc | 2,132,483 | $2.67M | 0.00% | −9,909−0.5% | Reduced |
| Numerai GP LLC | 1,890,727 | $2.36M | 1.61% | +1,890,727 | New |
| Voya Investment Management LLC | 1,644,967 | $2.06M | 0.00% | +23,537+1.5% | Added |
| Bank of New York Mellon Corp | 1,540,406 | $1.93M | 0.00% | −502,924−24.6% | Reduced |
| JPMorgan Chase & Co | 1,278,818 | $1.60M | 0.00% | −1,095,358−46.1% | Reduced |
| Nordea Investment Management AB | 1,264,637 | $1.52M | 0.00% | −25,972−2.0% | Reduced |
| Swiss National Bank | 1,211,555 | $1.51M | 0.00% | +164,355+15.7% | Added |
| Bank of America Corp | 1,139,831 | $1.42M | 0.00% | +990,274+662.1% | Added |
| Morgan Stanley | 1,096,964 | $1.37M | 0.00% | −250,945−18.6% | Reduced |
| Citadel Advisors LLC | 1,075,629 | $1.34M | 0.00% | +225,421+26.5% | Added |
| Prudential Financial Inc | 1,007,691 | $1.26M | 0.00% | −41,900−4.0% | Reduced |
| AWM Investment Company, Inc. | 1,000,000 | $1.25M | 0.18% | +200,000+25.0% | Added |
| Graham Capital Management, L.P. | 824,029 | $1.03M | 0.04% | +373,391+82.9% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 818,624 | $1.02M | 0.01% | +61,384+8.1% | Added |
| Jupiter Asset Management Ltd | 765,198 | $948.8K | 0.01% | 00.0% | Unchanged |
| Invesco Ltd. | 728,808 | $911.0K | 0.00% | −2,643,321−78.4% | Reduced |
| Candriam Luxembourg S.C.A. | 654,601 | $818.2K | 0.01% | +202,253+44.7% | Added |
| Rhumbline Advisers | 643,379 | $804.0K | 0.00% | −5,327−0.8% | Reduced |
| Jane Street Group, LLC | 639,809 | $799.8K | 0.00% | −446,924−41.1% | Reduced |
| Alliancebernstein L.P. | 619,469 | $774.3K | 0.00% | +13,469+2.2% | Added |
| California State Teachers Retirement System | 596,995 | $746.2K | 0.00% | +56,418+10.4% | Added |
| Hennion & Walsh Asset Management, Inc. | 569,510 | $712.0K | 0.04% | +347,559+156.6% | Added |
| Credit Suisse AG | 541,024 | $676.3K | 0.00% | +131,742+32.2% | Added |
| Alps Advisors Inc | 524,592 | $655.7K | 0.01% | +103,188+24.5% | Added |
| State of Wisconsin Investment Board | 430,391 | $538.0K | 0.00% | −19,943−4.4% | Reduced |
| Commonwealth Equity Services, LLC | 403,977 | $504.0K | 0.00% | −3,630−0.9% | Reduced |
| Legal & General Group Plc | 398,975 | $498.7K | 0.00% | +22,632+6.0% | Added |
| Occudo Quantitative Strategies LP | 365,283 | $456.6K | 0.05% | +15,720+4.5% | Added |
| Price T Rowe Associates Inc | 357,797 | $447.0K | 0.00% | +85,739+31.5% | Added |
| Schonfeld Strategic Advisors LLC | 355,951 | $444.9K | 0.00% | −122,427−25.6% | Reduced |
| Tudor Investment Corp Et Al | 341,105 | $426.0K | 0.01% | 00.0% | Unchanged |
| UBS Asset Management Americas Inc | 334,071 | $417.6K | 0.00% | 00.0% | Unchanged |
| Engineers Gate Manager LP | 316,345 | $395.4K | 0.02% | +3,235+1.0% | Added |
| Royal Bank of Canada | 313,355 | $392.0K | 0.00% | +66,433+26.9% | Added |
| Susquehanna International Group, LLP | 267,377 | $334.2K | 0.00% | −968,580−78.4% | Reduced |
| New York State Common Retirement Fund | 261,700 | $327.1K | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 224,170 | $280.2K | 0.00% | +5,632+2.6% | Added |
| Qube Research & Technologies Ltd | 210,617 | $263.3K | 0.00% | +180,444+598.0% | Added |
| X-Square Capital, LLC | 204,321 | $256.0K | 0.15% | −1,075−0.5% | Reduced |
| Gamco Investors, Inc. Et Al | 200,000 | $250.0K | 0.00% | 00.0% | Unchanged |
| ETF Managers Group, LLC | 192,641 | $240.8K | 0.01% | −35,160−15.4% | Reduced |
| American International Group, Inc. | 190,980 | $238.7K | 0.00% | −695−0.4% | Reduced |
| Teton Advisors, Inc. | 190,000 | $237.5K | 0.06% | −20,000−9.5% | Reduced |
| Gabelli Funds LLC | 190,000 | $237.5K | 0.00% | −10,000−5.0% | Reduced |
| MetLife Investment Management | 183,333 | $229.2K | 0.00% | −31,048−14.5% | Reduced |
| Advisor Group Holdings, Inc. | 181,670 | $227.0K | 0.00% | +30,403+20.1% | Added |
| State Board of Administration of Florida Retirement System | 176,020 | $220.0K | 0.00% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 174,345 | $217.9K | 0.00% | +3,595+2.1% | Added |
| New York Life Investment Management LLC | 164,898 | $206.1K | 0.00% | +18,587+12.7% | Added |
| Capital Advisors Inc | 164,625 | $205.8K | 0.01% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 150,086 | $188.0K | 0.00% | +12,542+9.1% | Added |
| Phoenix Holdings Ltd. | 148,800 | $186.0K | 0.00% | −1,480,062−90.9% | Reduced |
| Van Eck Associates Corp | 144,164 | $180.0K | 0.00% | +2,229+1.6% | Added |
| Arizona State Retirement System | 141,589 | $177.0K | 0.00% | +21,219+17.6% | Added |
| Cambridge Investment Research Advisors, Inc. | 135,039 | $169.0K | 0.00% | −75,277−35.8% | Reduced |
| Csenge Advisory Group | 117,000 | $146.3K | 0.01% | 00.0% | Unchanged |
| Ameriprise Financial Inc | 116,879 | $146.0K | 0.00% | −14,400−11.0% | Reduced |
| Wilbanks Smith & Thomas Asset Management LLC | 108,450 | $135.6K | 0.01% | −27,526−20.2% | Reduced |
| Barclays PLC | 108,406 | $135.5K | 0.00% | +91,288+533.3% | Added |
| Principal Financial Group Inc | 107,860 | $134.8K | 0.00% | −95,707−47.0% | Reduced |
| Highline Wealth Partners LLC | 106,680 | $133.3K | 0.10% | 00.0% | Unchanged |
| Sequoia Financial Advisors, LLC | 103,971 | $130.0K | 0.00% | +103,971 | New |
| Virtu Financial LLC | 102,895 | $129.0K | 0.02% | +102,895 | New |
| Handelsbanken Fonder AB | 101,621 | $127.0K | 0.00% | 00.0% | Unchanged |
| Intrepid Capital Management Inc | 100,000 | $125.0K | 0.11% | 00.0% | Unchanged |
| Creative Planning | 98,033 | $122.5K | 0.00% | +3,336+3.5% | Added |
| Gsa Capital Partners LLP | 87,738 | $110.0K | 0.01% | +87,738 | New |
| Janus Henderson Group PLC | 87,852 | $109.4K | 0.00% | −90.0% | Reduced |
| Weiss Multi-Strategy Advisers LLC | 85,000 | $106.0K | 0.00% | 00.0% | Unchanged |
| Hollencrest Capital Management | 83,980 | $105.0K | 0.01% | 00.0% | Unchanged |
| Levin Capital Strategies, L.P. | 80,000 | $100.0K | 0.01% | +10,000+14.3% | Added |
| American Century Companies Inc | 79,917 | $99.9K | 0.00% | +27,616+52.8% | Added |
| State of Wyoming | 78,748 | $98.4K | 0.03% | +15,938+25.4% | Added |
| AQR Capital Management LLC | 78,338 | $97.9K | 0.00% | −252,911−76.4% | Reduced |
| AE Wealth Management LLC | 75,252 | $94.1K | 0.00% | −3,061−3.9% | Reduced |
| Wells Fargo & Company | 70,765 | $88.5K | 0.00% | −2,626−3.6% | Reduced |
| BDO Wealth Advisors, LLC | 70,000 | $87.5K | 0.01% | 00.0% | Unchanged |
| Shell Asset Management Co | 65,311 | $82.0K | 0.00% | −13,265−16.9% | Reduced |
| Pictet Asset Management SA | 65,495 | $82.0K | 0.00% | +30,895+89.3% | Added |
| Public Employees Retirement Association of Colorado | 61,502 | $77.0K | 0.00% | 00.0% | Unchanged |
| Raymond James Financial Services Advisors, Inc. | 61,380 | $76.7K | 0.00% | +3,010+5.2% | Added |
| Two Sigma Securities, LLC | 60,603 | $75.8K | 0.01% | +60,603 | New |
| 360 Financial, Inc. | 39,960 | $75.5K | 0.05% | 00.0% | Unchanged |