Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Opko Health, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 222
- −31 vs. Q1 2025
- Shares held
- 205.2M
- −36.9M (−15.2%) vs. Q1 2025
- Total value
- $270.4M
- −$130.9M (−32.6%) vs. Q1 2025
- New holders
- 17
- 56 more added
- Sold out
- 48
- 66 more reduced
2 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Rubric Capital Management LP | 47,791,243 | $63.1M | 1.01% | −915,397−1.9% | Reduced |
| Vanguard Group Inc | 38,238,714 | $50.5M | 0.00% | +8,738,643+29.6% | Added |
| BlackRock, Inc. | 31,449,482 | $41.5M | 0.00% | +3,844,508+13.9% | Added |
| Geode Capital Management, LLC | 10,424,473 | $13.8M | 0.00% | +1,995,633+23.7% | Added |
| State Street Corp | 8,581,840 | $11.3M | 0.00% | +442,344+5.4% | Added |
| UBS Group AG | 5,719,632 | $7.55M | 0.00% | +3,302,579+136.6% | Added |
| Weiss Asset Management LP | 4,756,992 | $6.28M | 0.10% | −6,435,808−57.5% | Reduced |
| Northern Trust Corp | 3,482,272 | $4.60M | 0.00% | −47,120−1.3% | Reduced |
| Charles Schwab Investment Management Inc | 3,350,376 | $4.42M | 0.00% | +608,390+22.2% | Added |
| Marshall Wace, LLP | 3,348,166 | $4.42M | 0.01% | −1,548,262−31.6% | Reduced |
| Goldman Sachs Group Inc | 2,820,055 | $3.72M | 0.00% | −1,181,159−29.5% | Reduced |
| Morgan Stanley | 2,059,054 | $2.72M | 0.00% | −2,049,434−49.9% | Reduced |
| AWM Investment Company, Inc. | 2,000,000 | $2.64M | 0.30% | +150,000+8.1% | Added |
| Dimensional Fund Advisors LP | 1,929,683 | $2.55M | 0.00% | −292,829−13.2% | Reduced |
| Graham Capital Management, L.P. | 1,911,131 | $2.52M | 0.08% | +100,739+5.6% | Added |
| Bank of America Corp | 1,906,839 | $2.52M | 0.00% | −2,252,043−54.2% | Reduced |
| Two Sigma Investments, LP | 1,836,747 | $2.42M | 0.00% | +190,972+11.6% | Added |
| Whitefort Capital Management, LP | 1,774,200 | $2.34M | 0.91% | +1,774,200 | New |
| Y.D. More Investments Ltd | 1,528,899 | $2.01M | 0.14% | −244,048−13.8% | Reduced |
| Jane Street Group, LLC | 1,384,552 | $1.83M | 0.00% | +835,214+152.0% | Added |
| Invesco Ltd. | 1,371,045 | $1.81M | 0.00% | −252,555−15.6% | Reduced |
| Washington Growth Strategies LLC | 1,356,124 | $1.79M | 1.37% | +1,356,122+67,806,100.0% | Added |
| Voya Investment Management LLC | 1,319,561 | $1.74M | 0.00% | +509,685+62.9% | Added |
| PFG Investments, LLC | 1,265,125 | $1.67M | 0.10% | +47,765+3.9% | Added |
| Bank of New York Mellon Corp | 1,148,906 | $1.52M | 0.00% | +128,385+12.6% | Added |
| UBS Asset Management Americas Inc | 1,127,476 | $1.49M | 0.00% | +345,842+44.2% | Added |
| Nuveen, LLC | 1,126,557 | $1.49M | 0.00% | −250,324−18.2% | Reduced |
| Tejara Capital Ltd | 946,090 | $1.25M | 0.58% | +85,746+10.0% | Added |
| AQR Capital Management LLC | 935,900 | $1.24M | 0.00% | −673,006−41.8% | Reduced |
| Assenagon Asset Management S.A. | 935,100 | $1.23M | 0.00% | 00.0% | Unchanged |
| Clearstead Advisors, LLC | 883,042 | $1.17M | 0.02% | 00.0% | Unchanged |
| Millennium Management LLC | 695,780 | $918.4K | 0.00% | −5,691,131−89.1% | Reduced |
| Barclays PLC | 664,407 | $877.0K | 0.00% | +272,416+69.5% | Added |
| Two Sigma Advisers, LP | 648,297 | $855.8K | 0.00% | +96,600+17.5% | Added |
| Susquehanna International Group, LLP | 644,670 | $851.0K | 0.00% | −111,476−14.7% | Reduced |
| JPMorgan Chase & Co | 630,355 | $832.1K | 0.00% | −1,870,977−74.8% | Reduced |
| BNP Paribas Arbitrage, SA | 581,671 | $767.8K | 0.00% | −309,474−34.7% | Reduced |
| Swiss National Bank | 577,355 | $762.1K | 0.00% | −83,800−12.7% | Reduced |
| Commonwealth Equity Services, LLC | 554,398 | $732.0K | 0.00% | +74,568+15.5% | Added |
| Rhumbline Advisers | 529,553 | $699.0K | 0.00% | +39,274+8.0% | Added |
| Alliancebernstein L.P. | 468,290 | $618.1K | 0.00% | −36,100−7.2% | Reduced |
| Price T Rowe Associates Inc | 437,506 | $578.0K | 0.00% | −64,162−12.8% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 391,664 | $517.0K | 0.00% | +190,319+94.5% | Added |
| Legal & General Group Plc | 355,682 | $469.5K | 0.00% | +5,584+1.6% | Added |
| California State Teachers Retirement System | 324,117 | $427.8K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 271,094 | $357.8K | 0.00% | +41,079+17.9% | Added |
| Royal Bank of Canada | 267,448 | $352.0K | 0.00% | +30,839+13.0% | Added |
| Tudor Investment Corp Et Al | 244,821 | $323.2K | 0.00% | 00.0% | Unchanged |
| Deutsche Bank AG | 239,018 | $315.5K | 0.00% | −42,629−15.1% | Reduced |
| MetLife Investment Management | 218,272 | $288.1K | 0.00% | +54,042+32.9% | Added |
| Citadel Advisors LLC | 217,395 | $287.0K | 0.00% | −1,639,131−88.3% | Reduced |
| Zazove Associates LLC | 207,600 | $274.0K | 0.02% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 206,375 | $272.0K | 0.00% | −145,901−41.4% | Reduced |
| Janus Henderson Group PLC | 206,314 | $271.3K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global ETFs Holdings Ltd. | 198,148 | $261.6K | 0.00% | +8,954+4.7% | Added |
| State Board of Administration of Florida Retirement System | 176,260 | $232.7K | 0.00% | 00.0% | Unchanged |
| Gamco Investors, Inc. Et Al | 175,000 | $231.0K | 0.00% | 00.0% | Unchanged |
| Gabelli Funds LLC | 170,000 | $224.4K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 167,111 | $220.6K | 0.00% | −96,790−36.7% | Reduced |
| Teton Advisors, Inc. | 142,000 | $187.4K | 0.11% | −2,500−1.7% | Reduced |
| Intech Investment Management LLC | 141,624 | $186.9K | 0.00% | −62,693−30.7% | Reduced |
| Manufacturers Life Insurance Company, The | 138,643 | $183.0K | 0.00% | +13,912+11.2% | Added |
| Cubist Systematic Strategies, LLC | 133,659 | $176.4K | 0.00% | +14,436+12.1% | Added |
| Csenge Advisory Group | 117,000 | $159.1K | 0.01% | 00.0% | Unchanged |
| Van Eck Associates Corp | 119,041 | $157.0K | 0.00% | +5,535+4.9% | Added |
| Highline Wealth Partners LLC | 116,680 | $154.0K | 0.05% | 00.0% | Unchanged |
| Glenmede Investment Management, LP | 112,750 | $148.8K | 0.00% | +112,750 | New |
| Comerica Bank | 112,000 | $147.8K | 0.00% | 00.0% | Unchanged |
| Humankind Investments LLC | 109,299 | $144.3K | 0.04% | +62,886+135.5% | Added |
| Ieq Capital, LLC | 109,219 | $144.2K | 0.00% | −74,144−40.4% | Reduced |
| Cambridge Investment Research Advisors, Inc. | 103,111 | $136.0K | 0.00% | +10.0% | Added |
| Phoenix Holdings Ltd. | 100,000 | $132.9K | 0.00% | 00.0% | Unchanged |
| Intrepid Capital Management Inc | 100,000 | $132.0K | 0.05% | 00.0% | Unchanged |
| Ameriprise Financial Inc | 94,760 | $125.1K | 0.00% | +669+0.7% | Added |
| Advisor Group Holdings, Inc. | 94,476 | $124.7K | 0.00% | −557,333−85.5% | Reduced |
| Squarepoint Ops LLC | 92,434 | $122.0K | 0.00% | −209,427−69.4% | Reduced |
| Hollencrest Capital Management | 90,000 | $118.8K | 0.01% | 00.0% | Unchanged |
| 360 Financial, Inc. | 88,800 | $117.2K | 0.04% | +9,500+12.0% | Added |
| Arizona State Retirement System | 88,194 | $116.4K | 0.00% | −9,689−9.9% | Reduced |
| XTX Topco Ltd | 84,907 | $112.1K | 0.00% | −224,383−72.5% | Reduced |
| State of Wyoming | 82,007 | $108.2K | 0.01% | +82,007 | New |
| Police & Firemen's Retirement System of New Jersey | 77,449 | $102.2K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 74,184 | $97.9K | 0.00% | +5,139+7.4% | Added |
| KLP Kapitalforvaltning AS | 74,000 | $97.7K | 0.00% | 00.0% | Unchanged |
| SIH Partners, LLLP | 69,419 | $91.6K | 0.01% | +69,419 | New |
| Cascade Financial Partners, LLC | 66,490 | $87.8K | 0.01% | 00.0% | Unchanged |
| Raymond James Financial Inc | 66,170 | $87.3K | 0.00% | −19,200−22.5% | Reduced |
| Pictet Asset Management Holding SA | 65,495 | $86.5K | 0.00% | 00.0% | Unchanged |
| Public Employees Retirement Association of Colorado | 61,502 | $81.0K | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 60,801 | $80.3K | 0.00% | 00.0% | Unchanged |
| Cetera Investment Advisers | 60,557 | $79.9K | 0.00% | +10.0% | Added |
| Kestra Private Wealth Services, LLC | 58,450 | $77.2K | 0.00% | 00.0% | Unchanged |
| Headlands Technologies LLC | 57,724 | $76.2K | 0.01% | +5,575+10.7% | Added |
| The PNC Financial Services Group, Inc. | 56,800 | $75.0K | 0.00% | 00.0% | Unchanged |
| Cim Investment Mangement Inc | 53,591 | $74.8K | 0.01% | +26,894+100.7% | Added |
| Private Advisor Group, LLC | 55,301 | $73.0K | 0.00% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 55,140 | $72.8K | 0.00% | 00.0% | Unchanged |
| Engineers Gate Manager LP | 55,124 | $72.8K | 0.00% | −161,233−74.5% | Reduced |
| Great West Life Assurance Co | 54,068 | $71.0K | 0.00% | 00.0% | Unchanged |
| First Manhattan Co | 51,750 | $68.3K | 0.00% | 00.0% | Unchanged |