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Opko Health, Inc.

OPK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000944809

No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Opko Health, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
222
−31 vs. Q1 2025
Shares held
205.2M
−36.9M (−15.2%) vs. Q1 2025
Total value
$270.4M
−$130.9M (−32.6%) vs. Q1 2025
New holders
17
56 more added
Sold out
48
66 more reduced

2 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 222 institutions
Q1 2021: 239 institutionsQ2 2021: 234 institutionsQ3 2021: 206 institutionsQ4 2021: 236 institutionsQ1 2022: 229 institutionsQ2 2022: 231 institutionsQ3 2022: 221 institutionsQ4 2022: 221 institutionsQ1 2023: 227 institutionsQ2 2023: 230 institutionsQ3 2023: 225 institutionsQ4 2023: 218 institutionsQ1 2024: 224 institutionsQ2 2024: 232 institutionsQ3 2024: 234 institutionsQ4 2024: 235 institutionsQ1 2025: 255 institutionsQ2 2025: 222 institutionsQ3 2025: 233 institutionsQ4 2025: 221 institutionsQ1 2026: 236 institutionsQ2 2026: 222 institutions
Value heldQ2 2025: $270.4M
Q1 2021: $817.1MQ2 2021: $773.3MQ3 2021: $668.9MQ4 2021: $914.8MQ1 2022: $671.0MQ2 2022: $479.9MQ3 2022: $349.6MQ4 2022: $224.8MQ1 2023: $259.3MQ2 2023: $375.6MQ3 2023: $267.6MQ4 2023: $256.6MQ1 2024: $190.7MQ2 2024: $227.7MQ3 2024: $278.1MQ4 2024: $290.3MQ1 2025: $401.4MQ2 2025: $270.4MQ3 2025: $303.6MQ4 2025: $251.1MQ1 2026: $229.4MQ2 2026: $303.4M
Institutions holding OPK and their total value by quarter
QuarterHoldersValue
Q2 2026222$303.4M
Q1 2026236$229.4M
Q4 2025221$251.1M
Q3 2025233$303.6M
Q2 2025222$270.4M
Q1 2025255$401.4M
Q4 2024235$290.3M
Q3 2024234$278.1M
Q2 2024232$227.7M
Q1 2024224$190.7M
Q4 2023218$256.6M
Q3 2023225$267.6M
Q2 2023230$375.6M
Q1 2023227$259.3M
Q4 2022221$224.8M
Q3 2022221$349.6M
Q2 2022231$479.9M
Q1 2022229$671.0M
Q4 2021236$914.8M
Q3 2021206$668.9M
Q2 2021234$773.3M
Q1 2021239$817.1M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q1 2025.

Institutions holding OPK in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Teacher Retirement System of Texas51,277$67.7K0.00%−32,489−38.8%Reduced
Transcend Wealth Collective, LLC50,851$67.1K0.01%+10.0%Added
Verition Fund Management LLC50,650$66.9K0.00%−267,296−84.1%Reduced
Farmers National Bank50,300$66.4K0.02%00.0%Unchanged
Prudential Financial Inc46,842$61.8K0.00%+20,076+75.0%Added
CIBC World Markets Corp44,575$58.8K0.00%−26,194−37.0%Reduced
Atom Investors LP43,282$57.1K0.01%+2,522+6.2%Added
Captrust Financial Advisors41,927$55.3K0.00%−6,555−13.5%Reduced
Victory Capital Management Inc41,761$55.1K0.00%+5,145+14.1%Added
Pensionmark Financial Group, LLC40,618$53.6K0.00%00.0%Unchanged
RK Asset Management, LLC40,485$53.0K0.05%00.0%Unchanged
Mercer Global Advisors Inc39,534$52.2K0.00%−15,423−28.1%Reduced
Norges Bank39,477$52.1K0.00%−454,780−92.0%Reduced
Brighton Jones LLC38,916$51.4K0.00%+8,775+29.1%Added
HighTower Advisors, LLC38,906$51.4K0.00%00.0%Unchanged
Kestra Advisory Services, LLC38,807$51.2K0.00%−11,500−22.9%Reduced
Wealth Enhancement Advisory Services, LLC36,994$50.3K0.00%−37,712−50.5%Reduced
Renaissance Technologies LLC38,100$50.3K0.00%+38,100New
Shell Asset Management Co37,028$49.0K0.00%−3,969−9.7%Reduced
HSBC Holdings PLC34,939$46.3K0.00%−1,913−5.2%Reduced
RSM US Wealth Management LLC33,757$44.6K0.00%00.0%Unchanged
Norris Perne & French LLP32,000$42.2K0.00%00.0%Unchanged
Operose Advisors LLC32,000$42.2K0.01%00.0%Unchanged
STRS Ohio31,900$42.1K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.31,889$42.1K0.00%00.0%Unchanged
Kapitalo Investimentos Ltda31,347$41.4K0.01%+31,347New
Tower Research Capital LLC (TRC)30,713$40.5K0.00%−11,737−27.6%Reduced
Fisher Asset Management, LLC30,301$40.0K0.00%+30,301New
Brinker Capital Investments, LLC30,000$39.6K0.00%00.0%Unchanged
IPG Investment Advisors LLC30,000$39.6K0.01%00.0%Unchanged
Diversify Wealth Management, LLC30,000$39.6K0.00%00.0%Unchanged
CIBC World Markets Inc.29,928$39.5K0.00%00.0%Unchanged
Capital Advisors Inc370,000$38.4K0.00%+20,000+5.7%Added
Equitable Holdings, Inc.28,931$38.2K0.00%00.0%Unchanged
EP Wealth Advisors, LLC28,900$38.1K0.00%−338−1.2%Reduced
Xponance, Inc.27,949$36.9K0.00%+4,191+17.6%Added
PBMares Wealth Management LLC27,021$35.7K0.01%00.0%Unchanged
Mackenzie Financial Corp25,843$34.1K0.00%00.0%Unchanged
SlateStone Wealth, LLC25,770$34.0K0.00%00.0%Unchanged
Principal Financial Group Inc24,773$32.7K0.00%+3,648+17.3%Added
Creative Planning24,492$32.3K0.00%−3,605−12.8%Reduced
Moseley Investment Management Inc24,153$31.9K0.01%00.0%Unchanged
Mariner, LLC24,092$31.8K0.00%+6,629+38.0%Added
CWM, LLC22,590$30.0K0.00%−51,913−69.7%Reduced
Altshuler Shaham Ltd22,471$29.6K0.00%−1,431,750−98.5%Reduced
CIBC Asset Management Inc21,918$28.9K0.00%00.0%Unchanged
Shufro Rose & Co LLC17,000$28.2K0.00%00.0%Unchanged
X-Square Capital, LLC21,040$28.0K0.01%−439,385−95.4%Reduced
State of Wisconsin Investment Board21,193$28.0K0.00%−8,577−28.8%Reduced
LPL Financial LLC20,236$26.7K0.00%−97−0.5%Reduced
Sax Wealth Advisors, LLC20,160$26.6K0.00%+50+0.2%Added
Sovereign Financial Group, Inc.20,078$26.5K0.01%−60.0%Reduced
Cumberland Advisors Inc19,500$25.7K0.01%00.0%Unchanged
Formidable Asset Management, LLC15,046$25.0K0.00%00.0%Unchanged
Sigma Planning Corp17,972$23.7K0.00%00.0%Unchanged
Stifel Financial Corp16,689$22.0K0.00%−160−0.9%Reduced
Westmount Partners, LLC16,550$21.8K0.01%00.0%Unchanged
Commons Capital, LLC16,300$21.5K0.02%00.0%Unchanged
FMR LLC16,121$21.3K0.00%−8,267−33.9%Reduced
Kovack Advisors, Inc.15,000$19.8K0.00%+5,000+50.0%Added
Colony Family Offices, LLC14,729$19.4K0.01%00.0%Unchanged
Integrated Wealth Concepts LLC14,322$18.9K0.00%+14,322New
Sanctuary Advisors, LLC14,040$18.5K0.00%−151−1.1%Reduced
Jones Financial Companies LLLP13,275$17.5K0.00%+1,650+14.2%Added
Mill Creek Capital Advisors, LLC12,383$16.3K0.00%+12,383New
Farther Finance Advisors, LLC12,219$16.1K0.00%00.0%Unchanged
Janney Montgomery Scott LLC12,500$16.0K0.00%+12,500New
Traphagen Investment Advisors LLC11,680$15.4K0.00%00.0%Unchanged
Stillwater Capital Advisors, LLC11,380$15.0K0.00%00.0%Unchanged
Amalgamated Bank11,110$15.0K0.00%00.0%Unchanged
Capital Square, LLC11,000$14.8K0.01%00.0%Unchanged
HBK Sorce Advisory LLC11,057$14.6K0.00%−352−3.1%Reduced
Key Financial Inc11,000$14.5K0.00%00.0%Unchanged
SEI Investments Co10,163$13.4K0.00%00.0%Unchanged
Diversified Trust Co10,000$13.2K0.00%−914−8.4%Reduced
KLCM Advisors, Inc.10,000$13.2K0.00%00.0%Unchanged
MRP Capital Investments, LLC10,000$13.2K0.01%00.0%Unchanged
Greenbush Financial Group, LLC10,000$13.2K0.01%00.0%Unchanged
Simplicity Wealth,LLC10,000$13.2K0.00%+10,000New
Sterling Capital Management LLC9,768$12.9K0.00%+4,265+77.5%Added
Aventura Private Wealth, LLC8,400$11.1K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC7,140$9.43K0.00%−3,094−30.2%Reduced
Raiffeisen Bank International AG6,521$8.61K0.00%00.0%Unchanged
National Bank of Canada4,922$6.43K0.00%−675−12.1%Reduced
Nisa Investment Advisors, LLC4,303$5.68K0.00%−160−3.6%Reduced
FSA Wealth Management LLC3,950$5.21K0.00%00.0%Unchanged
BNP PARIBAS ASSET MANAGEMENT Holding S.A.3,777$5.00K0.00%+3,777New
Aster Capital Management (DIFC) Ltd3,453$4.56K0.00%−15,809−82.1%Reduced
Larson Financial Group LLC3,040$4.01K0.00%+3,000+7,500.0%Added
Gables Capital Management Inc.3,000$3.96K0.00%00.0%Unchanged
EverSource Wealth Advisors, LLC2,677$3.53K0.00%+397+17.4%Added
Moser Wealth Advisors, LLC2,392$3.16K0.00%00.0%Unchanged
Allworth Financial LP1,813$2.39K0.00%+190+11.7%Added
CoreCap Advisors, LLC1,600$2.11K0.00%−134−7.7%Reduced
PFS Partners, LLC1,100$1.45K0.00%00.0%Unchanged
Essential Partners LLC1,024$1.35K0.00%+1,024New
MAI Capital Management1,000$1.32K0.00%00.0%Unchanged
Salomon & Ludwin, LLC976$1.31K0.00%−19−1.9%Reduced
Transce3nd, LLC900$1.19K0.00%00.0%Unchanged
CBIZ Investment Advisory Services, LLC698$9210.00%00.0%Unchanged