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Opko Health, Inc.

OPK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000944809

No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Opko Health, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
222
−31 vs. Q1 2025
Shares held
205.2M
−36.9M (−15.2%) vs. Q1 2025
Total value
$270.4M
−$130.9M (−32.6%) vs. Q1 2025
New holders
17
56 more added
Sold out
48
66 more reduced

2 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 222 institutions
Q1 2021: 239 institutionsQ2 2021: 234 institutionsQ3 2021: 206 institutionsQ4 2021: 236 institutionsQ1 2022: 229 institutionsQ2 2022: 231 institutionsQ3 2022: 221 institutionsQ4 2022: 221 institutionsQ1 2023: 227 institutionsQ2 2023: 230 institutionsQ3 2023: 225 institutionsQ4 2023: 218 institutionsQ1 2024: 224 institutionsQ2 2024: 232 institutionsQ3 2024: 234 institutionsQ4 2024: 235 institutionsQ1 2025: 255 institutionsQ2 2025: 222 institutionsQ3 2025: 233 institutionsQ4 2025: 221 institutionsQ1 2026: 236 institutionsQ2 2026: 222 institutions
Value heldQ2 2025: $270.4M
Q1 2021: $817.1MQ2 2021: $773.3MQ3 2021: $668.9MQ4 2021: $914.8MQ1 2022: $671.0MQ2 2022: $479.9MQ3 2022: $349.6MQ4 2022: $224.8MQ1 2023: $259.3MQ2 2023: $375.6MQ3 2023: $267.6MQ4 2023: $256.6MQ1 2024: $190.7MQ2 2024: $227.7MQ3 2024: $278.1MQ4 2024: $290.3MQ1 2025: $401.4MQ2 2025: $270.4MQ3 2025: $303.6MQ4 2025: $251.1MQ1 2026: $229.4MQ2 2026: $303.4M
Institutions holding OPK and their total value by quarter
QuarterHoldersValue
Q2 2026222$303.4M
Q1 2026236$229.4M
Q4 2025221$251.1M
Q3 2025233$303.6M
Q2 2025222$270.4M
Q1 2025255$401.4M
Q4 2024235$290.3M
Q3 2024234$278.1M
Q2 2024232$227.7M
Q1 2024224$190.7M
Q4 2023218$256.6M
Q3 2023225$267.6M
Q2 2023230$375.6M
Q1 2023227$259.3M
Q4 2022221$224.8M
Q3 2022221$349.6M
Q2 2022231$479.9M
Q1 2022229$671.0M
Q4 2021236$914.8M
Q3 2021206$668.9M
Q2 2021234$773.3M
Q1 2021239$817.1M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q1 2025.

Institutions holding OPK in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Bessemer Group Inc273$00.00%00.0%Unchanged
Centerpoint Advisors, LLC100$00.00%00.0%Unchanged
Covestor Ltd183$00.00%+96+110.3%Added
GWM Advisors LLC1$10.00%−18−94.7%Reduced
LRI Investments, LLC1$10.00%00.0%Unchanged
Crewe Advisors LLC1$20.00%+1New
Darwin Advisors, LLC5$60.00%00.0%Unchanged
True Wealth Design, LLC13$180.00%−767−98.3%Reduced
Boreal Capital Management LLC69$910.00%+69New
SBI Securities Co., Ltd.92$1210.00%−1−1.1%Reduced
Salem Investment Counselors Inc100$1320.00%00.0%Unchanged
Harbor Investment Advisory, LLC180$2380.00%00.0%Unchanged
Global Retirement Partners, LLC200$2640.00%+200New
Medallion Wealth Advisors, LLC200$2660.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co227$3000.00%00.0%Unchanged
Pittenger & Anderson Inc250$3300.00%00.0%Unchanged
Rothschild Investment LLC400$5280.00%+200+100.0%Added
IFP Advisors, Inc439$5790.00%+336+326.2%Added
UMA Financial Services, Inc.470$6210.00%+470New
Smartleaf Asset Management LLC474$6250.00%00.0%Unchanged
US Bancorp600$7920.00%−828−58.0%Reduced
Russell Investments Group, Ltd.620$8180.00%00.0%Unchanged
CBIZ Investment Advisory Services, LLC698$9210.00%00.0%Unchanged
Transce3nd, LLC900$1.19K0.00%00.0%Unchanged
Salomon & Ludwin, LLC976$1.31K0.00%−19−1.9%Reduced
MAI Capital Management1,000$1.32K0.00%00.0%Unchanged
Essential Partners LLC1,024$1.35K0.00%+1,024New
PFS Partners, LLC1,100$1.45K0.00%00.0%Unchanged
CoreCap Advisors, LLC1,600$2.11K0.00%−134−7.7%Reduced
Allworth Financial LP1,813$2.39K0.00%+190+11.7%Added
Moser Wealth Advisors, LLC2,392$3.16K0.00%00.0%Unchanged
EverSource Wealth Advisors, LLC2,677$3.53K0.00%+397+17.4%Added
Gables Capital Management Inc.3,000$3.96K0.00%00.0%Unchanged
Larson Financial Group LLC3,040$4.01K0.00%+3,000+7,500.0%Added
Aster Capital Management (DIFC) Ltd3,453$4.56K0.00%−15,809−82.1%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.3,777$5.00K0.00%+3,777New
FSA Wealth Management LLC3,950$5.21K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC4,303$5.68K0.00%−160−3.6%Reduced
National Bank of Canada4,922$6.43K0.00%−675−12.1%Reduced
Raiffeisen Bank International AG6,521$8.61K0.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC7,140$9.43K0.00%−3,094−30.2%Reduced
Aventura Private Wealth, LLC8,400$11.1K0.00%00.0%Unchanged
Sterling Capital Management LLC9,768$12.9K0.00%+4,265+77.5%Added
Diversified Trust Co10,000$13.2K0.00%−914−8.4%Reduced
KLCM Advisors, Inc.10,000$13.2K0.00%00.0%Unchanged
MRP Capital Investments, LLC10,000$13.2K0.01%00.0%Unchanged
Greenbush Financial Group, LLC10,000$13.2K0.01%00.0%Unchanged
Simplicity Wealth,LLC10,000$13.2K0.00%+10,000New
SEI Investments Co10,163$13.4K0.00%00.0%Unchanged
Key Financial Inc11,000$14.5K0.00%00.0%Unchanged
HBK Sorce Advisory LLC11,057$14.6K0.00%−352−3.1%Reduced
Capital Square, LLC11,000$14.8K0.01%00.0%Unchanged
Amalgamated Bank11,110$15.0K0.00%00.0%Unchanged
Stillwater Capital Advisors, LLC11,380$15.0K0.00%00.0%Unchanged
Traphagen Investment Advisors LLC11,680$15.4K0.00%00.0%Unchanged
Janney Montgomery Scott LLC12,500$16.0K0.00%+12,500New
Farther Finance Advisors, LLC12,219$16.1K0.00%00.0%Unchanged
Mill Creek Capital Advisors, LLC12,383$16.3K0.00%+12,383New
Jones Financial Companies LLLP13,275$17.5K0.00%+1,650+14.2%Added
Sanctuary Advisors, LLC14,040$18.5K0.00%−151−1.1%Reduced
Integrated Wealth Concepts LLC14,322$18.9K0.00%+14,322New
Colony Family Offices, LLC14,729$19.4K0.01%00.0%Unchanged
Kovack Advisors, Inc.15,000$19.8K0.00%+5,000+50.0%Added
FMR LLC16,121$21.3K0.00%−8,267−33.9%Reduced
Commons Capital, LLC16,300$21.5K0.02%00.0%Unchanged
Westmount Partners, LLC16,550$21.8K0.01%00.0%Unchanged
Stifel Financial Corp16,689$22.0K0.00%−160−0.9%Reduced
Sigma Planning Corp17,972$23.7K0.00%00.0%Unchanged
Formidable Asset Management, LLC15,046$25.0K0.00%00.0%Unchanged
Cumberland Advisors Inc19,500$25.7K0.01%00.0%Unchanged
Sovereign Financial Group, Inc.20,078$26.5K0.01%−60.0%Reduced
Sax Wealth Advisors, LLC20,160$26.6K0.00%+50+0.2%Added
LPL Financial LLC20,236$26.7K0.00%−97−0.5%Reduced
State of Wisconsin Investment Board21,193$28.0K0.00%−8,577−28.8%Reduced
X-Square Capital, LLC21,040$28.0K0.01%−439,385−95.4%Reduced
Shufro Rose & Co LLC17,000$28.2K0.00%00.0%Unchanged
CIBC Asset Management Inc21,918$28.9K0.00%00.0%Unchanged
Altshuler Shaham Ltd22,471$29.6K0.00%−1,431,750−98.5%Reduced
CWM, LLC22,590$30.0K0.00%−51,913−69.7%Reduced
Mariner, LLC24,092$31.8K0.00%+6,629+38.0%Added
Moseley Investment Management Inc24,153$31.9K0.01%00.0%Unchanged
Creative Planning24,492$32.3K0.00%−3,605−12.8%Reduced
Principal Financial Group Inc24,773$32.7K0.00%+3,648+17.3%Added
SlateStone Wealth, LLC25,770$34.0K0.00%00.0%Unchanged
Mackenzie Financial Corp25,843$34.1K0.00%00.0%Unchanged
PBMares Wealth Management LLC27,021$35.7K0.01%00.0%Unchanged
Xponance, Inc.27,949$36.9K0.00%+4,191+17.6%Added
EP Wealth Advisors, LLC28,900$38.1K0.00%−338−1.2%Reduced
Equitable Holdings, Inc.28,931$38.2K0.00%00.0%Unchanged
Capital Advisors Inc370,000$38.4K0.00%+20,000+5.7%Added
CIBC World Markets Inc.29,928$39.5K0.00%00.0%Unchanged
Brinker Capital Investments, LLC30,000$39.6K0.00%00.0%Unchanged
IPG Investment Advisors LLC30,000$39.6K0.01%00.0%Unchanged
Diversify Wealth Management, LLC30,000$39.6K0.00%00.0%Unchanged
Fisher Asset Management, LLC30,301$40.0K0.00%+30,301New
Tower Research Capital LLC (TRC)30,713$40.5K0.00%−11,737−27.6%Reduced
Kapitalo Investimentos Ltda31,347$41.4K0.01%+31,347New
Ameritas Investment Partners, Inc.31,889$42.1K0.00%00.0%Unchanged
STRS Ohio31,900$42.1K0.00%00.0%Unchanged
Norris Perne & French LLP32,000$42.2K0.00%00.0%Unchanged