Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q1 2023
Institutional positions in Opko Health, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 227
- +9 vs. Q4 2022
- Shares held
- 177.7M
- −2.15M (−1.2%) vs. Q4 2022
- Total value
- $259.3M
- +$34.5M (+15.4%) vs. Q4 2022
- New holders
- 32
- 59 more added
- Sold out
- 23
- 56 more reduced
3 institutions that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q1 2023
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q4 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Vanguard Group Inc | 41,554,932 | $60.7M | 0.00% | +434,438+1.1% | Added |
| BlackRock Inc. | 34,966,193 | $51.1M | 0.00% | −510,728−1.4% | Reduced |
| State Street Corp | 10,502,375 | $15.3M | 0.00% | +57,057+0.5% | Added |
| Geode Capital Management, LLC | 8,410,646 | $12.3M | 0.00% | +423,280+5.3% | Added |
| Dimensional Fund Advisors LP | 6,880,047 | $10.0M | 0.00% | −2,076,763−23.2% | Reduced |
| Millennium Management LLC | 6,421,832 | $9.38M | 0.01% | +2,701,385+72.6% | Added |
| D. E. Shaw & Co., Inc. | 5,271,971 | $7.70M | 0.01% | −514,206−8.9% | Reduced |
| Charles Schwab Investment Management Inc | 4,847,740 | $7.08M | 0.00% | +473,117+10.8% | Added |
| Northern Trust Corp | 3,884,100 | $5.67M | 0.00% | +30,808+0.8% | Added |
| Norges Bank | 3,233,385 | $4.72M | 0.00% | 00.0% | Unchanged |
| Oracle Investment Management Inc | 2,843,165 | $4.15M | 4.09% | −387,123−12.0% | Reduced |
| Nuveen Asset Management, LLC | 2,678,175 | $3.91M | 0.00% | +237,111+9.7% | Added |
| Goldman Sachs Group Inc | 2,403,846 | $3.51M | 0.00% | −1,381,950−36.5% | Reduced |
| Numerai GP LLC | 2,208,295 | $3.22M | 1.08% | +317,568+16.8% | Added |
| Two Sigma Investments, LP | 1,924,474 | $2.81M | 0.01% | −344,542−15.2% | Reduced |
| Two Sigma Advisers, LP | 1,797,297 | $2.62M | 0.01% | −465,700−20.6% | Reduced |
| Deutsche Bank AG | 1,738,310 | $2.54M | 0.00% | −582,203−25.1% | Reduced |
| Renaissance Technologies LLC | 1,688,143 | $2.46M | 0.00% | −598,400−26.2% | Reduced |
| Voya Investment Management LLC | 1,553,399 | $2.27M | 0.00% | −91,568−5.6% | Reduced |
| Bank of New York Mellon Corp | 1,542,043 | $2.25M | 0.00% | +1,637+0.1% | Added |
| Citigroup Inc | 1,498,947 | $2.19M | 0.00% | −633,536−29.7% | Reduced |
| Morgan Stanley | 1,384,991 | $2.02M | 0.00% | +288,027+26.3% | Added |
| Invesco Ltd. | 1,264,924 | $1.85M | 0.00% | +536,116+73.6% | Added |
| JPMorgan Chase & Co | 1,265,200 | $1.85M | 0.00% | −13,618−1.1% | Reduced |
| Nordea Investment Management AB | 1,245,050 | $1.76M | 0.00% | −19,587−1.5% | Reduced |
| Assenagon Asset Management S.A. | 1,221,953 | $1.70M | 0.01% | +1,221,953 | New |
| Swiss National Bank | 1,083,955 | $1.58M | 0.00% | −127,600−10.5% | Reduced |
| AWM Investment Company, Inc. | 1,000,000 | $1.46M | 0.20% | 00.0% | Unchanged |
| Prudential Financial Inc | 893,941 | $1.31M | 0.00% | −113,750−11.3% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 890,430 | $1.30M | 0.01% | +71,806+8.8% | Added |
| Jupiter Asset Management Ltd | 765,198 | $1.11M | 0.02% | 00.0% | Unchanged |
| Rhumbline Advisers | 662,663 | $967.0K | 0.00% | +19,284+3.0% | Added |
| Hennion & Walsh Asset Management, Inc. | 626,250 | $914.0K | 0.06% | +56,740+10.0% | Added |
| Alliancebernstein L.P. | 619,469 | $904.4K | 0.00% | 00.0% | Unchanged |
| Graham Capital Management, L.P. | 612,288 | $893.9K | 0.03% | −211,741−25.7% | Reduced |
| Credit Suisse AG | 603,372 | $880.9K | 0.00% | +62,348+11.5% | Added |
| Intrinsic Edge Capital Management LLC | 600,000 | $876.0K | 0.09% | +600,000 | New |
| California State Teachers Retirement System | 591,323 | $863.3K | 0.00% | −5,672−1.0% | Reduced |
| Bank of America Corp | 581,883 | $849.5K | 0.00% | −557,948−49.0% | Reduced |
| Susquehanna International Group, LLP | 577,350 | $842.9K | 0.00% | +309,973+115.9% | Added |
| Alps Advisors Inc | 509,055 | $743.2K | 0.01% | −15,537−3.0% | Reduced |
| UBS Asset Management Americas Inc | 440,282 | $642.8K | 0.00% | +106,211+31.8% | Added |
| Legal & General Group Plc | 424,403 | $619.6K | 0.00% | +25,428+6.4% | Added |
| Price T Rowe Associates Inc | 405,029 | $592.0K | 0.00% | +47,232+13.2% | Added |
| Commonwealth Equity Services, LLC | 404,012 | $589.0K | 0.00% | +350.0% | Added |
| First Trust Advisors LP | 393,583 | $574.6K | 0.00% | +393,583 | New |
| State of Wisconsin Investment Board | 387,959 | $566.4K | 0.00% | −42,432−9.9% | Reduced |
| Occudo Quantitative Strategies LP | 347,583 | $507.5K | 0.05% | −17,700−4.8% | Reduced |
| Tudor Investment Corp Et Al | 339,891 | $496.0K | 0.01% | −1,214−0.4% | Reduced |
| UBS Group AG | 310,170 | $452.8K | 0.00% | +86,000+38.4% | Added |
| Engineers Gate Manager LP | 305,658 | $446.3K | 0.02% | −10,687−3.4% | Reduced |
| Citadel Advisors LLC | 264,227 | $385.8K | 0.00% | −811,402−75.4% | Reduced |
| ETF Managers Group, LLC | 256,528 | $374.5K | 0.01% | +63,887+33.2% | Added |
| MetLife Investment Management | 211,348 | $308.6K | 0.00% | +28,015+15.3% | Added |
| Royal Bank of Canada | 209,067 | $305.0K | 0.00% | −104,288−33.3% | Reduced |
| Janus Henderson Group PLC | 209,037 | $304.2K | 0.00% | +121,185+137.9% | Added |
| Barclays PLC | 205,070 | $299.4K | 0.00% | +96,664+89.2% | Added |
| Gamco Investors, Inc. Et Al | 200,000 | $292.0K | 0.00% | 00.0% | Unchanged |
| X-Square Capital, LLC | 199,432 | $291.0K | 0.17% | −4,889−2.4% | Reduced |
| New York State Common Retirement Fund | 196,400 | $286.7K | 0.00% | −65,300−25.0% | Reduced |
| BNP Paribas Arbitrage, SA | 195,868 | $286.0K | 0.00% | +152,183+348.4% | Added |
| American International Group, Inc. | 194,858 | $284.5K | 0.00% | +3,878+2.0% | Added |
| Gabelli Funds LLC | 190,000 | $277.4K | 0.00% | 00.0% | Unchanged |
| Teton Advisors, Inc. | 190,000 | $277.4K | 0.07% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 183,919 | $269.0K | 0.00% | +33,833+22.5% | Added |
| State Board of Administration of Florida Retirement System | 176,020 | $257.0K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 175,273 | $255.9K | 0.00% | +104,508+147.7% | Added |
| Manufacturers Life Insurance Company, The | 166,248 | $242.7K | 0.00% | −8,097−4.6% | Reduced |
| Capital Advisors Inc | 164,625 | $240.4K | 0.01% | 00.0% | Unchanged |
| Phoenix Holdings Ltd. | 148,800 | $217.2K | 0.00% | 00.0% | Unchanged |
| Arizona State Retirement System | 145,528 | $212.5K | 0.00% | +3,939+2.8% | Added |
| Advisor Group Holdings, Inc. | 143,170 | $209.2K | 0.00% | −38,500−21.2% | Reduced |
| Van Eck Associates Corp | 142,171 | $208.0K | 0.00% | −1,993−1.4% | Reduced |
| Group One Trading, L.P. | 139,725 | $204.0K | 0.01% | +139,725 | New |
| Verition Fund Management LLC | 138,600 | $202.4K | 0.00% | +138,600 | New |
| Cambridge Investment Research Advisors, Inc. | 131,974 | $193.0K | 0.00% | −3,065−2.3% | Reduced |
| Wilbanks Smith & Thomas Asset Management LLC | 131,380 | $191.8K | 0.01% | +22,930+21.1% | Added |
| Jane Street Group, LLC | 129,287 | $188.8K | 0.00% | −510,522−79.8% | Reduced |
| Levin Capital Strategies, L.P. | 125,000 | $182.5K | 0.02% | +45,000+56.3% | Added |
| Csenge Advisory Group | 117,000 | $170.8K | 0.01% | 00.0% | Unchanged |
| Simplex Trading, LLC | 113,893 | $166.0K | 0.01% | +113,893 | New |
| Quantbot Technologies LP | 111,476 | $162.8K | 0.01% | +66,984+150.6% | Added |
| Principal Financial Group Inc | 111,375 | $162.6K | 0.00% | +3,515+3.3% | Added |
| Ameriprise Financial Inc | 108,879 | $159.0K | 0.00% | −8,000−6.8% | Reduced |
| Highline Wealth Partners LLC | 106,680 | $155.8K | 0.11% | 00.0% | Unchanged |
| Handelsbanken Fonder AB | 101,621 | $148.0K | 0.00% | 00.0% | Unchanged |
| Creative Planning | 100,100 | $146.1K | 0.00% | +2,067+2.1% | Added |
| Intrepid Capital Management Inc | 100,000 | $146.0K | 0.13% | 00.0% | Unchanged |
| American Century Companies Inc | 98,556 | $137.0K | 0.00% | +18,639+23.3% | Added |
| Schonfeld Strategic Advisors LLC | 89,000 | $129.9K | 0.00% | −266,951−75.0% | Reduced |
| Cubist Systematic Strategies, LLC | 84,739 | $123.7K | 0.00% | +84,739 | New |
| Hollencrest Capital Management | 83,980 | $122.6K | 0.01% | 00.0% | Unchanged |
| AE Wealth Management LLC | 76,002 | $111.0K | 0.00% | +750+1.0% | Added |
| Sowell Financial Services LLC | 75,200 | $110.0K | 0.01% | +75,200 | New |
| State of Wyoming | 72,946 | $106.5K | 0.03% | −5,802−7.4% | Reduced |
| BDO Wealth Advisors, LLC | 70,000 | $102.2K | 0.01% | 00.0% | Unchanged |
| Pictet Asset Management SA | 65,495 | $95.6K | 0.00% | 00.0% | Unchanged |
| Shell Asset Management Co | 65,083 | $95.0K | 0.00% | −228−0.3% | Reduced |
| Public Employees Retirement Association of Colorado | 61,502 | $90.0K | 0.00% | 00.0% | Unchanged |
| Amundi | 60,662 | $88.6K | 0.00% | +60,662 | New |