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Opko Health, Inc.

OPK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000944809

No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.

13F holders, Q1 2024

Institutional positions in Opko Health, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
224
+8 vs. Q4 2023
Shares held
158.7M
−11.2M (−6.6%) vs. Q4 2023
Total value
$190.7M
−$65.8M (−25.7%) vs. Q4 2023
New holders
43
49 more added
Sold out
35
63 more reduced

2 institutions that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 224 institutions
Q1 2021: 239 institutionsQ2 2021: 234 institutionsQ3 2021: 206 institutionsQ4 2021: 236 institutionsQ1 2022: 229 institutionsQ2 2022: 231 institutionsQ3 2022: 221 institutionsQ4 2022: 221 institutionsQ1 2023: 227 institutionsQ2 2023: 230 institutionsQ3 2023: 225 institutionsQ4 2023: 218 institutionsQ1 2024: 224 institutionsQ2 2024: 232 institutionsQ3 2024: 234 institutionsQ4 2024: 235 institutionsQ1 2025: 255 institutionsQ2 2025: 222 institutionsQ3 2025: 233 institutionsQ4 2025: 221 institutionsQ1 2026: 236 institutionsQ2 2026: 222 institutions
Value heldQ1 2024: $190.7M
Q1 2021: $817.1MQ2 2021: $773.3MQ3 2021: $668.9MQ4 2021: $914.8MQ1 2022: $671.0MQ2 2022: $479.9MQ3 2022: $349.6MQ4 2022: $224.8MQ1 2023: $259.3MQ2 2023: $375.6MQ3 2023: $267.6MQ4 2023: $256.6MQ1 2024: $190.7MQ2 2024: $227.7MQ3 2024: $278.1MQ4 2024: $290.3MQ1 2025: $401.4MQ2 2025: $270.4MQ3 2025: $303.6MQ4 2025: $251.1MQ1 2026: $229.4MQ2 2026: $303.4M
Institutions holding OPK and their total value by quarter
QuarterHoldersValue
Q2 2026222$303.4M
Q1 2026236$229.4M
Q4 2025221$251.1M
Q3 2025233$303.6M
Q2 2025222$270.4M
Q1 2025255$401.4M
Q4 2024235$290.3M
Q3 2024234$278.1M
Q2 2024232$227.7M
Q1 2024224$190.7M
Q4 2023218$256.6M
Q3 2023225$267.6M
Q2 2023230$375.6M
Q1 2023227$259.3M
Q4 2022221$224.8M
Q3 2022221$349.6M
Q2 2022231$479.9M
Q1 2022229$671.0M
Q4 2021236$914.8M
Q3 2021206$668.9M
Q2 2021234$773.3M
Q1 2021239$817.1M

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q4 2023.

Institutions holding OPK in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock Inc.33,228,935$39.9M0.00%−3,736,494−10.1%Reduced
Vanguard Group Inc29,501,231$35.4M0.00%−10,250,062−25.8%Reduced
State Street Corp10,202,528$12.2M0.00%+895,844+9.6%Added
Geode Capital Management, LLC9,971,554$12.0M0.00%+252,186+2.6%Added
Charles Schwab Investment Management Inc5,809,298$6.97M0.00%+75,598+1.3%Added
Rubric Capital Management LP4,935,814$5.92M0.18%+4,935,814New
Northern Trust Corp4,771,226$5.73M0.00%−263,029−5.2%Reduced
Portolan Capital Management, LLC3,241,418$3.89M0.30%+1,579,652+95.1%Added
Goldman Sachs Group Inc3,116,991$3.74M0.00%+207,492+7.1%Added
Voya Investment Management LLC3,090,765$3.71M0.00%+1,349,194+77.5%Added
Dimensional Fund Advisors LP2,921,436$3.51M0.00%−527,626−15.3%Reduced
D. E. Shaw & Co., Inc.2,646,084$3.18M0.00%−3,196,453−54.7%Reduced
Norges Bank2,081,955$2.50M0.00%−621,127−23.0%Reduced
HRT Financial LP1,716,192$2.06M0.01%+1,372,587+399.5%Added
Two Sigma Investments, LP1,634,687$1.96M0.00%+665,872+68.7%Added
Allianz Asset Management GmbH1,606,046$1.93M0.00%+841,837+110.2%Added
JPMorgan Chase & Co1,592,553$1.91M0.00%−351,784−18.1%Reduced
Invesco Ltd.1,555,536$1.87M0.00%−3,938,740−71.7%Reduced
Citigroup Inc1,523,241$1.83M0.00%−26,341−1.7%Reduced
Bank of New York Mellon Corp1,467,375$1.76M0.00%−146,024−9.1%Reduced
Renaissance Technologies LLC1,378,196$1.65M0.00%+1,378,196New
Jane Street Group, LLC1,324,822$1.59M0.00%+966,678+269.9%Added
Morgan Stanley1,301,628$1.56M0.00%−568,715−30.4%Reduced
AWM Investment Company, Inc.1,300,000$1.56M0.20%+200,000+18.2%Added
Assenagon Asset Management S.A.1,253,808$1.50M0.00%+648,569+107.2%Added
Intrinsic Edge Capital Management LLC1,200,000$1.44M0.12%+200,000+20.0%Added
Two Sigma Advisers, LP1,192,797$1.43M0.00%+55,900+4.9%Added
Nuveen Asset Management, LLC1,049,637$1.26M0.00%−97,732−8.5%Reduced
UBS Group AG1,036,650$1.24M0.00%−376,650−26.7%Reduced
Credit Suisse AG937,395$1.12M0.00%+41,377+4.6%Added
PFG Investments, LLC937,265$1.12M0.07%+937,265New
Wilbanks Smith & Thomas Asset Management LLC878,824$1.05M0.03%+747,444+568.9%Added
Swiss National Bank837,855$1.01M0.00%00.0%Unchanged
Millennium Management LLC779,430$935.3K0.00%+182,986+30.7%Added
Hennion & Walsh Asset Management, Inc.776,020$931.2K0.05%+79,525+11.4%Added
Jupiter Asset Management Ltd765,198$918.2K0.01%00.0%Unchanged
Rhumbline Advisers667,426$800.9K0.00%+17,409+2.7%Added
Cantor Fitzgerald, L. P.425,412$718.7K0.17%+425,412New
Alliancebernstein L.P.570,109$684.1K0.00%00.0%Unchanged
Engineers Gate Manager LP492,047$590.5K0.02%+171,628+53.6%Added
Alps Advisors Inc491,610$589.9K0.00%−44,871−8.4%Reduced
Price T Rowe Associates Inc445,981$536.0K0.00%+17,671+4.1%Added
Barclays PLC444,112$532.9K0.00%−323,966−42.2%Reduced
Commonwealth Equity Services, LLC437,276$525.0K0.00%+24,350+5.9%Added
California State Teachers Retirement System422,677$507.2K0.00%−22,245−5.0%Reduced
Legal & General Group Plc418,602$502.3K0.00%00.0%Unchanged
UBS Asset Management Americas Inc401,189$481.4K0.00%00.0%Unchanged
Bank of America Corp394,819$473.8K0.00%−13,236−3.2%Reduced
First Trust Advisors LP368,160$441.8K0.00%+62,429+20.4%Added
BNP Paribas Arbitrage, SA336,315$403.6K0.00%+64,443+23.7%Added
Susquehanna International Group, LLP309,754$371.7K0.00%−186,643−37.6%Reduced
Simplex Trading, LLC273,551$328.0K0.01%+125,191+84.4%Added
Royal Bank of Canada262,507$314.0K0.00%−41,904−13.8%Reduced
Tudor Investment Corp Et Al244,821$293.8K0.00%00.0%Unchanged
Citadel Advisors LLC223,386$268.1K0.00%−185,165−45.3%Reduced
Lazard Asset Management LLC215,439$258.0K0.00%+215,439New
State Board of Administration of Florida Retirement System176,020$257.0K0.00%−240−0.1%Reduced
Janus Henderson Group PLC208,463$252.2K0.00%+140.0%Added
Wells Fargo & Company202,428$242.9K0.00%+16,623+8.9%Added
Toroso Investments, LLC198,940$238.7K0.00%+198,940New
American International Group, Inc.198,789$238.5K0.00%−1,707−0.9%Reduced
Deutsche Bank AG196,768$236.1K0.00%−754,352−79.3%Reduced
Gamco Investors, Inc. Et Al180,000$216.0K0.00%−5,000−2.7%Reduced
MetLife Investment Management179,588$215.5K0.00%−31,760−15.0%Reduced
Gabelli Funds LLC177,000$212.4K0.00%−4,000−2.2%Reduced
X-Square Capital, LLC169,663$207.0K0.10%−8,237−4.6%Reduced
Manufacturers Life Insurance Company, The164,462$197.4K0.00%−70,425−30.0%Reduced
Teton Advisors, Inc.162,000$194.4K0.07%−8,000−4.7%Reduced
Atom Investors LP154,337$185.2K0.02%+154,337New
Van Eck Associates Corp139,163$167.0K0.00%+6,228+4.7%Added
Scientech Research LLC137,093$164.5K0.09%+137,093New
New York State Common Retirement Fund127,900$153.5K0.00%00.0%Unchanged
Two Sigma Securities, LLC125,195$150.2K0.01%+113,578+977.7%Added
Csenge Advisory Group117,000$140.4K0.01%00.0%Unchanged
Arizona State Retirement System116,850$140.2K0.00%−2,007−1.7%Reduced
Highline Wealth Partners LLC116,680$140.0K0.06%00.0%Unchanged
Blair William & Co109,786$131.7K0.00%00.0%Unchanged
Cambridge Investment Research Advisors, Inc.105,060$126.0K0.00%−11,179−9.6%Reduced
Prudential Financial Inc104,996$126.0K0.00%00.0%Unchanged
Ameriprise Financial Inc102,991$123.6K0.00%−7,700−7.0%Reduced
Advisor Group Holdings, Inc.100,054$120.1K0.00%−6,622−6.2%Reduced
Intrepid Capital Management Inc100,000$120.0K0.08%00.0%Unchanged
AQR Capital Management LLC99,439$119.3K0.00%−227,216−69.6%Reduced
First Manhattan Co90,525$108.6K0.00%+50,000+123.4%Added
Comerica Bank90,000$108.0K0.00%+50,000+125.0%Added
RPg Family Wealth Advisory, LLC80,330$96.4K0.03%00.0%Unchanged
Hollencrest Capital Management78,980$94.8K0.00%00.0%Unchanged
Handelsbanken Fonder AB76,721$92.0K0.00%00.0%Unchanged
360 Financial, Inc.75,700$90.8K0.04%+13,200+21.1%Added
HSBC Holdings PLC74,133$89.0K0.00%+44,878+153.4%Added
ProShare Advisors LLC72,470$87.0K0.00%+5,704+8.5%Added
RSM US Wealth Management LLC70,000$84.0K0.00%00.0%Unchanged
Parallax Volatility Advisers, L.P.68,192$81.8K0.00%−66,088−49.2%Reduced
Cascade Financial Partners, LLC66,490$81.8K0.01%+66,490New
Cetera Investment Advisers65,695$78.8K0.00%+53,695+447.5%Added
Pictet Asset Management Holding SA65,495$78.6K0.00%00.0%Unchanged
Public Employees Retirement Association of Colorado61,502$74.0K0.00%00.0%Unchanged
Kestra Private Wealth Services, LLC56,500$67.8K0.00%+11,200+24.7%Added
XTX Topco Ltd56,123$67.3K0.01%+56,123New
Raymond James Financial Services Advisors, Inc.55,234$66.3K0.00%+3,380+6.5%Added