Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Opko Health, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 255
- +21 vs. Q4 2024
- Shares held
- 242.1M
- +46.0M (+23.4%) vs. Q4 2024
- Total value
- $401.4M
- +$113.2M (+39.3%) vs. Q4 2024
- New holders
- 44
- 76 more added
- Sold out
- 23
- 57 more reduced
1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Two Sigma Securities, LLC | 75,647 | $125.6K | 0.02% | −135−0.2% | Reduced |
| Wealth Enhancement Advisory Services, LLC | 74,706 | $124.0K | 0.00% | +45,798+158.4% | Added |
| CWM, LLC | 74,503 | $124.0K | 0.00% | +67,487+961.9% | Added |
| KLP Kapitalforvaltning AS | 74,000 | $122.8K | 0.00% | 00.0% | Unchanged |
| CIBC World Markets Corp | 70,769 | $117.5K | 0.00% | +40,287+132.2% | Added |
| ProShare Advisors LLC | 69,045 | $114.6K | 0.00% | −22,685−24.7% | Reduced |
| Cascade Financial Partners, LLC | 66,490 | $110.4K | 0.01% | 00.0% | Unchanged |
| Pictet Asset Management Holding SA | 65,495 | $108.7K | 0.00% | 00.0% | Unchanged |
| Public Employees Retirement Association of Colorado | 61,502 | $102.0K | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 60,801 | $100.9K | 0.00% | 00.0% | Unchanged |
| Cetera Investment Advisers | 60,556 | $100.5K | 0.00% | 00.0% | Unchanged |
| Kestra Private Wealth Services, LLC | 58,450 | $97.0K | 0.00% | −1,250−2.1% | Reduced |
| The PNC Financial Services Group, Inc. | 56,800 | $94.3K | 0.00% | 00.0% | Unchanged |
| Private Advisor Group, LLC | 55,301 | $91.8K | 0.00% | +20,000+56.7% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 55,140 | $91.5K | 0.00% | 00.0% | Unchanged |
| Mercer Global Advisors Inc | 54,957 | $91.2K | 0.00% | +11,790+27.3% | Added |
| Great West Life Assurance Co | 54,068 | $90.0K | 0.00% | 00.0% | Unchanged |
| Headlands Technologies LLC | 52,149 | $86.6K | 0.01% | +52,149 | New |
| First Manhattan Co | 51,750 | $85.9K | 0.00% | 00.0% | Unchanged |
| Transcend Wealth Collective, LLC | 50,850 | $84.4K | 0.01% | 00.0% | Unchanged |
| Group One Trading, L.P. | 50,794 | $84.3K | 0.00% | −596,291−92.2% | Reduced |
| Kestra Advisory Services, LLC | 50,307 | $83.5K | 0.00% | 00.0% | Unchanged |
| Farmers National Bank | 50,300 | $83.5K | 0.02% | 00.0% | Unchanged |
| Jump Financial, LLC | 49,070 | $81.5K | 0.00% | +49,070 | New |
| Captrust Financial Advisors | 48,482 | $80.5K | 0.00% | +10,952+29.2% | Added |
| Inspire Advisors, LLC | 47,130 | $78.2K | 0.01% | +47,130 | New |
| Humankind Investments LLC | 46,413 | $77.0K | 0.02% | −1,208−2.5% | Reduced |
| Aquatic Capital Management LLC | 45,966 | $76.3K | 0.00% | +45,966 | New |
| Tower Research Capital LLC (TRC) | 42,450 | $70.0K | 0.00% | +24,627+138.2% | Added |
| Shell Asset Management Co | 40,997 | $68.0K | 0.00% | +600+1.5% | Added |
| Atom Investors LP | 40,760 | $67.7K | 0.01% | +7,993+24.4% | Added |
| Pensionmark Financial Group, LLC | 40,618 | $67.4K | 0.00% | 00.0% | Unchanged |
| RK Asset Management, LLC | 40,485 | $67.0K | 0.06% | +4,000+11.0% | Added |
| HighTower Advisors, LLC | 38,906 | $64.6K | 0.00% | −1,085−2.7% | Reduced |
| HSBC Holdings PLC | 36,852 | $61.0K | 0.00% | −1,034−2.7% | Reduced |
| Victory Capital Management Inc | 36,616 | $60.8K | 0.00% | −1,711−4.5% | Reduced |
| RSM US Wealth Management LLC | 33,757 | $56.0K | 0.00% | −3,329−9.0% | Reduced |
| Operose Advisors LLC | 32,000 | $53.1K | 0.02% | 00.0% | Unchanged |
| Norris Perne & French LLP | 32,000 | $53.1K | 0.00% | +2,000+6.7% | Added |
| STRS Ohio | 31,900 | $53.0K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 31,889 | $52.9K | 0.00% | 00.0% | Unchanged |
| Brighton Jones LLC | 30,141 | $50.0K | 0.00% | +141+0.5% | Added |
| Brinker Capital Investments, LLC | 30,000 | $49.8K | 0.00% | 00.0% | Unchanged |
| IPG Investment Advisors LLC | 30,000 | $49.8K | 0.01% | 00.0% | Unchanged |
| Orion Portfolio Solutions, LLC | 30,000 | $49.8K | 0.00% | 00.0% | Unchanged |
| CIBC World Markets Inc. | 29,928 | $49.7K | 0.00% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 29,770 | $49.4K | 0.00% | −4,106−12.1% | Reduced |
| Capital Advisors Inc | 350,000 | $48.8K | 0.00% | +200,000+133.3% | Added |
| EP Wealth Advisors, LLC | 29,238 | $48.5K | 0.00% | +338+1.2% | Added |
| Equitable Holdings, Inc. | 28,931 | $48.0K | 0.00% | +10.0% | Added |
| Point72 (DIFC) Ltd | 28,907 | $48.0K | 0.00% | +6,162+27.1% | Added |
| Creative Planning | 28,097 | $46.6K | 0.00% | +3,833+15.8% | Added |
| Voleon Capital Management LP | 27,225 | $45.2K | 0.00% | +27,225 | New |
| PBMares Wealth Management LLC | 27,021 | $44.9K | 0.01% | 00.0% | Unchanged |
| Prudential Financial Inc | 26,766 | $44.4K | 0.00% | −4,590−14.6% | Reduced |
| Cim Investment Mangement Inc | 26,697 | $44.3K | 0.01% | −634−2.3% | Reduced |
| SlateStone Wealth, LLC | 25,770 | $43.0K | 0.00% | 00.0% | Unchanged |
| Pallas Capital Advisors LLC | 25,851 | $42.9K | 0.00% | +25,851 | New |
| Mackenzie Financial Corp | 25,843 | $42.9K | 0.00% | 00.0% | Unchanged |
| Diversify Wealth Management, LLC | 30,000 | $42.0K | 0.00% | 00.0% | Unchanged |
| FMR LLC | 24,388 | $40.5K | 0.00% | +92+0.4% | Added |
| Jain Global LLC | 24,200 | $40.2K | 0.00% | +24,200 | New |
| Moseley Investment Management Inc | 24,153 | $40.1K | 0.02% | 00.0% | Unchanged |
| Xponance, Inc. | 23,758 | $39.4K | 0.00% | +479+2.1% | Added |
| Toroso Investments, LLC | 23,618 | $39.2K | 0.00% | +23,618 | New |
| CIBC Asset Management Inc | 21,918 | $36.4K | 0.00% | 00.0% | Unchanged |
| Cerity Partners LLC | 21,528 | $35.7K | 0.00% | +21,528 | New |
| Principal Financial Group Inc | 21,125 | $35.1K | 0.00% | +3,093+17.2% | Added |
| LPL Financial LLC | 20,333 | $33.8K | 0.00% | −12,799−38.6% | Reduced |
| Aster Capital Management (DIFC) Ltd | 19,262 | $33.5K | 0.01% | +11,768+157.0% | Added |
| Sax Wealth Advisors, LLC | 20,110 | $33.4K | 0.00% | 00.0% | Unchanged |
| Sovereign Financial Group, Inc. | 20,084 | $33.3K | 0.01% | +100.0% | Added |
| N.E.W. Advisory Services LLC | 20,075 | $33.3K | 0.00% | 00.0% | Unchanged |
| GM Advisory Group, Inc. | 20,000 | $33.2K | 0.00% | +20,000 | New |
| Cumberland Advisors Inc | 19,500 | $32.4K | 0.01% | 00.0% | Unchanged |
| Sigma Planning Corp | 17,972 | $29.8K | 0.00% | 00.0% | Unchanged |
| Mariner, LLC | 17,463 | $29.0K | 0.00% | +17,463 | New |
| Shufro Rose & Co LLC | 17,000 | $28.2K | 0.00% | 00.0% | Unchanged |
| Stifel Financial Corp | 16,849 | $28.0K | 0.00% | +66+0.4% | Added |
| CAPROCK Group, Inc. | 16,770 | $27.8K | 0.00% | +16,770 | New |
| Westmount Partners, LLC | 16,550 | $27.5K | 0.01% | 00.0% | Unchanged |
| C2C Wealth Management, LLC | 16,405 | $27.2K | 0.03% | +1,390+9.3% | Added |
| Commons Capital, LLC | 16,300 | $27.1K | 0.02% | 00.0% | Unchanged |
| Oak Thistle LLC | 15,636 | $26.0K | 0.01% | +15,636 | New |
| Formidable Asset Management, LLC | 15,046 | $25.0K | 0.00% | 00.0% | Unchanged |
| Colony Family Offices, LLC | 14,729 | $24.4K | 0.01% | 00.0% | Unchanged |
| Sanctuary Advisors, LLC | 14,191 | $23.6K | 0.00% | +14,191 | New |
| Abel Hall, LLC | 14,170 | $23.5K | 0.01% | +4,044+39.9% | Added |
| Blueshift Asset Management, LLC | 13,870 | $23.0K | 0.01% | +13,870 | New |
| Schonfeld Strategic Advisors LLC | 13,100 | $21.7K | 0.00% | +13,100 | New |
| Canada Pension Plan Investment Board | 12,900 | $21.4K | 0.00% | +12,900 | New |
| R Squared Ltd | 12,290 | $20.4K | 0.02% | +12,290 | New |
| Farther Finance Advisors, LLC | 12,219 | $20.3K | 0.00% | +370+3.1% | Added |
| Jones Financial Companies LLLP | 11,625 | $19.8K | 0.00% | +3,000+34.8% | Added |
| Farringdon Capital, Ltd. | 11,834 | $19.6K | 0.01% | +11,834 | New |
| Traphagen Investment Advisors LLC | 11,680 | $19.4K | 0.00% | 00.0% | Unchanged |
| Colony Group, LLC | 11,524 | $19.1K | 0.00% | +11,524 | New |
| HBK Sorce Advisory LLC | 11,409 | $18.9K | 0.00% | 00.0% | Unchanged |
| Stillwater Capital Advisors, LLC | 11,380 | $18.9K | 0.00% | 00.0% | Unchanged |
| Gotham Asset Management, LLC | 11,056 | $18.4K | 0.00% | +11,056 | New |