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Opko Health, Inc.

OPK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000944809

No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Opko Health, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
236
+30 vs. Q3 2021
Shares held
190.2M
+6.95M (+3.8%) vs. Q3 2021
Total value
$914.8M
+$246.0M (+36.8%) vs. Q3 2021
New holders
53
58 more added
Sold out
23
63 more reduced

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 236 institutions
Q1 2021: 239 institutionsQ2 2021: 234 institutionsQ3 2021: 206 institutionsQ4 2021: 236 institutionsQ1 2022: 229 institutionsQ2 2022: 231 institutionsQ3 2022: 221 institutionsQ4 2022: 221 institutionsQ1 2023: 227 institutionsQ2 2023: 230 institutionsQ3 2023: 225 institutionsQ4 2023: 218 institutionsQ1 2024: 224 institutionsQ2 2024: 232 institutionsQ3 2024: 234 institutionsQ4 2024: 235 institutionsQ1 2025: 255 institutionsQ2 2025: 222 institutionsQ3 2025: 233 institutionsQ4 2025: 221 institutionsQ1 2026: 236 institutionsQ2 2026: 222 institutions
Value heldQ4 2021: $914.8M
Q1 2021: $817.1MQ2 2021: $773.3MQ3 2021: $668.9MQ4 2021: $914.8MQ1 2022: $671.0MQ2 2022: $479.9MQ3 2022: $349.6MQ4 2022: $224.8MQ1 2023: $259.3MQ2 2023: $375.6MQ3 2023: $267.6MQ4 2023: $256.6MQ1 2024: $190.7MQ2 2024: $227.7MQ3 2024: $278.1MQ4 2024: $290.3MQ1 2025: $401.4MQ2 2025: $270.4MQ3 2025: $303.6MQ4 2025: $251.1MQ1 2026: $229.4MQ2 2026: $303.4M
Institutions holding OPK and their total value by quarter
QuarterHoldersValue
Q2 2026222$303.4M
Q1 2026236$229.4M
Q4 2025221$251.1M
Q3 2025233$303.6M
Q2 2025222$270.4M
Q1 2025255$401.4M
Q4 2024235$290.3M
Q3 2024234$278.1M
Q2 2024232$227.7M
Q1 2024224$190.7M
Q4 2023218$256.6M
Q3 2023225$267.6M
Q2 2023230$375.6M
Q1 2023227$259.3M
Q4 2022221$224.8M
Q3 2022221$349.6M
Q2 2022231$479.9M
Q1 2022229$671.0M
Q4 2021236$914.8M
Q3 2021206$668.9M
Q2 2021234$773.3M
Q1 2021239$817.1M

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q3 2021.

Institutions holding OPK in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Sowell Financial Services LLC75,200$362.0K0.02%+5,600+8.0%Added
Landscape Capital Management, L.L.C.68,023$327.0K0.05%−700,784−91.2%Reduced
Raymond James & Associates66,982$322.0K0.00%−13,004−16.3%Reduced
Norris Perne & French LLP67,000$322.0K0.02%00.0%Unchanged
BDO Wealth Advisors, LLC67,000$322.0K0.03%+6,000+9.8%Added
Gsa Capital Partners LLP65,604$316.0K0.04%+65,604New
Public Employees Retirement Association of Colorado61,502$296.0K0.00%00.0%Unchanged
HSBC Holdings PLC58,734$286.0K0.00%+3,312+6.0%Added
Occudo Quantitative Strategies LP58,901$283.0K0.03%−77,001−56.7%Reduced
Raymond James Financial Services Advisors, Inc.58,221$280.0K0.00%+161+0.3%Added
DuPont Capital Management Corp57,455$276.0K0.01%−22,908−28.5%Reduced
Graham Capital Management, L.P.57,398$276.0K0.02%+57,398New
Shell Asset Management Co56,778$273.0K0.01%+268+0.5%Added
Cornerstone Investment Partners, LLC55,500$267.0K0.01%+55,500New
RPg Family Wealth Advisory, LLC55,330$266.1K0.11%00.0%Unchanged
Zurcher Kantonalbank (Zurich Cantonalbank)55,140$265.0K0.00%+10,074+22.4%Added
Amalgamated Bank51,797$249.0K0.00%−97−0.2%Reduced
Farmers National Bank50,300$241.9K0.08%−7,200−12.5%Reduced
Benchmark Financial Wealth Advisors, LLC48,502$233.0K0.10%00.0%Unchanged
Envestnet Asset Management Inc45,356$218.0K0.00%+45,356New
Tower Research Capital LLC (TRC)44,306$213.0K0.00%−41,869−48.6%Reduced
Algert Global LLC42,820$206.0K0.03%00.0%Unchanged
360 Financial, Inc.42,760$206.0K0.09%+8,300+24.1%Added
Captrust Financial Advisors42,468$204.0K0.00%+10,209+31.6%Added
Kestra Advisory Services, LLC41,336$199.0K0.00%+11,260+37.4%Added
Walleye Trading LLC40,680$196.0K0.00%+40,680New
HighTower Advisors, LLC40,355$195.0K0.00%+2,566+6.8%Added
Gotham Asset Management, LLC39,488$190.0K0.01%+11,823+42.7%Added
Engineers Gate Manager LP39,395$189.0K0.01%−44,776−53.2%Reduced
Mackenzie Financial Corp37,721$181.0K0.00%−3,982−9.5%Reduced
RK Asset Management, LLC36,685$176.0K0.16%+36,685New
Cim Investment Mangement Inc36,486$175.0K0.05%00.0%Unchanged
Pictet Asset Management SA34,600$166.0K0.00%00.0%Unchanged
STRS Ohio33,900$163.0K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.32,353$156.0K0.01%00.0%Unchanged
CIBC Asset Management Inc32,472$156.0K0.00%+4,283+15.2%Added
Transcend Wealth Collective, LLC32,077$154.0K0.01%+77+0.2%Added
Brighton Jones LLC30,000$144.0K0.01%−4,000−11.8%Reduced
Financial Architects, Inc29,200$140.0K0.02%00.0%Unchanged
AXA S.A.29,000$139.0K0.00%+29,000New
E Fund Management Co., Ltd.28,039$135.0K0.00%−18,503−39.8%Reduced
Twinbeech Capital LP27,816$134.0K0.01%+27,816New
US Bancorp27,123$131.0K0.00%00.0%Unchanged
State of Wyoming26,027$125.0K0.06%+26,027New
Janney Montgomery Scott LLC25,350$122.0K0.00%−700−2.7%Reduced
Arkadios Wealth Advisors25,000$120.0K0.02%00.0%Unchanged
Great West Life Assurance Co24,104$116.0K0.00%00.0%Unchanged
Teamwork Financial Advisors, LLC23,760$114.0K0.02%−20,275−46.0%Reduced
Platform Technology Partners23,725$114.0K0.05%−5,275−18.2%Reduced
Spire Wealth Management23,727$114.0K0.00%+23,727New
Pearl River Capital, LLC23,314$112.0K0.03%−5,077−17.9%Reduced
Shufro Rose & Co LLC22,500$108.0K0.01%00.0%Unchanged
Ausdal Financial Partners, Inc.22,175$107.0K0.01%00.0%Unchanged
First Manhattan Co21,500$103.0K0.00%−13,000−37.7%Reduced
Grandview Asset Management LLC21,350$103.0K0.04%−5,100−19.3%Reduced
Blueshift Asset Management, LLC21,276$102.0K0.01%+21,276New
LPL Financial LLC21,018$101.0K0.00%−6,635−24.0%Reduced
Cetera Advisors LLC20,100$97.0K0.00%+20,100New
Allianz Asset Management GmbH19,990$96.0K0.00%−21,756−52.1%Reduced
North Star Investment Management Corp.20,000$96.0K0.01%00.0%Unchanged
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management20,000$96.0K0.00%00.0%Unchanged
Farmers & Merchants Trust Co of Long Beach20,000$96.0K0.02%00.0%Unchanged
Sovereign Financial Group, Inc.20,000$96.0K0.04%+20,000New
Cumberland Advisors Inc19,500$94.0K0.02%00.0%Unchanged
Xponance, Inc.19,356$93.0K0.00%+573+3.1%Added
Mercer Global Advisors Inc19,200$92.0K0.00%+3,100+19.3%Added
National Asset Management, Inc.18,600$90.0K0.00%+18,600New
Formidable Asset Management, LLC18,446$86.0K0.02%−4,250−18.7%Reduced
Two Sigma Securities, LLC17,135$82.0K0.02%+17,135New
Stifel Financial Corp16,699$80.0K0.00%+189+1.1%Added
SlateStone Wealth, LLC15,770$76.0K0.02%00.0%Unchanged
Cetera Investment Advisers15,610$75.0K0.00%00.0%Unchanged
Sigma Planning Corp15,402$74.0K0.00%00.0%Unchanged
Modera Wealth Management, LLC15,196$73.0K0.00%+15,196New
Castle Rock Wealth Management, LLC22,500$73.0K0.03%+22,500New
Colony Family Offices, LLC14,729$71.0K0.03%00.0%Unchanged
Nisa Investment Advisors, LLC22,200$69.0K0.00%00.0%Unchanged
True North Advisors, LLC14,000$67.0K0.01%00.0%Unchanged
Natixis14,000$67.0K0.00%+14,000New
Columbia Asset Management14,000$67.0K0.01%+14,000New
Federated Hermes, Inc.13,427$65.0K0.00%−17,028−55.9%Reduced
Profund Advisors LLC13,519$65.0K0.00%+1,827+15.6%Added
Zacks Investment Management13,150$63.0K0.00%00.0%Unchanged
Wolverine Trading, LLC12,699$61.0K0.00%+12,699New
Vestor Capital, LLC12,110$58.0K0.01%00.0%Unchanged
Gladstone Institutional Advisory LLC11,622$56.0K0.00%+500+4.5%Added
Cetera Advisor Networks LLC11,336$55.0K0.00%00.0%Unchanged
Forum Financial Management, LP11,474$55.0K0.00%+11,474New
Capital Square, LLC12,100$54.0K0.04%00.0%Unchanged
Commons Capital, LLC11,300$54.0K0.05%+11,300New
Steward Partners Investment Advisory, LLC10,810$52.0K0.00%00.0%Unchanged
American Century Companies Inc10,553$51.0K0.00%+10,553New
Russell Investments Group, Ltd.10,437$50.0K0.00%+10,437New
Macquarie Group Ltd10,219$49.0K0.00%−5,276−34.0%Reduced
Gabelli & Co Investment Advisers, Inc.10,000$48.0K0.01%00.0%Unchanged
Diversified Trust Co10,000$48.0K0.00%00.0%Unchanged
KLCM Advisors, Inc.10,000$48.0K0.01%00.0%Unchanged
Baillie Gifford & Co6,635$32.0K0.00%00.0%Unchanged
Cornerstone Advisory, LLC6,000$29.0K0.00%+6,000New
M&R Capital Management Inc6,000$28.0K0.01%00.0%Unchanged