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Opko Health, Inc.

OPK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000944809

No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Opko Health, Inc. as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
222
−8 vs. Q1 2026
Shares held
202.4M
+1.61M (+0.8%) vs. Q1 2026
Total value
$303.4M
+$74.5M (+32.5%) vs. Q1 2026
New holders
23
74 more added
Sold out
31
52 more reduced

6 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 222 institutions
Q1 2021: 239 institutionsQ2 2021: 234 institutionsQ3 2021: 206 institutionsQ4 2021: 236 institutionsQ1 2022: 229 institutionsQ2 2022: 231 institutionsQ3 2022: 221 institutionsQ4 2022: 221 institutionsQ1 2023: 227 institutionsQ2 2023: 230 institutionsQ3 2023: 225 institutionsQ4 2023: 218 institutionsQ1 2024: 224 institutionsQ2 2024: 232 institutionsQ3 2024: 234 institutionsQ4 2024: 235 institutionsQ1 2025: 255 institutionsQ2 2025: 222 institutionsQ3 2025: 233 institutionsQ4 2025: 221 institutionsQ1 2026: 236 institutionsQ2 2026: 222 institutions
Value heldQ2 2026: $303.4M
Q1 2021: $817.1MQ2 2021: $773.3MQ3 2021: $668.9MQ4 2021: $914.8MQ1 2022: $671.0MQ2 2022: $479.9MQ3 2022: $349.6MQ4 2022: $224.8MQ1 2023: $259.3MQ2 2023: $375.6MQ3 2023: $267.6MQ4 2023: $256.6MQ1 2024: $190.7MQ2 2024: $227.7MQ3 2024: $278.1MQ4 2024: $290.3MQ1 2025: $401.4MQ2 2025: $270.4MQ3 2025: $303.6MQ4 2025: $251.1MQ1 2026: $229.4MQ2 2026: $303.4M
Institutions holding OPK and their total value by quarter
QuarterHoldersValue
Q2 2026222$303.4M
Q1 2026236$229.4M
Q4 2025221$251.1M
Q3 2025233$303.6M
Q2 2025222$270.4M
Q1 2025255$401.4M
Q4 2024235$290.3M
Q3 2024234$278.1M
Q2 2024232$227.7M
Q1 2024224$190.7M
Q4 2023218$256.6M
Q3 2023225$267.6M
Q2 2023230$375.6M
Q1 2023227$259.3M
Q4 2022221$224.8M
Q3 2022221$349.6M
Q2 2022231$479.9M
Q1 2022229$671.0M
Q4 2021236$914.8M
Q3 2021206$668.9M
Q2 2021234$773.3M
Q1 2021239$817.1M

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q1 2026.

Institutions holding OPK in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Zurcher Kantonalbank (Zurich Cantonalbank)55,140$82.7K0.00%00.0%Unchanged
Great West Life Assurance Co54,068$81.0K0.00%00.0%Unchanged
ProShare Advisors LLC52,766$79.1K0.00%−87,892−62.5%Reduced
First Manhattan Co52,150$78.2K0.00%00.0%Unchanged
Transcend Wealth Collective, LLC51,850$77.8K0.01%−55−0.1%Reduced
State of Wisconsin Investment Board51,523$77.3K0.00%+16,809+48.4%Added
Group One Trading, L.P.50,547$75.8K0.00%+9,885+24.3%Added
Mariner, LLC50,486$75.7K0.00%+11,140+28.3%Added
Farmers National Bank50,300$75.5K0.02%00.0%Unchanged
Victory Capital Management Inc43,623$65.4K0.00%−645−1.5%Reduced
Brighton Jones LLC43,153$64.7K0.00%+5,203+13.7%Added
Squarepoint Ops LLC41,591$62.4K0.00%+41,591New
Hollencrest Capital Management40,000$60.0K0.00%00.0%Unchanged
Caitong International Asset Management Co., Ltd39,868$59.8K0.01%+39,035+4,686.1%Added
STRS Ohio38,900$58.4K0.00%+7,000+21.9%Added
Xponance, Inc.38,748$58.1K0.00%+1,454+3.9%Added
The PNC Financial Services Group, Inc.37,000$55.5K0.00%00.0%Unchanged
Altshuler Shaham Ltd35,992$53.7K0.00%+21,217+143.6%Added
Warren Averett Asset Management, LLC34,330$51.5K0.00%+1,774+5.4%Added
Operose Advisors LLC32,000$48.0K0.01%00.0%Unchanged
Ameritas Investment Partners, Inc.31,889$47.8K0.00%00.0%Unchanged
RSM US Wealth Management LLC31,474$47.2K0.00%−2,283−6.8%Reduced
HighTower Advisors, LLC31,218$46.8K0.00%−2,093−6.3%Reduced
IPG Investment Advisors LLC30,000$45.0K0.01%00.0%Unchanged
EP Wealth Advisors, LLC29,722$44.6K0.00%−448−1.5%Reduced
Swiss Life Asset Management Ltd28,488$42.7K0.00%00.0%Unchanged
LPL Financial LLC28,147$42.2K0.00%−110.0%Reduced
Pensionmark Financial Group, LLC36,170$41.2K0.00%−30,350−45.6%Reduced
Schonfeld Strategic Advisors LLC26,973$40.5K0.00%+26,973New
Apella Capital, LLC27,021$40.3K0.00%00.0%Unchanged
SlateStone Wealth, LLC25,770$39.0K0.00%00.0%Unchanged
Arrow Financial Corp25,500$38.3K0.00%+500+2.0%Added
Diversify Wealth Management, LLC30,000$37.2K0.00%00.0%Unchanged
Diversify Advisory Services, LLC30,000$37.2K0.00%+30,000New
Tower Research Capital LLC (TRC)24,719$37.1K0.00%−103,994−80.8%Reduced
Simplex Trading, LLC23,233$34.8K0.00%+15,913+217.4%Added
SIH Partners, LLLP22,983$34.5K0.00%+6,296+37.7%Added
JustInvest LLC22,979$34.5K0.00%+11,383+98.2%Added
Graham Capital Management, L.P.22,834$34.3K0.00%−30,025−56.8%Reduced
CIBC Bancorp USA Inc.22,249$33.4K0.00%+1,528+7.4%Added
CIBC Asset Management Inc21,918$32.9K0.00%00.0%Unchanged
Raymond James Financial Inc21,912$32.9K0.00%−10,712−32.8%Reduced
Spartan Wealth Advisory Services LLC20,000$30.0K0.00%00.0%Unchanged
Jones Financial Companies LLLP19,181$29.3K0.00%+2,506+15.0%Added
Cumberland Advisors Inc19,500$29.3K0.01%00.0%Unchanged
Westmount Partners, LLC18,550$27.8K0.01%00.0%Unchanged
Two Sigma Securities, LLC18,270$27.4K0.00%+18,270New
Shufro Rose & Co LLC17,000$25.5K0.00%00.0%Unchanged
CAPROCK Group, Inc.16,770$25.2K0.00%00.0%Unchanged
Commons Capital, LLC16,300$24.4K0.02%00.0%Unchanged
Sigma Planning Corp15,807$23.7K0.00%00.0%Unchanged
FMR LLC15,336$23.0K0.00%−26,007−62.9%Reduced
Axq Capital, LP15,321$23.0K0.00%+15,321New
Sax Wealth Advisors, LLC20,050$22.9K0.00%−138−0.7%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH14,823$22.2K0.00%00.0%Unchanged
Colony Family Offices, LLC14,729$22.1K0.00%00.0%Unchanged
Merit Financial Group, LLC14,606$21.9K0.00%+14,606New
Nisa Investment Advisors, LLC14,221$21.3K0.00%+10,833+319.7%Added
GTS Securities LLC14,094$21.1K0.00%+14,094New
Key Financial Inc13,250$19.9K0.00%00.0%Unchanged
Sanctuary Advisors, LLC12,391$18.6K0.00%+12,391New
Pathstone Holdings, LLC12,383$18.6K0.00%+12,383New
Colony Group, LLC12,062$18.1K0.00%+962+8.7%Added
Traphagen Investment Advisors LLC11,680$17.5K0.00%00.0%Unchanged
Atomi Financial Group, Inc.11,382$17.1K0.00%−1,119−9.0%Reduced
CI Private Wealth, LLC11,370$17.1K0.00%+11,370New
Evergreen Capital Management LLC11,206$16.8K0.00%+11,206New
Nykredit A/S11,181$16.8K0.00%+11,181New
Steward Partners Investment Advisory, LLC11,110$16.7K0.00%+4,000+56.3%Added
Amalgamated Bank10,934$16.0K0.00%−1,995−15.4%Reduced
Stillwater Capital Advisors, LLC10,565$15.8K0.00%+10,565New
SEI Investments Co10,163$15.2K0.00%00.0%Unchanged
Diversified Trust Co10,122$15.2K0.00%00.0%Unchanged
KLCM Advisors, Inc.10,000$15.0K0.00%00.0%Unchanged
MRP Capital Investments, LLC10,000$15.0K0.01%00.0%Unchanged
Greenbush Financial Group, LLC10,000$15.0K0.00%00.0%Unchanged
HBK Sorce Advisory LLC11,057$14.9K0.00%00.0%Unchanged
Quantbot Technologies LP9,511$14.3K0.00%+609+6.8%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.8,880$13.3K0.00%−341−3.7%Reduced
Aventura Private Wealth, LLC8,400$12.6K0.00%00.0%Unchanged
Sterling Capital Management LLC8,122$12.2K0.00%−5,594−40.8%Reduced
Formidable Asset Management, LLC10,296$11.7K0.00%00.0%Unchanged
Allworth Financial LP7,192$10.8K0.00%−4,469−38.3%Reduced
National Bank of Canada5,200$7.80K0.00%00.0%Unchanged
EverSource Wealth Advisors, LLC3,727$5.59K0.00%+193+5.5%Added
Farther Finance Advisors, LLC3,408$5.11K0.00%+679+24.9%Added
Optiver Holding B.V.3,227$4.84K0.00%+1,448+81.4%Added
Gables Capital Management Inc.3,000$4.50K0.00%00.0%Unchanged
Smartleaf Asset Management LLC2,757$4.16K0.00%00.0%Unchanged
Parallel Advisors, LLC2,649$3.97K0.00%−1,000−27.4%Reduced
Essential Partners LLC2,533$3.80K0.00%+326+14.8%Added
Glen Eagle Advisors, LLC2,100$3.15K0.00%+2,100New
Harbour Investments, Inc.2,000$3.00K0.00%00.0%Unchanged
CoreCap Advisors, LLC1,600$2.40K0.00%00.0%Unchanged
US Bancorp1,568$2.35K0.00%+1,568New
GAMMA Investing LLC1,334$2.00K0.00%00.0%Unchanged
SJS Investment Consulting Inc.1,289$1.93K0.00%+1,265+5,270.8%Added
Godfrey Financial Associates, Inc.1,250$1.88K0.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co1,227$1.84K0.00%+1,000+440.5%Added
PFS Partners, LLC1,100$1.65K0.00%00.0%Unchanged