Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Opko Health, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 236
- +21 vs. Q4 2025
- Shares held
- 201.2M
- +34.3M (+20.5%) vs. Q4 2025
- Total value
- $229.4M
- +$19.5M (+9.3%) vs. Q4 2025
- New holders
- 44
- 59 more added
- Sold out
- 23
- 62 more reduced
6 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Centerpoint Advisors, LLC | 100 | $0 | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 72 | $0 | 0.00% | 00.0% | Unchanged |
| LRI Investments, LLC | 1 | $1 | 0.00% | 00.0% | Unchanged |
| Keating Financial Advisory Services, Inc. | 1 | $1 | 0.00% | +1 | New |
| SBI Securities Co., Ltd. | 2 | $2 | 0.00% | 00.0% | Unchanged |
| Crewe Advisors LLC | 1 | $2 | 0.00% | 00.0% | Unchanged |
| Darwin Advisors, LLC | 5 | $5 | 0.00% | 00.0% | Unchanged |
| Wilkerson Advisory Group LLC | 4 | $5 | 0.00% | +4 | New |
| Dunhill Financial, LLC | 8 | $9 | 0.00% | −1−11.1% | Reduced |
| SJS Investment Consulting Inc. | 24 | $28 | 0.00% | +24 | New |
| Larson Financial Group LLC | 40 | $46 | 0.00% | 00.0% | Unchanged |
| MAI Capital Management | 43 | $50 | 0.00% | +43 | New |
| Sunbelt Securities, Inc. | 55 | $63 | 0.00% | +55 | New |
| Boreal Capital Management LLC | 69 | $79 | 0.00% | 00.0% | Unchanged |
| Root Financial Partners, LLC | 100 | $114 | 0.00% | 00.0% | Unchanged |
| Salem Investment Counselors Inc | 100 | $114 | 0.00% | +100 | New |
| Harbor Investment Advisory, LLC | 180 | $205 | 0.00% | 00.0% | Unchanged |
| Hilton Head Capital Partners, LLC | 200 | $228 | 0.00% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 227 | $259 | 0.00% | −1−0.4% | Reduced |
| Pittenger & Anderson Inc | 250 | $285 | 0.00% | 00.0% | Unchanged |
| Quadrant Capital Group LLC | 272 | $311 | 0.00% | +272 | New |
| SRS Capital Advisors, Inc. | 293 | $334 | 0.00% | +293 | New |
| IFP Advisors, Inc | 403 | $459 | 0.00% | −29−6.7% | Reduced |
| Rothschild Investment LLC | 552 | $629 | 0.00% | +103+22.9% | Added |
| True Wealth Design, LLC | 559 | $638 | 0.00% | −313−35.9% | Reduced |
| Caitong International Asset Management Co., Ltd | 833 | $950 | 0.00% | −38,399−97.9% | Reduced |
| Salomon & Ludwin, LLC | 877 | $1.00K | 0.00% | −44−4.8% | Reduced |
| Rockefeller Capital Management L.P. | 1,053 | $1.20K | 0.00% | +652+162.6% | Added |
| PFS Partners, LLC | 1,100 | $1.25K | 0.00% | 00.0% | Unchanged |
| Aster Capital Management (DIFC) Ltd | 806 | $1.34K | 0.00% | −602−42.8% | Reduced |
| Godfrey Financial Associates, Inc. | 1,250 | $1.43K | 0.00% | 00.0% | Unchanged |
| GAMMA Investing LLC | 1,334 | $1.52K | 0.00% | +1,334 | New |
| CoreCap Advisors, LLC | 1,600 | $1.82K | 0.00% | 00.0% | Unchanged |
| Optiver Holding B.V. | 1,779 | $2.03K | 0.00% | +386+27.7% | Added |
| Harbour Investments, Inc. | 2,000 | $2.28K | 0.00% | +2,000 | New |
| Signaturefd, LLC | 2,022 | $2.31K | 0.00% | +2,022 | New |
| Essential Partners LLC | 2,207 | $2.52K | 0.00% | +491+28.6% | Added |
| Smartleaf Asset Management LLC | 2,757 | $3.03K | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 2,729 | $3.08K | 0.00% | +2,621+2,426.9% | Added |
| Gables Capital Management Inc. | 3,000 | $3.42K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 3,388 | $3.86K | 0.00% | +2,076+158.2% | Added |
| EverSource Wealth Advisors, LLC | 3,534 | $4.03K | 0.00% | −2,091−37.2% | Reduced |
| Parallel Advisors, LLC | 3,649 | $4.16K | 0.00% | +3,649 | New |
| Aquatic Capital Management LLC | 4,166 | $4.75K | 0.00% | +4,166 | New |
| National Bank of Canada | 5,200 | $5.93K | 0.00% | −1,000−16.1% | Reduced |
| Steward Partners Investment Advisory, LLC | 7,110 | $8.11K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 7,320 | $8.34K | 0.00% | −86,561−92.2% | Reduced |
| Aventura Private Wealth, LLC | 8,400 | $9.58K | 0.00% | 00.0% | Unchanged |
| Quantbot Technologies LP | 8,902 | $10.1K | 0.00% | −113,845−92.7% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 9,221 | $10.5K | 0.00% | +3,176+52.5% | Added |
| KLCM Advisors, Inc. | 10,000 | $11.4K | 0.00% | 00.0% | Unchanged |
| MRP Capital Investments, LLC | 10,000 | $11.4K | 0.01% | 00.0% | Unchanged |
| Greenbush Financial Group, LLC | 10,000 | $11.4K | 0.00% | 00.0% | Unchanged |
| Sanibel Captiva Trust Company, Inc. | 10,000 | $11.4K | 0.00% | +10,000 | New |
| First Affirmative Financial Network | 10,108 | $11.5K | 0.00% | +10,108 | New |
| Diversified Trust Co | 10,122 | $11.5K | 0.00% | −252−2.4% | Reduced |
| SEI Investments Co | 10,163 | $11.6K | 0.00% | 00.0% | Unchanged |
| Frec Markets, Inc. | 10,542 | $12.0K | 0.00% | +10,542 | New |
| IMC-Chicago, LLC | 10,874 | $12.4K | 0.00% | +10,874 | New |
| HBK Sorce Advisory LLC | 11,057 | $12.6K | 0.00% | 00.0% | Unchanged |
| Colony Group, LLC | 11,100 | $12.7K | 0.00% | +11,100 | New |
| Formidable Asset Management, LLC | 10,296 | $13.0K | 0.00% | −1,000−8.9% | Reduced |
| JustInvest LLC | 11,596 | $13.2K | 0.00% | +11,596 | New |
| Allworth Financial LP | 11,661 | $13.3K | 0.00% | +3,510+43.1% | Added |
| Traphagen Investment Advisors LLC | 11,680 | $13.3K | 0.00% | 00.0% | Unchanged |
| Atomi Financial Group, Inc. | 12,501 | $14.3K | 0.00% | +1,001+8.7% | Added |
| Amalgamated Bank | 12,929 | $15.0K | 0.00% | 00.0% | Unchanged |
| Key Financial Inc | 13,250 | $15.1K | 0.00% | −2,000−13.1% | Reduced |
| Moody National Bank Trust Division | 13,554 | $15.5K | 0.00% | +13,554 | New |
| Sterling Capital Management LLC | 13,716 | $15.6K | 0.00% | −10,004−42.2% | Reduced |
| Mill Creek Capital Advisors, LLC | 14,383 | $16.4K | 0.00% | +2,000+16.2% | Added |
| Altshuler Shaham Ltd | 14,775 | $16.7K | 0.00% | +11,483+348.8% | Added |
| Colony Family Offices, LLC | 14,729 | $16.8K | 0.00% | 00.0% | Unchanged |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 14,823 | $16.9K | 0.00% | 00.0% | Unchanged |
| Stifel Financial Corp | 15,549 | $17.7K | 0.00% | +191+1.2% | Added |
| Sigma Planning Corp | 15,807 | $18.0K | 0.00% | 00.0% | Unchanged |
| Sequoia Financial Advisors, LLC | 16,264 | $18.5K | 0.00% | +16,264 | New |
| Commons Capital, LLC | 16,300 | $18.6K | 0.02% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 16,675 | $18.7K | 0.00% | +2,550+18.1% | Added |
| SIH Partners, LLLP | 16,687 | $19.0K | 0.00% | −87,647−84.0% | Reduced |
| CAPROCK Group, Inc. | 16,770 | $19.1K | 0.00% | 00.0% | Unchanged |
| Shufro Rose & Co LLC | 17,000 | $19.4K | 0.00% | 00.0% | Unchanged |
| Blueshift Asset Management, LLC | 17,036 | $19.4K | 0.01% | +17,036 | New |
| CIBC World Markets Inc. | 17,228 | $19.6K | 0.00% | 00.0% | Unchanged |
| Principal Financial Group Inc | 17,740 | $20.2K | 0.00% | −12−0.1% | Reduced |
| Westmount Partners, LLC | 18,550 | $21.1K | 0.01% | 00.0% | Unchanged |
| Cumberland Advisors Inc | 19,500 | $22.2K | 0.01% | 00.0% | Unchanged |
| Capital Advisors Inc | 20,000 | $22.8K | 0.00% | −350,000−94.6% | Reduced |
| Spartan Wealth Advisory Services LLC | 20,000 | $22.8K | 0.00% | +20,000 | New |
| CIBC Bancorp USA Inc. | 20,721 | $23.6K | 0.00% | +20,721 | New |
| CIBC Asset Management Inc | 21,918 | $25.0K | 0.00% | 00.0% | Unchanged |
| Sax Wealth Advisors, LLC | 20,188 | $25.4K | 0.00% | −110−0.5% | Reduced |
| Cerity Partners LLC | 23,471 | $26.8K | 0.00% | +6,089+35.0% | Added |
| Zacks Investment Management | 24,665 | $28.1K | 0.00% | +3,343+15.7% | Added |
| Mirabella Financial Services LLP | 24,906 | $28.4K | 0.00% | −168,816−87.1% | Reduced |
| Arrow Financial Corp | 25,000 | $28.5K | 0.00% | 00.0% | Unchanged |
| SlateStone Wealth, LLC | 25,770 | $29.0K | 0.00% | 00.0% | Unchanged |
| LPL Financial LLC | 28,158 | $32.1K | 0.00% | +5,700+25.4% | Added |
| Swiss Life Asset Management Ltd | 28,488 | $32.5K | 0.00% | +9,324+48.7% | Added |
| Diversify Wealth Management, LLC | 30,000 | $33.3K | 0.00% | 00.0% | Unchanged |