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Opko Health, Inc.

OPK
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000944809

No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.

Q1 2026 vs. Q4 2025

How the institutions holding Opko Health, Inc. changed between Q4 2025 and Q1 2026.

All holders in Q1 2026All holders in Q4 2025

13F holders of OPK: Q4 2025 compared with Q1 2026
MeasureQ4 2025Of which not filed for Q1 2026Q1 2026Change
Holders2216236+21
Shares199.6M32.7M201.2M+34.3M (+20.5%)
Value$251.1M$41.1M$229.4M+$19.5M (+9.3%)

6 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so the changes leave them out.

New holders (44)

Institutions that held Opko Health, Inc. at the end of Q1 2026 but not at the end of Q4 2025.

Institutions new to OPK in Q1 2026
InstitutionSharesValue% of portfolio
Vanguard Portfolio Management LLC14,769,719$16.8M0.00%
Vanguard Capital Management LLC14,499,164$16.5M0.00%
Vanguard Fiduciary Trust Co2,742,017$3.13M0.00%
OP Asset Management Ltd1,102,254$1.26M0.01%
First Trust Advisors LP500,273$570.3K0.00%
Kovack Advisors, Inc.459,700$524.1K0.03%
Vanguard Asset Management, Ltd294,013$335.2K0.00%
HSBC Holdings PLC238,281$272.8K0.00%
Vanguard Global Advisers, LLC181,766$207.2K0.00%
State of Wyoming167,020$190.4K0.02%
U.S. Capital Wealth Advisors, LLC133,261$151.9K0.00%
Fifth Third Bancorp128,791$146.8K0.00%
Vanguard Investments Australia, Ltd.110,958$126.5K0.00%
Renaissance Technologies LLC109,543$124.9K0.00%
Point72 Asset Management, L.P.93,335$106.4K0.00%
LGL Partners, LLC44,507$50.7K0.02%
Group One Trading, L.P.40,662$46.4K0.00%
Brighton Jones LLC37,950$43.3K0.00%
Abel Hall, LLC33,271$37.9K0.01%
Apella Capital, LLC27,021$33.5K0.00%
CIBC Bancorp USA Inc.20,721$23.6K0.00%
Spartan Wealth Advisory Services LLC20,000$22.8K0.00%
Blueshift Asset Management, LLC17,036$19.4K0.01%
Sequoia Financial Advisors, LLC16,264$18.5K0.00%
Moody National Bank Trust Division13,554$15.5K0.00%
JustInvest LLC11,596$13.2K0.00%
Colony Group, LLC11,100$12.7K0.00%
IMC-Chicago, LLC10,874$12.4K0.00%
Frec Markets, Inc.10,542$12.0K0.00%
First Affirmative Financial Network10,108$11.5K0.00%
Sanibel Captiva Trust Company, Inc.10,000$11.4K0.00%
Aquatic Capital Management LLC4,166$4.75K0.00%
Parallel Advisors, LLC3,649$4.16K0.00%
Signaturefd, LLC2,022$2.31K0.00%
Harbour Investments, Inc.2,000$2.28K0.00%
GAMMA Investing LLC1,334$1.52K0.00%
SRS Capital Advisors, Inc.293$3340.00%
Quadrant Capital Group LLC272$3110.00%
Salem Investment Counselors Inc100$1140.00%
Sunbelt Securities, Inc.55$630.00%
MAI Capital Management43$500.00%
SJS Investment Consulting Inc.24$280.00%
Wilkerson Advisory Group LLC4$50.00%
Keating Financial Advisory Services, Inc.1$10.00%

Sold out (23)

Institutions that held Opko Health, Inc. at the end of Q4 2025 and filed for Q1 2026 without it.

Not filed for Q1 2026 yet (6)

Institutions that held Opko Health, Inc. at the end of Q4 2025 and haven't filed a 13F for Q1 2026. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding OPK in Q4 2025 that haven't filed for Q1 2026
InstitutionShares, Q4 2025Value, Q4 2025
Vanguard Group Inc32,457,788$40.9M
Comerica Bank120,000$151.2K
RK Asset Management, LLC40,485$51.0K
CIBC World Markets Corp27,225$34.3K
CIBC Private Wealth Group, LLC5,000$6.30K
Motiv8 Investments LLC300$0