Opko Health, Inc.
OPK- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000944809
No open-market purchases or sales by Opko Health, Inc. insiders were filed in the last 90 days; 222 institutions reported holding it in 13F filings for Q2 2026, worth $303.4M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Opko Health, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 236
- +21 vs. Q4 2025
- Shares held
- 201.2M
- +34.3M (+20.5%) vs. Q4 2025
- Total value
- $229.4M
- +$19.5M (+9.3%) vs. Q4 2025
- New holders
- 44
- 59 more added
- Sold out
- 23
- 62 more reduced
6 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting OPK on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 222 | $303.4M |
| Q1 2026 | 236 | $229.4M |
| Q4 2025 | 221 | $251.1M |
| Q3 2025 | 233 | $303.6M |
| Q2 2025 | 222 | $270.4M |
| Q1 2025 | 255 | $401.4M |
| Q4 2024 | 235 | $290.3M |
| Q3 2024 | 234 | $278.1M |
| Q2 2024 | 232 | $227.7M |
| Q1 2024 | 224 | $190.7M |
| Q4 2023 | 218 | $256.6M |
| Q3 2023 | 225 | $267.6M |
| Q2 2023 | 230 | $375.6M |
| Q1 2023 | 227 | $259.3M |
| Q4 2022 | 221 | $224.8M |
| Q3 2022 | 221 | $349.6M |
| Q2 2022 | 231 | $479.9M |
| Q1 2022 | 229 | $671.0M |
| Q4 2021 | 236 | $914.8M |
| Q3 2021 | 206 | $668.9M |
| Q2 2021 | 234 | $773.3M |
| Q1 2021 | 239 | $817.1M |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Opko Health, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Signaturefd, LLC | 2,022 | $2.31K | 0.00% | +2,022 | New |
| Harbour Investments, Inc. | 2,000 | $2.28K | 0.00% | +2,000 | New |
| Optiver Holding B.V. | 1,779 | $2.03K | 0.00% | +386+27.7% | Added |
| CoreCap Advisors, LLC | 1,600 | $1.82K | 0.00% | 00.0% | Unchanged |
| GAMMA Investing LLC | 1,334 | $1.52K | 0.00% | +1,334 | New |
| Godfrey Financial Associates, Inc. | 1,250 | $1.43K | 0.00% | 00.0% | Unchanged |
| Aster Capital Management (DIFC) Ltd | 806 | $1.34K | 0.00% | −602−42.8% | Reduced |
| PFS Partners, LLC | 1,100 | $1.25K | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 1,053 | $1.20K | 0.00% | +652+162.6% | Added |
| Salomon & Ludwin, LLC | 877 | $1.00K | 0.00% | −44−4.8% | Reduced |
| Caitong International Asset Management Co., Ltd | 833 | $950 | 0.00% | −38,399−97.9% | Reduced |
| True Wealth Design, LLC | 559 | $638 | 0.00% | −313−35.9% | Reduced |
| Rothschild Investment LLC | 552 | $629 | 0.00% | +103+22.9% | Added |
| IFP Advisors, Inc | 403 | $459 | 0.00% | −29−6.7% | Reduced |
| SRS Capital Advisors, Inc. | 293 | $334 | 0.00% | +293 | New |
| Quadrant Capital Group LLC | 272 | $311 | 0.00% | +272 | New |
| Pittenger & Anderson Inc | 250 | $285 | 0.00% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 227 | $259 | 0.00% | −1−0.4% | Reduced |
| Hilton Head Capital Partners, LLC | 200 | $228 | 0.00% | 00.0% | Unchanged |
| Harbor Investment Advisory, LLC | 180 | $205 | 0.00% | 00.0% | Unchanged |
| Root Financial Partners, LLC | 100 | $114 | 0.00% | 00.0% | Unchanged |
| Salem Investment Counselors Inc | 100 | $114 | 0.00% | +100 | New |
| Boreal Capital Management LLC | 69 | $79 | 0.00% | 00.0% | Unchanged |
| Sunbelt Securities, Inc. | 55 | $63 | 0.00% | +55 | New |
| MAI Capital Management | 43 | $50 | 0.00% | +43 | New |
| Larson Financial Group LLC | 40 | $46 | 0.00% | 00.0% | Unchanged |
| SJS Investment Consulting Inc. | 24 | $28 | 0.00% | +24 | New |
| Dunhill Financial, LLC | 8 | $9 | 0.00% | −1−11.1% | Reduced |
| Darwin Advisors, LLC | 5 | $5 | 0.00% | 00.0% | Unchanged |
| Wilkerson Advisory Group LLC | 4 | $5 | 0.00% | +4 | New |
| SBI Securities Co., Ltd. | 2 | $2 | 0.00% | 00.0% | Unchanged |
| Crewe Advisors LLC | 1 | $2 | 0.00% | 00.0% | Unchanged |
| LRI Investments, LLC | 1 | $1 | 0.00% | 00.0% | Unchanged |
| Keating Financial Advisory Services, Inc. | 1 | $1 | 0.00% | +1 | New |
| Centerpoint Advisors, LLC | 100 | $0 | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 72 | $0 | 0.00% | 00.0% | Unchanged |
| Two Sigma Securities, LLC | 0 | $0 | 0.00% | −374,468−100.0% | Sold out |
| Millennium Management LLC | 0 | $0 | 0.00% | −265,268−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −198,821−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −191,201−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −115,298−100.0% | Sold out |
| Y-Intercept (Hong Kong) Ltd | 0 | $0 | 0.00% | −112,930−100.0% | Sold out |
| Teacher Retirement System of Texas | 0 | $0 | 0.00% | −52,815−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −50,650−100.0% | Sold out |
| Fisher Asset Management, LLC | 0 | $0 | 0.00% | −30,000−100.0% | Sold out |
| Brinker Capital Investments, LLC | 0 | $0 | 0.00% | −30,000−100.0% | Sold out |
| Atom Investors LP | 0 | $0 | 0.00% | −28,258−100.0% | Sold out |
| Mackenzie Financial Corp | 0 | $0 | 0.00% | −25,843−100.0% | Sold out |
| Cim Investment Mangement Inc | 0 | $0 | 0.00% | −25,804−100.0% | Sold out |
| StoneX Group Inc. | 0 | $0 | 0.00% | −21,599−100.0% | Sold out |
| Quantinno Capital Management LP | 0 | $0 | 0.00% | −17,716−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −15,277−100.0% | Sold out |
| Sanctuary Advisors, LLC | 0 | $0 | 0.00% | −14,758−100.0% | Sold out |
| Buckingham Strategic Partners | 0 | $0 | 0.00% | −11,664−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −10,637−100.0% | Sold out |
| US Bancorp | 0 | $0 | 0.00% | −500−100.0% | Sold out |
| Medallion Wealth Advisors, LLC | 0 | $0 | 0.00% | −200−100.0% | Sold out |
| Transamerica Financial Advisors, Inc. | 0 | $0 | 0.00% | −56−100.0% | Sold out |
| Atlantic Union Bankshares Corp | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| Vanguard Group Inc | – | – | – | – | Not filed |
| Comerica Bank | – | – | – | – | Not filed |
| RK Asset Management, LLC | – | – | – | – | Not filed |
| CIBC World Markets Corp | – | – | – | – | Not filed |
| CIBC Private Wealth Group, LLC | – | – | – | – | Not filed |
| Motiv8 Investments LLC | – | – | – | – | Not filed |