Lyra Therapeutics, Inc.
LYRADelisted Apr 20, 2026- Industry
- Surgical & Medical Instruments & Apparatus
- SEC CIK
- 0001327273
Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.
13F holders, Q2 2024
Institutional positions in Lyra Therapeutics, Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 51
- −28 vs. Q1 2024
- Shares held
- 32.7M
- −12.8M (−28.1%) vs. Q1 2024
- Total value
- $9.06M
- −$274.3M (−96.8%) vs. Q1 2024
- New holders
- 14
- 15 more added
- Sold out
- 42
- 13 more reduced
Compare with Q1 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 1 | $51.1K |
| Q4 2025 | 23 | $747.3K |
| Q3 2025 | 26 | $2.93M |
| Q2 2025 | 30 | $4.42M |
| Q1 2025 | 57 | $3.23M |
| Q4 2024 | 54 | $5.54M |
| Q3 2024 | 62 | $8.36M |
| Q2 2024 | 51 | $9.06M |
| Q1 2024 | 79 | $283.4M |
| Q4 2023 | 60 | $222.0M |
| Q3 2023 | 45 | $124.8M |
| Q2 2023 | 39 | $138.4M |
| Q1 2023 | 31 | $38.1M |
| Q4 2022 | 37 | $59.9M |
| Q3 2022 | 38 | $96.0M |
| Q2 2022 | 38 | $108.9M |
| Q1 2022 | 28 | $20.2M |
| Q4 2021 | 34 | $22.4M |
| Q3 2021 | 37 | $60.8M |
| Q2 2021 | 46 | $56.0M |
| Q1 2021 | 50 | $87.6M |
Institutions, Q2 2024
Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc.; share changes are against Q1 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Perceptive Advisors LLC | 12,757,562 | $3.53M | 0.09% | 00.0% | Unchanged |
| Citadel Advisors LLC | 4,772,816 | $1.32M | 0.00% | +433,715+10.0% | Added |
| BlackRock Inc. | 2,829,978 | $783.1K | 0.00% | +2,678,059+1,762.8% | Added |
| Samsara BioCapital, LLC | 2,780,261 | $769.3K | 0.16% | 00.0% | Unchanged |
| Vanguard Group Inc | 1,730,915 | $478.9K | 0.00% | +249,434+16.8% | Added |
| Ikarian Capital, LLC | 1,056,829 | $292.4K | 0.09% | 00.0% | Unchanged |
| Rosalind Advisors, Inc. | 1,034,773 | $286.3K | 0.23% | −109,751−9.6% | Reduced |
| Acadian Asset Management LLC | 985,631 | $271.0K | 0.00% | +985,631 | New |
| Morgan Stanley | 811,745 | $224.6K | 0.00% | +747,353+1,160.6% | Added |
| Geode Capital Management, LLC | 755,095 | $209.0K | 0.00% | +395,664+110.1% | Added |
| Two Sigma Advisers, LP | 681,600 | $188.6K | 0.00% | +537,700+373.7% | Added |
| Two Sigma Investments, LP | 490,861 | $135.8K | 0.00% | +307,118+167.1% | Added |
| New York State Common Retirement Fund | 382,900 | $105.9K | 0.00% | +382,900 | New |
| State Street Corp | 259,820 | $71.9K | 0.00% | +133,640+105.9% | Added |
| Boothbay Fund Management, LLC | 232,670 | $64.4K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 129,141 | $35.0K | 0.00% | +129,141 | New |
| Clearline Capital LP | 119,128 | $33.0K | 0.00% | 00.0% | Unchanged |
| Charles Schwab Investment Management Inc | 111,609 | $30.9K | 0.00% | +111,609 | New |
| Bank of America Corp | 86,459 | $23.9K | 0.00% | −73,138−45.8% | Reduced |
| Northern Trust Corp | 83,860 | $23.2K | 0.00% | +23,365+38.6% | Added |
| Bank of New York Mellon Corp | 77,423 | $21.4K | 0.00% | +77,423 | New |
| Alpine Global Management, LLC | 46,439 | $12.8K | 0.00% | +46,439 | New |
| Rhumbline Advisers | 43,385 | $12.0K | 0.00% | +43,089+14,557.1% | Added |
| Jane Street Group, LLC | 42,676 | $11.8K | 0.00% | −115,027−72.9% | Reduced |
| Susquehanna International Group, LLP | 35,160 | $9.73K | 0.00% | −308,162−89.8% | Reduced |
| XTX Topco Ltd | 33,951 | $9.39K | 0.00% | +33,951 | New |
| Alliancebernstein L.P. | 33,120 | $9.16K | 0.00% | +33,120 | New |
| Virtu Financial LLC | 31,690 | $9.00K | 0.00% | +19,762+165.7% | Added |
| Letko, Brosseau & Associates Inc | 31,900 | $8.83K | 0.00% | 00.0% | Unchanged |
| Y-Intercept (Hong Kong) Ltd | 27,516 | $7.61K | 0.00% | +6,985+34.0% | Added |
| Corebridge Financial, Inc. | 26,036 | $7.46K | 0.00% | +26,036 | New |
| Goldman Sachs Group Inc | 24,391 | $6.75K | 0.00% | −310,274−92.7% | Reduced |
| Invesco Ltd. | 22,824 | $6.32K | 0.00% | −532,409−95.9% | Reduced |
| Dimensional Fund Advisors LP | 21,471 | $5.94K | 0.00% | −169,515−88.8% | Reduced |
| JPMorgan Chase & Co | 20,659 | $5.72K | 0.00% | −88,746−81.1% | Reduced |
| Millennium Management LLC | 20,350 | $5.63K | 0.00% | −385,771−95.0% | Reduced |
| Wells Fargo & Company | 17,618 | $4.88K | 0.00% | +17,367+6,919.1% | Added |
| Barclays PLC | 16,604 | $4.59K | 0.00% | −16,213−49.4% | Reduced |
| UBS Group AG | 14,697 | $4.07K | 0.00% | +14,679+81,550.0% | Added |
| DLK Investment Management, LLC | 12,000 | $3.32K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 10,652 | $2.95K | 0.00% | −108,223−91.0% | Reduced |
| Tower Research Capital LLC (TRC) | 6,822 | $1.89K | 0.00% | −2,099−23.5% | Reduced |
| Ameritas Investment Partners, Inc. | 4,741 | $1.31K | 0.00% | +4,741 | New |
| National Bank of Canada | 3,700 | $1.10K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 4,873 | $1.00K | 0.00% | +4,219+645.1% | Added |
| California State Teachers Retirement System | 3,507 | $970 | 0.00% | +3,507 | New |
| Advisor Group Holdings, Inc. | 1,378 | $383 | 0.00% | −622−31.1% | Reduced |
| Comerica Bank | 1,159 | $321 | 0.00% | 00.0% | Unchanged |
| Farther Finance Advisors, LLC | 38 | $11 | 0.00% | +38 | New |
| Price T Rowe Associates Inc | 17,541 | $0 | 0.00% | +17,541 | New |
| Amalgamated Bank | 1,674 | $0 | 0.00% | +1,674 | New |
| Nantahala Capital Management, LLC | 0 | $0 | 0.00% | −2,820,982−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −2,742,460−100.0% | Sold out |
| VR Adviser, LLC | 0 | $0 | 0.00% | −2,576,093−100.0% | Sold out |
| Pura Vida Investments, LLC | 0 | $0 | 0.00% | −1,413,242−100.0% | Sold out |
| Ally Bridge Group (NY) LLC | 0 | $0 | 0.00% | −1,003,741−100.0% | Sold out |
| Tri Locum Partners LP | 0 | $0 | 0.00% | −978,793−100.0% | Sold out |
| Vestal Point Capital, LP | 0 | $0 | 0.00% | −800,000−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −768,214−100.0% | Sold out |
| Laurion Capital Management LP | 0 | $0 | 0.00% | −747,827−100.0% | Sold out |
| Woodline Partners LP | 0 | $0 | 0.00% | −676,554−100.0% | Sold out |
| Parkman Healthcare Partners LLC | 0 | $0 | 0.00% | −642,245−100.0% | Sold out |
| Ensign Peak Advisors, Inc | 0 | $0 | 0.00% | −591,311−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −528,118−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −357,319−100.0% | Sold out |
| Hudson Bay Capital Management LP | 0 | $0 | 0.00% | −250,000−100.0% | Sold out |
| Acuta Capital Partners, LLC | 0 | $0 | 0.00% | −173,320−100.0% | Sold out |
| Superstring Capital Management LP | 0 | $0 | 0.00% | −145,284−100.0% | Sold out |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −131,902−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −98,525−100.0% | Sold out |
| Man Group plc | 0 | $0 | 0.00% | −90,283−100.0% | Sold out |
| Bridgeway Capital Management, LLC | 0 | $0 | 0.00% | −86,800−100.0% | Sold out |
| Marathon Trading Investment Management LLC | 0 | $0 | 0.00% | −67,010−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −50,900−100.0% | Sold out |
| Cambridge Investment Research Advisors, Inc. | 0 | $0 | 0.00% | −41,563−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −32,118−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −31,459−100.0% | Sold out |
| American Century Companies Inc | 0 | $0 | 0.00% | −25,778−100.0% | Sold out |
| Occudo Quantitative Strategies LP | 0 | $0 | 0.00% | −22,820−100.0% | Sold out |
| Omers Administration Corp | 0 | $0 | 0.00% | −22,200−100.0% | Sold out |
| Cubist Systematic Strategies, LLC | 0 | $0 | 0.00% | −21,160−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −20,187−100.0% | Sold out |
| Prelude Capital Management, LLC | 0 | $0 | 0.00% | −15,400−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −14,042−100.0% | Sold out |
| Bank of Montreal | 0 | $0 | 0.00% | −13,900−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −11,670−100.0% | Sold out |
| Jefferies Financial Group Inc. | 0 | $0 | 0.00% | −11,400−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −10,718−100.0% | Sold out |
| Heritage Wealth Management, Inc./Texas | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Catalyst Funds Management Pty Ltd | 0 | $0 | 0.00% | −8,200−100.0% | Sold out |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | $0 | 0.00% | −5,710−100.0% | Sold out |
| Northwestern Mutual Wealth Management Co | 0 | $0 | 0.00% | −100−100.0% | Sold out |
| Macquarie Group Ltd | 0 | $0 | 0.00% | −1,375−100.0% | Sold out |