Lyra Therapeutics, Inc.
LYRADelisted Apr 20, 2026- Industry
- Surgical & Medical Instruments & Apparatus
- SEC CIK
- 0001327273
Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.
13F holders, Q2 2024
Institutional positions in Lyra Therapeutics, Inc. as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 51
- −28 vs. Q1 2024
- Shares held
- 32.7M
- −12.8M (−28.1%) vs. Q1 2024
- Total value
- $9.06M
- −$274.3M (−96.8%) vs. Q1 2024
- New holders
- 14
- 15 more added
- Sold out
- 42
- 13 more reduced
Compare with Q1 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 1 | $51.1K |
| Q4 2025 | 23 | $747.3K |
| Q3 2025 | 26 | $2.93M |
| Q2 2025 | 30 | $4.42M |
| Q1 2025 | 57 | $3.23M |
| Q4 2024 | 54 | $5.54M |
| Q3 2024 | 62 | $8.36M |
| Q2 2024 | 51 | $9.06M |
| Q1 2024 | 79 | $283.4M |
| Q4 2023 | 60 | $222.0M |
| Q3 2023 | 45 | $124.8M |
| Q2 2023 | 39 | $138.4M |
| Q1 2023 | 31 | $38.1M |
| Q4 2022 | 37 | $59.9M |
| Q3 2022 | 38 | $96.0M |
| Q2 2022 | 38 | $108.9M |
| Q1 2022 | 28 | $20.2M |
| Q4 2021 | 34 | $22.4M |
| Q3 2021 | 37 | $60.8M |
| Q2 2021 | 46 | $56.0M |
| Q1 2021 | 50 | $87.6M |
Institutions, Q2 2024
Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc.; share changes are against Q1 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Price T Rowe Associates Inc | 17,541 | $0 | 0.00% | +17,541 | New |
| Amalgamated Bank | 1,674 | $0 | 0.00% | +1,674 | New |
| Farther Finance Advisors, LLC | 38 | $11 | 0.00% | +38 | New |
| Comerica Bank | 1,159 | $321 | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 1,378 | $383 | 0.00% | −622−31.1% | Reduced |
| California State Teachers Retirement System | 3,507 | $970 | 0.00% | +3,507 | New |
| Royal Bank of Canada | 4,873 | $1.00K | 0.00% | +4,219+645.1% | Added |
| National Bank of Canada | 3,700 | $1.10K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 4,741 | $1.31K | 0.00% | +4,741 | New |
| Tower Research Capital LLC (TRC) | 6,822 | $1.89K | 0.00% | −2,099−23.5% | Reduced |
| Citigroup Inc | 10,652 | $2.95K | 0.00% | −108,223−91.0% | Reduced |
| DLK Investment Management, LLC | 12,000 | $3.32K | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 14,697 | $4.07K | 0.00% | +14,679+81,550.0% | Added |
| Barclays PLC | 16,604 | $4.59K | 0.00% | −16,213−49.4% | Reduced |
| Wells Fargo & Company | 17,618 | $4.88K | 0.00% | +17,367+6,919.1% | Added |
| Millennium Management LLC | 20,350 | $5.63K | 0.00% | −385,771−95.0% | Reduced |
| JPMorgan Chase & Co | 20,659 | $5.72K | 0.00% | −88,746−81.1% | Reduced |
| Dimensional Fund Advisors LP | 21,471 | $5.94K | 0.00% | −169,515−88.8% | Reduced |
| Invesco Ltd. | 22,824 | $6.32K | 0.00% | −532,409−95.9% | Reduced |
| Goldman Sachs Group Inc | 24,391 | $6.75K | 0.00% | −310,274−92.7% | Reduced |
| Corebridge Financial, Inc. | 26,036 | $7.46K | 0.00% | +26,036 | New |
| Y-Intercept (Hong Kong) Ltd | 27,516 | $7.61K | 0.00% | +6,985+34.0% | Added |
| Letko, Brosseau & Associates Inc | 31,900 | $8.83K | 0.00% | 00.0% | Unchanged |
| Virtu Financial LLC | 31,690 | $9.00K | 0.00% | +19,762+165.7% | Added |
| Alliancebernstein L.P. | 33,120 | $9.16K | 0.00% | +33,120 | New |
| XTX Topco Ltd | 33,951 | $9.39K | 0.00% | +33,951 | New |
| Susquehanna International Group, LLP | 35,160 | $9.73K | 0.00% | −308,162−89.8% | Reduced |
| Jane Street Group, LLC | 42,676 | $11.8K | 0.00% | −115,027−72.9% | Reduced |
| Rhumbline Advisers | 43,385 | $12.0K | 0.00% | +43,089+14,557.1% | Added |
| Alpine Global Management, LLC | 46,439 | $12.8K | 0.00% | +46,439 | New |
| Bank of New York Mellon Corp | 77,423 | $21.4K | 0.00% | +77,423 | New |
| Northern Trust Corp | 83,860 | $23.2K | 0.00% | +23,365+38.6% | Added |
| Bank of America Corp | 86,459 | $23.9K | 0.00% | −73,138−45.8% | Reduced |
| Charles Schwab Investment Management Inc | 111,609 | $30.9K | 0.00% | +111,609 | New |
| Clearline Capital LP | 119,128 | $33.0K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 129,141 | $35.0K | 0.00% | +129,141 | New |
| Boothbay Fund Management, LLC | 232,670 | $64.4K | 0.00% | 00.0% | Unchanged |
| State Street Corp | 259,820 | $71.9K | 0.00% | +133,640+105.9% | Added |
| New York State Common Retirement Fund | 382,900 | $105.9K | 0.00% | +382,900 | New |
| Two Sigma Investments, LP | 490,861 | $135.8K | 0.00% | +307,118+167.1% | Added |
| Two Sigma Advisers, LP | 681,600 | $188.6K | 0.00% | +537,700+373.7% | Added |
| Geode Capital Management, LLC | 755,095 | $209.0K | 0.00% | +395,664+110.1% | Added |
| Morgan Stanley | 811,745 | $224.6K | 0.00% | +747,353+1,160.6% | Added |
| Acadian Asset Management LLC | 985,631 | $271.0K | 0.00% | +985,631 | New |
| Rosalind Advisors, Inc. | 1,034,773 | $286.3K | 0.23% | −109,751−9.6% | Reduced |
| Ikarian Capital, LLC | 1,056,829 | $292.4K | 0.09% | 00.0% | Unchanged |
| Vanguard Group Inc | 1,730,915 | $478.9K | 0.00% | +249,434+16.8% | Added |
| Samsara BioCapital, LLC | 2,780,261 | $769.3K | 0.16% | 00.0% | Unchanged |
| BlackRock Inc. | 2,829,978 | $783.1K | 0.00% | +2,678,059+1,762.8% | Added |
| Citadel Advisors LLC | 4,772,816 | $1.32M | 0.00% | +433,715+10.0% | Added |
| Perceptive Advisors LLC | 12,757,562 | $3.53M | 0.09% | 00.0% | Unchanged |
| Nantahala Capital Management, LLC | 0 | $0 | 0.00% | −2,820,982−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −2,742,460−100.0% | Sold out |
| VR Adviser, LLC | 0 | $0 | 0.00% | −2,576,093−100.0% | Sold out |
| Pura Vida Investments, LLC | 0 | $0 | 0.00% | −1,413,242−100.0% | Sold out |
| Ally Bridge Group (NY) LLC | 0 | $0 | 0.00% | −1,003,741−100.0% | Sold out |
| Tri Locum Partners LP | 0 | $0 | 0.00% | −978,793−100.0% | Sold out |
| Vestal Point Capital, LP | 0 | $0 | 0.00% | −800,000−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −768,214−100.0% | Sold out |
| Laurion Capital Management LP | 0 | $0 | 0.00% | −747,827−100.0% | Sold out |
| Woodline Partners LP | 0 | $0 | 0.00% | −676,554−100.0% | Sold out |
| Parkman Healthcare Partners LLC | 0 | $0 | 0.00% | −642,245−100.0% | Sold out |
| Ensign Peak Advisors, Inc | 0 | $0 | 0.00% | −591,311−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −528,118−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −357,319−100.0% | Sold out |
| Hudson Bay Capital Management LP | 0 | $0 | 0.00% | −250,000−100.0% | Sold out |
| Acuta Capital Partners, LLC | 0 | $0 | 0.00% | −173,320−100.0% | Sold out |
| Superstring Capital Management LP | 0 | $0 | 0.00% | −145,284−100.0% | Sold out |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −131,902−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −98,525−100.0% | Sold out |
| Man Group plc | 0 | $0 | 0.00% | −90,283−100.0% | Sold out |
| Bridgeway Capital Management, LLC | 0 | $0 | 0.00% | −86,800−100.0% | Sold out |
| Marathon Trading Investment Management LLC | 0 | $0 | 0.00% | −67,010−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −50,900−100.0% | Sold out |
| Cambridge Investment Research Advisors, Inc. | 0 | $0 | 0.00% | −41,563−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −32,118−100.0% | Sold out |
| Balyasny Asset Management LLC | 0 | $0 | 0.00% | −31,459−100.0% | Sold out |
| American Century Companies Inc | 0 | $0 | 0.00% | −25,778−100.0% | Sold out |
| Occudo Quantitative Strategies LP | 0 | $0 | 0.00% | −22,820−100.0% | Sold out |
| Omers Administration Corp | 0 | $0 | 0.00% | −22,200−100.0% | Sold out |
| Cubist Systematic Strategies, LLC | 0 | $0 | 0.00% | −21,160−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −20,187−100.0% | Sold out |
| Prelude Capital Management, LLC | 0 | $0 | 0.00% | −15,400−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −14,042−100.0% | Sold out |
| Bank of Montreal | 0 | $0 | 0.00% | −13,900−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −11,670−100.0% | Sold out |
| Jefferies Financial Group Inc. | 0 | $0 | 0.00% | −11,400−100.0% | Sold out |
| Engineers Gate Manager LP | 0 | $0 | 0.00% | −10,718−100.0% | Sold out |
| Heritage Wealth Management, Inc./Texas | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| Catalyst Funds Management Pty Ltd | 0 | $0 | 0.00% | −8,200−100.0% | Sold out |
| Point72 Asia (Singapore) Pte. Ltd. | 0 | $0 | 0.00% | −5,710−100.0% | Sold out |
| Northwestern Mutual Wealth Management Co | 0 | $0 | 0.00% | −100−100.0% | Sold out |
| Macquarie Group Ltd | 0 | $0 | 0.00% | −1,375−100.0% | Sold out |