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Lyra Therapeutics, Inc.

LYRADelisted Apr 20, 2026
Industry
Surgical & Medical Instruments & Apparatus
SEC CIK
0001327273

Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.

13F holders, Q1 2021

Institutional positions in Lyra Therapeutics, Inc. as of Mar 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
50
No complete 13F data for Q4 2020
Shares held
7.56M
No complete 13F data for Q4 2020
Total value
$87.6M
No complete 13F data for Q4 2020

Holders and value by quarter

Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2021: 50 institutions
Q1 2021: 50 institutionsQ2 2021: 46 institutionsQ3 2021: 37 institutionsQ4 2021: 34 institutionsQ1 2022: 28 institutionsQ2 2022: 38 institutionsQ3 2022: 38 institutionsQ4 2022: 37 institutionsQ1 2023: 31 institutionsQ2 2023: 39 institutionsQ3 2023: 45 institutionsQ4 2023: 60 institutionsQ1 2024: 79 institutionsQ2 2024: 51 institutionsQ3 2024: 62 institutionsQ4 2024: 54 institutionsQ1 2025: 57 institutionsQ2 2025: 30 institutionsQ3 2025: 26 institutionsQ4 2025: 23 institutionsQ1 2026: 1 institutionQ2 2026: 0 institutions
Value heldQ1 2021: $87.6M
Q1 2021: $87.6MQ2 2021: $56.0MQ3 2021: $60.8MQ4 2021: $22.4MQ1 2022: $20.2MQ2 2022: $108.9MQ3 2022: $96.0MQ4 2022: $59.9MQ1 2023: $38.1MQ2 2023: $138.4MQ3 2023: $124.8MQ4 2023: $222.0MQ1 2024: $283.4MQ2 2024: $9.06MQ3 2024: $8.36MQ4 2024: $5.54MQ1 2025: $3.23MQ2 2025: $4.42MQ3 2025: $2.93MQ4 2025: $747.3KQ1 2026: $51.1KQ2 2026: $0
Institutions holding LYRA and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20261$51.1K
Q4 202523$747.3K
Q3 202526$2.93M
Q2 202530$4.42M
Q1 202557$3.23M
Q4 202454$5.54M
Q3 202462$8.36M
Q2 202451$9.06M
Q1 202479$283.4M
Q4 202360$222.0M
Q3 202345$124.8M
Q2 202339$138.4M
Q1 202331$38.1M
Q4 202237$59.9M
Q3 202238$96.0M
Q2 202238$108.9M
Q1 202228$20.2M
Q4 202134$22.4M
Q3 202137$60.8M
Q2 202146$56.0M
Q1 202150$87.6M

Institutions, Q1 2021

Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc..

Livermore's 13F data starts with Q1 2021, so Q1 2021 has no change from the previous quarter.

Institutions holding LYRA in Q1 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Perceptive Advisors LLC3,222,560$37.3M0.50%––
Polaris Venture Management Co. V, L.L.C.1,100,852$12.8M16.54%––
Ikarian Capital, LLC780,728$9.05M1.35%––
Soleus Capital Management, L.P.475,814$5.51M0.99%––
BlackRock Inc.348,394$4.04M0.00%––
Vanguard Group Inc211,886$2.46M0.00%––
JPMorgan Chase & Co147,400$1.71M0.00%––
ArrowMark Colorado Holdings LLC139,187$1.61M0.01%––
Morgan Stanley107,217$1.24M0.00%––
State Street Corp96,246$1.11M0.00%––
Geode Capital Management, LLC90,281$1.05M0.00%––
Boothbay Fund Management, LLC83,650$970.0K0.05%––
Deutsche Bank AG80,799$936.0K0.00%––
Two Sigma Investments, LP72,052$835.0K0.00%––
Northern Trust Corp64,451$746.0K0.00%––
Alliancebernstein L.P.61,310$711.0K0.00%––
Blair William & Co55,000$637.0K0.00%––
Bridgeway Capital Management, LLC49,000$568.0K0.01%––
Marshall Wace, LLP46,928$544.0K0.00%––
Advisor Group Holdings, Inc.42,479$491.0K0.00%––
Ensign Peak Advisors, Inc39,167$454.0K0.00%––
Envestnet Asset Management Inc36,792$426.0K0.00%––
Bank of America Corp32,364$374.0K0.00%––
Two Sigma Advisers, LP31,434$364.0K0.00%––
Pentwater Capital Management LP23,800$276.0K0.00%––
Nuveen Asset Management, LLC17,913$208.0K0.00%––
Parametric Portfolio Associates LLC16,961$197.0K0.00%––
Bank of New York Mellon Corp15,036$174.0K0.00%––
Charles Schwab Investment Management Inc14,177$165.0K0.00%––
Jacobs Levy Equity Management, Inc12,340$143.0K0.00%––
Goldman Sachs Group Inc10,943$127.0K0.00%––
California State Teachers Retirement System10,287$119.0K0.00%––
New York State Common Retirement Fund4,438$51.0K0.00%––
American International Group, Inc.3,965$46.0K0.00%––
UBS Group AG2,754$32.0K0.00%––
Royal Bank of Canada2,223$25.0K0.00%––
Wells Fargo & Company2,085$24.0K0.00%––
Harbour Investments, Inc.1,315$15.0K0.00%––
Tower Research Capital LLC (TRC)1,050$13.0K0.00%––
STRS Ohio1,100$12.0K0.00%––
Legal & General Group Plc759$9.00K0.00%––
Citigroup Inc671$8.00K0.00%––
Cardinal Capital Management, Inc.650$8.00K0.00%––
US Bancorp500$6.00K0.00%––
Laurel Wealth Advisors LLC500$6.00K0.00%––
Ameritas Investment Partners, Inc.363$4.00K0.00%––
Bank of Montreal192$2.00K0.00%––
Toth Financial Advisory Corp100$1.00K0.00%––
Sargent Bickham Lagudis LLC100$1.00K0.00%––
Parallel Advisors, LLC10$00.00%––