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Lyra Therapeutics, Inc.

LYRADelisted Apr 20, 2026
Industry
Surgical & Medical Instruments & Apparatus
SEC CIK
0001327273

Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.

13F holders, Q1 2026

Institutional positions in Lyra Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

LYRA is no longer listed, and 13F filings after Q4 2025 list far fewer holders. See Q4 2025

Institutional holders
1
−20 vs. Q4 2025
Shares held
104.1K
−138.5K (−57.1%) vs. Q4 2025
Total value
$51.1K
−$696.1K (−93.2%) vs. Q4 2025
New holders
0
0 more added
Sold out
20
1 more reduced

2 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 1 institution
Q1 2021: 50 institutionsQ2 2021: 46 institutionsQ3 2021: 37 institutionsQ4 2021: 34 institutionsQ1 2022: 28 institutionsQ2 2022: 38 institutionsQ3 2022: 38 institutionsQ4 2022: 37 institutionsQ1 2023: 31 institutionsQ2 2023: 39 institutionsQ3 2023: 45 institutionsQ4 2023: 60 institutionsQ1 2024: 79 institutionsQ2 2024: 51 institutionsQ3 2024: 62 institutionsQ4 2024: 54 institutionsQ1 2025: 57 institutionsQ2 2025: 30 institutionsQ3 2025: 26 institutionsQ4 2025: 23 institutionsQ1 2026: 1 institutionQ2 2026: 0 institutions
Value heldQ1 2026: $51.1K
Q1 2021: $87.6MQ2 2021: $56.0MQ3 2021: $60.8MQ4 2021: $22.4MQ1 2022: $20.2MQ2 2022: $108.9MQ3 2022: $96.0MQ4 2022: $59.9MQ1 2023: $38.1MQ2 2023: $138.4MQ3 2023: $124.8MQ4 2023: $222.0MQ1 2024: $283.4MQ2 2024: $9.06MQ3 2024: $8.36MQ4 2024: $5.54MQ1 2025: $3.23MQ2 2025: $4.42MQ3 2025: $2.93MQ4 2025: $747.3KQ1 2026: $51.1KQ2 2026: $0
Institutions holding LYRA and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20261$51.1K
Q4 202523$747.3K
Q3 202526$2.93M
Q2 202530$4.42M
Q1 202557$3.23M
Q4 202454$5.54M
Q3 202462$8.36M
Q2 202451$9.06M
Q1 202479$283.4M
Q4 202360$222.0M
Q3 202345$124.8M
Q2 202339$138.4M
Q1 202331$38.1M
Q4 202237$59.9M
Q3 202238$96.0M
Q2 202238$108.9M
Q1 202228$20.2M
Q4 202134$22.4M
Q3 202137$60.8M
Q2 202146$56.0M
Q1 202150$87.6M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc.; share changes are against Q4 2025.

Institutions holding LYRA in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Sabby Management, LLC104,059$51.1K0.89%−71,099−40.6%Reduced
Ikarian Capital, LLC0$00.00%−21,161−100.0%Sold out
DRW Securities, LLC0$00.00%−16,812−100.0%Sold out
Geode Capital Management, LLC0$00.00%−12,249−100.0%Sold out
Artia Global Partners LP0$00.00%−8,756−100.0%Sold out
BlackRock, Inc.0$00.00%−2,394−100.0%Sold out
Tower Research Capital LLC (TRC)0$00.00%−2,191−100.0%Sold out
Royal Bank of Canada0$00.00%−1,953−100.0%Sold out
UBS Group AG0$00.00%−675−100.0%Sold out
EverSource Wealth Advisors, LLC0$00.00%−338−100.0%Sold out
Morgan Stanley0$00.00%−334−100.0%Sold out
Jones Financial Companies LLLP0$00.00%−210−100.0%Sold out
Bank of America Corp0$00.00%−201−100.0%Sold out
SBI Securities Co., Ltd.0$00.00%−80−100.0%Sold out
JPMorgan Chase & Co0$00.00%−27−100.0%Sold out
Advisor Group Holdings, Inc.0$00.00%−22−100.0%Sold out
Bryn Mawr Trust Co0$00.00%−20−100.0%Sold out
BNP Paribas Arbitrage, SA0$00.00%−16−100.0%Sold out
Citigroup Inc0$00.00%−3−100.0%Sold out
IFP Advisors, Inc0$00.00%−1−100.0%Sold out
CWM, LLC0$00.00%−1−100.0%Sold out
Comerica Bank––––Not filed
Global Retirement Partners, LLC––––Not filed