Lyra Therapeutics, Inc.
LYRADelisted Apr 20, 2026- Industry
- Surgical & Medical Instruments & Apparatus
- SEC CIK
- 0001327273
Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.
13F holders, Q2 2023
Institutional positions in Lyra Therapeutics, Inc. as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 39
- +8 vs. Q1 2023
- Shares held
- 33.7M
- +14.8M (+78.1%) vs. Q1 2023
- Total value
- $138.4M
- +$100.3M (+263.2%) vs. Q1 2023
- New holders
- 11
- 12 more added
- Sold out
- 3
- 5 more reduced
Compare with Q1 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 1 | $51.1K |
| Q4 2025 | 23 | $747.3K |
| Q3 2025 | 26 | $2.93M |
| Q2 2025 | 30 | $4.42M |
| Q1 2025 | 57 | $3.23M |
| Q4 2024 | 54 | $5.54M |
| Q3 2024 | 62 | $8.36M |
| Q2 2024 | 51 | $9.06M |
| Q1 2024 | 79 | $283.4M |
| Q4 2023 | 60 | $222.0M |
| Q3 2023 | 45 | $124.8M |
| Q2 2023 | 39 | $138.4M |
| Q1 2023 | 31 | $38.1M |
| Q4 2022 | 37 | $59.9M |
| Q3 2022 | 38 | $96.0M |
| Q2 2022 | 38 | $108.9M |
| Q1 2022 | 28 | $20.2M |
| Q4 2021 | 34 | $22.4M |
| Q3 2021 | 37 | $60.8M |
| Q2 2021 | 46 | $56.0M |
| Q1 2021 | 50 | $87.6M |
Institutions, Q2 2023
Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc.; share changes are against Q1 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Perceptive Advisors LLC | 12,757,562 | $52.4M | 1.52% | +3,610,832+39.5% | Added |
| Armistice Capital, LLC | 4,012,036 | $16.5M | 0.41% | +4,012,036 | New |
| Nantahala Capital Management, LLC | 3,957,542 | $16.3M | 1.97% | +1,736,712+78.2% | Added |
| Citadel Advisors LLC | 2,849,178 | $11.7M | 0.01% | +2,841,244+35,811.0% | Added |
| Samsara BioCapital, LLC | 2,780,261 | $11.4M | 2.01% | +1,003,010+56.4% | Added |
| Pura Vida Investments, LLC | 1,413,242 | $5.72M | 2.37% | −583,730−29.2% | Reduced |
| Ikarian Capital, LLC | 978,626 | $4.02M | 1.42% | +634,941+184.7% | Added |
| VR Adviser, LLC | 924,170 | $3.80M | 0.61% | 00.0% | Unchanged |
| Vanguard Group Inc | 790,936 | $3.25M | 0.00% | 00.0% | Unchanged |
| Parkman Healthcare Partners LLC | 600,000 | $2.47M | 0.43% | +600,000 | New |
| Soleus Capital Management, L.P. | 592,417 | $2.43M | 0.27% | 00.0% | Unchanged |
| Alyeska Investment Group, L.P. | 481,446 | $1.96M | 0.01% | +481,446 | New |
| DAFNA Capital Management LLC | 361,084 | $1.48M | 0.41% | +361,084 | New |
| Ensign Peak Advisors, Inc | 302,235 | $1.24M | 0.00% | 00.0% | Unchanged |
| Boothbay Fund Management, LLC | 163,675 | $672.7K | 0.02% | +128,954+371.4% | Added |
| Geode Capital Management, LLC | 148,840 | $611.7K | 0.00% | 00.0% | Unchanged |
| Clearline Capital LP | 119,128 | $489.6K | 0.06% | 00.0% | Unchanged |
| Bank of America Corp | 112,814 | $463.7K | 0.00% | +8,046+7.7% | Added |
| Bridgeway Capital Management, LLC | 96,800 | $397.8K | 0.01% | −50,000−34.1% | Reduced |
| Renaissance Technologies LLC | 71,000 | $292.0K | 0.00% | +23,149+48.4% | Added |
| State Street Corp | 55,780 | $229.3K | 0.00% | +18,200+48.4% | Added |
| BlackRock Inc. | 48,614 | $199.8K | 0.00% | +7,234+17.5% | Added |
| Letko, Brosseau & Associates Inc | 31,900 | $131.1K | 0.00% | +31,900 | New |
| Northern Trust Corp | 29,713 | $122.1K | 0.00% | −116−0.4% | Reduced |
| Susquehanna International Group, LLP | 11,885 | $48.8K | 0.00% | +11,885 | New |
| Simplex Trading, LLC | 1,795 | $7.00K | 0.00% | +1,795 | New |
| Tower Research Capital LLC (TRC) | 1,442 | $5.93K | 0.00% | −8,530−85.5% | Reduced |
| Advisor Group Holdings, Inc. | 1,294 | $4.80K | 0.00% | +794+158.8% | Added |
| Ameliora Wealth Management Ltd. | 750 | $3.08K | 0.00% | 00.0% | Unchanged |
| Worth Asset Management, LLC | 650 | $2.67K | 0.00% | 00.0% | Unchanged |
| Morgan Stanley | 510 | $2.10K | 0.00% | +510 | New |
| US Bancorp | 500 | $2.06K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 500 | $2.06K | 0.00% | 00.0% | Unchanged |
| Rhumbline Advisers | 296 | $1.22K | 0.00% | +296 | New |
| Wells Fargo & Company | 119 | $489 | 0.00% | +5+4.4% | Added |
| JPMorgan Chase & Co | 34 | $140 | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 18 | $74 | 0.00% | −835−97.9% | Reduced |
| FMR LLC | 11 | $45 | 0.00% | +11 | New |
| Royal Bank of Canada | 74 | $0 | 0.00% | +74 | New |
| Millennium Management LLC | 0 | $0 | 0.00% | −58,092−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −28,300−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −11,280−100.0% | Sold out |