Lyra Therapeutics, Inc.
LYRADelisted Apr 20, 2026- Industry
- Surgical & Medical Instruments & Apparatus
- SEC CIK
- 0001327273
Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.
13F holders, Q3 2025
Institutional positions in Lyra Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 26
- −4 vs. Q2 2025
- Shares held
- 448.6K
- −45.4K (−9.2%) vs. Q2 2025
- Total value
- $2.93M
- −$1.49M (−33.7%) vs. Q2 2025
- New holders
- 4
- 4 more added
- Sold out
- 8
- 13 more reduced
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 1 | $51.1K |
| Q4 2025 | 23 | $747.3K |
| Q3 2025 | 26 | $2.93M |
| Q2 2025 | 30 | $4.42M |
| Q1 2025 | 57 | $3.23M |
| Q4 2024 | 54 | $5.54M |
| Q3 2024 | 62 | $8.36M |
| Q2 2024 | 51 | $9.06M |
| Q1 2024 | 79 | $283.4M |
| Q4 2023 | 60 | $222.0M |
| Q3 2023 | 45 | $124.8M |
| Q2 2023 | 39 | $138.4M |
| Q1 2023 | 31 | $38.1M |
| Q4 2022 | 37 | $59.9M |
| Q3 2022 | 38 | $96.0M |
| Q2 2022 | 38 | $108.9M |
| Q1 2022 | 28 | $20.2M |
| Q4 2021 | 34 | $22.4M |
| Q3 2021 | 37 | $60.8M |
| Q2 2021 | 46 | $56.0M |
| Q1 2021 | 50 | $87.6M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Perceptive Advisors LLC | 229,382 | $1.50M | 0.04% | −25,768−10.1% | Reduced |
| Sabby Management, LLC | 127,624 | $832.9K | 4.32% | +1,895+1.5% | Added |
| Vanguard Group Inc | 28,754 | $189.5K | 0.00% | −424−1.5% | Reduced |
| Ikarian Capital, LLC | 21,161 | $139.5K | 0.03% | 00.0% | Unchanged |
| Citadel Advisors LLC | 19,484 | $128.4K | 0.00% | +19,484 | New |
| Geode Capital Management, LLC | 10,986 | $72.4K | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 4,001 | $26.1K | 0.00% | +3,999+199,950.0% | Added |
| BlackRock, Inc. | 1,690 | $11.0K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 1,325 | $9.00K | 0.00% | +223+20.2% | Added |
| Morgan Stanley | 1,277 | $8.34K | 0.00% | −887−41.0% | Reduced |
| Citigroup Inc | 705 | $4.65K | 0.00% | −90−11.3% | Reduced |
| Tower Research Capital LLC (TRC) | 534 | $3.48K | 0.00% | −949−64.0% | Reduced |
| FMR LLC | 406 | $2.68K | 0.00% | −1,342−76.8% | Reduced |
| Signature Resources Capital Management, LLC | 400 | $2.61K | 0.00% | 00.0% | Unchanged |
| EverSource Wealth Advisors, LLC | 345 | $2.25K | 0.00% | −13−3.6% | Reduced |
| Jones Financial Companies LLLP | 210 | $1.36K | 0.00% | +200+2,000.0% | Added |
| Fortitude Family Office, LLC | 96 | $627 | 0.00% | +96 | New |
| SBI Securities Co., Ltd. | 80 | $522 | 0.00% | −5−5.9% | Reduced |
| JPMorgan Chase & Co | 27 | $178 | 0.00% | −165−85.9% | Reduced |
| Comerica Bank | 23 | $150 | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 22 | $143 | 0.00% | +22 | New |
| Bryn Mawr Trust Co | 20 | $131 | 0.00% | +20 | New |
| Bank of America Corp | 18 | $117 | 0.00% | −28,524−99.9% | Reduced |
| BNP Paribas Arbitrage, SA | 16 | $104 | 0.00% | −9−36.0% | Reduced |
| IFP Advisors, Inc | 2 | $13 | 0.00% | −304−99.3% | Reduced |
| CWM, LLC | 24 | $0 | 0.00% | −178−88.1% | Reduced |
| State of Wisconsin Investment Board | 0 | $0 | 0.00% | −10,500−100.0% | Sold out |
| Russell Investments Group, Ltd. | 0 | $0 | 0.00% | −1,594−100.0% | Sold out |
| Valley National Advisers Inc | 0 | $0 | 0.00% | −500−100.0% | Sold out |
| Barclays PLC | 0 | $0 | 0.00% | −48−100.0% | Sold out |
| Wells Fargo & Company | 0 | $0 | 0.00% | −39−100.0% | Sold out |
| Principal Securities, Inc. | 0 | $0 | 0.00% | −19−100.0% | Sold out |
| Nisa Investment Advisors, LLC | 0 | $0 | 0.00% | −10−100.0% | Sold out |
| Raymond James Financial Inc | 0 | $0 | 0.00% | −8−100.0% | Sold out |