Lyra Therapeutics, Inc.
LYRADelisted Apr 20, 2026- Industry
- Surgical & Medical Instruments & Apparatus
- SEC CIK
- 0001327273
Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.
13F holders, Q2 2021
Institutional positions in Lyra Therapeutics, Inc. as of Jun 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 46
- −4 vs. Q1 2021
- Shares held
- 6.98M
- −579.9K (−7.7%) vs. Q1 2021
- Total value
- $56.0M
- −$31.6M (−36.0%) vs. Q1 2021
- New holders
- 12
- 3 more added
- Sold out
- 16
- 21 more reduced
Compare with Q1 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 1 | $51.1K |
| Q4 2025 | 23 | $747.3K |
| Q3 2025 | 26 | $2.93M |
| Q2 2025 | 30 | $4.42M |
| Q1 2025 | 57 | $3.23M |
| Q4 2024 | 54 | $5.54M |
| Q3 2024 | 62 | $8.36M |
| Q2 2024 | 51 | $9.06M |
| Q1 2024 | 79 | $283.4M |
| Q4 2023 | 60 | $222.0M |
| Q3 2023 | 45 | $124.8M |
| Q2 2023 | 39 | $138.4M |
| Q1 2023 | 31 | $38.1M |
| Q4 2022 | 37 | $59.9M |
| Q3 2022 | 38 | $96.0M |
| Q2 2022 | 38 | $108.9M |
| Q1 2022 | 28 | $20.2M |
| Q4 2021 | 34 | $22.4M |
| Q3 2021 | 37 | $60.8M |
| Q2 2021 | 46 | $56.0M |
| Q1 2021 | 50 | $87.6M |
Institutions, Q2 2021
Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc.; share changes are against Q1 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Perceptive Advisors LLC | 3,222,560 | $25.9M | 0.34% | 00.0% | Unchanged |
| Polaris Venture Management Co. V, L.L.C. | 1,100,852 | $8.84M | 14.16% | 00.0% | Unchanged |
| Ikarian Capital, LLC | 624,684 | $5.02M | 0.90% | −156,044−20.0% | Reduced |
| Pura Vida Investments, LLC | 542,644 | $4.36M | 0.31% | +542,644 | New |
| Vanguard Group Inc | 220,029 | $1.77M | 0.00% | +8,143+3.8% | Added |
| Soleus Capital Management, L.P. | 183,076 | $1.47M | 0.23% | −292,738−61.5% | Reduced |
| Millennium Management LLC | 155,135 | $1.25M | 0.00% | +155,135 | New |
| ArrowMark Colorado Holdings LLC | 139,187 | $1.12M | 0.01% | 00.0% | Unchanged |
| Morgan Stanley | 85,411 | $685.0K | 0.00% | −21,806−20.3% | Reduced |
| Boothbay Fund Management, LLC | 83,155 | $668.0K | 0.03% | −495−0.6% | Reduced |
| Deutsche Bank AG | 76,441 | $614.0K | 0.00% | −4,358−5.4% | Reduced |
| Blair William & Co | 55,000 | $442.0K | 0.00% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 44,000 | $353.0K | 0.00% | +12,566+40.0% | Added |
| Bridgeway Capital Management, LLC | 41,900 | $336.0K | 0.01% | −7,100−14.5% | Reduced |
| Tibra Equities Europe Ltd | 40,000 | $321.0K | 0.10% | +40,000 | New |
| Ensign Peak Advisors, Inc | 39,167 | $314.0K | 0.00% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 36,102 | $289.0K | 0.00% | −54,179−60.0% | Reduced |
| ExodusPoint Capital Management, LP | 31,539 | $253.0K | 0.00% | +31,539 | New |
| Bank of America Corp | 30,987 | $249.0K | 0.00% | −1,377−4.3% | Reduced |
| Ergoteles LLC | 31,000 | $249.0K | 0.01% | +31,000 | New |
| Two Sigma Investments, LP | 23,884 | $192.0K | 0.00% | −48,168−66.9% | Reduced |
| Pentwater Capital Management LP | 23,800 | $191.0K | 0.00% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 21,529 | $173.0K | 0.00% | +21,529 | New |
| BlackRock Inc. | 20,120 | $161.0K | 0.00% | −328,274−94.2% | Reduced |
| Citadel Advisors LLC | 19,381 | $156.0K | 0.00% | +19,381 | New |
| Marshall Wace, LLP | 19,321 | $155.0K | 0.00% | −27,607−58.8% | Reduced |
| Walleye Capital LLC | 19,093 | $153.0K | 0.01% | +19,093 | New |
| HRT Financial LP | 18,602 | $149.0K | 0.00% | +18,602 | New |
| Trexquant Investment LP | 11,610 | $93.0K | 0.01% | +11,610 | New |
| Goldman Sachs Group Inc | 10,751 | $86.0K | 0.00% | −192−1.8% | Reduced |
| Advisor Group Holdings, Inc. | 4,434 | $36.0K | 0.00% | −38,045−89.6% | Reduced |
| Tower Research Capital LLC (TRC) | 1,397 | $11.0K | 0.00% | +347+33.0% | Added |
| UBS Group AG | 567 | $5.00K | 0.00% | −2,187−79.4% | Reduced |
| Cardinal Capital Management, Inc. | 650 | $5.00K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 523 | $4.00K | 0.00% | −1,562−74.9% | Reduced |
| US Bancorp | 500 | $4.00K | 0.00% | 00.0% | Unchanged |
| Laurel Wealth Advisors LLC | 500 | $4.00K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 396 | $3.00K | 0.00% | −1,827−82.2% | Reduced |
| Harbour Investments, Inc. | 175 | $1.00K | 0.00% | −1,140−86.7% | Reduced |
| JPMorgan Chase & Co | 34 | $0 | 0.00% | −147,366−100.0% | Reduced |
| New York State Common Retirement Fund | 62 | $0 | 0.00% | −4,376−98.6% | Reduced |
| Citigroup Inc | 49 | $0 | 0.00% | −622−92.7% | Reduced |
| Toth Financial Advisory Corp | 50 | $0 | 0.00% | −50−50.0% | Reduced |
| Parallel Advisors, LLC | 10 | $0 | 0.00% | 00.0% | Unchanged |
| Quadrant Capital Group LLC | 49 | $0 | 0.00% | +49 | New |
| Investors Research Corp | 15 | $0 | 0.00% | +15 | New |
| State Street Corp | 0 | $0 | 0.00% | −96,246−100.0% | Sold out |
| Northern Trust Corp | 0 | $0 | 0.00% | −64,451−100.0% | Sold out |
| Alliancebernstein L.P. | 0 | $0 | 0.00% | −61,310−100.0% | Sold out |
| Envestnet Asset Management Inc | 0 | $0 | 0.00% | −36,792−100.0% | Sold out |
| Nuveen Asset Management, LLC | 0 | $0 | 0.00% | −17,913−100.0% | Sold out |
| Parametric Portfolio Associates LLC | 0 | $0 | 0.00% | −16,961−100.0% | Sold out |
| Bank of New York Mellon Corp | 0 | $0 | 0.00% | −15,036−100.0% | Sold out |
| Charles Schwab Investment Management Inc | 0 | $0 | 0.00% | −14,177−100.0% | Sold out |
| Jacobs Levy Equity Management, Inc | 0 | $0 | 0.00% | −12,340−100.0% | Sold out |
| California State Teachers Retirement System | 0 | $0 | 0.00% | −10,287−100.0% | Sold out |
| American International Group, Inc. | 0 | $0 | 0.00% | −3,965−100.0% | Sold out |
| STRS Ohio | 0 | $0 | 0.00% | −1,100−100.0% | Sold out |
| Legal & General Group Plc | 0 | $0 | 0.00% | −759−100.0% | Sold out |
| Ameritas Investment Partners, Inc. | 0 | $0 | 0.00% | −363−100.0% | Sold out |
| Bank of Montreal | 0 | $0 | 0.00% | −192−100.0% | Sold out |
| Sargent Bickham Lagudis LLC | 0 | $0 | 0.00% | −100−100.0% | Sold out |