Lyra Therapeutics, Inc.
LYRADelisted Apr 20, 2026- Industry
- Surgical & Medical Instruments & Apparatus
- SEC CIK
- 0001327273
Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.
13F holders, Q2 2022
Institutional positions in Lyra Therapeutics, Inc. as of Jun 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 38
- +10 vs. Q1 2022
- Shares held
- 19.3M
- +14.2M (+283.6%) vs. Q1 2022
- Total value
- $108.9M
- +$88.7M (+439.1%) vs. Q1 2022
- New holders
- 13
- 10 more added
- Sold out
- 3
- 9 more reduced
Compare with Q1 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 1 | $51.1K |
| Q4 2025 | 23 | $747.3K |
| Q3 2025 | 26 | $2.93M |
| Q2 2025 | 30 | $4.42M |
| Q1 2025 | 57 | $3.23M |
| Q4 2024 | 54 | $5.54M |
| Q3 2024 | 62 | $8.36M |
| Q2 2024 | 51 | $9.06M |
| Q1 2024 | 79 | $283.4M |
| Q4 2023 | 60 | $222.0M |
| Q3 2023 | 45 | $124.8M |
| Q2 2023 | 39 | $138.4M |
| Q1 2023 | 31 | $38.1M |
| Q4 2022 | 37 | $59.9M |
| Q3 2022 | 38 | $96.0M |
| Q2 2022 | 38 | $108.9M |
| Q1 2022 | 28 | $20.2M |
| Q4 2021 | 34 | $22.4M |
| Q3 2021 | 37 | $60.8M |
| Q2 2021 | 46 | $56.0M |
| Q1 2021 | 50 | $87.6M |
Institutions, Q2 2022
Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc.; share changes are against Q1 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Perceptive Advisors LLC | 9,146,730 | $51.7M | 1.62% | +5,924,170+183.8% | Added |
| Pura Vida Investments, LLC | 2,576,196 | $14.6M | 2.31% | +2,055,652+394.9% | Added |
| Nantahala Capital Management, LLC | 2,369,668 | $13.4M | 1.16% | +2,369,668 | New |
| Samsara BioCapital, LLC | 1,777,251 | $10.0M | 2.69% | +1,777,251 | New |
| VR Adviser, LLC | 924,170 | $5.22M | 1.03% | +924,170 | New |
| Vanguard Group Inc | 675,669 | $3.82M | 0.00% | +456,916+208.9% | Added |
| Soleus Capital Management, L.P. | 592,417 | $3.35M | 0.54% | +592,417 | New |
| Ikarian Capital, LLC | 347,338 | $1.96M | 0.81% | −75,000−17.8% | Reduced |
| Geode Capital Management, LLC | 120,476 | $680.0K | 0.00% | +83,012+221.6% | Added |
| Clearline Capital LP | 119,128 | $673.0K | 0.09% | −796−0.7% | Reduced |
| Bank of America Corp | 97,519 | $551.0K | 0.00% | +15,319+18.6% | Added |
| Millennium Management LLC | 88,705 | $501.0K | 0.00% | −24,002−21.3% | Reduced |
| CVI Holdings, LLC | 60,822 | $344.0K | 0.03% | +60,822 | New |
| Bridgeway Capital Management, LLC | 56,900 | $321.0K | 0.01% | −10,000−14.9% | Reduced |
| Ensign Peak Advisors, Inc | 56,229 | $318.0K | 0.00% | +17,062+43.6% | Added |
| BlackRock Inc. | 41,582 | $235.0K | 0.00% | +22,576+118.8% | Added |
| Renaissance Technologies LLC | 41,000 | $232.0K | 0.00% | +23,500+134.3% | Added |
| Boothbay Fund Management, LLC | 38,374 | $217.0K | 0.01% | −142−0.4% | Reduced |
| Two Sigma Advisers, LP | 38,400 | $217.0K | 0.00% | +18,400+92.0% | Added |
| State Street Corp | 34,243 | $193.0K | 0.00% | +34,243 | New |
| Northern Trust Corp | 29,829 | $169.0K | 0.00% | +29,829 | New |
| Two Sigma Investments, LP | 13,487 | $76.0K | 0.00% | +13,487 | New |
| Marshall Wace, LLP | 12,929 | $74.0K | 0.00% | +12,929 | New |
| HighMark Wealth Management LLC | 4,000 | $23.0K | 0.02% | +4,000 | New |
| UBS Group AG | 2,022 | $11.0K | 0.00% | +2,004+11,133.3% | Added |
| Tower Research Capital LLC (TRC) | 891 | $5.00K | 0.00% | +891 | New |
| Worth Asset Management, LLC | 650 | $4.00K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 500 | $3.00K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 500 | $3.00K | 0.00% | 00.0% | Unchanged |
| Laurel Wealth Advisors LLC | 500 | $3.00K | 0.00% | 00.0% | Unchanged |
| TD Waterhouse Canada Inc. | 200 | $1.07K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 111 | $1.00K | 0.00% | −426−79.3% | Reduced |
| CoreCap Advisors, LLC | 125 | $1.00K | 0.00% | +125 | New |
| JPMorgan Chase & Co | 34 | $0 | 0.00% | −7,725−99.6% | Reduced |
| Close Asset Management Ltd | 50 | $0 | 0.00% | −6,950−99.3% | Reduced |
| Royal Bank of Canada | 9 | $0 | 0.00% | −68−88.3% | Reduced |
| Investors Research Corp | 15 | $0 | 0.00% | 00.0% | Unchanged |
| Howe & Rusling Inc | 75 | $0 | 0.00% | +75 | New |
| Pentwater Capital Management LP | 0 | $0 | 0.00% | −60,000−100.0% | Sold out |
| Morgan Stanley | 0 | $0 | 0.00% | −8,085−100.0% | Sold out |
| Prospera Financial Services Inc | 0 | $0 | 0.00% | −100−100.0% | Sold out |