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Lyra Therapeutics, Inc.

LYRADelisted Apr 20, 2026
Industry
Surgical & Medical Instruments & Apparatus
SEC CIK
0001327273

Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.

13F holders, Q2 2025

Institutional positions in Lyra Therapeutics, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
30
−27 vs. Q1 2025
Shares held
494.0K
−17.9K (−3.5%) vs. Q1 2025Converted for a 1-for-50 split
Total value
$4.42M
+$1.19M (+37.0%) vs. Q1 2025
New holders
8
8 more added
Sold out
35
10 more reduced

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 30 institutions
Q1 2021: 50 institutionsQ2 2021: 46 institutionsQ3 2021: 37 institutionsQ4 2021: 34 institutionsQ1 2022: 28 institutionsQ2 2022: 38 institutionsQ3 2022: 38 institutionsQ4 2022: 37 institutionsQ1 2023: 31 institutionsQ2 2023: 39 institutionsQ3 2023: 45 institutionsQ4 2023: 60 institutionsQ1 2024: 79 institutionsQ2 2024: 51 institutionsQ3 2024: 62 institutionsQ4 2024: 54 institutionsQ1 2025: 57 institutionsQ2 2025: 30 institutionsQ3 2025: 26 institutionsQ4 2025: 23 institutionsQ1 2026: 1 institutionQ2 2026: 0 institutions
Value heldQ2 2025: $4.42M
Q1 2021: $87.6MQ2 2021: $56.0MQ3 2021: $60.8MQ4 2021: $22.4MQ1 2022: $20.2MQ2 2022: $108.9MQ3 2022: $96.0MQ4 2022: $59.9MQ1 2023: $38.1MQ2 2023: $138.4MQ3 2023: $124.8MQ4 2023: $222.0MQ1 2024: $283.4MQ2 2024: $9.06MQ3 2024: $8.36MQ4 2024: $5.54MQ1 2025: $3.23MQ2 2025: $4.42MQ3 2025: $2.93MQ4 2025: $747.3KQ1 2026: $51.1KQ2 2026: $0
Institutions holding LYRA and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20261$51.1K
Q4 202523$747.3K
Q3 202526$2.93M
Q2 202530$4.42M
Q1 202557$3.23M
Q4 202454$5.54M
Q3 202462$8.36M
Q2 202451$9.06M
Q1 202479$283.4M
Q4 202360$222.0M
Q3 202345$124.8M
Q2 202339$138.4M
Q1 202331$38.1M
Q4 202237$59.9M
Q3 202238$96.0M
Q2 202238$108.9M
Q1 202228$20.2M
Q4 202134$22.4M
Q3 202137$60.8M
Q2 202146$56.0M
Q1 202150$87.6M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc.; share changes are against Q1 2025.

Institutions holding LYRA in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Perceptive Advisors LLC255,150$2.29M0.09%00.0%UnchangedConverted for a 1-for-50 split
Sabby Management, LLC125,729$1.13M8.67%+125,729New
Vanguard Group Inc29,178$261.4K0.00%−6,134−17.4%ReducedConverted for a 1-for-50 split
Bank of America Corp28,542$255.7K0.00%+28,115+6,583.7%AddedConverted for a 1-for-50 split
Ikarian Capital, LLC21,161$189.6K0.06%00.0%UnchangedConverted for a 1-for-50 split
Geode Capital Management, LLC10,986$98.5K0.00%−9,334−45.9%ReducedConverted for a 1-for-50 split
State of Wisconsin Investment Board10,500$94.1K0.00%+10,500New
Morgan Stanley2,164$19.4K0.00%+852+64.9%AddedConverted for a 1-for-50 split
FMR LLC1,748$15.7K0.00%+584+50.1%AddedConverted for a 1-for-50 split
BlackRock, Inc.1,690$15.1K0.00%−58,690−97.2%ReducedConverted for a 1-for-50 split
Russell Investments Group, Ltd.1,594$14.3K0.00%+1,594New
Tower Research Capital LLC (TRC)1,483$13.3K0.00%+428+40.6%AddedConverted for a 1-for-50 split
Royal Bank of Canada1,102$10.0K0.00%+942+587.1%AddedConverted for a 1-for-50 split
Citigroup Inc795$7.12K0.00%+91+13.0%AddedConverted for a 1-for-50 split
Valley National Advisers Inc500$4.00K0.00%+500New
Signature Resources Capital Management, LLC400$3.58K0.00%+400New
EverSource Wealth Advisors, LLC358$3.21K0.00%+351+5,118.7%AddedConverted for a 1-for-50 split
CWM, LLC202$2.00K0.00%+68+51.3%AddedConverted for a 1-for-50 split
JPMorgan Chase & Co192$1.72K0.00%−934−82.9%ReducedConverted for a 1-for-50 split
SBI Securities Co., Ltd.85$7620.00%−0−0.5%ReducedConverted for a 1-for-50 split
Barclays PLC48$4300.00%−953−95.2%ReducedConverted for a 1-for-50 split
Wells Fargo & Company39$3490.00%−467−92.3%ReducedConverted for a 1-for-50 split
BNP Paribas Arbitrage, SA25$2240.00%−4,826−99.5%ReducedConverted for a 1-for-50 split
Comerica Bank23$2060.00%−0−0.8%ReducedConverted for a 1-for-50 split
Principal Securities, Inc.19$1700.00%+19New
Jones Financial Companies LLLP10$910.00%00.0%UnchangedConverted for a 1-for-50 split
Nisa Investment Advisors, LLC10$900.00%00.0%UnchangedConverted for a 1-for-50 split
IFP Advisors, Inc306$800.00%+306New
Raymond James Financial Inc8$720.00%+8New
UBS Group AG2$180.00%−8,683−100.0%ReducedConverted for a 1-for-50 split
Samsara BioCapital, LLC0$00.00%−27,803−100.0%Sold outConverted for a 1-for-50 split
ADAR1 Capital Management, LLC0$00.00%−10,664−100.0%Sold outConverted for a 1-for-50 split
State Street Corp0$00.00%−9,774−100.0%Sold outConverted for a 1-for-50 split
Goldman Sachs Group Inc0$00.00%−7,404−100.0%Sold outConverted for a 1-for-50 split
Two Sigma Advisers, LP0$00.00%−7,290−100.0%Sold outConverted for a 1-for-50 split
Northern Trust Corp0$00.00%−6,653−100.0%Sold outConverted for a 1-for-50 split
Boothbay Fund Management, LLC0$00.00%−4,680−100.0%Sold outConverted for a 1-for-50 split
Susquehanna International Group, LLP0$00.00%−4,351−100.0%Sold outConverted for a 1-for-50 split
Two Sigma Investments, LP0$00.00%−3,863−100.0%Sold outConverted for a 1-for-50 split
New York State Common Retirement Fund0$00.00%−3,096−100.0%Sold outConverted for a 1-for-50 split
Charles Schwab Investment Management Inc0$00.00%−2,232−100.0%Sold outConverted for a 1-for-50 split
Rhumbline Advisers0$00.00%−1,754−100.0%Sold outConverted for a 1-for-50 split
Bank of New York Mellon Corp0$00.00%−1,432−100.0%Sold outConverted for a 1-for-50 split
AQR Capital Management LLC0$00.00%−1,161−100.0%Sold outConverted for a 1-for-50 split
Jane Street Group, LLC0$00.00%−880−100.0%Sold outConverted for a 1-for-50 split
Alliancebernstein L.P.0$00.00%−662−100.0%Sold outConverted for a 1-for-50 split
SEI Investments Co0$00.00%−601−100.0%Sold outConverted for a 1-for-50 split
Mirae Asset Global ETFs Holdings Ltd.0$00.00%−580−100.0%Sold outConverted for a 1-for-50 split
Price T Rowe Associates Inc0$00.00%−351−100.0%Sold outConverted for a 1-for-50 split
Corebridge Financial, Inc.0$00.00%−474−100.0%Sold outConverted for a 1-for-50 split
Invesco Ltd.0$00.00%−473−100.0%Sold outConverted for a 1-for-50 split
Intech Investment Management LLC0$00.00%−331−100.0%Sold outConverted for a 1-for-50 split
SG Americas Securities, LLC0$00.00%−292−100.0%Sold outConverted for a 1-for-50 split
Squarepoint Ops LLC0$00.00%−306−100.0%Sold outConverted for a 1-for-50 split
Abel Hall, LLC0$00.00%−244−100.0%Sold outConverted for a 1-for-50 split
CIBC World Markets Corp0$00.00%−215−100.0%Sold outConverted for a 1-for-50 split
ProShare Advisors LLC0$00.00%−210−100.0%Sold outConverted for a 1-for-50 split
Sassicaia Capital Advisers LLC0$00.00%−200−100.0%Sold outConverted for a 1-for-50 split
Northwestern Mutual Wealth Management Co0$00.00%−120−100.0%Sold outConverted for a 1-for-50 split
Ameritas Investment Partners, Inc.0$00.00%−95−100.0%Sold outConverted for a 1-for-50 split
California State Teachers Retirement System0$00.00%−70−100.0%Sold outConverted for a 1-for-50 split
Bryn Mawr Trust Co0$00.00%−21−100.0%Sold outConverted for a 1-for-50 split
Sterling Capital Management LLC0$00.00%−2−100.0%Sold outConverted for a 1-for-50 split
Amalgamated Bank0$00.00%−33−100.0%Sold outConverted for a 1-for-50 split
Simplex Trading, LLC0$00.00%−26−100.0%Sold outConverted for a 1-for-50 split