Lyra Therapeutics, Inc.
LYRADelisted Apr 20, 2026- Industry
- Surgical & Medical Instruments & Apparatus
- SEC CIK
- 0001327273
Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.
13F holders, Q4 2022
Institutional positions in Lyra Therapeutics, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 37
- −1 vs. Q3 2022
- Shares held
- 19.1M
- −82.8K (−0.4%) vs. Q3 2022
- Total value
- $59.9M
- −$36.1M (−37.6%) vs. Q3 2022
- New holders
- 5
- 11 more added
- Sold out
- 6
- 6 more reduced
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 1 | $51.1K |
| Q4 2025 | 23 | $747.3K |
| Q3 2025 | 26 | $2.93M |
| Q2 2025 | 30 | $4.42M |
| Q1 2025 | 57 | $3.23M |
| Q4 2024 | 54 | $5.54M |
| Q3 2024 | 62 | $8.36M |
| Q2 2024 | 51 | $9.06M |
| Q1 2024 | 79 | $283.4M |
| Q4 2023 | 60 | $222.0M |
| Q3 2023 | 45 | $124.8M |
| Q2 2023 | 39 | $138.4M |
| Q1 2023 | 31 | $38.1M |
| Q4 2022 | 37 | $59.9M |
| Q3 2022 | 38 | $96.0M |
| Q2 2022 | 38 | $108.9M |
| Q1 2022 | 28 | $20.2M |
| Q4 2021 | 34 | $22.4M |
| Q3 2021 | 37 | $60.8M |
| Q2 2021 | 46 | $56.0M |
| Q1 2021 | 50 | $87.6M |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Perceptive Advisors LLC | 9,146,730 | $28.7M | 0.83% | 00.0% | Unchanged |
| Nantahala Capital Management, LLC | 2,220,830 | $6.97M | 0.63% | −25,000−1.1% | Reduced |
| Pura Vida Investments, LLC | 2,157,298 | $6.77M | 1.14% | −353,004−14.1% | Reduced |
| Samsara BioCapital, LLC | 1,777,251 | $5.58M | 1.20% | 00.0% | Unchanged |
| VR Adviser, LLC | 924,170 | $2.90M | 0.49% | 00.0% | Unchanged |
| Vanguard Group Inc | 790,936 | $2.48M | 0.00% | +3160.0% | Added |
| Soleus Capital Management, L.P. | 592,417 | $1.86M | 0.27% | 00.0% | Unchanged |
| Ikarian Capital, LLC | 343,685 | $1.08M | 0.45% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 302,235 | $949.0K | 0.00% | +239,025+378.1% | Added |
| Geode Capital Management, LLC | 148,840 | $467.0K | 0.00% | +1,981+1.3% | Added |
| Bridgeway Capital Management, LLC | 146,800 | $461.0K | 0.01% | +89,900+158.0% | Added |
| Clearline Capital LP | 119,128 | $374.1K | 0.07% | 00.0% | Unchanged |
| Bank of America Corp | 101,754 | $319.5K | 0.00% | +7,124+7.5% | Added |
| BlackRock Inc. | 40,114 | $126.0K | 0.00% | +1,099+2.8% | Added |
| Anson Funds Management LP | 39,127 | $122.9K | 0.04% | +39,127 | New |
| State Street Corp | 37,580 | $118.0K | 0.00% | +2,537+7.2% | Added |
| Renaissance Technologies LLC | 37,200 | $117.0K | 0.00% | −2,800−7.0% | Reduced |
| Boothbay Fund Management, LLC | 34,721 | $109.0K | 0.00% | 00.0% | Unchanged |
| Northern Trust Corp | 29,829 | $93.7K | 0.00% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 28,600 | $89.8K | 0.00% | −14,200−33.2% | Reduced |
| Citadel Advisors LLC | 25,277 | $79.4K | 0.00% | −11,859−31.9% | Reduced |
| Susquehanna International Group, LLP | 13,582 | $42.6K | 0.00% | −7,976−37.0% | Reduced |
| Tower Research Capital LLC (TRC) | 4,786 | $15.0K | 0.00% | +1,296+37.1% | Added |
| Belpointe Asset Management LLC | 3,703 | $11.6K | 0.00% | +3,703 | New |
| UBS Group AG | 3,397 | $10.7K | 0.00% | +303+9.8% | Added |
| Ameliora Wealth Management Ltd. | 750 | $2.35K | 0.00% | 00.0% | Unchanged |
| Worth Asset Management, LLC | 650 | $2.04K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 500 | $2.00K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 491 | $2.00K | 0.00% | +333+210.8% | Added |
| US Bancorp | 500 | $1.57K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 500 | $1.57K | 0.00% | 00.0% | Unchanged |
| FMR LLC | 450 | $1.41K | 0.00% | +450 | New |
| CoreCap Advisors, LLC | 125 | $393 | 0.00% | +125 | New |
| Wells Fargo & Company | 113 | $355 | 0.00% | +3+2.7% | Added |
| Investors Research Corp | 15 | $47 | 0.00% | 00.0% | Unchanged |
| Morgan Stanley | 1 | $3 | 0.00% | +1 | New |
| JPMorgan Chase & Co | 34 | $0 | 0.00% | 00.0% | Unchanged |
| Bank of New York Mellon Corp | 0 | $0 | 0.00% | −19,496−100.0% | Sold out |
| Millennium Management LLC | 0 | $0 | 0.00% | −18,908−100.0% | Sold out |
| Two Sigma Securities, LLC | 0 | $0 | 0.00% | −12,772−100.0% | Sold out |
| HighMark Wealth Management LLC | 0 | $0 | 0.00% | −4,000−100.0% | Sold out |
| BNP Paribas Arbitrage, SA | 0 | $0 | 0.00% | −30−100.0% | Sold out |
| Close Asset Management Ltd | 0 | $0 | 0.00% | −50−100.0% | Sold out |