Lyra Therapeutics, Inc.
LYRADelisted Apr 20, 2026- Industry
- Surgical & Medical Instruments & Apparatus
- SEC CIK
- 0001327273
Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.
13F holders, Q3 2022
Institutional positions in Lyra Therapeutics, Inc. as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 38
- 0 vs. Q2 2022
- Shares held
- 19.2M
- −111.9K (−0.6%) vs. Q2 2022
- Total value
- $96.0M
- −$12.9M (−11.8%) vs. Q2 2022
- New holders
- 7
- 8 more added
- Sold out
- 7
- 9 more reduced
Compare with Q2 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 1 | $51.1K |
| Q4 2025 | 23 | $747.3K |
| Q3 2025 | 26 | $2.93M |
| Q2 2025 | 30 | $4.42M |
| Q1 2025 | 57 | $3.23M |
| Q4 2024 | 54 | $5.54M |
| Q3 2024 | 62 | $8.36M |
| Q2 2024 | 51 | $9.06M |
| Q1 2024 | 79 | $283.4M |
| Q4 2023 | 60 | $222.0M |
| Q3 2023 | 45 | $124.8M |
| Q2 2023 | 39 | $138.4M |
| Q1 2023 | 31 | $38.1M |
| Q4 2022 | 37 | $59.9M |
| Q3 2022 | 38 | $96.0M |
| Q2 2022 | 38 | $108.9M |
| Q1 2022 | 28 | $20.2M |
| Q4 2021 | 34 | $22.4M |
| Q3 2021 | 37 | $60.8M |
| Q2 2021 | 46 | $56.0M |
| Q1 2021 | 50 | $87.6M |
Institutions, Q3 2022
Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc.; share changes are against Q2 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Perceptive Advisors LLC | 9,146,730 | $45.8M | 1.33% | 00.0% | Unchanged |
| Pura Vida Investments, LLC | 2,510,302 | $12.6M | 1.90% | −65,894−2.6% | Reduced |
| Nantahala Capital Management, LLC | 2,245,830 | $11.3M | 1.10% | −123,838−5.2% | Reduced |
| Samsara BioCapital, LLC | 1,777,251 | $8.90M | 2.08% | 00.0% | Unchanged |
| VR Adviser, LLC | 924,170 | $4.63M | 0.71% | 00.0% | Unchanged |
| Vanguard Group Inc | 790,620 | $3.96M | 0.00% | +114,951+17.0% | Added |
| Soleus Capital Management, L.P. | 592,417 | $2.97M | 0.40% | 00.0% | Unchanged |
| Ikarian Capital, LLC | 343,685 | $1.72M | 0.86% | −3,653−1.1% | Reduced |
| Geode Capital Management, LLC | 146,859 | $735.0K | 0.00% | +26,383+21.9% | Added |
| Clearline Capital LP | 119,128 | $597.0K | 0.08% | 00.0% | Unchanged |
| Bank of America Corp | 94,630 | $474.0K | 0.00% | −2,889−3.0% | Reduced |
| Ensign Peak Advisors, Inc | 63,210 | $317.0K | 0.00% | +6,981+12.4% | Added |
| Bridgeway Capital Management, LLC | 56,900 | $285.0K | 0.01% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 42,800 | $214.0K | 0.00% | +4,400+11.5% | Added |
| Renaissance Technologies LLC | 40,000 | $200.0K | 0.00% | −1,000−2.4% | Reduced |
| BlackRock Inc. | 39,015 | $196.0K | 0.00% | −2,567−6.2% | Reduced |
| Citadel Advisors LLC | 37,136 | $186.0K | 0.00% | +37,136 | New |
| State Street Corp | 35,043 | $176.0K | 0.00% | +800+2.3% | Added |
| Boothbay Fund Management, LLC | 34,721 | $174.0K | 0.01% | −3,653−9.5% | Reduced |
| Northern Trust Corp | 29,829 | $149.0K | 0.00% | 00.0% | Unchanged |
| Susquehanna International Group, LLP | 21,558 | $108.0K | 0.00% | +21,558 | New |
| Bank of New York Mellon Corp | 19,496 | $98.0K | 0.00% | +19,496 | New |
| Millennium Management LLC | 18,908 | $95.0K | 0.00% | −69,797−78.7% | Reduced |
| Two Sigma Securities, LLC | 12,772 | $64.0K | 0.01% | +12,772 | New |
| HighMark Wealth Management LLC | 4,000 | $20.0K | 0.02% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 3,490 | $17.0K | 0.00% | +2,599+291.7% | Added |
| UBS Group AG | 3,094 | $15.0K | 0.00% | +1,072+53.0% | Added |
| Worth Asset Management, LLC | 650 | $3.00K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 500 | $3.00K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 500 | $3.00K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 500 | $3.00K | 0.00% | +500 | New |
| Ameliora Wealth Management Ltd. | 750 | $3.00K | 0.00% | +750 | New |
| Wells Fargo & Company | 110 | $1.00K | 0.00% | −1−0.9% | Reduced |
| Royal Bank of Canada | 158 | $1.00K | 0.00% | +149+1,655.6% | Added |
| BNP Paribas Arbitrage, SA | 30 | $150 | 0.00% | +30 | New |
| JPMorgan Chase & Co | 34 | $0 | 0.00% | 00.0% | Unchanged |
| Close Asset Management Ltd | 50 | $0 | 0.00% | 00.0% | Unchanged |
| Investors Research Corp | 15 | $0 | 0.00% | 00.0% | Unchanged |
| CVI Holdings, LLC | 0 | $0 | 0.00% | −60,822−100.0% | Sold out |
| Two Sigma Investments, LP | 0 | $0 | 0.00% | −13,487−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −12,929−100.0% | Sold out |
| Laurel Wealth Advisors LLC | 0 | $0 | 0.00% | −500−100.0% | Sold out |
| TD Waterhouse Canada Inc. | 0 | $0 | 0.00% | −200−100.0% | Sold out |
| CoreCap Advisors, LLC | 0 | $0 | 0.00% | −125−100.0% | Sold out |
| Howe & Rusling Inc | 0 | $0 | 0.00% | −75−100.0% | Sold out |