Lyra Therapeutics, Inc.
LYRADelisted Apr 20, 2026- Industry
- Surgical & Medical Instruments & Apparatus
- SEC CIK
- 0001327273
Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.
13F holders, Q3 2022
Institutional positions in Lyra Therapeutics, Inc. as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 38
- 0 vs. Q2 2022
- Shares held
- 19.2M
- −111.9K (−0.6%) vs. Q2 2022
- Total value
- $96.0M
- −$12.9M (−11.8%) vs. Q2 2022
- New holders
- 7
- 8 more added
- Sold out
- 7
- 9 more reduced
Compare with Q2 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 1 | $51.1K |
| Q4 2025 | 23 | $747.3K |
| Q3 2025 | 26 | $2.93M |
| Q2 2025 | 30 | $4.42M |
| Q1 2025 | 57 | $3.23M |
| Q4 2024 | 54 | $5.54M |
| Q3 2024 | 62 | $8.36M |
| Q2 2024 | 51 | $9.06M |
| Q1 2024 | 79 | $283.4M |
| Q4 2023 | 60 | $222.0M |
| Q3 2023 | 45 | $124.8M |
| Q2 2023 | 39 | $138.4M |
| Q1 2023 | 31 | $38.1M |
| Q4 2022 | 37 | $59.9M |
| Q3 2022 | 38 | $96.0M |
| Q2 2022 | 38 | $108.9M |
| Q1 2022 | 28 | $20.2M |
| Q4 2021 | 34 | $22.4M |
| Q3 2021 | 37 | $60.8M |
| Q2 2021 | 46 | $56.0M |
| Q1 2021 | 50 | $87.6M |
Institutions, Q3 2022
Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc.; share changes are against Q2 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| JPMorgan Chase & Co | 34 | $0 | 0.00% | 00.0% | Unchanged |
| Close Asset Management Ltd | 50 | $0 | 0.00% | 00.0% | Unchanged |
| Investors Research Corp | 15 | $0 | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 30 | $150 | 0.00% | +30 | New |
| Wells Fargo & Company | 110 | $1.00K | 0.00% | −1−0.9% | Reduced |
| Royal Bank of Canada | 158 | $1.00K | 0.00% | +149+1,655.6% | Added |
| Worth Asset Management, LLC | 650 | $3.00K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 500 | $3.00K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 500 | $3.00K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 500 | $3.00K | 0.00% | +500 | New |
| Ameliora Wealth Management Ltd. | 750 | $3.00K | 0.00% | +750 | New |
| UBS Group AG | 3,094 | $15.0K | 0.00% | +1,072+53.0% | Added |
| Tower Research Capital LLC (TRC) | 3,490 | $17.0K | 0.00% | +2,599+291.7% | Added |
| HighMark Wealth Management LLC | 4,000 | $20.0K | 0.02% | 00.0% | Unchanged |
| Two Sigma Securities, LLC | 12,772 | $64.0K | 0.01% | +12,772 | New |
| Millennium Management LLC | 18,908 | $95.0K | 0.00% | −69,797−78.7% | Reduced |
| Bank of New York Mellon Corp | 19,496 | $98.0K | 0.00% | +19,496 | New |
| Susquehanna International Group, LLP | 21,558 | $108.0K | 0.00% | +21,558 | New |
| Northern Trust Corp | 29,829 | $149.0K | 0.00% | 00.0% | Unchanged |
| Boothbay Fund Management, LLC | 34,721 | $174.0K | 0.01% | −3,653−9.5% | Reduced |
| State Street Corp | 35,043 | $176.0K | 0.00% | +800+2.3% | Added |
| Citadel Advisors LLC | 37,136 | $186.0K | 0.00% | +37,136 | New |
| BlackRock Inc. | 39,015 | $196.0K | 0.00% | −2,567−6.2% | Reduced |
| Renaissance Technologies LLC | 40,000 | $200.0K | 0.00% | −1,000−2.4% | Reduced |
| Two Sigma Advisers, LP | 42,800 | $214.0K | 0.00% | +4,400+11.5% | Added |
| Bridgeway Capital Management, LLC | 56,900 | $285.0K | 0.01% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 63,210 | $317.0K | 0.00% | +6,981+12.4% | Added |
| Bank of America Corp | 94,630 | $474.0K | 0.00% | −2,889−3.0% | Reduced |
| Clearline Capital LP | 119,128 | $597.0K | 0.08% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 146,859 | $735.0K | 0.00% | +26,383+21.9% | Added |
| Ikarian Capital, LLC | 343,685 | $1.72M | 0.86% | −3,653−1.1% | Reduced |
| Soleus Capital Management, L.P. | 592,417 | $2.97M | 0.40% | 00.0% | Unchanged |
| Vanguard Group Inc | 790,620 | $3.96M | 0.00% | +114,951+17.0% | Added |
| VR Adviser, LLC | 924,170 | $4.63M | 0.71% | 00.0% | Unchanged |
| Samsara BioCapital, LLC | 1,777,251 | $8.90M | 2.08% | 00.0% | Unchanged |
| Nantahala Capital Management, LLC | 2,245,830 | $11.3M | 1.10% | −123,838−5.2% | Reduced |
| Pura Vida Investments, LLC | 2,510,302 | $12.6M | 1.90% | −65,894−2.6% | Reduced |
| Perceptive Advisors LLC | 9,146,730 | $45.8M | 1.33% | 00.0% | Unchanged |
| CVI Holdings, LLC | 0 | $0 | 0.00% | −60,822−100.0% | Sold out |
| Two Sigma Investments, LP | 0 | $0 | 0.00% | −13,487−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −12,929−100.0% | Sold out |
| Laurel Wealth Advisors LLC | 0 | $0 | 0.00% | −500−100.0% | Sold out |
| TD Waterhouse Canada Inc. | 0 | $0 | 0.00% | −200−100.0% | Sold out |
| CoreCap Advisors, LLC | 0 | $0 | 0.00% | −125−100.0% | Sold out |
| Howe & Rusling Inc | 0 | $0 | 0.00% | −75−100.0% | Sold out |