Lyra Therapeutics, Inc.
LYRADelisted Apr 20, 2026- Industry
- Surgical & Medical Instruments & Apparatus
- SEC CIK
- 0001327273
Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.
Open-market trades, last 90 days
Open-market purchases (P) and sales (S) by Lyra Therapeutics, Inc. insiders, counted by Form 4 filing. Trades with a flagged price and duplicate filings are left out.
- Open-market buys
- 0 filings
- Open-market sells
- 0 filings
- Insiders trading
- 0
- Net value
- $0
- Purchases minus sales
Insider roster
Directors, officers and 10% owners who have filed a Form 4 for Lyra Therapeutics, Inc., current and former, most recent filer first. Last reported holding is the position after the last non-derivative trade in their latest filing.
| Name | Title | Last reported holding | Last filing | Filings, past year |
|---|---|---|---|---|
| Smith W Bradford | Director | 0 | May 15, 2026 | 1 |
| Palasis Maria | Principal Executive Officer | 1,094,733 | Apr 3, 2026 | 3 |
| Cavalier Jason | Principal Financial Officer | 517,880 | Apr 3, 2026 | 2 |
| Edelman Joseph | 10% Owner | 14,026Indirect | Nov 13, 2025 | 2 |
| Perceptive Advisors LLC | 10% Owner | 14,026Indirect | Nov 13, 2025 | 2 |
| Perceptive Life Sciences Master Fund Ltd | 10% Owner | 14,026Indirect | Nov 13, 2025 | 2 |
| Perceptive LS (A), LLC | 10% Owner | 14,026Indirect | Nov 13, 2025 | 2 |
| Tobin James R | Director | – | May 16, 2025 | 0 |
| Merrifield C Ann | Director | 11,328 | May 16, 2025 | 0 |
| snyderman nancy lynn MD | Director | – | May 16, 2025 | 0 |
| Waksal Harlan | Executive Chair | 536,966 | Dec 11, 2024 | 0 |
| Poukalov Konstantin | Director | – | Jun 14, 2024 | 0 |
| Altman Michael Seth | Director | – | Jun 14, 2024 | 0 |
| Bishop John E | Chief Technology Officer | – | Feb 1, 2024 | 0 |
| Nieman Richard | Chief Medical Officer | – | Feb 1, 2024 | 0 |
| Anderson Edward T | Director, 10% Owner | 2,521,745Indirect | Jul 5, 2023 | 0 |
| North Bridge Venture Partners V-B LP | 10% Owner | 2,521,745Indirect | Jun 2, 2023 | 0 |
| North Bridge Venture Partners V A LP | 10% Owner | 2,521,745Indirect | Jun 2, 2023 | 0 |
| Damore Richard A | 10% Owner | 2,521,745Indirect | Jun 2, 2023 | 0 |
| North Bridge Venture Management V, L.P. | 10% Owner | 2,521,745Indirect | Jun 2, 2023 | 0 |
| North Bridge Venture Partners VI L P | 10% Owner | 2,521,745Indirect | Jun 2, 2023 | 0 |
| NBVM GP, LLC | 10% Owner | 2,521,745Indirect | Jun 2, 2023 | 0 |
| North Bridge Venture Management VI, L.P. | 10% Owner | 2,521,745Indirect | Jun 2, 2023 | 0 |
| Noyes Corinne | See Remarks | 36,667 | Feb 2, 2023 | 0 |
| Richard Robert E. | SVP, Technical Operations | 30,000 | Feb 2, 2023 | 0 |
| Nelson Pamela E. | SVP, Regulatory Affairs | – | Feb 15, 2022 | 0 |
Insider trades
Each row adds up one type of transaction in one Form 4 filing. Only open-market purchases (P) and sales (S) are shown by default; use the filters to see grants, option exercises and other codes.
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| Jan 8, 2026 (view filing) | Jan 6 | 2 days | Cavalier JasonChief Financial Officer | SSale | −769 | $3.36 | −$2.58K | −0.1%518.5K after | 10b5-1 |
| Jan 8, 2026 (view filing) | Jan 6 | 2 days | Palasis MariaPresident & CEO | SSale | −1.70K | $3.36 | −$5.72K | −0.2%1.10M after | 10b5-1 |
| Nov 13, 2025 (view filing)5:07 PM ET | Nov 11-13 | 2 days | Edelman Joseph and 3 others10% Owner | SSale | −45.9K | $3.98 | −$182.5K | −76.6%14.0K after | 6 lots |
| Nov 10, 2025 (view filing)5:08 PM ET | Nov 6-10 | 4 days | Edelman Joseph and 3 others10% Owner | SSale | −70.4K | $4.89 | −$344.2K | −79.0%18.7K after | 6 lots |
| Jul 14, 2025 (view filing) | Jul 10 | 4 days | Palasis MariaPresident & CEO | SSale | −1.56K | $8.91 | −$13.9K | −0.1%1.10M after | 10b5-1 |
| Jul 14, 2025 (view filing) | Jul 10 | 4 days | Cavalier JasonChief Financial Officer | SSale | −684 | $8.91 | −$6.09K | −0.1%519.3K after | 10b5-1 |
| Nov 13, 2023 (view filing) | Nov 10 | 3 days | Waksal HarlanExecutive Chair | PPurchase | +25.0K | $2.96 | +$74.0K | +10.6%262.0K after | |
| Jun 2, 2023 (view filing)4:15 PM ET | May 31 | 2 days | North Bridge Venture Partners V-B LP and 6 others10% Owner | PPurchase | +1.81M | $2.43 | +$4.39M | +252.0%2.52M after | 3 lotsDuplicate filing |
| Jun 2, 2023 (view filing)4:15 PM ET | May 31 | 2 days | North Bridge Venture Partners V-B LP and 6 others10% Owner | PPurchase | +902.7K | $0.125 | +$112.8K | –601.8K after | Derivative3 lotsDuplicate filing |
| Jun 2, 2023 (view filing)4:11 PM ET | May 31 | 2 days | Anderson Edward TDirector, 10% Owner | PPurchase | +1.81M | $2.43 | +$4.39M | +252.0%2.52M after | 3 lots |
| Jun 2, 2023 (view filing)4:11 PM ET | May 31 | 2 days | Anderson Edward TDirector, 10% Owner | PPurchase | +902.7K | $0.125 | +$112.8K | –601.8K after | Derivative3 lots |
| Jun 2, 2023 (view filing)4:11 PM ET | May 31 | 2 days | Edelman Joseph and 3 othersDirector, 10% Owner | PPurchase | +3.61M | $2.49 | +$9.00M | +45.9%11.5M after | |
| Jun 2, 2023 (view filing)4:11 PM ET | May 31 | 2 days | Edelman Joseph and 3 othersDirector, 10% Owner | PPurchase | +1.81M | – | – | –1.81M after | Derivative |
| Jun 13, 2022 (view filing) | Jun 10 | 3 days | Merrifield C AnnDirector | PPurchase | +4.00K | $5.05 | +$20.2K | +54.6%11.3K after | |
| May 17, 2022 (view filing) | May 13-16 | 4 days | Merrifield C AnnDirector | PPurchase | +3.83K | $4.83 | +$18.5K | +109.4%7.33K after | 2 lots |
| Apr 14, 2022 (view filing)4:53 PM ET | Apr 12 | 2 days | Edelman Joseph and 3 othersDirector, 10% Owner | PPurchase | +5.92M | $4.22 | +$25.0M | +306.3%7.86M after | |
| Apr 14, 2022 (view filing)4:14 PM ET | Apr 12 | 2 days | North Bridge Venture Partners V-B LP and 6 others10% Owner | PPurchase | +2.37M | $4.22 | +$10.0M | New position1.32M after | 3 lotsDuplicate filing |
| Apr 14, 2022 (view filing) | Apr 12 | 2 days | Anderson Edward TDirector, 10% Owner | PPurchase | +2.37M | $4.22 | +$10.0M | New position1.32M after | 3 lots |
| Apr 14, 2022 (view filing) | Apr 12 | 2 days | Anderson Edward TDirector, 10% Owner | PPurchase | +118.5K | $4.22 | +$500.0K | New position118.5K after | |
| Apr 13, 2022 (view filing) | Apr 12 | 1 day | Waksal HarlanExecutive Chair | PPurchase | +237.0K | $4.22 | +$1.00M | New position237.0K after |