Perceptive Life Sciences Master Fund Ltd
- SEC CIK
- 0001249675
In the past year, 1 open-market purchase filing worth $7.50M and 2 sale filings worth $526.7K.
Current role at each company
- IMTX Immatics N.V.Directoras of Aug 27, 2026
- FRNM Freenome, Inc.10% Owneras of Jul 22, 2026
- KARD Kardigan, Inc.Directoras of Jul 13, 2026
- LONA LeonaBio, Inc.Director, 10% Owneras of Jul 10, 2026
- MGTX MeiraGTx Holdings plcDirector, 10% Owneras of Jun 15, 2026
Show 24 more companies
- SLDB Solid Biosciences Inc.Director, 10% Owneras of Jun 11, 2026
- LYRA Lyra Therapeutics, Inc.10% Owneras of Nov 13, 2025
- ADGM Adagio Medical Holdings, Inc.10% Owneras of Oct 22, 2025
- OBIO Orchestra BioMed Holdings, Inc.10% Owneras of Aug 5, 2025
- ACRV Acrivon Therapeutics, Inc.10% Owneras of May 1, 2025
- ALDX Aldeyra Therapeutics, Inc.10% Owneras of Apr 7, 2025
- NAUT Nautilus Biotechnology, Inc.Director, 10% Owneras of Jun 17, 2024
- CERE Cerevel Therapeutics Holdings, Inc.Directoras of Feb 21, 2024
- LIANY LianBioDirector, 10% Owneras of Feb 20, 2024
- ATXS Astria Therapeutics, Inc.Directoras of Feb 5, 2024
- VRCA Verrica Pharmaceuticals Inc.10% Owneras of Dec 29, 2023
- CRGX CARGO Therapeutics, Inc.Other: Former 10% Owneras of Nov 14, 2023
- SLNO Soleno Therapeutics Inc10% Owneras of Sep 28, 2023
- VBIV VBI Vaccines Inc/BC10% Owneras of Apr 6, 2023
- LABP Landos Biopharma, Inc.10% Owneras of Jan 11, 2023
- QTNT Quotient Ltd10% Owneras of Nov 2, 2022
- ALBO Albireo Pharma, Inc.10% Owneras of Oct 13, 2022
- CRNX Crinetics Pharmaceuticals, Inc.10% Owneras of Apr 18, 2022
- AGRX Agile Therapeutics Inc10% Owneras of Oct 15, 2021
- ISO IsoPlexis Corp10% Owneras of Oct 14, 2021
- Rain Oncology Inc.10% Owneras of Oct 13, 2021
- ADMA Adma Biologics, Inc.10% Owneras of Sep 30, 2021
- CYPH Cypherpunk Technologies Inc.10% Owneras of Sep 28, 2021
- YARW Yarrow Bioscience, Inc.10% Owneras of Aug 18, 2021
Open-market trades in the past year
Open-market purchases (P) and sales (S) filed in the last 365 days, not counting derivative securities or duplicate filings. Values leave out price outliers.
- Bought
- $7.50M
- 1 filing
- Sold
- $526.7K
- 2 filings
- Net
- +$6.97M
- Bought minus sold
- Companies
- 2
- With open-market trades
Trades
Every Form 4 that lists Perceptive Life Sciences Master Fund Ltd as a reporting owner, including filings made jointly with others, grouped by company. Each row adds up one type of transaction in one filing. Only open-market purchases (P) and sales (S) are shown by default.
IMTX Immatics N.V.
Director1 trade
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| Aug 27, 2026 (view filing)4:00 PM ET | Aug 26 | 1 day | Edelman Joseph and 2 othersDirector | PPurchase | +863.1K | $8.69 | +$7.50M | +8.3%11.2M after |
LYRA Lyra Therapeutics, Inc.
10% Owner5 trades
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| Nov 13, 2025 (view filing)5:07 PM ET | Nov 11-13 | 2 days | Edelman Joseph and 3 others10% Owner | SSale | −45.9K | $3.98 | −$182.5K | −76.6%14.0K after | 6 lots |
| Nov 10, 2025 (view filing)5:08 PM ET | Nov 6-10 | 4 days | Edelman Joseph and 3 others10% Owner | SSale | −70.4K | $4.89 | −$344.2K | −79.0%18.7K after | 6 lots |
| Jun 2, 2023 (view filing)4:11 PM ET | May 31 | 2 days | Edelman Joseph and 3 othersDirector, 10% Owner | PPurchase | +3.61M | $2.49 | +$9.00M | +45.9%11.5M after | |
| Jun 2, 2023 (view filing)4:11 PM ET | May 31 | 2 days | Edelman Joseph and 3 othersDirector, 10% Owner | PPurchase | +1.81M | – | – | –1.81M after | Derivative |
| Apr 14, 2022 (view filing)4:53 PM ET | Apr 12 | 2 days | Edelman Joseph and 3 othersDirector, 10% Owner | PPurchase | +5.92M | $4.22 | +$25.0M | +306.3%7.86M after |
ADGM Adagio Medical Holdings, Inc.
10% Owner2 trades
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| Oct 22, 2025 (view filing)4:33 PM ET | Oct 20 | 2 days | Perceptive Advisors LLC and 2 othersDirector, 10% Owner | PPurchaseCommon Stock or Pre-Funded Warrants | +4.03M | $0.1846 | +$744.9K | –1.34M after | Derivative3 lots |
| Oct 22, 2025 (view filing)4:33 PM ET | Oct 20 | 2 days | Perceptive Advisors LLC and 2 othersDirector, 10% Owner | PPurchase | +2.19M | $1.60 | +$3.51M | –2.19M after | Derivative |
OBIO Orchestra BioMed Holdings, Inc.
10% Owner2 trades
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| Aug 5, 2025 (view filing)10:46 AM ET | Aug 1 | 4 days | Edelman Joseph and 2 others10% Owner | PPurchase | +700.0K | $2.75 | +$1.93M | +15.2%5.29M after | |
| Aug 5, 2025 (view filing)10:46 AM ET | Aug 1 | 4 days | Edelman Joseph and 2 others10% Owner | PPurchase | +1.50M | $2.75 | +$4.12M | –1.50M after | Derivative |
ACRV Acrivon Therapeutics, Inc.
10% Owner3 trades
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| May 1, 2025 (view filing)7:07 PM ET | Apr 30-May 1 | 1 day | Edelman Joseph and 2 others10% Owner | SSale | −736.8K | $1.38 | −$1.02M | −19.2%3.10M after | 2 lots |
| Apr 29, 2025 (view filing)7:26 PM ET | Apr 25-29 | 4 days | Edelman Joseph and 2 others10% Owner | SSale | −1.52M | $1.81 | −$2.74M | −28.4%3.84M after | 3 lots |
| Apr 15, 2024 (view filing)8:53 AM ET | Apr 11 | 4 days | Edelman Joseph and 2 others10% Owner | PPurchase | +2.35M | $8.50 | +$20.0M | +78.2%5.36M after |
ALDX Aldeyra Therapeutics, Inc.
10% Owner13 trades
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| Apr 7, 2025 (view filing)6:43 PM ET | Apr 3 | 4 days | Edelman Joseph and 2 others10% Owner | SSale | −3.40M | $1.42 | −$4.83M | −36.7%5.88M after | |
| Apr 8, 2024 (view filing)5:32 PM ET | Apr 4-5 | 4 days | Edelman Joseph and 2 others10% Owner | PPurchase | +178.0K | $4.68 | +$833.9K | +2.0%9.28M after | 2 lots |
| Apr 3, 2024 (view filing)5:22 PM ET | Apr 1-3 | 2 days | Edelman Joseph and 2 others10% Owner | PPurchase | +504.3K | $3.84 | +$1.93M | +5.9%9.10M after | 3 lots |
| Oct 18, 2023 (view filing)5:15 PM ET | Oct 16-18 | 2 days | Edelman Joseph and 2 others10% Owner | SSale | −2.76M | $1.62 | −$4.45M | −24.3%8.59M after | 2 lots |
| Aug 11, 2022 (view filing)4:08 PM ET | Aug 9-10 | 2 days | Edelman Joseph and 2 others10% Owner | PPurchase | +115.0K | $7.55 | +$867.8K | +1.0%11.4M after | 2 lots |
| Aug 10, 2022 (view filing)4:10 PM ET | Aug 8 | 2 days | Edelman Joseph and 2 others10% Owner | PPurchase | +97.0K | $7.24 | +$702.3K | +0.9%11.2M after | |
| Aug 9, 2022 (view filing)4:08 PM ET | Aug 5 | 4 days | Edelman Joseph and 2 others10% Owner | PPurchase | +141.0K | $6.95 | +$980.0K | +1.3%11.1M after | |
| Aug 8, 2022 (view filing)4:09 PM ET | Aug 4 | 4 days | Edelman Joseph and 2 others10% Owner | PPurchase | +95.1K | $6.17 | +$586.8K | +0.9%11.0M after | |
| Aug 5, 2022 (view filing)4:10 PM ET | Aug 3 | 2 days | Edelman Joseph and 2 others10% Owner | PPurchase | +100.0K | $5.84 | +$584.0K | +0.9%10.9M after | |
| Aug 4, 2022 (view filing)4:10 PM ET | Aug 2 | 2 days | Edelman Joseph and 2 others10% Owner | PPurchase | +412.4K | $5.59 | +$2.31M | +4.0%10.8M after |
SLDB Solid Biosciences Inc.
Director, 10% Owner2 trades
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| Feb 21, 2025 (view filing)4:17 PM ET | Feb 19 | 2 days | Edelman Joseph and 3 othersDirector, 10% Owner | PPurchase | +5.00M | $4.03 | +$20.1M | +73.2%11.8M after | |
| Jan 12, 2024 (view filing)5:15 PM ET | Jan 11 | 1 day | Edelman Joseph and 3 othersDirector, 10% Owner | PPurchase | +3.41M | $5.53 | +$18.9M | +99.6%6.83M after |
MGTX MeiraGTx Holdings plc
Director, 10% Owner2 trades
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| Aug 14, 2024 (view filing)6:54 PM ET | Aug 12 | 2 days | Edelman Joseph and 2 othersDirector, 10% Owner | PPurchase | +1.25M | $4.00 | +$5.00M | +11.1%12.5M after | |
| May 15, 2023 (view filing)8:12 PM ET | May 5 | 10 daysLate | Perceptive Advisors LLC and 2 othersDirector, 10% Owner | PPurchase | +4.35M | $5.75 | +$25.0M | +62.7%11.3M after |
ATXS Astria Therapeutics, Inc.
Director5 trades
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| Feb 5, 2024 (view filing)5:02 PM ET | Feb 1 | 4 days | Edelman Joseph and 3 othersDirector | PPurchase | +2.48M | $12.09 | +$30.0M | +103.7%4.87M after | |
| Dec 22, 2023 (view filing)2:51 PM ET | Dec 21 | 1 day | Edelman Joseph and 3 othersDirector | PPurchase | +740.0K | $6.20 | +$4.59M | +44.8%2.39M after | |
| Oct 18, 2023 (view filing)4:11 PM ET | Oct 16 | 2 days | Edelman Joseph and 3 othersDirector | PPurchase | +1.07M | $6.51 | +$7.00M | +200.1%1.61M after | 2 lots |
| Oct 18, 2023 (view filing)4:11 PM ET | Oct 16 | 2 days | Edelman Joseph and 3 othersDirector | PPurchase | +2.42M | $7.86 | +$19.0M | –345.4K after | Derivative4 lots |
| Dec 21, 2022 (view filing)4:52 PM ET | Dec 19 | 2 days | Edelman Joseph and 3 othersDirector | PPurchase | +908.3K | $11.01 | +$10.0M | +698.4%1.04M after |
VRCA Verrica Pharmaceuticals Inc.
10% Owner4 trades
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| Dec 29, 2023 (view filing)5:27 PM ET | Dec 27-29 | 2 days | Edelman Joseph and 2 others10% Owner | PPurchase | +321.6K | $7.17 | +$2.31M | +4.7%7.10M after | 3 lots |
| Dec 26, 2023 (view filing)7:21 PM ET | Dec 21-26 | 5 days | Edelman Joseph and 2 others10% Owner | PPurchase | +504.7K | $6.45 | +$3.26M | +8.0%6.78M after | 3 lots |
| Dec 19, 2023 (view filing)5:52 PM ET | Dec 15-19 | 4 days | Edelman Joseph and 2 others10% Owner | PPurchase | +1.23M | $5.63 | +$6.94M | +24.5%6.27M after | 3 lots |
| Jul 5, 2022 (view filing)5:32 PM ET | Jul 5 | Same day | Edelman Joseph and 2 others10% Owner | PPurchase | +1.43M | $2.10 | +$3.00M | +39.6%5.04M after |
LONA LeonaBio, Inc.
Director, 10% Owner2 trades
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| Dec 29, 2023 (view filing)5:24 PM ET | Dec 27-29 | 2 days | Edelman Joseph and 2 othersDirector, 10% Owner | PPurchase | +605.7K | $2.42 | +$1.46M | +12.6%5.40M after | 3 lots |
| Jul 1, 2022 (view filing)2:24 PM ET | Jun 29-30 | 2 days | Edelman Joseph and 2 othersDirector, 10% Owner | PPurchase | +1.37M | $2.99 | +$4.10M | +40.0%4.80M after | 2 lots |
CRGX CARGO Therapeutics, Inc.
Other: Former 10% Owner1 trade
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| Nov 14, 2023 (view filing)4:32 PM ET | Nov 14 | Same day | Edelman Joseph and 3 othersOther: Former 10% Owner | PPurchase | +666.7K | $15.00 | +$10.0M | New position333.3K after | 2 lots |
CERE Cerevel Therapeutics Holdings, Inc.
Director6 trades
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| Oct 17, 2023 (view filing)4:53 PM ET | Oct 16 | 1 day | Edelman Joseph and 2 othersDirector | PPurchase | +876.8K | $22.81 | +$20.0M | +8.8%10.8M after | |
| Aug 18, 2022 (view filing)5:10 PM ET | Aug 16 | 2 days | Edelman Joseph and 2 othersDirector | PPurchase | +1.43M | $35.00 | +$49.9M | +28.0%6.51M after | |
| Aug 18, 2022 (view filing)5:10 PM ET | Aug 16 | 2 days | Edelman Joseph and 2 othersDirector | PPurchase | +2.16M | – | – | – | DerivativePrice outlier |
| Aug 31, 2021 (view filing)2:15 PM ET | Aug 26 | 5 daysLate | Edelman Joseph and 2 othersDirector | PPurchase | +68.0K | $30.23 | +$2.06M | +1.4%5.09M after | |
| Aug 25, 2021 (view filing)7:14 PM ET | Aug 23-25 | 2 days | Edelman Joseph and 2 othersDirector | PPurchase | +175.6K | $27.53 | +$4.83M | +3.6%5.02M after | 3 lots |
| Jul 9, 2021 (view filing)6:39 PM ET | Jul 7 | 2 days | Edelman Joseph and 2 othersDirector | PPurchase | +200.0K | $25.00 | +$5.00M | +4.3%4.84M after |
SLNO Soleno Therapeutics Inc
10% Owner6 trades
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| Sep 28, 2023 (view filing)3:45 PM ET | Sep 26-28 | 2 days | Edelman Joseph and 2 others10% Owner | PPurchase | +866.8K | $17.44 | +$15.1M | +39.3%3.07M after | 15 lots |
| Sep 28, 2023 (view filing)3:45 PM ET | Sep 28 | Same day | Edelman Joseph and 2 others10% Owner | PPurchase | +250.0K | $19.99 | +$5.00M | –250.0K after | Derivative |
| Jun 6, 2023 (view filing)4:16 PM ET | Jun 2-6 | 4 days | Edelman Joseph and 2 others10% Owner | PPurchase | +143.3K | $5.96 | +$853.7K | +6.9%2.21M after | 3 lots |
| Jun 1, 2023 (view filing)5:41 PM ET | May 30-Jun 1 | 2 days | Edelman Joseph and 2 others10% Owner | PPurchase | +35.0K | $5.38 | +$188.2K | +1.7%2.06M after | 3 lots |
| May 26, 2023 (view filing)5:57 PM ET | May 24-26 | 2 days | Edelman Joseph and 2 others10% Owner | PPurchase210859 | +85.0K | $5.29 | +$449.8K | +4.4%2.03M after | 3 lots |
| May 23, 2023 (view filing)6:47 PM ET | May 19-23 | 4 days | Edelman Joseph and 2 others10% Owner | PPurchase | +80.0K | $5.08 | +$406.1K | +4.3%1.94M after | 3 lots |
VBIV VBI Vaccines Inc/BC
10% Owner2 trades
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| Apr 6, 2023 (view filing)5:51 PM ET | Apr 4-6 | 2 days | Edelman Joseph and 2 others10% Owner | SSale | −10.9M | $0.1354 | −$1.48M | −20.8%41.4M after | 3 lots |
| Dec 3, 2021 (view filing)6:22 PM ET | Dec 1 | 2 days | Edelman Joseph and 2 others10% Owner | SSale | −2.71M | $3.31 | −$8.96M | −4.9%52.3M after |
LABP Landos Biopharma, Inc.
10% Owner1 trade
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| Jan 11, 2023 (view filing)6:45 PM ET | Jan 10 | 1 day | Edelman Joseph and 4 others10% Owner | PPurchase | +30.9M | $0.54 | +$16.7M | –3.64M after | Derivative2 lots |
QTNT Quotient Ltd
10% Owner1 trade
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| Nov 2, 2022 (view filing)4:58 PM ET | Oct 31 | 2 days | Edelman Joseph and 2 others10% Owner | SSaleOrdinary Shares, nil par value | −8.26M | $0.08 | −$660.4K | −51.0%7.95M after |
ALBO Albireo Pharma, Inc.
10% Owner1 trade
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| Oct 13, 2022 (view filing)7:37 PM ET | Oct 11-13 | 2 days | Edelman Joseph and 2 others10% Owner | SSale | −420.4K | $22.61 | −$9.51M | −17.8%1.94M after | 7 lots |
LIANY LianBio
Director, 10% Owner5 trades
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| Aug 22, 2022 (view filing)9:17 AM ET | Aug 18 | 4 days | Edelman Joseph and 7 othersDirector, 10% Owner | PPurchaseAmerican Depositary Shares | +998.2K | $2.40 | +$2.40M | +36.6%3.73M after | |
| May 27, 2022 (view filing)10:06 AM ET | May 26 | 1 day | Edelman Joseph and 7 othersDirector, 10% Owner | PPurchaseAmerican Depositary Shares | +69.0K | $3.13 | +$216.0K | +2.6%2.73M after | |
| May 25, 2022 (view filing)6:51 PM ET | May 23-25 | 2 days | Edelman Joseph and 7 othersDirector, 10% Owner | PPurchaseAmerican Depositary Shares | +171.3K | $2.58 | +$442.4K | +6.9%2.66M after | 3 lots |
| Nov 5, 2021 (view filing)1:47 PM ET | Nov 3 | 2 days | Edelman Joseph and 7 othersDirector, 10% Owner | PPurchase | +2.27M | $15.98 | +$36.3M | +8.9%27.9M after | 2 lots |
| Nov 3, 2021 (view filing)6:59 PM ET | Nov 1-2 | 2 days | Perceptive Advisors LLC and 7 othersDirector, 10% Owner | PPurchase | +220.0K | $14.59 | +$3.21M | +3.1%7.25M after | 2 lots |
CRNX Crinetics Pharmaceuticals, Inc.
10% Owner2 trades
| Filed (ET) | Trade date | Filing delay | Insider | Transaction | Shares | Avg price | Value | Holding change | Flags |
|---|---|---|---|---|---|---|---|---|---|
| Apr 18, 2022 (view filing)5:39 PM ET | Apr 18 | Same day | Edelman Joseph and 2 others10% Owner | PPurchase | +157.5K | $22.22 | +$3.50M | +3.1%5.32M after | |
| Oct 25, 2021 (view filing)2:47 PM ET | Oct 25 | Same day | Edelman Joseph and 2 others10% Owner | PPurchase | +1.20M | $19.80 | +$23.8M | +30.3%5.16M after |