Lyra Therapeutics, Inc.
LYRADelisted Apr 20, 2026- Industry
- Surgical & Medical Instruments & Apparatus
- SEC CIK
- 0001327273
Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.
13F holders, Q4 2025
Institutional positions in Lyra Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
LYRA is no longer listed, so this page shows Q4 2025. 13F filings for later quarters list far fewer holders.
- Institutional holders
- 23
- −3 vs. Q3 2025
- Shares held
- 242.6K
- −206.0K (−45.9%) vs. Q3 2025
- Total value
- $747.3K
- −$2.19M (−74.5%) vs. Q3 2025
- New holders
- 3
- 6 more added
- Sold out
- 6
- 6 more reduced
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 1 | $51.1K |
| Q4 2025 | 23 | $747.3K |
| Q3 2025 | 26 | $2.93M |
| Q2 2025 | 30 | $4.42M |
| Q1 2025 | 57 | $3.23M |
| Q4 2024 | 54 | $5.54M |
| Q3 2024 | 62 | $8.36M |
| Q2 2024 | 51 | $9.06M |
| Q1 2024 | 79 | $283.4M |
| Q4 2023 | 60 | $222.0M |
| Q3 2023 | 45 | $124.8M |
| Q2 2023 | 39 | $138.4M |
| Q1 2023 | 31 | $38.1M |
| Q4 2022 | 37 | $59.9M |
| Q3 2022 | 38 | $96.0M |
| Q2 2022 | 38 | $108.9M |
| Q1 2022 | 28 | $20.2M |
| Q4 2021 | 34 | $22.4M |
| Q3 2021 | 37 | $60.8M |
| Q2 2021 | 46 | $56.0M |
| Q1 2021 | 50 | $87.6M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Sabby Management, LLC | 175,158 | $539.5K | 4.50% | +47,534+37.2% | Added |
| Ikarian Capital, LLC | 21,161 | $65.2K | 0.01% | 00.0% | Unchanged |
| DRW Securities, LLC | 16,812 | $51.8K | 0.00% | +16,812 | New |
| Geode Capital Management, LLC | 12,249 | $37.7K | 0.00% | +1,263+11.5% | Added |
| Artia Global Partners LP | 8,756 | $27.0K | 0.00% | +8,756 | New |
| BlackRock, Inc. | 2,394 | $7.37K | 0.00% | +704+41.7% | Added |
| Tower Research Capital LLC (TRC) | 2,191 | $6.75K | 0.00% | +1,657+310.3% | Added |
| Royal Bank of Canada | 1,953 | $6.00K | 0.00% | +628+47.4% | Added |
| UBS Group AG | 675 | $2.08K | 0.00% | −3,326−83.1% | Reduced |
| EverSource Wealth Advisors, LLC | 338 | $1.04K | 0.00% | −7−2.0% | Reduced |
| Morgan Stanley | 334 | $1.03K | 0.00% | −943−73.8% | Reduced |
| Jones Financial Companies LLLP | 210 | $647 | 0.00% | 00.0% | Unchanged |
| Bank of America Corp | 201 | $619 | 0.00% | +183+1,016.7% | Added |
| SBI Securities Co., Ltd. | 80 | $246 | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 27 | $83 | 0.00% | 00.0% | Unchanged |
| Comerica Bank | 23 | $71 | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 22 | $67 | 0.00% | 00.0% | Unchanged |
| Bryn Mawr Trust Co | 20 | $62 | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 16 | $49 | 0.00% | 00.0% | Unchanged |
| Global Retirement Partners, LLC | 15 | $46 | 0.00% | +15 | New |
| Citigroup Inc | 3 | $9 | 0.00% | −702−99.6% | Reduced |
| IFP Advisors, Inc | 1 | $3 | 0.00% | −1−50.0% | Reduced |
| CWM, LLC | 1 | $0 | 0.00% | −23−95.8% | Reduced |
| Perceptive Advisors LLC | 0 | $0 | 0.00% | −229,382−100.0% | Sold out |
| Vanguard Group Inc | 0 | $0 | 0.00% | −28,754−100.0% | Sold out |
| Citadel Advisors LLC | 0 | $0 | 0.00% | −19,484−100.0% | Sold out |
| FMR LLC | 0 | $0 | 0.00% | −406−100.0% | Sold out |
| Signature Resources Capital Management, LLC | 0 | $0 | 0.00% | −400−100.0% | Sold out |
| Fortitude Family Office, LLC | 0 | $0 | 0.00% | −96−100.0% | Sold out |