Lyra Therapeutics, Inc.
LYRADelisted Apr 20, 2026- Industry
- Surgical & Medical Instruments & Apparatus
- SEC CIK
- 0001327273
Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.
13F holders, Q1 2023
Institutional positions in Lyra Therapeutics, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 31
- −5 vs. Q4 2022
- Shares held
- 18.9M
- −148.4K (−0.8%) vs. Q4 2022
- Total value
- $38.1M
- −$21.8M (−36.4%) vs. Q4 2022
- New holders
- 2
- 5 more added
- Sold out
- 7
- 4 more reduced
1 institution that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 1 | $51.1K |
| Q4 2025 | 23 | $747.3K |
| Q3 2025 | 26 | $2.93M |
| Q2 2025 | 30 | $4.42M |
| Q1 2025 | 57 | $3.23M |
| Q4 2024 | 54 | $5.54M |
| Q3 2024 | 62 | $8.36M |
| Q2 2024 | 51 | $9.06M |
| Q1 2024 | 79 | $283.4M |
| Q4 2023 | 60 | $222.0M |
| Q3 2023 | 45 | $124.8M |
| Q2 2023 | 39 | $138.4M |
| Q1 2023 | 31 | $38.1M |
| Q4 2022 | 37 | $59.9M |
| Q3 2022 | 38 | $96.0M |
| Q2 2022 | 38 | $108.9M |
| Q1 2022 | 28 | $20.2M |
| Q4 2021 | 34 | $22.4M |
| Q3 2021 | 37 | $60.8M |
| Q2 2021 | 46 | $56.0M |
| Q1 2021 | 50 | $87.6M |
Institutions, Q1 2023
Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc.; share changes are against Q4 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Perceptive Advisors LLC | 9,146,730 | $18.4M | 0.54% | 00.0% | Unchanged |
| Nantahala Capital Management, LLC | 2,220,830 | $4.46M | 0.43% | 00.0% | Unchanged |
| Pura Vida Investments, LLC | 1,996,972 | $4.01M | 0.41% | −160,326−7.4% | Reduced |
| Samsara BioCapital, LLC | 1,777,251 | $3.57M | 0.74% | 00.0% | Unchanged |
| VR Adviser, LLC | 924,170 | $1.86M | 0.36% | 00.0% | Unchanged |
| Vanguard Group Inc | 790,936 | $1.59M | 0.00% | 00.0% | Unchanged |
| Soleus Capital Management, L.P. | 592,417 | $1.19M | 0.15% | 00.0% | Unchanged |
| Ikarian Capital, LLC | 343,685 | $711.4K | 0.30% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 302,235 | $625.6K | 0.00% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 148,840 | $308.1K | 0.00% | 00.0% | Unchanged |
| Bridgeway Capital Management, LLC | 146,800 | $303.9K | 0.01% | 00.0% | Unchanged |
| Clearline Capital LP | 119,128 | $239.4K | 0.04% | 00.0% | Unchanged |
| Bank of America Corp | 104,768 | $210.6K | 0.00% | +3,014+3.0% | Added |
| Millennium Management LLC | 58,092 | $120.0K | 0.00% | +58,092 | New |
| Renaissance Technologies LLC | 47,851 | $96.0K | 0.00% | +10,651+28.6% | Added |
| BlackRock Inc. | 41,380 | $83.2K | 0.00% | +1,266+3.2% | Added |
| State Street Corp | 37,580 | $77.8K | 0.00% | 00.0% | Unchanged |
| Boothbay Fund Management, LLC | 34,721 | $69.8K | 0.00% | 00.0% | Unchanged |
| Northern Trust Corp | 29,829 | $60.0K | 0.00% | 00.0% | Unchanged |
| Two Sigma Advisers, LP | 28,300 | $56.9K | 0.00% | −300−1.0% | Reduced |
| Squarepoint Ops LLC | 11,280 | $23.4K | 0.00% | +11,280 | New |
| Tower Research Capital LLC (TRC) | 9,972 | $20.0K | 0.00% | +5,186+108.4% | Added |
| Citadel Advisors LLC | 7,934 | $16.4K | 0.00% | −17,343−68.6% | Reduced |
| UBS Group AG | 853 | $1.71K | 0.00% | −2,544−74.9% | Reduced |
| Ameliora Wealth Management Ltd. | 750 | $1.55K | 0.00% | 00.0% | Unchanged |
| Worth Asset Management, LLC | 650 | $1.31K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 500 | $1.00K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 500 | $1.00K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 500 | $1.00K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 114 | $229 | 0.00% | +1+0.9% | Added |
| JPMorgan Chase & Co | 34 | $0 | 0.00% | 00.0% | Unchanged |
| Anson Funds Management LP | 0 | $0 | 0.00% | −39,127−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −13,582−100.0% | Sold out |
| Belpointe Asset Management LLC | 0 | $0 | 0.00% | −3,703−100.0% | Sold out |
| Royal Bank of Canada | 0 | $0 | 0.00% | −491−100.0% | Sold out |
| FMR LLC | 0 | $0 | 0.00% | −450−100.0% | Sold out |
| Investors Research Corp | 0 | $0 | 0.00% | −15−100.0% | Sold out |
| Morgan Stanley | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| CoreCap Advisors, LLC | – | – | – | – | Not filed |