Lyra Therapeutics, Inc.
LYRADelisted Apr 20, 2026- Industry
- Surgical & Medical Instruments & Apparatus
- SEC CIK
- 0001327273
Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.
13F holders, Q1 2022
Institutional positions in Lyra Therapeutics, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 28
- −6 vs. Q4 2021
- Shares held
- 5.02M
- −110.8K (−2.2%) vs. Q4 2021
- Total value
- $20.2M
- −$2.19M (−9.8%) vs. Q4 2021
- New holders
- 2
- 6 more added
- Sold out
- 8
- 8 more reduced
Compare with Q4 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 1 | $51.1K |
| Q4 2025 | 23 | $747.3K |
| Q3 2025 | 26 | $2.93M |
| Q2 2025 | 30 | $4.42M |
| Q1 2025 | 57 | $3.23M |
| Q4 2024 | 54 | $5.54M |
| Q3 2024 | 62 | $8.36M |
| Q2 2024 | 51 | $9.06M |
| Q1 2024 | 79 | $283.4M |
| Q4 2023 | 60 | $222.0M |
| Q3 2023 | 45 | $124.8M |
| Q2 2023 | 39 | $138.4M |
| Q1 2023 | 31 | $38.1M |
| Q4 2022 | 37 | $59.9M |
| Q3 2022 | 38 | $96.0M |
| Q2 2022 | 38 | $108.9M |
| Q1 2022 | 28 | $20.2M |
| Q4 2021 | 34 | $22.4M |
| Q3 2021 | 37 | $60.8M |
| Q2 2021 | 46 | $56.0M |
| Q1 2021 | 50 | $87.6M |
Institutions, Q1 2022
Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc.; share changes are against Q4 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Perceptive Advisors LLC | 3,222,560 | $13.0M | 0.27% | 00.0% | Unchanged |
| Pura Vida Investments, LLC | 520,544 | $2.09M | 0.25% | +3,300+0.6% | Added |
| Ikarian Capital, LLC | 422,338 | $1.70M | 0.52% | +27,802+7.0% | Added |
| Vanguard Group Inc | 218,753 | $879.0K | 0.00% | 00.0% | Unchanged |
| Clearline Capital LP | 119,924 | $482.0K | 0.07% | +55,062+84.9% | Added |
| Millennium Management LLC | 112,707 | $453.0K | 0.00% | −40,227−26.3% | Reduced |
| Bank of America Corp | 82,200 | $330.0K | 0.00% | −1,640−2.0% | Reduced |
| Bridgeway Capital Management, LLC | 66,900 | $269.0K | 0.01% | 00.0% | Unchanged |
| Pentwater Capital Management LP | 60,000 | $241.0K | 0.00% | −11,313−15.9% | Reduced |
| Ensign Peak Advisors, Inc | 39,167 | $157.0K | 0.00% | 00.0% | Unchanged |
| Boothbay Fund Management, LLC | 38,516 | $155.0K | 0.01% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 37,464 | $150.0K | 0.00% | +1,446+4.0% | Added |
| Two Sigma Advisers, LP | 20,000 | $80.0K | 0.00% | −36,700−64.7% | Reduced |
| BlackRock Inc. | 19,006 | $77.0K | 0.00% | +733+4.0% | Added |
| Renaissance Technologies LLC | 17,500 | $70.0K | 0.00% | −34,500−66.3% | Reduced |
| Morgan Stanley | 8,085 | $33.0K | 0.00% | −1,346−14.3% | Reduced |
| JPMorgan Chase & Co | 7,759 | $31.0K | 0.00% | +6,910+813.9% | Added |
| Close Asset Management Ltd | 7,000 | $30.0K | 0.00% | 00.0% | Unchanged |
| Worth Asset Management, LLC | 650 | $3.00K | 0.00% | +650 | New |
| Advisor Group Holdings, Inc. | 500 | $2.00K | 0.00% | −734−59.5% | Reduced |
| US Bancorp | 500 | $2.00K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 537 | $2.00K | 0.00% | 00.0% | Unchanged |
| Laurel Wealth Advisors LLC | 500 | $2.00K | 0.00% | 00.0% | Unchanged |
| TD Waterhouse Canada Inc. | 200 | $830 | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 18 | $0 | 0.00% | −4,052−99.6% | Reduced |
| Royal Bank of Canada | 77 | $0 | 0.00% | 00.0% | Unchanged |
| Investors Research Corp | 15 | $0 | 0.00% | 00.0% | Unchanged |
| Prospera Financial Services Inc | 100 | $0 | 0.00% | +100 | New |
| Two Sigma Investments, LP | 0 | $0 | 0.00% | −17,731−100.0% | Sold out |
| Citadel Advisors LLC | 0 | $0 | 0.00% | −13,252−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −13,127−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −11,200−100.0% | Sold out |
| Tower Research Capital LLC (TRC) | 0 | $0 | 0.00% | −10,655−100.0% | Sold out |
| Soleus Capital Management, L.P. | 0 | $0 | 0.00% | −10,000−100.0% | Sold out |
| CoreCap Advisors, LLC | 0 | $0 | 0.00% | −125−100.0% | Sold out |
| Koshinski Asset Management, Inc. | 0 | $0 | 0.00% | −200−100.0% | Sold out |