Lyra Therapeutics, Inc.
LYRADelisted Apr 20, 2026- Industry
- Surgical & Medical Instruments & Apparatus
- SEC CIK
- 0001327273
Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.
13F holders, Q4 2021
Institutional positions in Lyra Therapeutics, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 34
- −2 vs. Q3 2021
- Shares held
- 5.13M
- −432.0K (−7.8%) vs. Q3 2021
- Total value
- $22.4M
- −$28.4M (−55.9%) vs. Q3 2021
- New holders
- 6
- 7 more added
- Sold out
- 8
- 11 more reduced
1 institution that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 1 | $51.1K |
| Q4 2025 | 23 | $747.3K |
| Q3 2025 | 26 | $2.93M |
| Q2 2025 | 30 | $4.42M |
| Q1 2025 | 57 | $3.23M |
| Q4 2024 | 54 | $5.54M |
| Q3 2024 | 62 | $8.36M |
| Q2 2024 | 51 | $9.06M |
| Q1 2024 | 79 | $283.4M |
| Q4 2023 | 60 | $222.0M |
| Q3 2023 | 45 | $124.8M |
| Q2 2023 | 39 | $138.4M |
| Q1 2023 | 31 | $38.1M |
| Q4 2022 | 37 | $59.9M |
| Q3 2022 | 38 | $96.0M |
| Q2 2022 | 38 | $108.9M |
| Q1 2022 | 28 | $20.2M |
| Q4 2021 | 34 | $22.4M |
| Q3 2021 | 37 | $60.8M |
| Q2 2021 | 46 | $56.0M |
| Q1 2021 | 50 | $87.6M |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc.; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Perceptive Advisors LLC | 3,222,560 | $14.1M | 0.22% | 00.0% | Unchanged |
| Pura Vida Investments, LLC | 517,244 | $2.25M | 0.24% | −16,173−3.0% | Reduced |
| Ikarian Capital, LLC | 394,536 | $1.72M | 0.49% | −8,914−2.2% | Reduced |
| Vanguard Group Inc | 218,753 | $954.0K | 0.00% | −1,276−0.6% | Reduced |
| Millennium Management LLC | 152,934 | $667.0K | 0.00% | +34,776+29.4% | Added |
| Bank of America Corp | 83,840 | $366.0K | 0.00% | −26,671−24.1% | Reduced |
| Pentwater Capital Management LP | 71,313 | $311.0K | 0.00% | +39,299+122.8% | Added |
| Bridgeway Capital Management, LLC | 66,900 | $292.0K | 0.01% | −2,000−2.9% | Reduced |
| Clearline Capital LP | 64,862 | $283.0K | 0.04% | +64,862 | New |
| Two Sigma Advisers, LP | 56,700 | $247.0K | 0.00% | −1,300−2.2% | Reduced |
| Renaissance Technologies LLC | 52,000 | $227.0K | 0.00% | +52,000 | New |
| Ensign Peak Advisors, Inc | 39,167 | $171.0K | 0.00% | 00.0% | Unchanged |
| Boothbay Fund Management, LLC | 38,516 | $168.0K | 0.01% | −684−1.7% | Reduced |
| Geode Capital Management, LLC | 36,018 | $157.0K | 0.00% | 00.0% | Unchanged |
| BlackRock Inc. | 18,273 | $80.0K | 0.00% | +455+2.6% | Added |
| Two Sigma Investments, LP | 17,731 | $77.0K | 0.00% | +4,347+32.5% | Added |
| Citadel Advisors LLC | 13,252 | $58.0K | 0.00% | +13,252 | New |
| Virtu Financial LLC | 13,127 | $57.0K | 0.01% | +13,127 | New |
| Susquehanna International Group, LLP | 11,200 | $49.0K | 0.00% | −4,695−29.5% | Reduced |
| Tower Research Capital LLC (TRC) | 10,655 | $47.0K | 0.00% | +6,420+151.6% | Added |
| Soleus Capital Management, L.P. | 10,000 | $44.0K | 0.01% | −205,576−95.4% | Reduced |
| Morgan Stanley | 9,431 | $41.0K | 0.00% | −20,732−68.7% | Reduced |
| Close Asset Management Ltd | 7,000 | $30.0K | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 4,070 | $18.0K | 0.00% | +4,052+22,511.1% | Added |
| Advisor Group Holdings, Inc. | 1,234 | $5.00K | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 849 | $4.00K | 0.00% | +815+2,397.1% | Added |
| US Bancorp | 500 | $2.00K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 537 | $2.00K | 0.00% | 00.0% | Unchanged |
| Laurel Wealth Advisors LLC | 500 | $2.00K | 0.00% | 00.0% | Unchanged |
| CoreCap Advisors, LLC | 125 | $1.00K | 0.00% | +125 | New |
| Koshinski Asset Management, Inc. | 200 | $872 | 0.00% | 00.0% | Unchanged |
| TD Waterhouse Canada Inc. | 200 | $870 | 0.00% | +200 | New |
| Royal Bank of Canada | 77 | $0 | 0.00% | −210−73.2% | Reduced |
| Investors Research Corp | 15 | $0 | 0.00% | 00.0% | Unchanged |
| ArrowMark Colorado Holdings LLC | 0 | $0 | 0.00% | −139,187−100.0% | Sold out |
| Parian Global Management LP | 0 | $0 | 0.00% | −121,300−100.0% | Sold out |
| Deutsche Bank AG | 0 | $0 | 0.00% | −76,352−100.0% | Sold out |
| Ergoteles LLC | 0 | $0 | 0.00% | −16,273−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −12,457−100.0% | Sold out |
| Trexquant Investment LP | 0 | $0 | 0.00% | −11,085−100.0% | Sold out |
| Cardinal Capital Management, Inc. | 0 | $0 | 0.00% | −650−100.0% | Sold out |
| Harbour Investments, Inc. | 0 | $0 | 0.00% | −175−100.0% | Sold out |
| Polaris Venture Management Co. V, L.L.C. | – | – | – | – | Not filed |