Lyra Therapeutics, Inc.
LYRADelisted Apr 20, 2026- Industry
- Surgical & Medical Instruments & Apparatus
- SEC CIK
- 0001327273
Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.
13F holders, Q4 2021
Institutional positions in Lyra Therapeutics, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 34
- −2 vs. Q3 2021
- Shares held
- 5.13M
- −432.0K (−7.8%) vs. Q3 2021
- Total value
- $22.4M
- −$28.4M (−55.9%) vs. Q3 2021
- New holders
- 6
- 7 more added
- Sold out
- 8
- 11 more reduced
1 institution that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 1 | $51.1K |
| Q4 2025 | 23 | $747.3K |
| Q3 2025 | 26 | $2.93M |
| Q2 2025 | 30 | $4.42M |
| Q1 2025 | 57 | $3.23M |
| Q4 2024 | 54 | $5.54M |
| Q3 2024 | 62 | $8.36M |
| Q2 2024 | 51 | $9.06M |
| Q1 2024 | 79 | $283.4M |
| Q4 2023 | 60 | $222.0M |
| Q3 2023 | 45 | $124.8M |
| Q2 2023 | 39 | $138.4M |
| Q1 2023 | 31 | $38.1M |
| Q4 2022 | 37 | $59.9M |
| Q3 2022 | 38 | $96.0M |
| Q2 2022 | 38 | $108.9M |
| Q1 2022 | 28 | $20.2M |
| Q4 2021 | 34 | $22.4M |
| Q3 2021 | 37 | $60.8M |
| Q2 2021 | 46 | $56.0M |
| Q1 2021 | 50 | $87.6M |
Institutions, Q4 2021
Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc.; share changes are against Q3 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Royal Bank of Canada | 77 | $0 | 0.00% | −210−73.2% | Reduced |
| Investors Research Corp | 15 | $0 | 0.00% | 00.0% | Unchanged |
| TD Waterhouse Canada Inc. | 200 | $870 | 0.00% | +200 | New |
| Koshinski Asset Management, Inc. | 200 | $872 | 0.00% | 00.0% | Unchanged |
| CoreCap Advisors, LLC | 125 | $1.00K | 0.00% | +125 | New |
| US Bancorp | 500 | $2.00K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 537 | $2.00K | 0.00% | 00.0% | Unchanged |
| Laurel Wealth Advisors LLC | 500 | $2.00K | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 849 | $4.00K | 0.00% | +815+2,397.1% | Added |
| Advisor Group Holdings, Inc. | 1,234 | $5.00K | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 4,070 | $18.0K | 0.00% | +4,052+22,511.1% | Added |
| Close Asset Management Ltd | 7,000 | $30.0K | 0.00% | 00.0% | Unchanged |
| Morgan Stanley | 9,431 | $41.0K | 0.00% | −20,732−68.7% | Reduced |
| Soleus Capital Management, L.P. | 10,000 | $44.0K | 0.01% | −205,576−95.4% | Reduced |
| Tower Research Capital LLC (TRC) | 10,655 | $47.0K | 0.00% | +6,420+151.6% | Added |
| Susquehanna International Group, LLP | 11,200 | $49.0K | 0.00% | −4,695−29.5% | Reduced |
| Virtu Financial LLC | 13,127 | $57.0K | 0.01% | +13,127 | New |
| Citadel Advisors LLC | 13,252 | $58.0K | 0.00% | +13,252 | New |
| Two Sigma Investments, LP | 17,731 | $77.0K | 0.00% | +4,347+32.5% | Added |
| BlackRock Inc. | 18,273 | $80.0K | 0.00% | +455+2.6% | Added |
| Geode Capital Management, LLC | 36,018 | $157.0K | 0.00% | 00.0% | Unchanged |
| Boothbay Fund Management, LLC | 38,516 | $168.0K | 0.01% | −684−1.7% | Reduced |
| Ensign Peak Advisors, Inc | 39,167 | $171.0K | 0.00% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 52,000 | $227.0K | 0.00% | +52,000 | New |
| Two Sigma Advisers, LP | 56,700 | $247.0K | 0.00% | −1,300−2.2% | Reduced |
| Clearline Capital LP | 64,862 | $283.0K | 0.04% | +64,862 | New |
| Bridgeway Capital Management, LLC | 66,900 | $292.0K | 0.01% | −2,000−2.9% | Reduced |
| Pentwater Capital Management LP | 71,313 | $311.0K | 0.00% | +39,299+122.8% | Added |
| Bank of America Corp | 83,840 | $366.0K | 0.00% | −26,671−24.1% | Reduced |
| Millennium Management LLC | 152,934 | $667.0K | 0.00% | +34,776+29.4% | Added |
| Vanguard Group Inc | 218,753 | $954.0K | 0.00% | −1,276−0.6% | Reduced |
| Ikarian Capital, LLC | 394,536 | $1.72M | 0.49% | −8,914−2.2% | Reduced |
| Pura Vida Investments, LLC | 517,244 | $2.25M | 0.24% | −16,173−3.0% | Reduced |
| Perceptive Advisors LLC | 3,222,560 | $14.1M | 0.22% | 00.0% | Unchanged |
| ArrowMark Colorado Holdings LLC | 0 | $0 | 0.00% | −139,187−100.0% | Sold out |
| Parian Global Management LP | 0 | $0 | 0.00% | −121,300−100.0% | Sold out |
| Deutsche Bank AG | 0 | $0 | 0.00% | −76,352−100.0% | Sold out |
| Ergoteles LLC | 0 | $0 | 0.00% | −16,273−100.0% | Sold out |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −12,457−100.0% | Sold out |
| Trexquant Investment LP | 0 | $0 | 0.00% | −11,085−100.0% | Sold out |
| Cardinal Capital Management, Inc. | 0 | $0 | 0.00% | −650−100.0% | Sold out |
| Harbour Investments, Inc. | 0 | $0 | 0.00% | −175−100.0% | Sold out |
| Polaris Venture Management Co. V, L.L.C. | – | – | – | – | Not filed |