Lyra Therapeutics, Inc.
LYRADelisted Apr 20, 2026- Industry
- Surgical & Medical Instruments & Apparatus
- SEC CIK
- 0001327273
Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.
13F holders, Q3 2023
Institutional positions in Lyra Therapeutics, Inc. as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 45
- +6 vs. Q2 2023
- Shares held
- 31.9M
- −1.77M (−5.3%) vs. Q2 2023
- Total value
- $124.8M
- −$13.6M (−9.8%) vs. Q2 2023
- New holders
- 10
- 15 more added
- Sold out
- 4
- 7 more reduced
Compare with Q2 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 1 | $51.1K |
| Q4 2025 | 23 | $747.3K |
| Q3 2025 | 26 | $2.93M |
| Q2 2025 | 30 | $4.42M |
| Q1 2025 | 57 | $3.23M |
| Q4 2024 | 54 | $5.54M |
| Q3 2024 | 62 | $8.36M |
| Q2 2024 | 51 | $9.06M |
| Q1 2024 | 79 | $283.4M |
| Q4 2023 | 60 | $222.0M |
| Q3 2023 | 45 | $124.8M |
| Q2 2023 | 39 | $138.4M |
| Q1 2023 | 31 | $38.1M |
| Q4 2022 | 37 | $59.9M |
| Q3 2022 | 38 | $96.0M |
| Q2 2022 | 38 | $108.9M |
| Q1 2022 | 28 | $20.2M |
| Q4 2021 | 34 | $22.4M |
| Q3 2021 | 37 | $60.8M |
| Q2 2021 | 46 | $56.0M |
| Q1 2021 | 50 | $87.6M |
Institutions, Q3 2023
Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc.; share changes are against Q2 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Perceptive Advisors LLC | 12,757,562 | $49.9M | 1.68% | 00.0% | Unchanged |
| Nantahala Capital Management, LLC | 4,050,218 | $15.8M | 2.01% | +92,676+2.3% | Added |
| Citadel Advisors LLC | 2,848,564 | $11.1M | 0.01% | −6140.0% | Reduced |
| Samsara BioCapital, LLC | 2,780,261 | $10.9M | 3.33% | 00.0% | Unchanged |
| Armistice Capital, LLC | 1,550,000 | $6.06M | 0.18% | −2,462,036−61.4% | Reduced |
| Pura Vida Investments, LLC | 1,413,242 | $5.53M | 2.71% | 00.0% | Unchanged |
| Ikarian Capital, LLC | 1,254,384 | $4.90M | 1.82% | +275,758+28.2% | Added |
| VR Adviser, LLC | 924,170 | $3.61M | 0.38% | 00.0% | Unchanged |
| Vanguard Group Inc | 864,332 | $3.38M | 0.00% | +73,396+9.3% | Added |
| Parkman Healthcare Partners LLC | 625,056 | $2.44M | 0.45% | +25,056+4.2% | Added |
| Soleus Capital Management, L.P. | 592,417 | $2.32M | 0.23% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 308,690 | $1.21M | 0.00% | +159,850+107.4% | Added |
| Ensign Peak Advisors, Inc | 301,533 | $1.18M | 0.00% | −702−0.2% | Reduced |
| Millennium Management LLC | 263,349 | $1.03M | 0.00% | +263,349 | New |
| Boothbay Fund Management, LLC | 234,003 | $915.0K | 0.03% | +70,328+43.0% | Added |
| Susquehanna International Group, LLP | 162,860 | $636.8K | 0.00% | +150,975+1,270.3% | Added |
| Bridgeway Capital Management, LLC | 141,800 | $554.4K | 0.01% | +45,000+46.5% | Added |
| Alyeska Investment Group, L.P. | 130,839 | $511.6K | 0.00% | −350,607−72.8% | Reduced |
| Bank of America Corp | 125,954 | $492.5K | 0.00% | +13,140+11.6% | Added |
| Clearline Capital LP | 119,128 | $465.8K | 0.05% | 00.0% | Unchanged |
| State Street Corp | 95,080 | $371.8K | 0.00% | +39,300+70.5% | Added |
| Citigroup Inc | 67,677 | $264.6K | 0.00% | +67,677 | New |
| Northern Trust Corp | 57,009 | $222.9K | 0.00% | +27,296+91.9% | Added |
| Renaissance Technologies LLC | 49,800 | $195.0K | 0.00% | −21,200−29.9% | Reduced |
| BlackRock Inc. | 47,482 | $185.7K | 0.00% | −1,132−2.3% | Reduced |
| Letko, Brosseau & Associates Inc | 31,900 | $124.7K | 0.00% | 00.0% | Unchanged |
| Prescott Group Capital Management, L.L.C. | 30,000 | $117.0K | 0.03% | +30,000 | New |
| Dimensional Fund Advisors LP | 28,254 | $110.5K | 0.00% | +28,254 | New |
| Virtu Financial LLC | 19,618 | $77.0K | 0.01% | +19,618 | New |
| Bank of New York Mellon Corp | 18,621 | $72.8K | 0.00% | +18,621 | New |
| Two Sigma Investments, LP | 16,420 | $64.2K | 0.00% | +16,420 | New |
| Tower Research Capital LLC (TRC) | 6,762 | $26.4K | 0.00% | +5,320+368.9% | Added |
| Royal Bank of Canada | 3,271 | $13.0K | 0.00% | +3,197+4,320.3% | Added |
| Qube Research & Technologies Ltd | 3,282 | $12.8K | 0.00% | +3,282 | New |
| Advisor Group Holdings, Inc. | 1,500 | $5.87K | 0.00% | +206+15.9% | Added |
| Comerica Bank | 1,159 | $4.53K | 0.00% | +1,159 | New |
| Ameliora Wealth Management Ltd. | 750 | $2.92K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 500 | $1.96K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 500 | $1.96K | 0.00% | 00.0% | Unchanged |
| Rhumbline Advisers | 296 | $1.16K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 221 | $864 | 0.00% | +102+85.7% | Added |
| Group One Trading, L.P. | 200 | $782 | 0.00% | +200 | New |
| JPMorgan Chase & Co | 34 | $133 | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 18 | $70 | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 84 | $0 | 0.00% | −1,711−95.3% | Reduced |
| DAFNA Capital Management LLC | 0 | $0 | 0.00% | −361,084−100.0% | Sold out |
| Worth Asset Management, LLC | 0 | $0 | 0.00% | −650−100.0% | Sold out |
| Morgan Stanley | 0 | $0 | 0.00% | −510−100.0% | Sold out |
| FMR LLC | 0 | $0 | 0.00% | −11−100.0% | Sold out |