Lyra Therapeutics, Inc.
LYRADelisted Apr 20, 2026- Industry
- Surgical & Medical Instruments & Apparatus
- SEC CIK
- 0001327273
Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.
13F holders, Q3 2023
Institutional positions in Lyra Therapeutics, Inc. as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 45
- +6 vs. Q2 2023
- Shares held
- 31.9M
- −1.77M (−5.3%) vs. Q2 2023
- Total value
- $124.8M
- −$13.6M (−9.8%) vs. Q2 2023
- New holders
- 10
- 15 more added
- Sold out
- 4
- 7 more reduced
Compare with Q2 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 1 | $51.1K |
| Q4 2025 | 23 | $747.3K |
| Q3 2025 | 26 | $2.93M |
| Q2 2025 | 30 | $4.42M |
| Q1 2025 | 57 | $3.23M |
| Q4 2024 | 54 | $5.54M |
| Q3 2024 | 62 | $8.36M |
| Q2 2024 | 51 | $9.06M |
| Q1 2024 | 79 | $283.4M |
| Q4 2023 | 60 | $222.0M |
| Q3 2023 | 45 | $124.8M |
| Q2 2023 | 39 | $138.4M |
| Q1 2023 | 31 | $38.1M |
| Q4 2022 | 37 | $59.9M |
| Q3 2022 | 38 | $96.0M |
| Q2 2022 | 38 | $108.9M |
| Q1 2022 | 28 | $20.2M |
| Q4 2021 | 34 | $22.4M |
| Q3 2021 | 37 | $60.8M |
| Q2 2021 | 46 | $56.0M |
| Q1 2021 | 50 | $87.6M |
Institutions, Q3 2023
Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc.; share changes are against Q2 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Simplex Trading, LLC | 84 | $0 | 0.00% | −1,711−95.3% | Reduced |
| UBS Group AG | 18 | $70 | 0.00% | 00.0% | Unchanged |
| JPMorgan Chase & Co | 34 | $133 | 0.00% | 00.0% | Unchanged |
| Group One Trading, L.P. | 200 | $782 | 0.00% | +200 | New |
| Wells Fargo & Company | 221 | $864 | 0.00% | +102+85.7% | Added |
| Rhumbline Advisers | 296 | $1.16K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 500 | $1.96K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 500 | $1.96K | 0.00% | 00.0% | Unchanged |
| Ameliora Wealth Management Ltd. | 750 | $2.92K | 0.00% | 00.0% | Unchanged |
| Comerica Bank | 1,159 | $4.53K | 0.00% | +1,159 | New |
| Advisor Group Holdings, Inc. | 1,500 | $5.87K | 0.00% | +206+15.9% | Added |
| Qube Research & Technologies Ltd | 3,282 | $12.8K | 0.00% | +3,282 | New |
| Royal Bank of Canada | 3,271 | $13.0K | 0.00% | +3,197+4,320.3% | Added |
| Tower Research Capital LLC (TRC) | 6,762 | $26.4K | 0.00% | +5,320+368.9% | Added |
| Two Sigma Investments, LP | 16,420 | $64.2K | 0.00% | +16,420 | New |
| Bank of New York Mellon Corp | 18,621 | $72.8K | 0.00% | +18,621 | New |
| Virtu Financial LLC | 19,618 | $77.0K | 0.01% | +19,618 | New |
| Dimensional Fund Advisors LP | 28,254 | $110.5K | 0.00% | +28,254 | New |
| Prescott Group Capital Management, L.L.C. | 30,000 | $117.0K | 0.03% | +30,000 | New |
| Letko, Brosseau & Associates Inc | 31,900 | $124.7K | 0.00% | 00.0% | Unchanged |
| BlackRock Inc. | 47,482 | $185.7K | 0.00% | −1,132−2.3% | Reduced |
| Renaissance Technologies LLC | 49,800 | $195.0K | 0.00% | −21,200−29.9% | Reduced |
| Northern Trust Corp | 57,009 | $222.9K | 0.00% | +27,296+91.9% | Added |
| Citigroup Inc | 67,677 | $264.6K | 0.00% | +67,677 | New |
| State Street Corp | 95,080 | $371.8K | 0.00% | +39,300+70.5% | Added |
| Clearline Capital LP | 119,128 | $465.8K | 0.05% | 00.0% | Unchanged |
| Bank of America Corp | 125,954 | $492.5K | 0.00% | +13,140+11.6% | Added |
| Alyeska Investment Group, L.P. | 130,839 | $511.6K | 0.00% | −350,607−72.8% | Reduced |
| Bridgeway Capital Management, LLC | 141,800 | $554.4K | 0.01% | +45,000+46.5% | Added |
| Susquehanna International Group, LLP | 162,860 | $636.8K | 0.00% | +150,975+1,270.3% | Added |
| Boothbay Fund Management, LLC | 234,003 | $915.0K | 0.03% | +70,328+43.0% | Added |
| Millennium Management LLC | 263,349 | $1.03M | 0.00% | +263,349 | New |
| Ensign Peak Advisors, Inc | 301,533 | $1.18M | 0.00% | −702−0.2% | Reduced |
| Geode Capital Management, LLC | 308,690 | $1.21M | 0.00% | +159,850+107.4% | Added |
| Soleus Capital Management, L.P. | 592,417 | $2.32M | 0.23% | 00.0% | Unchanged |
| Parkman Healthcare Partners LLC | 625,056 | $2.44M | 0.45% | +25,056+4.2% | Added |
| Vanguard Group Inc | 864,332 | $3.38M | 0.00% | +73,396+9.3% | Added |
| VR Adviser, LLC | 924,170 | $3.61M | 0.38% | 00.0% | Unchanged |
| Ikarian Capital, LLC | 1,254,384 | $4.90M | 1.82% | +275,758+28.2% | Added |
| Pura Vida Investments, LLC | 1,413,242 | $5.53M | 2.71% | 00.0% | Unchanged |
| Armistice Capital, LLC | 1,550,000 | $6.06M | 0.18% | −2,462,036−61.4% | Reduced |
| Samsara BioCapital, LLC | 2,780,261 | $10.9M | 3.33% | 00.0% | Unchanged |
| Citadel Advisors LLC | 2,848,564 | $11.1M | 0.01% | −6140.0% | Reduced |
| Nantahala Capital Management, LLC | 4,050,218 | $15.8M | 2.01% | +92,676+2.3% | Added |
| Perceptive Advisors LLC | 12,757,562 | $49.9M | 1.68% | 00.0% | Unchanged |
| DAFNA Capital Management LLC | 0 | $0 | 0.00% | −361,084−100.0% | Sold out |
| Worth Asset Management, LLC | 0 | $0 | 0.00% | −650−100.0% | Sold out |
| Morgan Stanley | 0 | $0 | 0.00% | −510−100.0% | Sold out |
| FMR LLC | 0 | $0 | 0.00% | −11−100.0% | Sold out |