Lyra Therapeutics, Inc.
LYRADelisted Apr 20, 2026- Industry
- Surgical & Medical Instruments & Apparatus
- SEC CIK
- 0001327273
Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.
13F holders, Q3 2024
Institutional positions in Lyra Therapeutics, Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 62
- +12 vs. Q2 2024
- Shares held
- 32.5M
- +2.61M (+8.7%) vs. Q2 2024
- Total value
- $8.36M
- +$85.3K (+1.0%) vs. Q2 2024
- New holders
- 20
- 12 more added
- Sold out
- 8
- 14 more reduced
1 institution that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 1 | $51.1K |
| Q4 2025 | 23 | $747.3K |
| Q3 2025 | 26 | $2.93M |
| Q2 2025 | 30 | $4.42M |
| Q1 2025 | 57 | $3.23M |
| Q4 2024 | 54 | $5.54M |
| Q3 2024 | 62 | $8.36M |
| Q2 2024 | 51 | $9.06M |
| Q1 2024 | 79 | $283.4M |
| Q4 2023 | 60 | $222.0M |
| Q3 2023 | 45 | $124.8M |
| Q2 2023 | 39 | $138.4M |
| Q1 2023 | 31 | $38.1M |
| Q4 2022 | 37 | $59.9M |
| Q3 2022 | 38 | $96.0M |
| Q2 2022 | 38 | $108.9M |
| Q1 2022 | 28 | $20.2M |
| Q4 2021 | 34 | $22.4M |
| Q3 2021 | 37 | $60.8M |
| Q2 2021 | 46 | $56.0M |
| Q1 2021 | 50 | $87.6M |
Institutions, Q3 2024
Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc.; share changes are against Q2 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Perceptive Advisors LLC | 12,757,562 | $3.28M | 0.07% | 00.0% | Unchanged |
| Citadel Advisors LLC | 4,772,816 | $1.23M | 0.00% | 00.0% | Unchanged |
| BlackRock, Inc. | 2,993,626 | $769.4K | 0.00% | +2,993,626 | New |
| Samsara BioCapital, LLC | 2,780,261 | $714.5K | 0.14% | 00.0% | Unchanged |
| Vanguard Group Inc | 1,779,263 | $457.3K | 0.00% | +48,348+2.8% | Added |
| Ikarian Capital, LLC | 1,056,829 | $271.6K | 0.08% | 00.0% | Unchanged |
| SEI Investments Co | 997,782 | $256.4K | 0.00% | +997,782 | New |
| Geode Capital Management, LLC | 768,388 | $197.5K | 0.00% | +13,293+1.8% | Added |
| Morgan Stanley | 652,381 | $167.7K | 0.00% | −159,364−19.6% | Reduced |
| Goldman Sachs Group Inc | 547,339 | $140.7K | 0.00% | +522,948+2,144.0% | Added |
| State Street Corp | 488,720 | $125.6K | 0.00% | +228,900+88.1% | Added |
| Two Sigma Advisers, LP | 460,300 | $118.3K | 0.00% | −221,300−32.5% | Reduced |
| Two Sigma Investments, LP | 282,547 | $72.6K | 0.00% | −208,314−42.4% | Reduced |
| Everhart Financial Group, Inc. | 252,708 | $64.9K | 0.01% | +252,708 | New |
| Boothbay Fund Management, LLC | 232,670 | $59.8K | 0.00% | 00.0% | Unchanged |
| Northern Trust Corp | 183,284 | $47.1K | 0.00% | +99,424+118.6% | Added |
| ExodusPoint Capital Management, LP | 159,238 | $41.0K | 0.00% | +159,238 | New |
| New York State Common Retirement Fund | 154,800 | $39.8K | 0.00% | −228,100−59.6% | Reduced |
| Bank of Montreal | 119,379 | $31.7K | 0.00% | +119,379 | New |
| Charles Schwab Investment Management Inc | 111,609 | $28.7K | 0.00% | 00.0% | Unchanged |
| Acadian Asset Management LLC | 110,493 | $28.0K | 0.00% | −875,138−88.8% | Reduced |
| Beacon Pointe Advisors, LLC | 77,112 | $19.8K | 0.00% | +77,112 | New |
| Bank of New York Mellon Corp | 75,966 | $19.5K | 0.00% | −1,457−1.9% | Reduced |
| Barclays PLC | 63,303 | $16.3K | 0.00% | +46,699+281.3% | Added |
| JPMorgan Chase & Co | 59,761 | $15.4K | 0.00% | +39,102+189.3% | Added |
| Jane Street Group, LLC | 54,601 | $14.0K | 0.00% | +11,925+27.9% | Added |
| AQR Capital Management LLC | 54,030 | $13.9K | 0.00% | +54,030 | New |
| Bank of America Corp | 49,228 | $12.7K | 0.00% | −37,231−43.1% | Reduced |
| Rhumbline Advisers | 41,258 | $10.6K | 0.00% | −2,127−4.9% | Reduced |
| FMR LLC | 40,262 | $10.3K | 0.00% | +40,262 | New |
| Citigroup Inc | 35,036 | $9.00K | 0.00% | +24,384+228.9% | Added |
| SG Americas Securities, LLC | 36,409 | $9.00K | 0.00% | +36,409 | New |
| Alliancebernstein L.P. | 33,120 | $8.51K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global ETFs Holdings Ltd. | 26,554 | $6.82K | 0.00% | +26,554 | New |
| Corebridge Financial, Inc. | 25,877 | $6.65K | 0.00% | −159−0.6% | Reduced |
| UBS Group AG | 24,915 | $6.40K | 0.00% | +10,218+69.5% | Added |
| Invesco Ltd. | 22,654 | $5.82K | 0.00% | −170−0.7% | Reduced |
| Price T Rowe Associates Inc | 17,541 | $5.00K | 0.00% | 00.0% | Unchanged |
| XTX Topco Ltd | 17,776 | $4.57K | 0.00% | −16,175−47.6% | Reduced |
| Wells Fargo & Company | 17,596 | $4.52K | 0.00% | −22−0.1% | Reduced |
| Tower Research Capital LLC (TRC) | 15,123 | $3.89K | 0.00% | +8,301+121.7% | Added |
| Susquehanna International Group, LLP | 12,913 | $3.32K | 0.00% | −22,247−63.3% | Reduced |
| DLK Investment Management, LLC | 12,000 | $3.08K | 0.00% | 00.0% | Unchanged |
| Diversified, LLC | 11,932 | $3.07K | 0.00% | +11,932 | New |
| Diversified Enterprises, LLC | 11,932 | $3.07K | 0.00% | +11,932 | New |
| Ameritas Investment Partners, Inc. | 4,741 | $1.22K | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 4,157 | $1.00K | 0.00% | −124,984−96.8% | Reduced |
| Royal Bank of Canada | 6,171 | $1.00K | 0.00% | +1,298+26.6% | Added |
| National Bank of Canada | 3,700 | $951 | 0.00% | 00.0% | Unchanged |
| Geneos Wealth Management Inc. | 3,538 | $920 | 0.00% | +3,538 | New |
| California State Teachers Retirement System | 3,507 | $901 | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 1,378 | $357 | 0.00% | 00.0% | Unchanged |
| Comerica Bank | 1,159 | $298 | 0.00% | 00.0% | Unchanged |
| Bryn Mawr Trust Co | 1,025 | $263 | 0.00% | +1,025 | New |
| Capital Performance Advisors LLP | 533 | $137 | 0.00% | +533 | New |
| Jones Financial Companies LLLP | 500 | $133 | 0.00% | +500 | New |
| Sterling Capital Management LLC | 88 | $23 | 0.00% | +88 | New |
| Northwestern Mutual Wealth Management Co | 70 | $18 | 0.00% | +70 | New |
| Farther Finance Advisors, LLC | 38 | $10 | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 37 | $10 | 0.00% | +37 | New |
| Amalgamated Bank | 1,674 | $0 | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 737 | $0 | 0.00% | +737 | New |
| Rosalind Advisors, Inc. | 0 | $0 | 0.00% | −1,034,773−100.0% | Sold out |
| Clearline Capital LP | 0 | $0 | 0.00% | −119,128−100.0% | Sold out |
| Alpine Global Management, LLC | 0 | $0 | 0.00% | −46,439−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −31,690−100.0% | Sold out |
| Letko, Brosseau & Associates Inc | 0 | $0 | 0.00% | −31,900−100.0% | Sold out |
| Y-Intercept (Hong Kong) Ltd | 0 | $0 | 0.00% | −27,516−100.0% | Sold out |
| Dimensional Fund Advisors LP | 0 | $0 | 0.00% | −21,471−100.0% | Sold out |
| Millennium Management LLC | 0 | $0 | 0.00% | −20,350−100.0% | Sold out |
| BlackRock Inc. | – | – | – | – | Not filed |