Lyra Therapeutics, Inc.
LYRADelisted Apr 20, 2026- Industry
- Surgical & Medical Instruments & Apparatus
- SEC CIK
- 0001327273
Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.
13F holders, Q1 2023
Institutional positions in Lyra Therapeutics, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 31
- −5 vs. Q4 2022
- Shares held
- 18.9M
- −148.4K (−0.8%) vs. Q4 2022
- Total value
- $38.1M
- −$21.8M (−36.4%) vs. Q4 2022
- New holders
- 2
- 5 more added
- Sold out
- 7
- 4 more reduced
1 institution that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 1 | $51.1K |
| Q4 2025 | 23 | $747.3K |
| Q3 2025 | 26 | $2.93M |
| Q2 2025 | 30 | $4.42M |
| Q1 2025 | 57 | $3.23M |
| Q4 2024 | 54 | $5.54M |
| Q3 2024 | 62 | $8.36M |
| Q2 2024 | 51 | $9.06M |
| Q1 2024 | 79 | $283.4M |
| Q4 2023 | 60 | $222.0M |
| Q3 2023 | 45 | $124.8M |
| Q2 2023 | 39 | $138.4M |
| Q1 2023 | 31 | $38.1M |
| Q4 2022 | 37 | $59.9M |
| Q3 2022 | 38 | $96.0M |
| Q2 2022 | 38 | $108.9M |
| Q1 2022 | 28 | $20.2M |
| Q4 2021 | 34 | $22.4M |
| Q3 2021 | 37 | $60.8M |
| Q2 2021 | 46 | $56.0M |
| Q1 2021 | 50 | $87.6M |
Institutions, Q1 2023
Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc.; share changes are against Q4 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| JPMorgan Chase & Co | 34 | $0 | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 114 | $229 | 0.00% | +1+0.9% | Added |
| Advisor Group Holdings, Inc. | 500 | $1.00K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 500 | $1.00K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 500 | $1.00K | 0.00% | 00.0% | Unchanged |
| Worth Asset Management, LLC | 650 | $1.31K | 0.00% | 00.0% | Unchanged |
| Ameliora Wealth Management Ltd. | 750 | $1.55K | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 853 | $1.71K | 0.00% | −2,544−74.9% | Reduced |
| Citadel Advisors LLC | 7,934 | $16.4K | 0.00% | −17,343−68.6% | Reduced |
| Tower Research Capital LLC (TRC) | 9,972 | $20.0K | 0.00% | +5,186+108.4% | Added |
| Squarepoint Ops LLC | 11,280 | $23.4K | 0.00% | +11,280 | New |
| Two Sigma Advisers, LP | 28,300 | $56.9K | 0.00% | −300−1.0% | Reduced |
| Northern Trust Corp | 29,829 | $60.0K | 0.00% | 00.0% | Unchanged |
| Boothbay Fund Management, LLC | 34,721 | $69.8K | 0.00% | 00.0% | Unchanged |
| State Street Corp | 37,580 | $77.8K | 0.00% | 00.0% | Unchanged |
| BlackRock Inc. | 41,380 | $83.2K | 0.00% | +1,266+3.2% | Added |
| Renaissance Technologies LLC | 47,851 | $96.0K | 0.00% | +10,651+28.6% | Added |
| Millennium Management LLC | 58,092 | $120.0K | 0.00% | +58,092 | New |
| Bank of America Corp | 104,768 | $210.6K | 0.00% | +3,014+3.0% | Added |
| Clearline Capital LP | 119,128 | $239.4K | 0.04% | 00.0% | Unchanged |
| Bridgeway Capital Management, LLC | 146,800 | $303.9K | 0.01% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 148,840 | $308.1K | 0.00% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 302,235 | $625.6K | 0.00% | 00.0% | Unchanged |
| Ikarian Capital, LLC | 343,685 | $711.4K | 0.30% | 00.0% | Unchanged |
| Soleus Capital Management, L.P. | 592,417 | $1.19M | 0.15% | 00.0% | Unchanged |
| Vanguard Group Inc | 790,936 | $1.59M | 0.00% | 00.0% | Unchanged |
| VR Adviser, LLC | 924,170 | $1.86M | 0.36% | 00.0% | Unchanged |
| Samsara BioCapital, LLC | 1,777,251 | $3.57M | 0.74% | 00.0% | Unchanged |
| Pura Vida Investments, LLC | 1,996,972 | $4.01M | 0.41% | −160,326−7.4% | Reduced |
| Nantahala Capital Management, LLC | 2,220,830 | $4.46M | 0.43% | 00.0% | Unchanged |
| Perceptive Advisors LLC | 9,146,730 | $18.4M | 0.54% | 00.0% | Unchanged |
| Anson Funds Management LP | 0 | $0 | 0.00% | −39,127−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −13,582−100.0% | Sold out |
| Belpointe Asset Management LLC | 0 | $0 | 0.00% | −3,703−100.0% | Sold out |
| Royal Bank of Canada | 0 | $0 | 0.00% | −491−100.0% | Sold out |
| FMR LLC | 0 | $0 | 0.00% | −450−100.0% | Sold out |
| Investors Research Corp | 0 | $0 | 0.00% | −15−100.0% | Sold out |
| Morgan Stanley | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| CoreCap Advisors, LLC | – | – | – | – | Not filed |