Lyra Therapeutics, Inc.
LYRADelisted Apr 20, 2026- Industry
- Surgical & Medical Instruments & Apparatus
- SEC CIK
- 0001327273
Lyra Therapeutics, Inc. was delisted on Apr 20, 2026; its insiders filed their last Form 4 on May 15, 2026; 23 institutions reported holding it in 13F filings for Q4 2025, worth $747.3K in total; no superinvestor held it.
13F holders, Q2 2023
Institutional positions in Lyra Therapeutics, Inc. as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 39
- +8 vs. Q1 2023
- Shares held
- 33.7M
- +14.8M (+78.1%) vs. Q1 2023
- Total value
- $138.4M
- +$100.3M (+263.2%) vs. Q1 2023
- New holders
- 11
- 12 more added
- Sold out
- 3
- 5 more reduced
Compare with Q1 2023: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LYRA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 0 | $0 |
| Q1 2026 | 1 | $51.1K |
| Q4 2025 | 23 | $747.3K |
| Q3 2025 | 26 | $2.93M |
| Q2 2025 | 30 | $4.42M |
| Q1 2025 | 57 | $3.23M |
| Q4 2024 | 54 | $5.54M |
| Q3 2024 | 62 | $8.36M |
| Q2 2024 | 51 | $9.06M |
| Q1 2024 | 79 | $283.4M |
| Q4 2023 | 60 | $222.0M |
| Q3 2023 | 45 | $124.8M |
| Q2 2023 | 39 | $138.4M |
| Q1 2023 | 31 | $38.1M |
| Q4 2022 | 37 | $59.9M |
| Q3 2022 | 38 | $96.0M |
| Q2 2022 | 38 | $108.9M |
| Q1 2022 | 28 | $20.2M |
| Q4 2021 | 34 | $22.4M |
| Q3 2021 | 37 | $60.8M |
| Q2 2021 | 46 | $56.0M |
| Q1 2021 | 50 | $87.6M |
Institutions, Q2 2023
Shares, value and share of portfolio for each institution holding Lyra Therapeutics, Inc.; share changes are against Q1 2023.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Royal Bank of Canada | 74 | $0 | 0.00% | +74 | New |
| FMR LLC | 11 | $45 | 0.00% | +11 | New |
| UBS Group AG | 18 | $74 | 0.00% | −835−97.9% | Reduced |
| JPMorgan Chase & Co | 34 | $140 | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 119 | $489 | 0.00% | +5+4.4% | Added |
| Rhumbline Advisers | 296 | $1.22K | 0.00% | +296 | New |
| US Bancorp | 500 | $2.06K | 0.00% | 00.0% | Unchanged |
| Signaturefd, LLC | 500 | $2.06K | 0.00% | 00.0% | Unchanged |
| Morgan Stanley | 510 | $2.10K | 0.00% | +510 | New |
| Worth Asset Management, LLC | 650 | $2.67K | 0.00% | 00.0% | Unchanged |
| Ameliora Wealth Management Ltd. | 750 | $3.08K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 1,294 | $4.80K | 0.00% | +794+158.8% | Added |
| Tower Research Capital LLC (TRC) | 1,442 | $5.93K | 0.00% | −8,530−85.5% | Reduced |
| Simplex Trading, LLC | 1,795 | $7.00K | 0.00% | +1,795 | New |
| Susquehanna International Group, LLP | 11,885 | $48.8K | 0.00% | +11,885 | New |
| Northern Trust Corp | 29,713 | $122.1K | 0.00% | −116−0.4% | Reduced |
| Letko, Brosseau & Associates Inc | 31,900 | $131.1K | 0.00% | +31,900 | New |
| BlackRock Inc. | 48,614 | $199.8K | 0.00% | +7,234+17.5% | Added |
| State Street Corp | 55,780 | $229.3K | 0.00% | +18,200+48.4% | Added |
| Renaissance Technologies LLC | 71,000 | $292.0K | 0.00% | +23,149+48.4% | Added |
| Bridgeway Capital Management, LLC | 96,800 | $397.8K | 0.01% | −50,000−34.1% | Reduced |
| Bank of America Corp | 112,814 | $463.7K | 0.00% | +8,046+7.7% | Added |
| Clearline Capital LP | 119,128 | $489.6K | 0.06% | 00.0% | Unchanged |
| Geode Capital Management, LLC | 148,840 | $611.7K | 0.00% | 00.0% | Unchanged |
| Boothbay Fund Management, LLC | 163,675 | $672.7K | 0.02% | +128,954+371.4% | Added |
| Ensign Peak Advisors, Inc | 302,235 | $1.24M | 0.00% | 00.0% | Unchanged |
| DAFNA Capital Management LLC | 361,084 | $1.48M | 0.41% | +361,084 | New |
| Alyeska Investment Group, L.P. | 481,446 | $1.96M | 0.01% | +481,446 | New |
| Soleus Capital Management, L.P. | 592,417 | $2.43M | 0.27% | 00.0% | Unchanged |
| Parkman Healthcare Partners LLC | 600,000 | $2.47M | 0.43% | +600,000 | New |
| Vanguard Group Inc | 790,936 | $3.25M | 0.00% | 00.0% | Unchanged |
| VR Adviser, LLC | 924,170 | $3.80M | 0.61% | 00.0% | Unchanged |
| Ikarian Capital, LLC | 978,626 | $4.02M | 1.42% | +634,941+184.7% | Added |
| Pura Vida Investments, LLC | 1,413,242 | $5.72M | 2.37% | −583,730−29.2% | Reduced |
| Samsara BioCapital, LLC | 2,780,261 | $11.4M | 2.01% | +1,003,010+56.4% | Added |
| Citadel Advisors LLC | 2,849,178 | $11.7M | 0.01% | +2,841,244+35,811.0% | Added |
| Nantahala Capital Management, LLC | 3,957,542 | $16.3M | 1.97% | +1,736,712+78.2% | Added |
| Armistice Capital, LLC | 4,012,036 | $16.5M | 0.41% | +4,012,036 | New |
| Perceptive Advisors LLC | 12,757,562 | $52.4M | 1.52% | +3,610,832+39.5% | Added |
| Millennium Management LLC | 0 | $0 | 0.00% | −58,092−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −28,300−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −11,280−100.0% | Sold out |