Lexicon Pharmaceuticals, Inc.
LXRX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001062822
No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.
13F holders, Q1 2025
Institutional positions in Lexicon Pharmaceuticals, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 127
- +2 vs. Q4 2024
- Shares held
- 265.8M
- −30.8M (−10.4%) vs. Q4 2024
- Total value
- $122.5M
- −$96.9M (−44.2%) vs. Q4 2024
- New holders
- 31
- 34 more added
- Sold out
- 29
- 32 more reduced
2 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 149 | $875.1M |
| Q1 2026 | 137 | $504.5M |
| Q4 2025 | 126 | $299.5M |
| Q3 2025 | 124 | $344.4M |
| Q2 2025 | 123 | $242.9M |
| Q1 2025 | 127 | $122.5M |
| Q4 2024 | 127 | $220.1M |
| Q3 2024 | 137 | $453.1M |
| Q2 2024 | 127 | $471.0M |
| Q1 2024 | 118 | $417.8M |
| Q4 2023 | 106 | $279.8M |
| Q3 2023 | 112 | $205.8M |
| Q2 2023 | 123 | $438.2M |
| Q1 2023 | 104 | $353.8M |
| Q4 2022 | 105 | $280.5M |
| Q3 2022 | 98 | $357.3M |
| Q2 2022 | 86 | $221.0M |
| Q1 2022 | 101 | $251.3M |
| Q4 2021 | 110 | $478.9M |
| Q3 2021 | 96 | $583.0M |
| Q2 2021 | 107 | $540.2M |
| Q1 2021 | 107 | $711.5M |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Artal Group S.A. | 136,180,481 | $62.6M | 7.08% | 00.0% | Unchanged |
| Siren, L.L.C. | 38,918,903 | $17.9M | 1.01% | 00.0% | Unchanged |
| FMR LLC | 34,543,197 | $15.9M | 0.00% | −17,427,258−33.5% | Reduced |
| BlackRock, Inc. | 10,013,007 | $4.61M | 0.00% | −320,151−3.1% | Reduced |
| Vanguard Group Inc | 9,557,175 | $4.41M | 0.00% | −324,553−3.3% | Reduced |
| Schonfeld Strategic Advisors LLC | 8,212,993 | $3.78M | 0.03% | +654,372+8.7% | Added |
| Geode Capital Management, LLC | 3,689,271 | $1.70M | 0.00% | +168,016+4.8% | Added |
| State Street Corp | 2,607,574 | $1.20M | 0.00% | −110,674−4.1% | Reduced |
| CIBC Private Wealth Group, LLC | 2,240,000 | $1.12M | 0.00% | +2,240,000 | New |
| UBS Group AG | 2,095,340 | $966.0K | 0.00% | +1,409,223+205.4% | Added |
| Ikarian Capital, LLC | 1,417,952 | $653.4K | 0.21% | −132,048−8.5% | Reduced |
| AQR Capital Management LLC | 1,173,225 | $540.6K | 0.00% | +1,173,225 | New |
| Charles Schwab Investment Management Inc | 1,150,771 | $530.3K | 0.00% | −40,320−3.4% | Reduced |
| Tang Capital Management LLC | 1,150,268 | $530.0K | 0.03% | +300,000+35.3% | Added |
| Northern Trust Corp | 1,109,887 | $511.4K | 0.00% | −198,764−15.2% | Reduced |
| Susquehanna International Group, LLP | 951,135 | $438.3K | 0.00% | +400,244+72.7% | Added |
| Hennion & Walsh Asset Management, Inc. | 830,054 | $382.5K | 0.02% | −33,201−3.8% | Reduced |
| Gsa Capital Partners LLP | 807,492 | $372.0K | 0.03% | +807,492 | New |
| Monaco Asset Management SAM | 734,148 | $338.3K | 0.17% | +734,148 | New |
| Morgan Stanley | 641,629 | $295.7K | 0.00% | +115,479+21.9% | Added |
| Acadian Asset Management LLC | 573,688 | $263.0K | 0.00% | +573,688 | New |
| BBR Partners, LLC | 570,000 | $262.7K | 0.02% | +100,000+21.3% | Added |
| Nantahala Capital Management, LLC | 460,850 | $212.4K | 0.02% | −6,143,300−93.0% | Reduced |
| Boothbay Fund Management, LLC | 454,891 | $209.6K | 0.01% | −25,931−5.4% | Reduced |
| Virtus Investment Advisers, Inc. | 436,672 | $201.2K | 0.05% | +436,672 | New |
| Group One Trading, L.P. | 365,806 | $168.6K | 0.01% | +51,402+16.3% | Added |
| Goldman Sachs Group Inc | 355,152 | $163.7K | 0.00% | −185,055−34.3% | Reduced |
| Bank of New York Mellon Corp | 310,119 | $142.9K | 0.00% | −4,800−1.5% | Reduced |
| Invesco Ltd. | 285,759 | $131.7K | 0.00% | +181,265+173.5% | Added |
| Alliancebernstein L.P. | 246,121 | $113.4K | 0.00% | 00.0% | Unchanged |
| Squarepoint Ops LLC | 195,409 | $90.0K | 0.00% | +195,409 | New |
| Ieq Capital, LLC | 177,302 | $81.7K | 0.00% | +177,302 | New |
| Simplex Trading, LLC | 174,982 | $80.0K | 0.00% | +78,899+82.1% | Added |
| Point72 Asia (Singapore) Pte. Ltd. | 171,147 | $78.9K | 0.02% | +171,147 | New |
| Cerity Partners LLC | 170,387 | $78.5K | 0.00% | +73,875+76.5% | Added |
| Barclays PLC | 146,071 | $67.3K | 0.00% | −97,245−40.0% | Reduced |
| Rhumbline Advisers | 137,230 | $63.3K | 0.00% | −15,921−10.4% | Reduced |
| Compagnie Lombard Odier SCmA | 110,000 | $50.7K | 0.00% | 00.0% | Unchanged |
| CWM, LLC | 105,504 | $49.0K | 0.00% | +104,373+9,228.4% | Added |
| Bank of Montreal | 100,000 | $46.1K | 0.00% | +30,000+42.9% | Added |
| Citigroup Inc | 96,968 | $44.7K | 0.00% | −9,818−9.2% | Reduced |
| Bank of America Corp | 96,387 | $44.3K | 0.00% | −40,020−29.3% | Reduced |
| Deutsche Bank AG | 94,394 | $43.4K | 0.00% | −221,265−70.1% | Reduced |
| Price T Rowe Associates Inc | 92,248 | $43.0K | 0.00% | +14,746+19.0% | Added |
| Commonwealth Equity Services, LLC | 90,864 | $42.0K | 0.00% | −10,284−10.2% | Reduced |
| BNP Paribas Arbitrage, SA | 89,114 | $41.1K | 0.00% | +69,410+352.3% | Added |
| JPMorgan Chase & Co | 88,199 | $40.6K | 0.00% | +582+0.7% | Added |
| Intech Investment Management LLC | 73,853 | $34.0K | 0.00% | +17,164+30.3% | Added |
| China Universal Asset Management Co., Ltd. | 72,509 | $33.4K | 0.00% | −4,141−5.4% | Reduced |
| LPL Financial LLC | 70,957 | $32.7K | 0.00% | +13,950+24.5% | Added |
| Wealth Enhancement Advisory Services, LLC | 69,207 | $31.9K | 0.00% | +69,207 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 68,683 | $31.6K | 0.00% | +2,901+4.4% | Added |
| SG Americas Securities, LLC | 68,012 | $31.0K | 0.00% | +12,704+23.0% | Added |
| KWB Wealth | 40,640 | $30.0K | 0.00% | 00.0% | Unchanged |
| Wells Fargo & Company | 63,928 | $29.5K | 0.00% | +1,405+2.2% | Added |
| Straight Path Wealth Management | 62,666 | $28.9K | 0.01% | +62,666 | New |
| Corebridge Financial, Inc. | 56,248 | $25.9K | 0.00% | −834−1.5% | Reduced |
| Pinnacle Associates Ltd | 54,180 | $25.0K | 0.00% | −1,371,112−96.2% | Reduced |
| Wedbush Securities Inc | 40,850 | $19.0K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 41,162 | $19.0K | 0.00% | −8,298−16.8% | Reduced |
| Fortis Group Advisors, LLC | 37,800 | $17.4K | 0.00% | +37,800 | New |
| JustInvest LLC | 36,736 | $16.9K | 0.00% | +13,513+58.2% | Added |
| Pallas Capital Advisors LLC | 36,208 | $16.7K | 0.00% | +36,208 | New |
| University of Texas/Texas Am Investment Managment Co | 35,714 | $16.5K | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 33,702 | $15.5K | 0.00% | 00.0% | Unchanged |
| Captrust Financial Advisors | 33,184 | $15.3K | 0.00% | +19,826+148.4% | Added |
| Pathstone Holdings, LLC | 31,397 | $14.5K | 0.00% | −22,654−41.9% | Reduced |
| Police & Firemen's Retirement System of New Jersey | 29,715 | $13.7K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 28,107 | $13.0K | 0.00% | +15,952+131.2% | Added |
| CIBC World Markets Corp | 25,477 | $11.7K | 0.00% | +14,733+137.1% | Added |
| SIH Partners, LLLP | 23,712 | $10.9K | 0.00% | +23,712 | New |
| Cambridge Investment Research Advisors, Inc. | 22,075 | $10.0K | 0.00% | −1,538−6.5% | Reduced |
| Victory Capital Management Inc | 21,633 | $9.97K | 0.00% | +774+3.7% | Added |
| Steward Partners Investment Advisory, LLC | 21,323 | $9.83K | 0.00% | +20,923+5,230.8% | Added |
| Simplicity Wealth,LLC | 20,447 | $9.42K | 0.00% | +20,447 | New |
| Oppenheimer & Co Inc | 20,100 | $9.26K | 0.00% | +20,100 | New |
| Tiaa Trust, National Association | 20,000 | $9.22K | 0.00% | 00.0% | Unchanged |
| Invera Wealth Advisors, LLC | 20,000 | $9.22K | 0.01% | +20,000 | New |
| Ethic Inc. | 17,259 | $8.01K | 0.00% | +17,259 | New |
| HSBC Holdings PLC | 13,415 | $7.76K | 0.00% | −87−0.6% | Reduced |
| Merit Financial Group, LLC | 15,492 | $7.14K | 0.00% | +15,492 | New |
| Mirae Asset Global Investments Co., Ltd. | 12,096 | $6.90K | 0.00% | +50+0.4% | Added |
| Truist Financial Corp | 14,000 | $6.45K | 0.00% | 00.0% | Unchanged |
| Voya Investment Management LLC | 13,922 | $6.42K | 0.00% | −24,496−63.8% | Reduced |
| Cubist Systematic Strategies, LLC | 13,797 | $6.36K | 0.00% | +13,797 | New |
| Point72 (DIFC) Ltd | 13,327 | $6.14K | 0.00% | +13,327 | New |
| XTX Topco Ltd | 12,471 | $5.75K | 0.00% | +12,471 | New |
| Buckingham Strategic Partners | 12,096 | $5.61K | 0.00% | +12,096 | New |
| Chemistry Wealth Management LLC | 12,000 | $5.53K | 0.00% | 00.0% | Unchanged |
| Raymond James Financial Inc | 11,912 | $5.49K | 0.00% | 00.0% | Unchanged |
| Avantax Advisory Services, Inc. | 11,724 | $5.40K | 0.00% | +11,724 | New |
| North Star Asset Management Inc | 11,500 | $5.30K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 11,466 | $5.28K | 0.00% | −99,937−89.7% | Reduced |
| Chaney Capital Management, Inc. | 11,167 | $5.15K | 0.00% | +11,167 | New |
| Berger Financial Group, Inc | 10,929 | $5.04K | 0.00% | 00.0% | Unchanged |
| Unique Wealth Strategies, LLC | 10,000 | $4.61K | 0.00% | 00.0% | Unchanged |
| Ameritas Investment Partners, Inc. | 8,867 | $4.09K | 0.00% | 00.0% | Unchanged |
| California State Teachers Retirement System | 8,319 | $3.83K | 0.00% | −186,896−95.7% | Reduced |
| Golden State Wealth Management, LLC | 3,700 | $1.71K | 0.00% | +3,700 | New |
| SBI Securities Co., Ltd. | 3,320 | $1.53K | 0.00% | +256+8.4% | Added |