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Lexicon Pharmaceuticals, Inc.

LXRX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001062822

No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.

13F holders, Q2 2023

Institutional positions in Lexicon Pharmaceuticals, Inc. as of Jun 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
123
+19 vs. Q1 2023
Shares held
191.3M
+45.7M (+31.4%) vs. Q1 2023
Total value
$438.2M
+$84.3M (+23.8%) vs. Q1 2023
New holders
26
54 more added
Sold out
7
21 more reduced

Compare with Q1 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2023: 123 institutions
Q1 2021: 107 institutionsQ2 2021: 107 institutionsQ3 2021: 96 institutionsQ4 2021: 110 institutionsQ1 2022: 101 institutionsQ2 2022: 86 institutionsQ3 2022: 98 institutionsQ4 2022: 105 institutionsQ1 2023: 104 institutionsQ2 2023: 123 institutionsQ3 2023: 112 institutionsQ4 2023: 106 institutionsQ1 2024: 118 institutionsQ2 2024: 127 institutionsQ3 2024: 137 institutionsQ4 2024: 127 institutionsQ1 2025: 127 institutionsQ2 2025: 123 institutionsQ3 2025: 124 institutionsQ4 2025: 126 institutionsQ1 2026: 137 institutionsQ2 2026: 149 institutions
Value heldQ2 2023: $438.2M
Q1 2021: $711.5MQ2 2021: $540.2MQ3 2021: $583.0MQ4 2021: $478.9MQ1 2022: $251.3MQ2 2022: $221.0MQ3 2022: $357.3MQ4 2022: $280.5MQ1 2023: $353.8MQ2 2023: $438.2MQ3 2023: $205.8MQ4 2023: $279.8MQ1 2024: $417.8MQ2 2024: $471.0MQ3 2024: $453.1MQ4 2024: $220.1MQ1 2025: $122.5MQ2 2025: $242.9MQ3 2025: $344.4MQ4 2025: $299.5MQ1 2026: $504.5MQ2 2026: $875.1M
Institutions holding LXRX and their total value by quarter
QuarterHoldersValue
Q2 2026149$875.1M
Q1 2026137$504.5M
Q4 2025126$299.5M
Q3 2025124$344.4M
Q2 2025123$242.9M
Q1 2025127$122.5M
Q4 2024127$220.1M
Q3 2024137$453.1M
Q2 2024127$471.0M
Q1 2024118$417.8M
Q4 2023106$279.8M
Q3 2023112$205.8M
Q2 2023123$438.2M
Q1 2023104$353.8M
Q4 2022105$280.5M
Q3 202298$357.3M
Q2 202286$221.0M
Q1 2022101$251.3M
Q4 2021110$478.9M
Q3 202196$583.0M
Q2 2021107$540.2M
Q1 2021107$711.5M

Institutions, Q2 2023

Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q1 2023.

Institutions holding LXRX in Q2 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Artal Group S.A.117,553,284$269.2M8.62%+27,775,050+30.9%Added
BVF Inc19,995,332$45.8M1.28%+3,846,153+23.8%Added
FMR LLC8,511,068$19.5M0.00%+3,270,821+62.4%Added
Vanguard Group Inc6,456,952$14.8M0.00%+1,157,572+21.8%Added
BlackRock Inc.6,379,186$14.6M0.00%+722,259+12.8%Added
JPMorgan Chase & Co2,931,169$6.71M0.00%−374,822−11.3%Reduced
Millennium Management LLC2,634,173$6.03M0.01%+2,610,329+10,947.5%Added
NEA Management Company, LLC2,382,286$5.46M0.42%00.0%Unchanged
Pinnacle Associates Ltd1,993,627$4.57M0.08%+53,403+2.8%Added
Octagon Capital Advisors LP1,923,076$4.40M0.61%+1,923,076New
Geode Capital Management, LLC1,840,437$4.21M0.00%+115,028+6.7%Added
Alyeska Investment Group, L.P.1,742,352$3.99M0.03%+1,742,352New
State Street Corp1,730,112$3.96M0.00%+166,014+10.6%Added
Parkman Healthcare Partners LLC1,330,616$3.05M0.53%+655,288+97.0%Added
D. E. Shaw & Co., Inc.1,213,726$2.78M0.00%−1,727,271−58.7%Reduced
Northern Trust Corp1,081,831$2.48M0.00%+318,567+41.7%Added
Ameriprise Financial Inc838,408$1.92M0.00%+838,408New
Dimensional Fund Advisors LP743,737$1.70M0.00%+24,555+3.4%Added
Charles Schwab Investment Management Inc712,375$1.63M0.00%+23,764+3.5%Added
Goldman Sachs Group Inc553,008$1.27M0.00%+264,070+91.4%Added
Fisher Asset Management, LLC523,394$1.20M0.00%−126,332−19.4%Reduced
ClariVest Asset Management LLC511,374$1.17M0.06%+121,213+31.1%Added
Ghisallo Capital Management LLC500,000$1.15M0.14%+500,000New
Schonfeld Strategic Advisors LLC493,142$1.13M0.01%+334,142+210.2%Added
Citadel Advisors LLC412,319$944.2K0.00%+301,490+272.0%Added
AXA S.A.356,400$816.2K0.00%00.0%Unchanged
Bank of New York Mellon Corp337,675$773.3K0.00%+20,173+6.4%Added
Susquehanna International Group, LLP335,457$768.2K0.00%+282,164+529.5%Added
Connor, Clark & Lunn Investment Management Ltd.334,251$765.4K0.00%+125,918+60.4%Added
Nuveen Asset Management, LLC319,194$731.0K0.00%+117,680+58.4%Added
Morgan Stanley274,543$628.7K0.00%+76,239+38.4%Added
Swiss National Bank232,000$531.3K0.00%+69,100+42.4%Added
Alliancebernstein L.P.227,111$520.1K0.00%+133,700+143.1%Added
HRT Financial LP198,676$454.0K0.00%+198,676New
Cubist Systematic Strategies, LLC179,327$410.7K0.00%+173,405+2,928.1%Added
Credit Suisse AG151,440$346.8K0.00%+88,055+138.9%Added
UBS Asset Management Americas Inc137,735$334.7K0.00%00.0%Unchanged
Wellington Management Group LLP142,006$325.2K0.00%−9,487−6.3%Reduced
Rhumbline Advisers139,747$320.0K0.00%+14,681+11.7%Added
Virtus ETF Advisers LLC137,450$314.8K0.19%+137,450New
Stifel Financial Corp128,919$295.2K0.00%+608+0.5%Added
Two Sigma Investments, LP127,642$292.3K0.00%+127,642New
Marshall Wace, LLP125,287$286.9K0.00%+125,287New
California State Teachers Retirement System124,566$285.3K0.00%+27,287+28.1%Added
Price T Rowe Associates Inc108,386$249.0K0.00%−48,235−30.8%Reduced
Legal & General Group Plc103,581$237.6K0.00%+73,525+244.6%Added
UBS Group AG97,563$223.4K0.00%−41,163−29.7%Reduced
Compagnie Lombard Odier SCmA94,000$215.3K0.01%00.0%Unchanged
Group One Trading, L.P.93,363$213.8K0.01%+59,850+178.6%Added
Natixis Advisors, L.P.87,425$200.0K0.00%−80−0.1%Reduced
Bank of America Corp78,292$179.3K0.00%+17,531+28.9%Added
Verition Fund Management LLC73,300$167.9K0.00%+73,300New
Qube Research & Technologies Ltd73,243$167.7K0.00%+12,520+20.6%Added
State of Wisconsin Investment Board61,524$140.9K0.00%−2,241−3.5%Reduced
Russell Investments Group, Ltd.55,327$126.7K0.00%00.0%Unchanged
Prudential Financial Inc51,558$118.1K0.00%−49,600−49.0%Reduced
Tudor Investment Corp Et Al48,585$111.3K0.00%+37,585+341.7%Added
Captrust Financial Advisors46,489$106.5K0.00%00.0%Unchanged
American International Group, Inc.44,591$102.1K0.00%+4,398+10.9%Added
Tower Research Capital LLC (TRC)44,578$102.1K0.00%+38,967+694.5%Added
MetLife Investment Management42,834$98.1K0.00%00.0%Unchanged
Manufacturers Life Insurance Company, The41,168$94.3K0.00%+5,225+14.5%Added
Deutsche Bank AG40,289$92.3K0.00%−12,336−23.4%Reduced
Invesco Ltd.40,117$91.9K0.00%−855−2.1%Reduced
Barclays PLC37,669$86.3K0.00%−4,627−10.9%Reduced
Voya Investment Management LLC37,359$85.6K0.00%+4,678+14.3%Added
Wells Fargo & Company36,825$84.3K0.00%+21,462+139.7%Added
University of Texas/Texas Am Investment Managment Co35,714$82.0K0.03%00.0%Unchanged
New York State Common Retirement Fund33,526$76.8K0.00%−100−0.3%Reduced
Citigroup Inc33,487$76.7K0.00%+29,442+727.9%Added
CIBC Private Wealth Group, LLC30,000$68.7K0.00%00.0%Unchanged
Beacon Pointe Advisors, LLC29,500$67.6K0.00%+14,500+96.7%Added
State Board of Administration of Florida Retirement System29,400$67.3K0.00%00.0%Unchanged
Janus Henderson Group PLC29,135$66.9K0.00%+505+1.8%Added
Teacher Retirement System of Texas28,815$66.0K0.00%+5,560+23.9%Added
Point72 Middle East FZE28,625$65.6K0.00%+28,625New
Nebula Research & Development LLC28,377$65.0K0.05%+28,377New
AQR Capital Management LLC28,057$64.3K0.00%+28,057New
Tucker Asset Management LLC27,596$63.2K0.02%+27,596New
Tiaa, FSB27,000$61.8K0.00%+27,000New
Prosperity Financial Group, Inc.26,000$59.5K0.05%+26,000New
BNP Paribas Arbitrage, SA25,140$57.6K0.00%+6,588+35.5%Added
LPL Financial LLC24,987$57.2K0.00%+4,255+20.5%Added
ProShare Advisors LLC24,315$55.7K0.00%+1,429+6.2%Added
Arizona State Retirement System23,854$54.6K0.00%+1,981+9.1%Added
Traynor Capital Management, Inc.20,806$47.6K0.01%+1,742+9.1%Added
Zurcher Kantonalbank (Zurich Cantonalbank)20,787$47.6K0.00%00.0%Unchanged
Jane Street Group, LLC20,548$47.1K0.00%−22,975−52.8%Reduced
Simplex Trading, LLC20,926$47.0K0.00%−24,698−54.1%Reduced
Victory Capital Management Inc20,251$46.4K0.00%−472−2.3%Reduced
Virtu Financial LLC19,948$46.0K0.00%−1,781−8.2%Reduced
Wolverine Trading, LLC20,689$44.9K0.00%+20,689New
Jump Financial, LLC19,280$44.2K0.00%+1,080+5.9%Added
Dark Forest Capital Management LP15,875$36.4K0.00%+15,875New
Commonwealth Equity Services, LLC15,169$35.0K0.00%+1,100+7.8%Added
Hudson Capital Management LLC15,038$34.4K0.01%00.0%Unchanged
Kestra Advisory Services, LLC14,257$32.6K0.00%+14,257New
Diametric Capital, LP13,988$32.0K0.01%+13,988New
Pinnacle Wealth Management Advisory Group, LLC12,135$27.8K0.00%+750+6.6%Added
Raymond James & Associates11,073$25.4K0.00%+11,073New