Lexicon Pharmaceuticals, Inc.
LXRX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001062822
No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.
13F holders, Q4 2024
Institutional positions in Lexicon Pharmaceuticals, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 127
- −9 vs. Q3 2024
- Shares held
- 297.7M
- +9.07M (+3.1%) vs. Q3 2024
- Total value
- $220.1M
- −$232.9M (−51.4%) vs. Q3 2024
- New holders
- 25
- 45 more added
- Sold out
- 34
- 24 more reduced
1 institution that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 149 | $875.1M |
| Q1 2026 | 137 | $504.5M |
| Q4 2025 | 126 | $299.5M |
| Q3 2025 | 124 | $344.4M |
| Q2 2025 | 123 | $242.9M |
| Q1 2025 | 127 | $122.5M |
| Q4 2024 | 127 | $220.1M |
| Q3 2024 | 137 | $453.1M |
| Q2 2024 | 127 | $471.0M |
| Q1 2024 | 118 | $417.8M |
| Q4 2023 | 106 | $279.8M |
| Q3 2023 | 112 | $205.8M |
| Q2 2023 | 123 | $438.2M |
| Q1 2023 | 104 | $353.8M |
| Q4 2022 | 105 | $280.5M |
| Q3 2022 | 98 | $357.3M |
| Q2 2022 | 86 | $221.0M |
| Q1 2022 | 101 | $251.3M |
| Q4 2021 | 110 | $478.9M |
| Q3 2021 | 96 | $583.0M |
| Q2 2021 | 107 | $540.2M |
| Q1 2021 | 107 | $711.5M |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Artal Group S.A. | 136,180,481 | $100.8M | 8.59% | 00.0% | Unchanged |
| FMR LLC | 51,970,455 | $38.4M | 0.00% | +2,103,413+4.2% | Added |
| Siren, L.L.C. | 38,918,903 | $28.8M | 1.27% | 00.0% | Unchanged |
| BlackRock, Inc. | 10,333,158 | $7.63M | 0.00% | +200,144+2.0% | Added |
| Vanguard Group Inc | 9,881,728 | $7.30M | 0.00% | +1,790,630+22.1% | Added |
| Point72 Asset Management, L.P. | 8,988,421 | $6.64M | 0.02% | +7,758,371+630.7% | Added |
| Schonfeld Strategic Advisors LLC | 7,558,621 | $5.58M | 0.04% | +5,676,021+301.5% | Added |
| Nantahala Capital Management, LLC | 6,604,150 | $4.88M | 0.34% | +4,300,000+186.6% | Added |
| Geode Capital Management, LLC | 3,521,255 | $2.60M | 0.00% | −2,716−0.1% | Reduced |
| State Street Corp | 2,718,248 | $2.01M | 0.00% | +247,033+10.0% | Added |
| NEA Management Company, LLC | 2,382,286 | $1.76M | 0.10% | 00.0% | Unchanged |
| Ikarian Capital, LLC | 1,550,000 | $1.14M | 0.33% | +1,550,000 | New |
| Pinnacle Associates Ltd | 1,425,292 | $1.05M | 0.01% | −305,529−17.7% | Reduced |
| Northern Trust Corp | 1,308,651 | $966.4K | 0.00% | +164,620+14.4% | Added |
| Charles Schwab Investment Management Inc | 1,191,091 | $879.6K | 0.00% | −226,204−16.0% | Reduced |
| Nuveen Asset Management, LLC | 1,103,840 | $815.2K | 0.00% | 00.0% | Unchanged |
| Hennion & Walsh Asset Management, Inc. | 863,255 | $637.5K | 0.03% | +132,117+18.1% | Added |
| Tang Capital Management LLC | 850,268 | $627.9K | 0.04% | +750,268+750.3% | Added |
| Wellington Management Group LLP | 747,996 | $552.4K | 0.00% | +15,249+2.1% | Added |
| UBS Group AG | 686,117 | $507.0K | 0.00% | +546,125+390.1% | Added |
| Susquehanna International Group, LLP | 550,891 | $406.8K | 0.00% | +463,390+529.6% | Added |
| Goldman Sachs Group Inc | 540,207 | $398.9K | 0.00% | +138,916+34.6% | Added |
| Morgan Stanley | 526,150 | $388.6K | 0.00% | +71,173+15.6% | Added |
| Boothbay Fund Management, LLC | 480,822 | $355.1K | 0.01% | +480,822 | New |
| BBR Partners, LLC | 470,000 | $347.1K | 0.02% | 00.0% | Unchanged |
| Swiss National Bank | 426,600 | $315.0K | 0.00% | +109,100+34.4% | Added |
| Virtus ETF Advisers LLC | 425,269 | $314.1K | 0.13% | +245,297+136.3% | Added |
| UBS Asset Management Americas Inc | 353,508 | $261.2K | 0.00% | +233,121+193.6% | Added |
| Deutsche Bank AG | 315,659 | $233.6K | 0.00% | +249,616+378.0% | Added |
| Bank of New York Mellon Corp | 314,919 | $232.6K | 0.00% | +1390.0% | Added |
| Group One Trading, L.P. | 314,404 | $232.2K | 0.01% | +314,404 | New |
| Alliancebernstein L.P. | 246,121 | $181.8K | 0.00% | −26,920−9.9% | Reduced |
| Barclays PLC | 243,316 | $179.7K | 0.00% | +49,443+25.5% | Added |
| Woodline Partners LP | 229,376 | $169.4K | 0.00% | −982,548−81.1% | Reduced |
| Jane Street Group, LLC | 220,264 | $162.7K | 0.00% | +134,903+158.0% | Added |
| California State Teachers Retirement System | 195,215 | $144.2K | 0.00% | +44,915+29.9% | Added |
| Rhumbline Advisers | 153,151 | $113.0K | 0.00% | +7,212+4.9% | Added |
| Bank of America Corp | 136,407 | $100.7K | 0.00% | +29,319+27.4% | Added |
| Stifel Financial Corp | 112,853 | $83.3K | 0.00% | +60,856+117.0% | Added |
| Legal & General Group Plc | 111,403 | $82.3K | 0.00% | 00.0% | Unchanged |
| Compagnie Lombard Odier SCmA | 110,000 | $81.2K | 0.00% | +10,000+10.0% | Added |
| Citigroup Inc | 106,786 | $78.9K | 0.00% | +17,041+19.0% | Added |
| Invesco Ltd. | 104,494 | $77.2K | 0.00% | +39,420+60.6% | Added |
| Commonwealth Equity Services, LLC | 101,148 | $75.0K | 0.00% | −7,586−7.0% | Reduced |
| Cerity Partners LLC | 96,512 | $71.3K | 0.00% | +74,000+328.7% | Added |
| Simplex Trading, LLC | 96,083 | $71.0K | 0.00% | +96,083 | New |
| Virtu Financial LLC | 88,982 | $66.0K | 0.00% | +88,982 | New |
| JPMorgan Chase & Co | 87,617 | $64.7K | 0.00% | −2,083−2.3% | Reduced |
| KWB Wealth | 40,640 | $63.8K | 0.01% | 00.0% | Unchanged |
| Price T Rowe Associates Inc | 77,502 | $57.0K | 0.00% | −39,677−33.9% | Reduced |
| China Universal Asset Management Co., Ltd. | 76,650 | $56.6K | 0.01% | +7,123+10.2% | Added |
| Bank of Montreal | 70,000 | $51.7K | 0.00% | −10.0% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 65,782 | $48.6K | 0.00% | +2,824+4.5% | Added |
| Teacher Retirement System of Texas | 65,415 | $48.0K | 0.00% | +24,615+60.3% | Added |
| Dimensional Fund Advisors LP | 64,966 | $48.0K | 0.00% | −11,120−14.6% | Reduced |
| Arizona State Retirement System | 62,976 | $46.5K | 0.00% | +16,136+34.4% | Added |
| Wells Fargo & Company | 62,523 | $46.2K | 0.00% | −13,966−18.3% | Reduced |
| Corebridge Financial, Inc. | 57,082 | $42.2K | 0.00% | −4,309−7.0% | Reduced |
| LPL Financial LLC | 57,007 | $42.1K | 0.00% | −6,028−9.6% | Reduced |
| Intech Investment Management LLC | 56,689 | $41.9K | 0.00% | −16,751−22.8% | Reduced |
| SG Americas Securities, LLC | 55,308 | $41.0K | 0.00% | +9,218+20.0% | Added |
| Pathstone Holdings, LLC | 54,051 | $39.9K | 0.00% | −4,908−8.3% | Reduced |
| Renaissance Technologies LLC | 51,141 | $37.8K | 0.00% | +51,141 | New |
| ProShare Advisors LLC | 49,460 | $36.5K | 0.00% | +6,404+14.9% | Added |
| Great West Life Assurance Co | 46,013 | $34.0K | 0.00% | 00.0% | Unchanged |
| Rpo LLC | 44,242 | $32.7K | 0.04% | +44,242 | New |
| Bayesian Capital Management, LP | 42,000 | $31.0K | 0.00% | +42,000 | New |
| Wedbush Securities Inc | 40,850 | $30.0K | 0.00% | 00.0% | Unchanged |
| Voya Investment Management LLC | 38,418 | $28.4K | 0.00% | 00.0% | Unchanged |
| University of Texas/Texas Am Investment Managment Co | 35,714 | $26.4K | 0.00% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 33,702 | $24.9K | 0.00% | 00.0% | Unchanged |
| Kestra Advisory Services, LLC | 31,500 | $23.3K | 0.00% | +16,000+103.2% | Added |
| Police & Firemen's Retirement System of New Jersey | 29,715 | $21.9K | 0.00% | +29,715 | New |
| Manufacturers Life Insurance Company, The | 29,646 | $21.9K | 0.00% | −18,402−38.3% | Reduced |
| KLP Kapitalforvaltning AS | 26,200 | $19.3K | 0.00% | +26,200 | New |
| Citadel Advisors LLC | 25,832 | $19.1K | 0.00% | −72,792−73.8% | Reduced |
| JustInvest LLC | 23,223 | $17.1K | 0.00% | +3,301+16.6% | Added |
| Cambridge Investment Research Advisors, Inc. | 23,613 | $17.0K | 0.00% | +23,613 | New |
| Victory Capital Management Inc | 20,859 | $15.4K | 0.00% | −23,448−52.9% | Reduced |
| Tiaa Trust, National Association | 20,000 | $14.8K | 0.00% | −7,057−26.1% | Reduced |
| BNP Paribas Arbitrage, SA | 19,704 | $14.6K | 0.00% | −12,149−38.1% | Reduced |
| State of Wisconsin Investment Board | 15,034 | $11.1K | 0.00% | +2,602+20.9% | Added |
| Truist Financial Corp | 14,000 | $10.3K | 0.00% | +600+4.5% | Added |
| Vermillion & White Wealth Management Group, LLC | 13,415 | $9.91K | 0.01% | 00.0% | Unchanged |
| Captrust Financial Advisors | 13,358 | $9.87K | 0.00% | +2,008+17.7% | Added |
| HSBC Holdings PLC | 13,502 | $9.65K | 0.00% | +13,502 | New |
| Mirae Asset Global Investments Co., Ltd. | 12,046 | $9.32K | 0.00% | −1,028−7.9% | Reduced |
| Pinnacle Wealth Management Advisory Group, LLC | 12,445 | $9.19K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 12,155 | $8.98K | 0.00% | +6,184+103.6% | Added |
| Chemistry Wealth Management LLC | 12,000 | $8.86K | 0.00% | 00.0% | Unchanged |
| Raymond James Financial Inc | 11,912 | $8.80K | 0.00% | +11,912 | New |
| North Star Asset Management Inc | 11,500 | $8.49K | 0.00% | −1,050−8.4% | Reduced |
| Berger Financial Group, Inc | 10,929 | $8.07K | 0.00% | 00.0% | Unchanged |
| CIBC World Markets Corp | 10,744 | $7.93K | 0.00% | +10,744 | New |
| Estabrook Capital Management | 10,000 | $7.38K | 0.00% | 00.0% | Unchanged |
| Unique Wealth Strategies, LLC | 10,000 | $7.38K | 0.00% | +10,000 | New |
| Royal Bank of Canada | 9,911 | $7.00K | 0.00% | −1,488−13.1% | Reduced |
| Ameritas Investment Partners, Inc. | 8,867 | $6.55K | 0.00% | 00.0% | Unchanged |
| Nordwand Advisors, LLC | 4,000 | $2.95K | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 3,064 | $2.26K | 0.00% | +3,064 | New |