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Lexicon Pharmaceuticals, Inc.

LXRX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001062822

No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.

13F holders, Q3 2024

Institutional positions in Lexicon Pharmaceuticals, Inc. as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
137
+12 vs. Q2 2024
Shares held
288.6M
+19.6M (+7.3%) vs. Q2 2024
Total value
$453.1M
−$1.27M (−0.3%) vs. Q2 2024
New holders
26
46 more added
Sold out
14
20 more reduced

2 institutions that held it in Q2 2024 haven't filed for Q3 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2024: 137 institutions
Q1 2021: 107 institutionsQ2 2021: 107 institutionsQ3 2021: 96 institutionsQ4 2021: 110 institutionsQ1 2022: 101 institutionsQ2 2022: 86 institutionsQ3 2022: 98 institutionsQ4 2022: 105 institutionsQ1 2023: 104 institutionsQ2 2023: 123 institutionsQ3 2023: 112 institutionsQ4 2023: 106 institutionsQ1 2024: 118 institutionsQ2 2024: 127 institutionsQ3 2024: 137 institutionsQ4 2024: 127 institutionsQ1 2025: 127 institutionsQ2 2025: 123 institutionsQ3 2025: 124 institutionsQ4 2025: 126 institutionsQ1 2026: 137 institutionsQ2 2026: 149 institutions
Value heldQ3 2024: $453.1M
Q1 2021: $711.5MQ2 2021: $540.2MQ3 2021: $583.0MQ4 2021: $478.9MQ1 2022: $251.3MQ2 2022: $221.0MQ3 2022: $357.3MQ4 2022: $280.5MQ1 2023: $353.8MQ2 2023: $438.2MQ3 2023: $205.8MQ4 2023: $279.8MQ1 2024: $417.8MQ2 2024: $471.0MQ3 2024: $453.1MQ4 2024: $220.1MQ1 2025: $122.5MQ2 2025: $242.9MQ3 2025: $344.4MQ4 2025: $299.5MQ1 2026: $504.5MQ2 2026: $875.1M
Institutions holding LXRX and their total value by quarter
QuarterHoldersValue
Q2 2026149$875.1M
Q1 2026137$504.5M
Q4 2025126$299.5M
Q3 2025124$344.4M
Q2 2025123$242.9M
Q1 2025127$122.5M
Q4 2024127$220.1M
Q3 2024137$453.1M
Q2 2024127$471.0M
Q1 2024118$417.8M
Q4 2023106$279.8M
Q3 2023112$205.8M
Q2 2023123$438.2M
Q1 2023104$353.8M
Q4 2022105$280.5M
Q3 202298$357.3M
Q2 202286$221.0M
Q1 2022101$251.3M
Q4 2021110$478.9M
Q3 202196$583.0M
Q2 2021107$540.2M
Q1 2021107$711.5M

Institutions, Q3 2024

Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q2 2024.

Institutions holding LXRX in Q3 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Artal Group S.A.136,180,481$213.8M8.98%−38,918,903−22.2%Reduced
FMR LLC49,867,042$78.3M0.00%+11,179,919+28.9%Added
Siren, L.L.C.38,918,903$61.1M3.06%+38,918,903New
OrbiMed Advisors LLC11,024,000$17.3M0.32%+5,177,900+88.6%Added
BlackRock, Inc.10,133,014$15.9M0.00%+10,133,014New
Vanguard Group Inc8,091,098$12.7M0.00%+415,973+5.4%Added
Geode Capital Management, LLC3,523,971$5.53M0.00%+273,436+8.4%Added
State Street Corp2,471,215$3.88M0.00%+157,738+6.8%Added
NEA Management Company, LLC2,382,286$3.74M0.20%00.0%Unchanged
Ameriprise Financial Inc2,327,110$3.65M0.00%+234,400+11.2%Added
Nantahala Capital Management, LLC2,304,150$3.62M0.30%00.0%Unchanged
Schonfeld Strategic Advisors LLC1,882,600$2.96M0.02%+1,311,108+229.4%Added
Pinnacle Associates Ltd1,730,821$2.65M0.05%+14,990+0.9%Added
Charles Schwab Investment Management Inc1,417,295$2.23M0.00%+58,147+4.3%Added
Millennium Management LLC1,398,876$2.20M0.00%+801,555+134.2%Added
Point72 Asset Management, L.P.1,230,050$1.93M0.01%−2,891,141−70.2%Reduced
Woodline Partners LP1,211,924$1.90M0.02%+1,211,924New
Northern Trust Corp1,144,031$1.80M0.00%+146,503+14.7%Added
Nuveen Asset Management, LLC1,103,840$1.73M0.00%+887,574+410.4%Added
Braidwell LP801,584$1.26M0.04%−7,493,366−90.3%Reduced
Wellington Management Group LLP732,747$1.15M0.00%−5,881−0.8%Reduced
Hennion & Walsh Asset Management, Inc.731,138$1.15M0.05%+188,239+34.7%Added
Marshall Wace, LLP574,150$901.4K0.00%−616,298−51.8%Reduced
Knott David M Jr500,000$785.0K0.31%+500,000New
BBR Partners, LLC470,000$737.9K0.06%+200,000+74.1%Added
Morgan Stanley454,977$714.3K0.00%+100,941+28.5%Added
Goldman Sachs Group Inc401,291$630.0K0.00%+27,860+7.5%Added
Swiss National Bank317,500$498.5K0.00%+317,500New
Bank of New York Mellon Corp314,780$494.2K0.00%−87,128−21.7%Reduced
Alliancebernstein L.P.273,041$428.7K0.00%00.0%Unchanged
Two Sigma Investments, LP204,879$321.7K0.00%+185,723+969.5%Added
Barclays PLC193,873$304.4K0.00%+154,436+391.6%Added
Squarepoint Ops LLC188,842$296.5K0.00%+188,842New
Virtus ETF Advisers LLC179,972$282.6K0.13%00.0%Unchanged
Deerfield Management Company, L.P. (Series C)156,860$246.3K0.00%+156,860New
California State Teachers Retirement System150,300$236.0K0.00%+141,981+1,706.7%Added
Rhumbline Advisers145,939$229.1K0.00%−6,846−4.5%Reduced
UBS Group AG139,992$219.8K0.00%−21,121−13.1%Reduced
UBS Asset Management Americas Inc120,387$189.0K0.00%+120,387New
Price T Rowe Associates Inc117,179$184.0K0.00%00.0%Unchanged
Legal & General Group Plc111,403$174.9K0.00%+99,937+871.6%Added
Commonwealth Equity Services, LLC108,734$171.0K0.00%+7,600+7.5%Added
Bank of America Corp107,088$168.1K0.00%+19,903+22.8%Added
Compagnie Lombard Odier SCmA100,000$157.0K0.00%+6,000+6.4%Added
Tang Capital Management LLC100,000$157.0K0.01%+100,000New
Citadel Advisors LLC98,624$154.8K0.00%−2,310,832−95.9%Reduced
Citigroup Inc89,745$140.9K0.00%+56,615+170.9%Added
JPMorgan Chase & Co89,700$140.8K0.00%−726−0.8%Reduced
Susquehanna International Group, LLP87,501$137.4K0.00%−26,625−23.3%Reduced
Jane Street Group, LLC85,361$134.0K0.00%−44,495−34.3%Reduced
XTX Topco Ltd80,423$126.3K0.01%+80,423New
Atom Investors LP77,733$122.0K0.01%+77,733New
Wells Fargo & Company76,489$120.1K0.00%+30,888+67.7%Added
Dimensional Fund Advisors LP76,086$119.5K0.00%00.0%Unchanged
Intech Investment Management LLC73,440$115.3K0.00%+73,440New
Bank of Montreal70,001$112.0K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.69,527$109.2K0.01%+27,058+63.7%Added
Deutsche Bank AG66,043$103.7K0.00%+34,153+107.1%Added
Invesco Ltd.65,074$102.2K0.00%+5,331+8.9%Added
LPL Financial LLC63,035$99.0K0.00%+1,950+3.2%Added
Mirae Asset Global ETFs Holdings Ltd.62,958$98.8K0.00%+15,775+33.4%Added
Corebridge Financial, Inc.61,391$96.4K0.00%−379−0.6%Reduced
Pathstone Holdings, LLC58,959$92.6K0.00%−1,079−1.8%Reduced
Acadian Asset Management LLC58,007$91.0K0.00%+58,007New
MetLife Investment Management55,182$86.6K0.00%00.0%Unchanged
Stifel Financial Corp51,997$81.6K0.00%+546+1.1%Added
CIBC Private Wealth Group, LLC50,010$78.5K0.00%+50,000+500,000.0%Added
Russell Investments Group, Ltd.49,100$77.1K0.00%−3,980−7.5%Reduced
Manufacturers Life Insurance Company, The48,048$75.4K0.00%−1,909−3.8%Reduced
Arizona State Retirement System46,840$73.5K0.00%+46,840New
SG Americas Securities, LLC46,090$72.0K0.00%+23,893+107.6%Added
Great West Life Assurance Co46,013$72.0K0.00%+46,013New
Victory Capital Management Inc44,307$69.6K0.00%−1,034−2.3%Reduced
KWB Wealth40,640$68.3K0.01%00.0%Unchanged
ProShare Advisors LLC43,056$67.6K0.00%+8,331+24.0%Added
Wedbush Securities Inc40,850$64.0K0.00%00.0%Unchanged
Teacher Retirement System of Texas40,800$64.0K0.00%+40,800New
Voya Investment Management LLC38,418$60.3K0.00%−1,228−3.1%Reduced
University of Texas/Texas Am Investment Managment Co35,714$56.1K0.01%00.0%Unchanged
New York State Common Retirement Fund33,702$52.9K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA31,853$50.0K0.00%+13,246+71.2%Added
Tiaa Trust, National Association27,057$42.5K0.00%00.0%Unchanged
Two Sigma Securities, LLC24,527$38.5K0.00%+6,756+38.0%Added
Cerity Partners LLC22,512$35.3K0.00%00.0%Unchanged
Cetera Investment Advisers21,775$34.2K0.00%+21,775New
Principal Securities, Inc.20,000$31.4K0.00%00.0%Unchanged
JustInvest LLC19,922$31.3K0.00%+593+3.1%Added
Kestra Advisory Services, LLC15,500$24.3K0.00%00.0%Unchanged
Cresset Asset Management, LLC15,120$23.7K0.00%00.0%Unchanged
Prosperity Financial Group, Inc.14,437$22.7K0.01%−17,063−54.2%Reduced
Vermillion & White Wealth Management Group, LLC13,415$21.1K0.02%+1,000+8.1%Added
Truist Financial Corp13,400$21.0K0.00%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.13,074$20.9K0.00%+2,282+21.1%Added
North Star Asset Management Inc12,550$19.7K0.00%00.0%Unchanged
Pinnacle Wealth Management Advisory Group, LLC12,445$19.5K0.00%00.0%Unchanged
State of Wisconsin Investment Board12,432$19.5K0.00%+12,432New
Chemistry Wealth Management LLC12,000$18.8K0.00%00.0%Unchanged
Perennial Investment Advisors, LLC11,600$18.2K0.00%+11,600New
Royal Bank of Canada11,399$18.0K0.00%+561+5.2%Added
Dynamic Technology Lab Private Ltd11,338$18.0K0.00%+11,338New