Lexicon Pharmaceuticals, Inc.
LXRX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001062822
No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.
13F holders, Q3 2022
Institutional positions in Lexicon Pharmaceuticals, Inc. as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 98
- +13 vs. Q2 2022
- Shares held
- 148.9M
- +30.1M (+25.3%) vs. Q2 2022
- Total value
- $357.3M
- +$136.3M (+61.7%) vs. Q2 2022
- New holders
- 21
- 38 more added
- Sold out
- 8
- 22 more reduced
1 institution that held it in Q2 2022 haven't filed for Q3 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 149 | $875.1M |
| Q1 2026 | 137 | $504.5M |
| Q4 2025 | 126 | $299.5M |
| Q3 2025 | 124 | $344.4M |
| Q2 2025 | 123 | $242.9M |
| Q1 2025 | 127 | $122.5M |
| Q4 2024 | 127 | $220.1M |
| Q3 2024 | 137 | $453.1M |
| Q2 2024 | 127 | $471.0M |
| Q1 2024 | 118 | $417.8M |
| Q4 2023 | 106 | $279.8M |
| Q3 2023 | 112 | $205.8M |
| Q2 2023 | 123 | $438.2M |
| Q1 2023 | 104 | $353.8M |
| Q4 2022 | 105 | $280.5M |
| Q3 2022 | 98 | $357.3M |
| Q2 2022 | 86 | $221.0M |
| Q1 2022 | 101 | $251.3M |
| Q4 2021 | 110 | $478.9M |
| Q3 2021 | 96 | $583.0M |
| Q2 2021 | 107 | $540.2M |
| Q1 2021 | 107 | $711.5M |
Institutions, Q3 2022
Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q2 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Artal Group S.A. | 89,778,234 | $215.5M | 11.25% | +18,599,870+26.1% | Added |
| BVF Inc | 16,149,179 | $38.8M | 1.60% | +2,000,000+14.1% | Added |
| BlackRock Inc. | 5,760,000 | $13.8M | 0.00% | +1,240,171+27.4% | Added |
| FMR LLC | 5,282,999 | $12.7M | 0.00% | −7,615−0.1% | Reduced |
| Vanguard Group Inc | 5,256,288 | $12.6M | 0.00% | +1,334,318+34.0% | Added |
| Point72 Asset Management, L.P. | 3,613,500 | $8.67M | 0.04% | +3,613,500 | New |
| JPMorgan Chase & Co | 3,226,433 | $7.74M | 0.00% | +2,093,656+184.8% | Added |
| D. E. Shaw & Co., Inc. | 3,043,977 | $7.31M | 0.01% | −184,095−5.7% | Reduced |
| NEA Management Company, LLC | 2,382,286 | $5.72M | 0.29% | 00.0% | Unchanged |
| Pinnacle Associates Ltd | 2,031,207 | $4.88M | 0.11% | −56,256−2.7% | Reduced |
| Geode Capital Management, LLC | 1,569,022 | $3.77M | 0.00% | +227,609+17.0% | Added |
| State Street Corp | 1,463,569 | $3.51M | 0.00% | +111,568+8.3% | Added |
| Millennium Management LLC | 905,911 | $2.17M | 0.00% | +687,963+315.7% | Added |
| Northern Trust Corp | 735,510 | $1.76M | 0.00% | +63,047+9.4% | Added |
| Charles Schwab Investment Management Inc | 662,478 | $1.59M | 0.00% | +227,914+52.4% | Added |
| Fisher Asset Management, LLC | 605,528 | $1.45M | 0.00% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 481,375 | $1.16M | 0.00% | +481,375 | New |
| Dimensional Fund Advisors LP | 463,188 | $1.11M | 0.00% | −201,600−30.3% | Reduced |
| ClariVest Asset Management LLC | 392,791 | $943.0K | 0.05% | +392,791 | New |
| Nuveen Asset Management, LLC | 306,516 | $736.0K | 0.00% | +56,582+22.6% | Added |
| Parkman Healthcare Partners LLC | 303,614 | $729.0K | 0.21% | +53,614+21.4% | Added |
| AQR Capital Management LLC | 300,219 | $721.0K | 0.00% | +300,219 | New |
| Bank of New York Mellon Corp | 291,660 | $699.0K | 0.00% | +34,564+13.4% | Added |
| Russell Investments Group, Ltd. | 248,414 | $595.0K | 0.00% | −1,903−0.8% | Reduced |
| Goldman Sachs Group Inc | 240,921 | $578.0K | 0.00% | +32,896+15.8% | Added |
| Price T Rowe Associates Inc | 193,275 | $464.0K | 0.00% | −4,166−2.1% | Reduced |
| Swiss National Bank | 172,800 | $415.0K | 0.00% | +32,000+22.7% | Added |
| Morgan Stanley | 169,083 | $405.0K | 0.00% | −399,825−70.3% | Reduced |
| Wellington Management Group LLP | 155,643 | $374.0K | 0.00% | −61,554−28.3% | Reduced |
| Stifel Financial Corp | 136,683 | $328.0K | 0.00% | −2,694−1.9% | Reduced |
| Group One Trading, L.P. | 129,272 | $310.0K | 0.01% | +34,672+36.7% | Added |
| Citadel Advisors LLC | 127,193 | $306.0K | 0.00% | −38,486−23.2% | Reduced |
| UBS Asset Management Americas Inc | 119,046 | $285.7K | 0.00% | −56,904−32.3% | Reduced |
| Rhumbline Advisers | 113,395 | $272.0K | 0.00% | +15,925+16.3% | Added |
| AXA S.A. | 112,168 | $269.2K | 0.00% | +91,268+436.7% | Added |
| Bank of America Corp | 110,133 | $264.0K | 0.00% | +71,823+187.5% | Added |
| Compagnie Lombard Odier SCmA | 98,000 | $235.0K | 0.01% | 00.0% | Unchanged |
| California State Teachers Retirement System | 96,060 | $231.0K | 0.00% | +14,835+18.3% | Added |
| UBS Group AG | 93,686 | $225.0K | 0.00% | −118,467−55.8% | Reduced |
| Natixis Advisors, L.P. | 88,411 | $212.0K | 0.00% | +88,411 | New |
| Prudential Financial Inc | 85,358 | $205.0K | 0.00% | −39,150−31.4% | Reduced |
| Alliancebernstein L.P. | 85,011 | $204.0K | 0.00% | +28,400+50.2% | Added |
| Norges Bank | 82,900 | $199.0K | 0.00% | +82,900 | New |
| Susquehanna International Group, LLP | 79,352 | $190.0K | 0.00% | −14,599−15.5% | Reduced |
| State of Wisconsin Investment Board | 75,087 | $180.0K | 0.00% | +60,519+415.4% | Added |
| Gsa Capital Partners LLP | 71,004 | $170.0K | 0.02% | −300,594−80.9% | Reduced |
| Caxton Associates LP | 54,781 | $131.0K | 0.02% | +54,781 | New |
| HRT Financial LP | 45,569 | $109.0K | 0.00% | +45,569 | New |
| Two Sigma Investments, LP | 43,297 | $104.0K | 0.00% | +43,297 | New |
| MetLife Investment Management | 40,056 | $96.1K | 0.00% | +40,056 | New |
| Credit Suisse AG | 39,483 | $95.0K | 0.00% | +508+1.3% | Added |
| American International Group, Inc. | 39,536 | $95.0K | 0.00% | +5,444+16.0% | Added |
| Great West Life Assurance Co | 37,343 | $89.0K | 0.00% | +32,708+705.7% | Added |
| Deutsche Bank AG | 36,090 | $87.0K | 0.00% | +2,998+9.1% | Added |
| University of Texas/Texas Am Investment Managment Co | 35,714 | $86.0K | 0.03% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 34,589 | $83.0K | 0.00% | −878−2.5% | Reduced |
| Jane Street Group, LLC | 34,541 | $83.0K | 0.00% | +34,541 | New |
| New York State Common Retirement Fund | 33,539 | $80.0K | 0.00% | +197+0.6% | Added |
| Voya Investment Management LLC | 32,681 | $78.4K | 0.00% | +6,330+24.0% | Added |
| Invesco Ltd. | 31,353 | $75.0K | 0.00% | +2,830+9.9% | Added |
| CIBC Private Wealth Group, LLC | 30,000 | $72.0K | 0.00% | +30,000 | New |
| State Board of Administration of Florida Retirement System | 29,400 | $71.0K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 26,653 | $64.0K | 0.00% | +7,805+41.4% | Added |
| ProShare Advisors LLC | 24,625 | $59.0K | 0.00% | +4,793+24.2% | Added |
| Commonwealth Equity Services, LLC | 24,576 | $58.0K | 0.00% | 00.0% | Unchanged |
| Teacher Retirement System of Texas | 24,096 | $58.0K | 0.00% | +24,096 | New |
| Cubist Systematic Strategies, LLC | 22,845 | $55.0K | 0.00% | +22,845 | New |
| LPL Financial LLC | 20,700 | $50.0K | 0.00% | 00.0% | Unchanged |
| Victory Capital Management Inc | 20,433 | $49.0K | 0.00% | +8,873+76.8% | Added |
| Arizona State Retirement System | 19,957 | $48.0K | 0.00% | +3,741+23.1% | Added |
| Tower Research Capital LLC (TRC) | 19,389 | $46.0K | 0.00% | +13,232+214.9% | Added |
| Manufacturers Life Insurance Company, The | 15,878 | $38.1K | 0.00% | +15,878 | New |
| BNP Paribas Arbitrage, SA | 15,459 | $37.1K | 0.00% | −644−4.0% | Reduced |
| Simplex Trading, LLC | 14,835 | $35.0K | 0.00% | +10,766+264.6% | Added |
| Virtu Financial LLC | 13,458 | $32.0K | 0.00% | +13,458 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 12,688 | $30.0K | 0.00% | 00.0% | Unchanged |
| Janus Henderson Group PLC | 11,361 | $27.0K | 0.00% | 00.0% | Unchanged |
| Berger Financial Group, Inc | 10,929 | $26.0K | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 11,037 | $26.0K | 0.00% | +1,113+11.2% | Added |
| Pegasus Asset Management, Inc. | 10,000 | $24.0K | 0.01% | 00.0% | Unchanged |
| Estabrook Capital Management | 10,000 | $24.0K | 0.00% | 00.0% | Unchanged |
| Principal Financial Group Inc | 10,006 | $24.0K | 0.00% | +10,006 | New |
| Pinnacle Wealth Management Advisory Group, LLC | 10,140 | $24.0K | 0.00% | +10,140 | New |
| Allspring Global Investments Holdings, LLC | 8,339 | $20.0K | 0.00% | −8,685−51.0% | Reduced |
| Metropolitan Life Insurance Co | 5,094 | $12.2K | 0.00% | +5,094 | New |
| Ameritas Investment Partners, Inc. | 5,367 | $12.0K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 4,637 | $11.0K | 0.00% | −11,916−72.0% | Reduced |
| Barclays PLC | 3,531 | $8.00K | 0.00% | −71,723−95.3% | Reduced |
| Advisor Group Holdings, Inc. | 3,614 | $8.00K | 0.00% | +1,023+39.5% | Added |
| China Universal Asset Management Co., Ltd. | 1,719 | $4.00K | 0.00% | +1,719 | New |
| Hall Laurie J Trustee | 1,140 | $3.00K | 0.00% | −510−30.9% | Reduced |
| Wells Fargo & Company | 761 | $2.00K | 0.00% | −566−42.7% | Reduced |
| Royal Bank of Canada | 1,035 | $2.00K | 0.00% | +115+12.5% | Added |
| Farmers & Merchants Investments Inc | 1,000 | $2.00K | 0.00% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 500 | $1.00K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 434 | $1.00K | 0.00% | 00.0% | Unchanged |
| Avion Wealth | 407 | $1.00K | 0.00% | 00.0% | Unchanged |
| Dark Forest Capital Management LP | 35 | $0 | 0.00% | +35 | New |
| Integral Health Asset Management, LLC | 0 | $0 | 0.00% | −300,000−100.0% | Sold out |
| Nomura Holdings Inc | 0 | $0 | 0.00% | −212,620−100.0% | Sold out |