Lexicon Pharmaceuticals, Inc.
LXRX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001062822
No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.
13F holders, Q1 2022
Institutional positions in Lexicon Pharmaceuticals, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 101
- −9 vs. Q4 2021
- Shares held
- 120.2M
- −1.37M (−1.1%) vs. Q4 2021
- Total value
- $251.3M
- −$227.6M (−47.5%) vs. Q4 2021
- New holders
- 7
- 33 more added
- Sold out
- 16
- 39 more reduced
Compare with Q4 2021: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 149 | $875.1M |
| Q1 2026 | 137 | $504.5M |
| Q4 2025 | 126 | $299.5M |
| Q3 2025 | 124 | $344.4M |
| Q2 2025 | 123 | $242.9M |
| Q1 2025 | 127 | $122.5M |
| Q4 2024 | 127 | $220.1M |
| Q3 2024 | 137 | $453.1M |
| Q2 2024 | 127 | $471.0M |
| Q1 2024 | 118 | $417.8M |
| Q4 2023 | 106 | $279.8M |
| Q3 2023 | 112 | $205.8M |
| Q2 2023 | 123 | $438.2M |
| Q1 2023 | 104 | $353.8M |
| Q4 2022 | 105 | $280.5M |
| Q3 2022 | 98 | $357.3M |
| Q2 2022 | 86 | $221.0M |
| Q1 2022 | 101 | $251.3M |
| Q4 2021 | 110 | $478.9M |
| Q3 2021 | 96 | $583.0M |
| Q2 2021 | 107 | $540.2M |
| Q1 2021 | 107 | $711.5M |
Institutions, Q1 2022
Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q4 2021.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Artal Group S.A. | 71,178,364 | $148.8M | 6.29% | 00.0% | Unchanged |
| BVF Inc | 14,356,589 | $30.0M | 1.20% | −3,4110.0% | Reduced |
| FMR LLC | 5,290,549 | $11.1M | 0.00% | −377,589−6.7% | Reduced |
| BlackRock Inc. | 4,445,752 | $9.29M | 0.00% | −102,172−2.2% | Reduced |
| Vanguard Group Inc | 4,156,236 | $8.69M | 0.00% | +4,484+0.1% | Added |
| D. E. Shaw & Co., Inc. | 3,228,704 | $6.75M | 0.01% | +420,276+15.0% | Added |
| NEA Management Company, LLC | 2,382,286 | $4.98M | 0.16% | 00.0% | Unchanged |
| Pinnacle Associates Ltd | 2,094,294 | $4.38M | 0.08% | −33,368−1.6% | Reduced |
| State Street Corp | 1,324,385 | $2.77M | 0.00% | +109,367+9.0% | Added |
| Geode Capital Management, LLC | 1,257,864 | $2.63M | 0.00% | +60,125+5.0% | Added |
| JPMorgan Chase & Co | 1,129,321 | $2.36M | 0.00% | −18,769−1.6% | Reduced |
| Dimensional Fund Advisors LP | 869,611 | $1.82M | 0.00% | +96,633+12.5% | Added |
| Nomura Holdings Inc | 633,638 | $1.41M | 0.01% | +55,258+9.6% | Added |
| Northern Trust Corp | 660,406 | $1.38M | 0.00% | −27,970−4.1% | Reduced |
| Charles Schwab Investment Management Inc | 501,128 | $1.05M | 0.00% | +12,710+2.6% | Added |
| Citadel Advisors LLC | 451,812 | $945.0K | 0.00% | +418,766+1,267.2% | Added |
| Millennium Management LLC | 368,654 | $770.0K | 0.00% | +113,516+44.5% | Added |
| Fisher Asset Management, LLC | 368,194 | $770.0K | 0.00% | +197,424+115.6% | Added |
| Bank of New York Mellon Corp | 284,610 | $595.0K | 0.00% | +362+0.1% | Added |
| Nuveen Asset Management, LLC | 243,880 | $530.0K | 0.00% | +1,527+0.6% | Added |
| Russell Investments Group, Ltd. | 250,317 | $522.0K | 0.00% | 00.0% | Unchanged |
| HRT Financial LP | 242,211 | $506.0K | 0.00% | +140,650+138.5% | Added |
| Gsa Capital Partners LLP | 230,503 | $482.0K | 0.06% | +198,941+630.3% | Added |
| Wellington Management Group LLP | 217,197 | $454.0K | 0.00% | +1,656+0.8% | Added |
| UBS Group AG | 212,066 | $443.0K | 0.00% | +116,066+120.9% | Added |
| Allspring Global Investments Holdings, LLC | 203,754 | $425.0K | 0.00% | −369,745−64.5% | Reduced |
| Walleye Capital LLC | 200,968 | $420.0K | 0.01% | +200,968 | New |
| Morgan Stanley | 186,582 | $390.0K | 0.00% | +78,114+72.0% | Added |
| Goldman Sachs Group Inc | 182,671 | $381.0K | 0.00% | +25,189+16.0% | Added |
| Wells Fargo & Company | 179,952 | $376.0K | 0.00% | −312,779−63.5% | Reduced |
| Prudential Financial Inc | 169,008 | $353.0K | 0.00% | −80,700−32.3% | Reduced |
| Price T Rowe Associates Inc | 153,932 | $322.0K | 0.00% | +10,300+7.2% | Added |
| Los Angeles Capital Management LLC | 142,547 | $298.0K | 0.00% | +23,680+19.9% | Added |
| Swiss National Bank | 140,800 | $294.0K | 0.00% | +13,500+10.6% | Added |
| Tudor Investment Corp Et Al | 139,601 | $292.0K | 0.01% | −11,347−7.5% | Reduced |
| Stifel Financial Corp | 133,049 | $278.0K | 0.00% | +27,630+26.2% | Added |
| Susquehanna International Group, LLP | 115,907 | $242.0K | 0.00% | −19,869−14.6% | Reduced |
| BNP Paribas Arbitrage, SA | 106,564 | $222.7K | 0.00% | +3,220+3.1% | Added |
| Renaissance Technologies LLC | 88,776 | $186.0K | 0.00% | +88,776 | New |
| State of Wisconsin Investment Board | 87,800 | $183.0K | 0.00% | −69,700−44.3% | Reduced |
| UBS Asset Management Americas Inc | 83,874 | $175.3K | 0.00% | 00.0% | Unchanged |
| Barclays PLC | 83,237 | $175.0K | 0.00% | −1,733−2.0% | Reduced |
| Group One Trading, L.P. | 79,963 | $167.0K | 0.00% | −54,715−40.6% | Reduced |
| Rhumbline Advisers | 79,934 | $167.0K | 0.00% | −6,726−7.8% | Reduced |
| California State Teachers Retirement System | 78,726 | $165.0K | 0.00% | −7,162−8.3% | Reduced |
| Salem Investment Counselors Inc | 73,000 | $153.0K | 0.01% | 00.0% | Unchanged |
| Panagora Asset Management Inc | 53,152 | $111.0K | 0.00% | −236,327−81.6% | Reduced |
| Parametric Portfolio Associates LLC | 51,724 | $108.0K | 0.00% | −32,611−38.7% | Reduced |
| Principal Financial Group Inc | 51,855 | $108.0K | 0.00% | −18,934−26.7% | Reduced |
| Alliancebernstein L.P. | 50,411 | $105.0K | 0.00% | +300+0.6% | Added |
| AQR Capital Management LLC | 47,677 | $100.0K | 0.00% | −71,597−60.0% | Reduced |
| Bank of America Corp | 46,716 | $97.0K | 0.00% | −229,807−83.1% | Reduced |
| Credit Suisse AG | 43,150 | $90.0K | 0.00% | +406+0.9% | Added |
| Susquehanna Fundamental Investments, LLC | 42,424 | $89.0K | 0.00% | −37,431−46.9% | Reduced |
| Virtus ETF Advisers LLC | 39,262 | $82.0K | 0.04% | −2,322−5.6% | Reduced |
| Deutsche Bank AG | 37,895 | $80.0K | 0.00% | −4,516−10.6% | Reduced |
| University of Texas/Texas Am Investment Managment Co | 35,714 | $75.0K | 0.04% | 00.0% | Unchanged |
| American International Group, Inc. | 34,757 | $73.0K | 0.00% | −2,445−6.6% | Reduced |
| Manufacturers Life Insurance Company, The | 33,729 | $70.5K | 0.00% | −5,611−14.3% | Reduced |
| New York State Common Retirement Fund | 33,499 | $70.0K | 0.00% | +52+0.2% | Added |
| SG Americas Securities, LLC | 33,720 | $70.0K | 0.00% | +13,876+69.9% | Added |
| Voya Investment Management LLC | 30,980 | $65.0K | 0.00% | +1,804+6.2% | Added |
| Invesco Ltd. | 29,849 | $62.0K | 0.00% | +1,071+3.7% | Added |
| State Board of Administration of Florida Retirement System | 29,390 | $61.0K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 28,535 | $60.0K | 0.00% | −7,722−21.3% | Reduced |
| Squarepoint Ops LLC | 26,189 | $55.0K | 0.00% | −12,576−32.4% | Reduced |
| AXA S.A. | 20,900 | $43.7K | 0.00% | −54,300−72.2% | Reduced |
| Jane Street Group, LLC | 19,723 | $41.0K | 0.00% | −18,744−48.7% | Reduced |
| Parallax Volatility Advisers, L.P. | 19,265 | $40.0K | 0.00% | −16,272−45.8% | Reduced |
| Legal & General Group Plc | 17,566 | $37.0K | 0.00% | 00.0% | Unchanged |
| ExodusPoint Capital Management, LP | 16,301 | $34.0K | 0.00% | −17,600−51.9% | Reduced |
| Arizona State Retirement System | 16,100 | $34.0K | 0.00% | +546+3.5% | Added |
| Tower Research Capital LLC (TRC) | 16,265 | $34.0K | 0.00% | +8,584+111.8% | Added |
| Commonwealth Equity Services, LLC | 14,276 | $29.0K | 0.00% | 00.0% | Unchanged |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 12,688 | $27.0K | 0.00% | 00.0% | Unchanged |
| Teacher Retirement System of Texas | 12,393 | $26.0K | 0.00% | +1,492+13.7% | Added |
| Bank of Montreal | 12,000 | $26.0K | 0.00% | +12,000 | New |
| Janus Henderson Group PLC | 11,815 | $25.0K | 0.00% | +29+0.2% | Added |
| Cubist Systematic Strategies, LLC | 10,816 | $23.0K | 0.00% | −55,992−83.8% | Reduced |
| LPL Financial LLC | 11,000 | $23.0K | 0.00% | +11,000 | New |
| Berger Financial Group, Inc | 10,929 | $23.0K | 0.00% | +10,929 | New |
| Simplex Trading, LLC | 10,178 | $21.0K | 0.00% | −36,967−78.4% | Reduced |
| Victory Capital Management Inc | 11,583 | $21.0K | 0.00% | −16,368−58.6% | Reduced |
| Pegasus Asset Management, Inc. | 10,000 | $21.0K | 0.01% | 00.0% | Unchanged |
| Estabrook Capital Management | 10,000 | $20.9K | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 9,621 | $20.0K | 0.00% | −683−6.6% | Reduced |
| Amalgamated Financial Corp. | 9,621 | $20.0K | 0.00% | +9,621 | New |
| Citigroup Inc | 8,676 | $18.0K | 0.00% | −14,931−63.2% | Reduced |
| Ameritas Investment Partners, Inc. | 5,367 | $11.0K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 4,811 | $10.0K | 0.00% | −8,975−65.1% | Reduced |
| Great West Life Assurance Co | 4,635 | $10.0K | 0.00% | 00.0% | Unchanged |
| Compagnie Lombard Odier SCmA | 4,000 | $8.00K | 0.00% | 00.0% | Unchanged |
| Point72 Hong Kong Ltd | 3,603 | $8.00K | 0.00% | +3,603 | New |
| Quantbot Technologies LP | 3,625 | $7.00K | 0.00% | 00.0% | Unchanged |
| Advisor Group Holdings, Inc. | 2,482 | $4.00K | 0.00% | −77−3.0% | Reduced |
| Hall Laurie J Trustee | 1,650 | $3.00K | 0.00% | 00.0% | Unchanged |
| Farmers & Merchants Investments Inc | 1,000 | $2.00K | 0.00% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 500 | $1.00K | 0.00% | 00.0% | Unchanged |
| Daiwa Securities Group Inc. | 434 | $1.00K | 0.00% | 00.0% | Unchanged |
| Costello Asset Management, INC | 500 | $1.00K | 0.00% | 00.0% | Unchanged |