Lexicon Pharmaceuticals, Inc.
LXRX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001062822
No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.
13F holders, Q1 2023
Institutional positions in Lexicon Pharmaceuticals, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 104
- −1 vs. Q4 2022
- Shares held
- 145.6M
- −1.28M (−0.9%) vs. Q4 2022
- Total value
- $353.8M
- +$73.3M (+26.1%) vs. Q4 2022
- New holders
- 14
- 37 more added
- Sold out
- 15
- 34 more reduced
Compare with Q4 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 149 | $875.1M |
| Q1 2026 | 137 | $504.5M |
| Q4 2025 | 126 | $299.5M |
| Q3 2025 | 124 | $344.4M |
| Q2 2025 | 123 | $242.9M |
| Q1 2025 | 127 | $122.5M |
| Q4 2024 | 127 | $220.1M |
| Q3 2024 | 137 | $453.1M |
| Q2 2024 | 127 | $471.0M |
| Q1 2024 | 118 | $417.8M |
| Q4 2023 | 106 | $279.8M |
| Q3 2023 | 112 | $205.8M |
| Q2 2023 | 123 | $438.2M |
| Q1 2023 | 104 | $353.8M |
| Q4 2022 | 105 | $280.5M |
| Q3 2022 | 98 | $357.3M |
| Q2 2022 | 86 | $221.0M |
| Q1 2022 | 101 | $251.3M |
| Q4 2021 | 110 | $478.9M |
| Q3 2021 | 96 | $583.0M |
| Q2 2021 | 107 | $540.2M |
| Q1 2021 | 107 | $711.5M |
Institutions, Q1 2023
Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q4 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Artal Group S.A. | 89,778,234 | $218.2M | 12.96% | 00.0% | Unchanged |
| BVF Inc | 16,149,179 | $39.2M | 1.43% | 00.0% | Unchanged |
| BlackRock Inc. | 5,656,927 | $13.7M | 0.00% | −195,558−3.3% | Reduced |
| Vanguard Group Inc | 5,299,380 | $12.9M | 0.00% | +43,032+0.8% | Added |
| FMR LLC | 5,240,247 | $12.7M | 0.00% | −11,438−0.2% | Reduced |
| JPMorgan Chase & Co | 3,305,991 | $8.03M | 0.00% | +29,193+0.9% | Added |
| D. E. Shaw & Co., Inc. | 2,940,997 | $7.15M | 0.01% | −136,976−4.5% | Reduced |
| NEA Management Company, LLC | 2,382,286 | $5.79M | 0.40% | 00.0% | Unchanged |
| Pinnacle Associates Ltd | 1,940,224 | $4.71M | 0.10% | +7,447+0.4% | Added |
| Geode Capital Management, LLC | 1,725,409 | $4.19M | 0.00% | +117,468+7.3% | Added |
| State Street Corp | 1,564,098 | $3.80M | 0.00% | +47,623+3.1% | Added |
| Northern Trust Corp | 763,264 | $1.85M | 0.00% | −23,707−3.0% | Reduced |
| Dimensional Fund Advisors LP | 719,182 | $1.75M | 0.00% | +306,384+74.2% | Added |
| Charles Schwab Investment Management Inc | 688,611 | $1.67M | 0.00% | −7,329−1.1% | Reduced |
| Parkman Healthcare Partners LLC | 675,328 | $1.64M | 0.36% | +254,126+60.3% | Added |
| Fisher Asset Management, LLC | 649,726 | $1.58M | 0.00% | −70,517−9.8% | Reduced |
| Point72 Asset Management, L.P. | 516,367 | $1.25M | 0.00% | −827,764−61.6% | Reduced |
| ClariVest Asset Management LLC | 390,161 | $949.0K | 0.04% | +401+0.1% | Added |
| AXA S.A. | 356,400 | $866.1K | 0.00% | +335,500+1,605.3% | Added |
| Bank of New York Mellon Corp | 317,502 | $771.5K | 0.00% | −8,516−2.6% | Reduced |
| Goldman Sachs Group Inc | 288,938 | $702.1K | 0.00% | +22,581+8.5% | Added |
| Renaissance Technologies LLC | 263,875 | $641.0K | 0.00% | −129,410−32.9% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 208,333 | $506.2K | 0.00% | +73,776+54.8% | Added |
| Nuveen Asset Management, LLC | 201,514 | $489.0K | 0.00% | −43,136−17.6% | Reduced |
| Morgan Stanley | 198,304 | $481.9K | 0.00% | +62,462+46.0% | Added |
| Swiss National Bank | 162,900 | $395.8K | 0.00% | −19,400−10.6% | Reduced |
| Schonfeld Strategic Advisors LLC | 159,000 | $386.4K | 0.00% | +42,000+35.9% | Added |
| Price T Rowe Associates Inc | 156,621 | $381.0K | 0.00% | −37,492−19.3% | Reduced |
| Wellington Management Group LLP | 151,493 | $368.1K | 0.00% | −4,413−2.8% | Reduced |
| UBS Group AG | 138,726 | $337.1K | 0.00% | −21,092−13.2% | Reduced |
| UBS Asset Management Americas Inc | 137,735 | $334.7K | 0.00% | +18,689+15.7% | Added |
| Stifel Financial Corp | 128,311 | $311.8K | 0.00% | +3,827+3.1% | Added |
| Rhumbline Advisers | 125,066 | $304.0K | 0.00% | +5,949+5.0% | Added |
| Citadel Advisors LLC | 110,829 | $269.3K | 0.00% | −51,347−31.7% | Reduced |
| Prudential Financial Inc | 101,158 | $245.8K | 0.00% | +15,800+18.5% | Added |
| California State Teachers Retirement System | 97,279 | $236.4K | 0.00% | −1,960−2.0% | Reduced |
| Compagnie Lombard Odier SCmA | 94,000 | $228.4K | 0.01% | −4,000−4.1% | Reduced |
| Alliancebernstein L.P. | 93,411 | $227.0K | 0.00% | +3,600+4.0% | Added |
| Natixis Advisors, L.P. | 87,505 | $213.0K | 0.00% | +87,505 | New |
| Gsa Capital Partners LLP | 69,791 | $170.0K | 0.02% | +69,791 | New |
| State of Wisconsin Investment Board | 63,765 | $154.9K | 0.00% | −7,078−10.0% | Reduced |
| Credit Suisse AG | 63,385 | $154.0K | 0.00% | +200.0% | Added |
| Bank of America Corp | 60,761 | $147.6K | 0.00% | −1,710−2.7% | Reduced |
| Qube Research & Technologies Ltd | 60,723 | $147.6K | 0.00% | +60,723 | New |
| Russell Investments Group, Ltd. | 55,327 | $134.4K | 0.00% | −193,087−77.7% | Reduced |
| Great West Life Assurance Co | 54,172 | $131.0K | 0.00% | +49,537+1,068.8% | Added |
| Susquehanna International Group, LLP | 53,293 | $129.5K | 0.00% | +4,438+9.1% | Added |
| Deutsche Bank AG | 52,625 | $127.9K | 0.00% | +15,979+43.6% | Added |
| Captrust Financial Advisors | 46,489 | $113.0K | 0.00% | +46,489 | New |
| Simplex Trading, LLC | 45,624 | $110.0K | 0.00% | +28,416+165.1% | Added |
| Jane Street Group, LLC | 43,523 | $105.8K | 0.00% | +26,192+151.1% | Added |
| MetLife Investment Management | 42,834 | $104.1K | 0.00% | +20,999+96.2% | Added |
| Barclays PLC | 42,296 | $102.8K | 0.00% | +19,936+89.2% | Added |
| Invesco Ltd. | 40,972 | $99.6K | 0.00% | −251−0.6% | Reduced |
| Principal Financial Group Inc | 40,544 | $98.5K | 0.00% | −667−1.6% | Reduced |
| American International Group, Inc. | 40,193 | $97.7K | 0.00% | +800+2.0% | Added |
| SG Americas Securities, LLC | 37,689 | $92.0K | 0.00% | +12,636+50.4% | Added |
| Manufacturers Life Insurance Company, The | 35,943 | $87.3K | 0.00% | 00.0% | Unchanged |
| University of Texas/Texas Am Investment Managment Co | 35,714 | $87.0K | 0.03% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 33,626 | $81.7K | 0.00% | 00.0% | Unchanged |
| Group One Trading, L.P. | 33,513 | $81.4K | 0.00% | +9,289+38.3% | Added |
| Voya Investment Management LLC | 32,681 | $79.4K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 30,056 | $73.0K | 0.00% | +3,403+12.8% | Added |
| CIBC Private Wealth Group, LLC | 30,000 | $72.9K | 0.00% | 00.0% | Unchanged |
| State Board of Administration of Florida Retirement System | 29,400 | $71.4K | 0.00% | 00.0% | Unchanged |
| Janus Henderson Group PLC | 28,630 | $69.4K | 0.00% | +17,269+152.0% | Added |
| Squarepoint Ops LLC | 23,938 | $58.2K | 0.00% | −3,326−12.2% | Reduced |
| Millennium Management LLC | 23,844 | $58.0K | 0.00% | −1,152,723−98.0% | Reduced |
| Teacher Retirement System of Texas | 23,255 | $57.0K | 0.00% | +389+1.7% | Added |
| ProShare Advisors LLC | 22,886 | $55.6K | 0.00% | −3,438−13.1% | Reduced |
| Arizona State Retirement System | 21,873 | $53.2K | 0.00% | +572+2.7% | Added |
| Virtu Financial LLC | 21,729 | $53.0K | 0.01% | +21,729 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 20,787 | $50.5K | 0.00% | −15,693−43.0% | Reduced |
| LPL Financial LLC | 20,732 | $50.4K | 0.00% | 00.0% | Unchanged |
| Victory Capital Management Inc | 20,723 | $50.4K | 0.00% | +300+1.5% | Added |
| Traynor Capital Management, Inc. | 19,064 | $46.3K | 0.01% | +19,064 | New |
| BNP Paribas Arbitrage, SA | 18,552 | $45.1K | 0.00% | +10,312+125.1% | Added |
| Jump Financial, LLC | 18,200 | $44.2K | 0.00% | +18,200 | New |
| ExodusPoint Capital Management, LP | 15,536 | $38.0K | 0.00% | +15,536 | New |
| Wells Fargo & Company | 15,363 | $37.3K | 0.00% | +15,363 | New |
| Hudson Capital Management LLC | 15,038 | $36.5K | 0.01% | +15,038 | New |
| Beacon Pointe Advisors, LLC | 15,000 | $36.5K | 0.00% | +15,000 | New |
| Commonwealth Equity Services, LLC | 14,069 | $34.0K | 0.00% | −10,400−42.5% | Reduced |
| Pinnacle Wealth Management Advisory Group, LLC | 11,385 | $27.7K | 0.00% | +965+9.3% | Added |
| Tudor Investment Corp Et Al | 11,000 | $27.0K | 0.00% | +11,000 | New |
| Berger Financial Group, Inc | 10,929 | $26.6K | 0.00% | 00.0% | Unchanged |
| Estabrook Capital Management | 10,000 | $24.3K | 0.00% | 00.0% | Unchanged |
| Pegasus Asset Management, Inc. | 10,000 | $24.3K | 0.01% | 00.0% | Unchanged |
| Amalgamated Bank | 9,111 | $22.0K | 0.00% | −1,926−17.5% | Reduced |
| Cubist Systematic Strategies, LLC | 5,922 | $14.4K | 0.00% | −12,323−67.5% | Reduced |
| Ameritas Investment Partners, Inc. | 5,367 | $13.0K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 5,611 | $13.0K | 0.00% | −713−11.3% | Reduced |
| Metropolitan Life Insurance Co | 4,595 | $11.2K | 0.00% | −610−11.7% | Reduced |
| Royal Bank of Canada | 4,660 | $11.0K | 0.00% | −7,960−63.1% | Reduced |
| Citigroup Inc | 4,045 | $9.83K | 0.00% | −172−4.1% | Reduced |
| Advisor Group Holdings, Inc. | 2,882 | $7.00K | 0.00% | −392−12.0% | Reduced |
| China Universal Asset Management Co., Ltd. | 2,557 | $6.21K | 0.00% | +639+33.3% | Added |
| Quintet Private Bank (Europe) S.A. | 1,930 | $4.69K | 0.00% | +1,930 | New |
| Global Retirement Partners, LLC | 1,000 | $2.74K | 0.00% | +1,000 | New |
| Northwestern Mutual Wealth Management Co | 500 | $1.22K | 0.00% | 00.0% | Unchanged |