Skip to main content

Lexicon Pharmaceuticals, Inc.

LXRX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001062822

No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.

13F holders, Q3 2023

Institutional positions in Lexicon Pharmaceuticals, Inc. as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
112
−10 vs. Q2 2023
Shares held
188.8M
−2.51M (−1.3%) vs. Q2 2023
Total value
$205.8M
−$232.3M (−53.0%) vs. Q2 2023
New holders
11
44 more added
Sold out
21
30 more reduced

1 institution that held it in Q2 2023 haven't filed for Q3 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2023: 112 institutions
Q1 2021: 107 institutionsQ2 2021: 107 institutionsQ3 2021: 96 institutionsQ4 2021: 110 institutionsQ1 2022: 101 institutionsQ2 2022: 86 institutionsQ3 2022: 98 institutionsQ4 2022: 105 institutionsQ1 2023: 104 institutionsQ2 2023: 123 institutionsQ3 2023: 112 institutionsQ4 2023: 106 institutionsQ1 2024: 118 institutionsQ2 2024: 127 institutionsQ3 2024: 137 institutionsQ4 2024: 127 institutionsQ1 2025: 127 institutionsQ2 2025: 123 institutionsQ3 2025: 124 institutionsQ4 2025: 126 institutionsQ1 2026: 137 institutionsQ2 2026: 149 institutions
Value heldQ3 2023: $205.8M
Q1 2021: $711.5MQ2 2021: $540.2MQ3 2021: $583.0MQ4 2021: $478.9MQ1 2022: $251.3MQ2 2022: $221.0MQ3 2022: $357.3MQ4 2022: $280.5MQ1 2023: $353.8MQ2 2023: $438.2MQ3 2023: $205.8MQ4 2023: $279.8MQ1 2024: $417.8MQ2 2024: $471.0MQ3 2024: $453.1MQ4 2024: $220.1MQ1 2025: $122.5MQ2 2025: $242.9MQ3 2025: $344.4MQ4 2025: $299.5MQ1 2026: $504.5MQ2 2026: $875.1M
Institutions holding LXRX and their total value by quarter
QuarterHoldersValue
Q2 2026149$875.1M
Q1 2026137$504.5M
Q4 2025126$299.5M
Q3 2025124$344.4M
Q2 2025123$242.9M
Q1 2025127$122.5M
Q4 2024127$220.1M
Q3 2024137$453.1M
Q2 2024127$471.0M
Q1 2024118$417.8M
Q4 2023106$279.8M
Q3 2023112$205.8M
Q2 2023123$438.2M
Q1 2023104$353.8M
Q4 2022105$280.5M
Q3 202298$357.3M
Q2 202286$221.0M
Q1 2022101$251.3M
Q4 2021110$478.9M
Q3 202196$583.0M
Q2 2021107$540.2M
Q1 2021107$711.5M

Institutions, Q3 2023

Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q2 2023.

Institutions holding LXRX in Q3 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Artal Group S.A.117,553,284$128.1M5.59%00.0%Unchanged
BVF Inc19,995,332$21.8M0.59%00.0%Unchanged
FMR LLC7,563,076$8.24M0.00%−947,992−11.1%Reduced
BlackRock Inc.6,654,966$7.25M0.00%+275,780+4.3%Added
Vanguard Group Inc6,400,211$6.98M0.00%−56,741−0.9%Reduced
Millennium Management LLC3,885,753$4.24M0.00%+1,251,580+47.5%Added
JPMorgan Chase & Co2,815,034$3.07M0.00%−116,135−4.0%Reduced
NEA Management Company, LLC2,382,286$2.60M0.20%00.0%Unchanged
Geode Capital Management, LLC2,126,137$2.32M0.00%+285,700+15.5%Added
Octagon Capital Advisors LP1,923,076$2.10M0.37%00.0%Unchanged
Pinnacle Associates Ltd1,912,869$2.09M0.04%−80,758−4.1%Reduced
State Street Corp1,876,139$2.04M0.00%+146,027+8.4%Added
Ameriprise Financial Inc1,214,678$1.32M0.00%+376,270+44.9%Added
Northern Trust Corp1,150,817$1.25M0.00%+68,986+6.4%Added
Parkman Healthcare Partners LLC1,136,413$1.24M0.23%−194,203−14.6%Reduced
Charles Schwab Investment Management Inc851,921$928.6K0.00%+139,546+19.6%Added
D. E. Shaw & Co., Inc.784,122$854.7K0.00%−429,604−35.4%Reduced
Two Sigma Investments, LP645,368$703.5K0.00%+517,726+405.6%Added
Alyeska Investment Group, L.P.509,484$555.3K0.00%−1,232,868−70.8%Reduced
Schonfeld Strategic Advisors LLC469,666$511.9K0.00%−23,476−4.8%Reduced
Nuveen Asset Management, LLC409,179$446.0K0.00%+89,985+28.2%Added
Wellington Management Group LLP378,701$412.8K0.00%+236,695+166.7%Added
Goldman Sachs Group Inc359,711$392.1K0.00%−193,297−35.0%Reduced
Connor, Clark & Lunn Investment Management Ltd.337,064$367.4K0.00%+2,813+0.8%Added
Bank of New York Mellon Corp331,323$361.1K0.00%−6,352−1.9%Reduced
Susquehanna International Group, LLP328,506$358.1K0.00%−6,951−2.1%Reduced
Dimensional Fund Advisors LP310,815$338.8K0.00%−432,922−58.2%Reduced
Qube Research & Technologies Ltd277,248$302.2K0.00%+204,005+278.5%Added
Renaissance Technologies LLC272,255$297.0K0.00%+272,255New
Alliancebernstein L.P.245,301$267.4K0.00%+18,190+8.0%Added
Swiss National Bank242,300$264.1K0.00%+10,300+4.4%Added
Morgan Stanley239,620$261.2K0.00%−34,923−12.7%Reduced
ClariVest Asset Management LLC192,398$210.0K0.01%−318,976−62.4%Reduced
Bank of America Corp164,476$179.3K0.00%+86,184+110.1%Added
Credit Suisse AG145,746$158.9K0.00%−5,694−3.8%Reduced
UBS Asset Management Americas Inc137,735$150.1K0.00%00.0%Unchanged
Rhumbline Advisers130,291$142.0K0.00%−9,456−6.8%Reduced
UBS Group AG125,362$136.6K0.00%+27,799+28.5%Added
Virtus ETF Advisers LLC121,711$132.7K0.08%−15,739−11.5%Reduced
BNP Paribas Arbitrage, SA120,572$131.4K0.00%+95,432+379.6%Added
California State Teachers Retirement System117,883$128.5K0.00%−6,683−5.4%Reduced
Price T Rowe Associates Inc100,691$110.0K0.00%−7,695−7.1%Reduced
Compagnie Lombard Odier SCmA94,000$102.5K0.00%00.0%Unchanged
Verition Fund Management LLC91,700$100.0K0.00%+18,400+25.1%Added
Legal & General Group Plc83,635$91.2K0.00%−19,946−19.3%Reduced
Stifel Financial Corp81,967$89.3K0.00%−46,952−36.4%Reduced
Jane Street Group, LLC81,930$89.3K0.00%+61,382+298.7%Added
Squarepoint Ops LLC62,243$67.8K0.00%+62,243New
State of Wisconsin Investment Board62,077$67.7K0.00%+553+0.9%Added
SG Americas Securities, LLC58,707$64.0K0.00%+58,707New
Invesco Ltd.51,937$56.6K0.00%+11,820+29.5%Added
Russell Investments Group, Ltd.49,100$53.5K0.00%−6,227−11.3%Reduced
Tudor Investment Corp Et Al47,101$51.3K0.00%−1,484−3.1%Reduced
American International Group, Inc.46,235$50.4K0.00%+1,644+3.7%Added
Captrust Financial Advisors44,618$48.6K0.00%−1,871−4.0%Reduced
MetLife Investment Management42,834$46.7K0.00%00.0%Unchanged
Manufacturers Life Insurance Company, The42,487$46.3K0.00%+1,319+3.2%Added
Deutsche Bank AG40,289$43.9K0.00%00.0%Unchanged
Commonwealth Equity Services, LLC39,569$43.0K0.00%+24,400+160.9%Added
Barclays PLC39,189$42.7K0.00%+1,520+4.0%Added
Voya Investment Management LLC37,359$40.7K0.00%00.0%Unchanged
Citigroup Inc36,015$39.3K0.00%+2,528+7.5%Added
University of Texas/Texas Am Investment Managment Co35,714$38.9K0.02%00.0%Unchanged
Two Sigma Advisers, LP34,844$38.0K0.00%+34,844New
New York State Common Retirement Fund33,876$36.9K0.00%+350+1.0%Added
Prosperity Financial Group, Inc.31,500$34.3K0.03%+5,500+21.2%Added
Arizona State Retirement System31,372$34.2K0.00%+7,518+31.5%Added
Teacher Retirement System of Texas30,937$34.0K0.00%+2,122+7.4%Added
Point72 Middle East FZE29,615$32.3K0.00%+990+3.5%Added
AQR Capital Management LLC29,558$32.2K0.00%+1,501+5.3%Added
Janus Henderson Group PLC29,470$32.0K0.00%+335+1.1%Added
ProShare Advisors LLC28,049$30.6K0.00%+3,734+15.4%Added
Tiaa Trust, National Association27,000$29.4K0.00%+27,000New
LPL Financial LLC26,994$29.4K0.00%+2,007+8.0%Added
Victory Capital Management Inc26,374$28.7K0.00%+6,123+30.2%Added
Beacon Pointe Advisors, LLC22,800$24.9K0.00%−6,700−22.7%Reduced
Traynor Capital Management, Inc.21,909$23.9K0.00%+1,103+5.3%Added
Wells Fargo & Company21,164$23.1K0.00%−15,661−42.5%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)20,787$22.7K0.00%00.0%Unchanged
Wolverine Trading, LLC17,414$19.0K0.00%−3,275−15.8%Reduced
Tower Research Capital LLC (TRC)16,930$18.5K0.00%−27,648−62.0%Reduced
Federated Hermes, Inc.16,493$18.0K0.00%+6,925+72.4%Added
Hudson Capital Management LLC15,038$16.4K0.01%00.0%Unchanged
Cambridge Investment Research Advisors, Inc.14,239$16.0K0.00%+14,239New
Royal Bank of Canada13,778$15.0K0.00%+5,871+74.3%Added
Pinnacle Wealth Management Advisory Group, LLC12,135$13.2K0.00%00.0%Unchanged
Truist Financial Corp12,000$13.1K0.00%+12,000New
Chemistry Wealth Management LLC12,000$13.1K0.00%+12,000New
Amalgamated Bank10,664$12.0K0.00%00.0%Unchanged
Berger Financial Group, Inc10,929$11.9K0.00%00.0%Unchanged
Raymond James & Associates10,841$11.8K0.00%−232−2.1%Reduced
Principal Financial Group Inc10,333$11.3K0.00%00.0%Unchanged
Estabrook Capital Management10,000$10.9K0.00%00.0%Unchanged
LifeSteps Financial, Inc.10,000$10.9K0.01%00.0%Unchanged
Covestor Ltd8,385$9.00K0.01%00.0%Unchanged
Advisor Group Holdings, Inc.7,244$7.89K0.00%+876+13.8%Added
China Universal Asset Management Co., Ltd.6,286$6.85K0.00%+3,801+153.0%Added
Ameritas Investment Partners, Inc.5,367$5.85K0.00%00.0%Unchanged
Metropolitan Life Insurance Co4,595$5.01K0.00%00.0%Unchanged
Great West Life Assurance Co4,635$5.00K0.00%00.0%Unchanged