Lexicon Pharmaceuticals, Inc.
LXRX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001062822
No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.
13F holders, Q4 2022
Institutional positions in Lexicon Pharmaceuticals, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 105
- +7 vs. Q3 2022
- Shares held
- 146.9M
- −1.99M (−1.3%) vs. Q3 2022
- Total value
- $280.5M
- −$76.8M (−21.5%) vs. Q3 2022
- New holders
- 14
- 38 more added
- Sold out
- 7
- 31 more reduced
Compare with Q3 2022: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 149 | $875.1M |
| Q1 2026 | 137 | $504.5M |
| Q4 2025 | 126 | $299.5M |
| Q3 2025 | 124 | $344.4M |
| Q2 2025 | 123 | $242.9M |
| Q1 2025 | 127 | $122.5M |
| Q4 2024 | 127 | $220.1M |
| Q3 2024 | 137 | $453.1M |
| Q2 2024 | 127 | $471.0M |
| Q1 2024 | 118 | $417.8M |
| Q4 2023 | 106 | $279.8M |
| Q3 2023 | 112 | $205.8M |
| Q2 2023 | 123 | $438.2M |
| Q1 2023 | 104 | $353.8M |
| Q4 2022 | 105 | $280.5M |
| Q3 2022 | 98 | $357.3M |
| Q2 2022 | 86 | $221.0M |
| Q1 2022 | 101 | $251.3M |
| Q4 2021 | 110 | $478.9M |
| Q3 2021 | 96 | $583.0M |
| Q2 2021 | 107 | $540.2M |
| Q1 2021 | 107 | $711.5M |
Institutions, Q4 2022
Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q3 2022.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Artal Group S.A. | 89,778,234 | $171.5M | 9.88% | 00.0% | Unchanged |
| BVF Inc | 16,149,179 | $30.8M | 1.30% | 00.0% | Unchanged |
| BlackRock Inc. | 5,852,485 | $11.2M | 0.00% | +92,485+1.6% | Added |
| Vanguard Group Inc | 5,256,348 | $10.0M | 0.00% | +600.0% | Added |
| FMR LLC | 5,251,685 | $10.0M | 0.00% | −31,314−0.6% | Reduced |
| JPMorgan Chase & Co | 3,276,798 | $6.26M | 0.00% | +50,365+1.6% | Added |
| D. E. Shaw & Co., Inc. | 3,077,973 | $5.88M | 0.01% | +33,996+1.1% | Added |
| NEA Management Company, LLC | 2,382,286 | $4.55M | 0.26% | 00.0% | Unchanged |
| Pinnacle Associates Ltd | 1,932,777 | $3.69M | 0.08% | −98,430−4.8% | Reduced |
| Geode Capital Management, LLC | 1,607,941 | $3.07M | 0.00% | +38,919+2.5% | Added |
| State Street Corp | 1,516,475 | $2.90M | 0.00% | +52,906+3.6% | Added |
| Point72 Asset Management, L.P. | 1,344,131 | $2.57M | 0.01% | −2,269,369−62.8% | Reduced |
| Millennium Management LLC | 1,176,567 | $2.25M | 0.00% | +270,656+29.9% | Added |
| Northern Trust Corp | 786,971 | $1.50M | 0.00% | +51,461+7.0% | Added |
| Fisher Asset Management, LLC | 720,243 | $1.38M | 0.00% | +114,715+18.9% | Added |
| Charles Schwab Investment Management Inc | 695,940 | $1.33M | 0.00% | +33,462+5.1% | Added |
| Parkman Healthcare Partners LLC | 421,202 | $804.5K | 0.21% | +117,588+38.7% | Added |
| Dimensional Fund Advisors LP | 412,798 | $788.0K | 0.00% | −50,390−10.9% | Reduced |
| Renaissance Technologies LLC | 393,285 | $751.0K | 0.00% | −88,090−18.3% | Reduced |
| ClariVest Asset Management LLC | 389,760 | $744.0K | 0.04% | −3,031−0.8% | Reduced |
| Bank of New York Mellon Corp | 326,018 | $622.7K | 0.00% | +34,358+11.8% | Added |
| Goldman Sachs Group Inc | 266,357 | $508.7K | 0.00% | +25,436+10.6% | Added |
| Russell Investments Group, Ltd. | 248,414 | $474.5K | 0.00% | 00.0% | Unchanged |
| Nuveen Asset Management, LLC | 244,650 | $467.0K | 0.00% | −61,866−20.2% | Reduced |
| Price T Rowe Associates Inc | 194,113 | $371.0K | 0.00% | +838+0.4% | Added |
| Swiss National Bank | 182,300 | $348.2K | 0.00% | +9,500+5.5% | Added |
| Citadel Advisors LLC | 162,176 | $309.8K | 0.00% | +34,983+27.5% | Added |
| UBS Group AG | 159,818 | $305.3K | 0.00% | +66,132+70.6% | Added |
| Wellington Management Group LLP | 155,906 | $297.8K | 0.00% | +263+0.2% | Added |
| Morgan Stanley | 135,842 | $259.5K | 0.00% | −33,241−19.7% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 134,557 | $257.0K | 0.00% | +134,557 | New |
| Stifel Financial Corp | 124,484 | $237.8K | 0.00% | −12,199−8.9% | Reduced |
| Rhumbline Advisers | 119,117 | $228.0K | 0.00% | +5,722+5.0% | Added |
| UBS Asset Management Americas Inc | 119,046 | $227.4K | 0.00% | 00.0% | Unchanged |
| Schonfeld Strategic Advisors LLC | 117,000 | $223.5K | 0.00% | +117,000 | New |
| Two Sigma Investments, LP | 115,231 | $220.1K | 0.00% | +71,934+166.1% | Added |
| California State Teachers Retirement System | 99,239 | $189.5K | 0.00% | +3,179+3.3% | Added |
| Compagnie Lombard Odier SCmA | 98,000 | $187.0K | 0.01% | 00.0% | Unchanged |
| Alliancebernstein L.P. | 89,811 | $171.5K | 0.00% | +4,800+5.6% | Added |
| Prudential Financial Inc | 85,358 | $163.0K | 0.00% | 00.0% | Unchanged |
| State of Wisconsin Investment Board | 70,843 | $135.3K | 0.00% | −4,244−5.7% | Reduced |
| Credit Suisse AG | 63,365 | $121.0K | 0.00% | +23,882+60.5% | Added |
| Bank of America Corp | 62,471 | $119.3K | 0.00% | −47,662−43.3% | Reduced |
| Susquehanna International Group, LLP | 48,855 | $93.3K | 0.00% | −30,497−38.4% | Reduced |
| AQR Capital Management LLC | 47,014 | $89.8K | 0.00% | −253,205−84.3% | Reduced |
| Caxton Associates LP | 46,281 | $88.4K | 0.01% | −8,500−15.5% | Reduced |
| Invesco Ltd. | 41,223 | $78.7K | 0.00% | +9,870+31.5% | Added |
| Principal Financial Group Inc | 41,211 | $78.7K | 0.00% | +31,205+311.9% | Added |
| American International Group, Inc. | 39,393 | $75.2K | 0.00% | −143−0.4% | Reduced |
| Balyasny Asset Management LLC | 38,377 | $73.3K | 0.00% | +38,377 | New |
| Deutsche Bank AG | 36,646 | $70.0K | 0.00% | +556+1.5% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 36,480 | $69.7K | 0.00% | +23,792+187.5% | Added |
| Manufacturers Life Insurance Company, The | 35,943 | $68.7K | 0.00% | +20,065+126.4% | Added |
| University of Texas/Texas Am Investment Managment Co | 35,714 | $68.0K | 0.03% | 00.0% | Unchanged |
| New York State Common Retirement Fund | 33,626 | $64.2K | 0.00% | +87+0.3% | Added |
| Voya Investment Management LLC | 32,681 | $62.4K | 0.00% | 00.0% | Unchanged |
| State Board of Administration of Florida Retirement System | 29,400 | $56.2K | 0.00% | 00.0% | Unchanged |
| Squarepoint Ops LLC | 27,264 | $52.1K | 0.00% | +27,264 | New |
| Legal & General Group Plc | 26,653 | $50.9K | 0.00% | 00.0% | Unchanged |
| ProShare Advisors LLC | 26,324 | $50.3K | 0.00% | +1,699+6.9% | Added |
| SG Americas Securities, LLC | 25,053 | $48.0K | 0.00% | −9,536−27.6% | Reduced |
| Group One Trading, L.P. | 24,224 | $46.3K | 0.00% | −105,048−81.3% | Reduced |
| Commonwealth Equity Services, LLC | 24,469 | $46.0K | 0.00% | −107−0.4% | Reduced |
| Teacher Retirement System of Texas | 22,866 | $44.0K | 0.00% | −1,230−5.1% | Reduced |
| Barclays PLC | 22,360 | $42.7K | 0.00% | +18,829+533.2% | Added |
| MetLife Investment Management | 21,835 | $41.7K | 0.00% | −18,221−45.5% | Reduced |
| Arizona State Retirement System | 21,301 | $40.7K | 0.00% | +1,344+6.7% | Added |
| AXA S.A. | 20,900 | $39.9K | 0.00% | −91,268−81.4% | Reduced |
| LPL Financial LLC | 20,732 | $39.6K | 0.00% | +32+0.2% | Added |
| Victory Capital Management Inc | 20,423 | $39.0K | 0.00% | −100.0% | Reduced |
| Cubist Systematic Strategies, LLC | 18,245 | $34.8K | 0.00% | −4,600−20.1% | Reduced |
| Jane Street Group, LLC | 17,331 | $33.1K | 0.00% | −17,210−49.8% | Reduced |
| Acrisure Capital Management, LLC | 16,861 | $32.2K | 0.04% | +16,861 | New |
| Simplex Trading, LLC | 17,208 | $32.0K | 0.00% | +2,373+16.0% | Added |
| Royal Bank of Canada | 12,620 | $24.0K | 0.00% | +11,585+1,119.3% | Added |
| Janus Henderson Group PLC | 11,361 | $21.6K | 0.00% | 00.0% | Unchanged |
| Amalgamated Bank | 11,037 | $21.0K | 0.00% | 00.0% | Unchanged |
| Berger Financial Group, Inc | 10,929 | $20.9K | 0.00% | 00.0% | Unchanged |
| Pinnacle Wealth Management Advisory Group, LLC | 10,420 | $19.9K | 0.00% | +280+2.8% | Added |
| Estabrook Capital Management | 10,000 | $19.1K | 0.00% | 00.0% | Unchanged |
| Pegasus Asset Management, Inc. | 10,000 | $19.1K | 0.01% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 8,240 | $15.7K | 0.00% | −7,219−46.7% | Reduced |
| Allspring Global Investments Holdings, LLC | 8,160 | $15.6K | 0.00% | −179−2.1% | Reduced |
| Ameritas Investment Partners, Inc. | 5,367 | $12.0K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 6,324 | $12.0K | 0.00% | −13,065−67.4% | Reduced |
| Metropolitan Life Insurance Co | 5,205 | $9.94K | 0.00% | +111+2.2% | Added |
| Point72 Middle East FZE | 5,167 | $9.87K | 0.00% | +5,167 | New |
| Great West Life Assurance Co | 4,635 | $9.00K | 0.00% | −32,708−87.6% | Reduced |
| Citigroup Inc | 4,217 | $8.05K | 0.00% | −420−9.1% | Reduced |
| Aquatic Capital Management LLC | 4,000 | $8.00K | 0.00% | +4,000 | New |
| Advisor Group Holdings, Inc. | 3,274 | $6.00K | 0.00% | −340−9.4% | Reduced |
| Rockefeller Capital Management L.P. | 3,000 | $5.00K | 0.00% | +3,000 | New |
| China Universal Asset Management Co., Ltd. | 1,918 | $3.66K | 0.00% | +199+11.6% | Added |
| Farmers & Merchants Investments Inc | 1,000 | $1.91K | 0.00% | 00.0% | Unchanged |
| Hall Laurie J Trustee | 720 | $1.00K | 0.00% | −420−36.8% | Reduced |
| Daiwa Securities Group Inc. | 434 | $1.00K | 0.00% | 00.0% | Unchanged |
| Northwestern Mutual Wealth Management Co | 500 | $955 | 0.00% | 00.0% | Unchanged |
| Advisory Services Network, LLC | 242 | $462 | 0.00% | +242 | New |
| Coppell Advisory Solutions LLC | 113 | $216 | 0.00% | +113 | New |
| Coppell Advisory Solutions Corp. | 113 | $216 | 0.00% | +113 | New |