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Lexicon Pharmaceuticals, Inc.

LXRX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001062822

No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.

13F holders, Q1 2024

Institutional positions in Lexicon Pharmaceuticals, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
118
+13 vs. Q4 2023
Shares held
172.8M
−10.0M (−5.5%) vs. Q4 2023
Total value
$417.8M
+$138.0M (+49.3%) vs. Q4 2023
New holders
33
31 more added
Sold out
20
31 more reduced

1 institution that held it in Q4 2023 haven't filed for Q1 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting LXRX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 118 institutions
Q1 2021: 107 institutionsQ2 2021: 107 institutionsQ3 2021: 96 institutionsQ4 2021: 110 institutionsQ1 2022: 101 institutionsQ2 2022: 86 institutionsQ3 2022: 98 institutionsQ4 2022: 105 institutionsQ1 2023: 104 institutionsQ2 2023: 123 institutionsQ3 2023: 112 institutionsQ4 2023: 106 institutionsQ1 2024: 118 institutionsQ2 2024: 127 institutionsQ3 2024: 137 institutionsQ4 2024: 127 institutionsQ1 2025: 127 institutionsQ2 2025: 123 institutionsQ3 2025: 124 institutionsQ4 2025: 126 institutionsQ1 2026: 137 institutionsQ2 2026: 149 institutions
Value heldQ1 2024: $417.8M
Q1 2021: $711.5MQ2 2021: $540.2MQ3 2021: $583.0MQ4 2021: $478.9MQ1 2022: $251.3MQ2 2022: $221.0MQ3 2022: $357.3MQ4 2022: $280.5MQ1 2023: $353.8MQ2 2023: $438.2MQ3 2023: $205.8MQ4 2023: $279.8MQ1 2024: $417.8MQ2 2024: $471.0MQ3 2024: $453.1MQ4 2024: $220.1MQ1 2025: $122.5MQ2 2025: $242.9MQ3 2025: $344.4MQ4 2025: $299.5MQ1 2026: $504.5MQ2 2026: $875.1M
Institutions holding LXRX and their total value by quarter
QuarterHoldersValue
Q2 2026149$875.1M
Q1 2026137$504.5M
Q4 2025126$299.5M
Q3 2025124$344.4M
Q2 2025123$242.9M
Q1 2025127$122.5M
Q4 2024127$220.1M
Q3 2024137$453.1M
Q2 2024127$471.0M
Q1 2024118$417.8M
Q4 2023106$279.8M
Q3 2023112$205.8M
Q2 2023123$438.2M
Q1 2023104$353.8M
Q4 2022105$280.5M
Q3 202298$357.3M
Q2 202286$221.0M
Q1 2022101$251.3M
Q4 2021110$478.9M
Q3 202196$583.0M
Q2 2021107$540.2M
Q1 2021107$711.5M

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Lexicon Pharmaceuticals, Inc.; share changes are against Q4 2023.

Institutions holding LXRX in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Artal Group S.A.117,553,284$282.1M7.27%00.0%Unchanged
FMR LLC13,894,062$33.3M0.00%+11,617,594+510.3%Added
BlackRock Inc.7,693,277$18.5M0.00%+688,124+9.8%Added
Vanguard Group Inc6,401,225$15.4M0.00%+420,854+7.0%Added
OrbiMed Advisors LLC3,542,000$8.50M0.17%+3,542,000New
Geode Capital Management, LLC2,389,137$5.73M0.00%+40,221+1.7%Added
NEA Management Company, LLC2,382,286$5.72M0.35%00.0%Unchanged
Schonfeld Strategic Advisors LLC960,150$5.35M0.04%+960,150New
State Street Corp1,987,510$4.77M0.00%+95,191+5.0%Added
Pinnacle Associates Ltd1,747,830$4.19M0.07%+17,009+1.0%Added
BVF Inc1,686,924$4.05M0.11%−22,748,708−93.1%Reduced
Ameriprise Financial Inc1,417,950$3.40M0.00%−472,250−25.0%Reduced
Cubist Systematic Strategies, LLC1,404,928$3.37M0.04%+1,404,928New
Charles Schwab Investment Management Inc881,123$2.11M0.00%+16,948+2.0%Added
Northern Trust Corp866,556$2.08M0.00%+6,968+0.8%Added
Wellington Management Group LLP686,418$1.65M0.00%+686,418New
Point72 Asset Management, L.P.584,386$1.40M0.00%+584,386New
Millennium Management LLC534,184$1.28M0.00%−1,098,992−67.3%Reduced
Nuveen Asset Management, LLC524,177$1.26M0.00%+113,131+27.5%Added
Marshall Wace, LLP499,172$1.20M0.00%+499,172New
ExodusPoint Capital Management, LP319,058$766.0K0.01%+319,058New
Gsa Capital Partners LLP293,333$704.0K0.06%−486,744−62.4%Reduced
Virtus ETF Advisers LLC293,092$703.4K0.37%+42,169+16.8%Added
Bank of New York Mellon Corp292,006$700.8K0.00%−49,071−14.4%Reduced
Jane Street Group, LLC281,588$675.8K0.00%+9,221+3.4%Added
Boulder Hill Capital Management LP256,400$615.4K0.25%+256,400New
Morgan Stanley244,209$586.1K0.00%−673,479−73.4%Reduced
Alliancebernstein L.P.219,941$527.9K0.00%−25,360−10.3%Reduced
Two Sigma Investments, LP189,431$454.6K0.00%−13,456−6.6%Reduced
UBS Group AG166,961$400.7K0.00%−2,655−1.6%Reduced
Goldman Sachs Group Inc156,214$374.9K0.00%−79,125−33.6%Reduced
Rhumbline Advisers134,845$323.6K0.00%+4,554+3.5%Added
Citadel Advisors LLC134,477$322.7K0.00%−651,683−82.9%Reduced
Price T Rowe Associates Inc105,315$253.0K0.00%+4,624+4.6%Added
Commonwealth Equity Services, LLC95,184$228.0K0.00%+61,000+178.4%Added
Compagnie Lombard Odier SCmA94,000$225.6K0.00%00.0%Unchanged
JPMorgan Chase & Co90,136$216.3K0.00%−2,953,155−97.0%Reduced
LPL Financial LLC89,963$215.9K0.00%+45,969+104.5%Added
Natixis Advisors, L.P.86,094$207.0K0.00%+86,094New
Bank of America Corp85,872$206.1K0.00%−124,853−59.2%Reduced
Barclays PLC64,619$155.1K0.00%−62,397−49.1%Reduced
Pathstone Holdings, LLC62,725$150.5K0.00%+28,280+82.1%Added
BNP Paribas Arbitrage, SA59,378$142.5K0.00%+26,859+82.6%Added
University of Texas/Texas Am Investment Managment Co71,428$140.4K0.02%+35,714+100.0%Added
Stifel Financial Corp52,174$125.2K0.00%+12,522+31.6%Added
Dimensional Fund Advisors LP49,943$119.9K0.00%+49,943New
Invesco Ltd.49,818$119.6K0.00%−11,364−18.6%Reduced
Lazard Freres Gestion S.A.S.50,000$119.0K0.00%+50,000New
Russell Investments Group, Ltd.49,100$117.8K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.46,930$112.6K0.01%+18,601+65.7%Added
American International Group, Inc.45,658$109.6K0.00%−391−0.8%Reduced
Virtu Financial LLC43,591$105.0K0.01%+43,591New
Wedbush Securities Inc41,650$100.0K0.00%+41,650New
KWB Wealth40,640$97.5K0.01%00.0%Unchanged
Deutsche Bank AG38,737$93.0K0.00%−1,552−3.9%Reduced
Bank of Montreal40,001$87.6K0.00%+40,001New
Manufacturers Life Insurance Company, The35,546$85.3K0.00%+17,326+95.1%Added
Balyasny Asset Management LLC34,433$82.6K0.00%+34,433New
ProShare Advisors LLC33,746$81.0K0.00%+2,764+8.9%Added
New York State Common Retirement Fund33,733$81.0K0.00%+63+0.2%Added
MetLife Investment Management32,862$78.9K0.00%+32,862New
Prosperity Financial Group, Inc.31,500$75.6K0.05%00.0%Unchanged
Victory Capital Management Inc31,369$75.3K0.00%−818−2.5%Reduced
Wells Fargo & Company31,015$74.4K0.00%+4,280+16.0%Added
BBR Partners, LLC30,000$72.0K0.01%+30,000New
State Board of Administration of Florida Retirement System29,400$71.4K0.00%+5,338+22.2%Added
Voya Investment Management LLC28,969$69.5K0.00%−8,390−22.5%Reduced
Tiaa Trust, National Association27,057$64.9K0.00%+57+0.2%Added
Cerity Partners LLC22,512$54.0K0.00%+22,512New
Principal Securities, Inc.20,000$48.0K0.00%−1,500−7.0%Reduced
SG Americas Securities, LLC19,269$46.0K0.00%−24,524−56.0%Reduced
Tower Research Capital LLC (TRC)18,037$43.3K0.00%+2,116+13.3%Added
Citigroup Inc17,548$42.1K0.00%−207,450−92.2%Reduced
HRT Financial LP16,965$40.0K0.00%+16,965New
JustInvest LLC15,485$37.2K0.00%+312+2.1%Added
Kestra Advisory Services, LLC14,500$34.8K0.00%+14,500New
Truist Financial Corp13,000$31.2K0.00%+500+4.0%Added
North Star Asset Management Inc12,550$30.1K0.00%+12,550New
Coyle Financial Counsel LLC12,500$30.0K0.01%+12,500New
Pinnacle Wealth Management Advisory Group, LLC12,445$29.9K0.00%00.0%Unchanged
Vermillion & White Wealth Management Group, LLC12,415$29.8K0.02%+12,415New
Chemistry Wealth Management LLC12,000$28.8K0.01%00.0%Unchanged
Berger Financial Group, Inc10,929$26.2K0.00%00.0%Unchanged
Susquehanna International Group, LLP10,843$26.0K0.00%−406,970−97.4%Reduced
Raymond James & Associates10,841$26.0K0.00%00.0%Unchanged
Captrust Financial Advisors10,811$25.9K0.00%−33,825−75.8%Reduced
Cetera Investment Advisers10,675$25.6K0.00%+10,675New
Principal Financial Group Inc10,534$25.3K0.00%00.0%Unchanged
Estabrook Capital Management10,000$24.0K0.00%00.0%Unchanged
LifeSteps Financial, Inc.10,000$24.0K0.02%00.0%Unchanged
River Wealth Advisors LLC10,000$24.0K0.00%+10,000New
California State Teachers Retirement System9,316$22.4K0.00%−5,933−38.9%Reduced
Ameritas Investment Partners, Inc.8,867$21.3K0.00%+3,500+65.2%Added
Legal & General Group Plc8,212$19.7K0.00%−2,946−26.4%Reduced
Nordwand Advisors, LLC4,000$9.60K0.00%+4,000New
Amalgamated Bank2,409$6.00K0.00%−7,538−75.8%Reduced
Metropolitan Life Insurance Co2,495$5.99K0.00%+2,495New
Royal Bank of Canada2,168$5.00K0.00%−26,917−92.5%Reduced
Quintet Private Bank (Europe) S.A.1,749$4.60K0.00%−179−9.3%Reduced
National Bank of Canada2,200$3.91K0.00%00.0%Unchanged